Basic Information

Insect: Tachinus rufipes
Gene Symbol: topi
Assembly: GCA_963932245.1
Location: OZ010743.1:1837419-1846584[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00073 0.19 14.6 2.4 2 21 121 140 120 141 0.94

2 13 8.5e-07 0.00022 23.8 0.7 1 23 166 188 166 188 0.97

3 13 0.0084 2.2 11.2 1.9 3 23 196 216 195 216 0.95

4 13 1.5e-06 0.0004 23.0 1.6 2 23 320 341 319 341 0.97

5 13 0.08 21 8.1 0.0 1 21 347 367 347 368 0.92

6 13 0.08 21 8.1 3.6 2 22 384 404 383 407 0.87

7 13 0.17 45 7.1 0.2 1 23 520 543 520 543 0.96

8 13 0.0035 0.92 12.4 0.4 1 23 547 569 547 569 0.97

9 13 1.4e-05 0.0038 19.9 5.4 1 23 575 597 575 597 0.98

10 13 0.029 7.6 9.5 0.2 1 23 603 628 603 628 0.96

11 13 0.14 38 7.3 2.9 1 23 634 656 634 656 0.86

12 13 1.8e-06 0.00048 22.7 0.5 1 23 662 684 662 684 0.98

13 13 1.3e-05 0.0033 20.1 1.9 1 23 690 713 690 713 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00073	0.19	14.6	2.4	2	21	121	140	120	141	0.94
2	13	8.5e-07	0.00022	23.8	0.7	1	23	166	188	166	188	0.97
3	13	0.0084	2.2	11.2	1.9	3	23	196	216	195	216	0.95
4	13	1.5e-06	0.0004	23.0	1.6	2	23	320	341	319	341	0.97
5	13	0.08	21	8.1	0.0	1	21	347	367	347	368	0.92
6	13	0.08	21	8.1	3.6	2	22	384	404	383	407	0.87
7	13	0.17	45	7.1	0.2	1	23	520	543	520	543	0.96
8	13	0.0035	0.92	12.4	0.4	1	23	547	569	547	569	0.97
9	13	1.4e-05	0.0038	19.9	5.4	1	23	575	597	575	597	0.98
10	13	0.029	7.6	9.5	0.2	1	23	603	628	603	628	0.96
11	13	0.14	38	7.3	2.9	1	23	634	656	634	656	0.86
12	13	1.8e-06	0.00048	22.7	0.5	1	23	662	684	662	684	0.98
13	13	1.3e-05	0.0033	20.1	1.9	1	23	690	713	690	713	0.98

Sequence Information

Coding Sequence: ATGAATAGAAGTGAACATattgcatatttaaaactaCATAGGATGTACACAGATGGGACATCACAATCCGTCCAATTGAGAATCGATTGTAGAACGCAGAAAATTATAGGTAGAGTACCGATAAATACAGATTTACCACCGCATTACGCCGACATGGATCCGAGTAAGTTTAAATTCAATTACACAATGAATTTTAAAGATAGTTCCATAAGAGTCATCAAATTGGGCGGTGTTGAAGATTTGAATCCATTAAATTATGCTACGGAAATCAGTACTGTCTTGACCGAACCTAGCgagaaaattattagaaatgcCGCCAATAAACGTGAGTCTAAAGTTCCTAATATACCTACAATGATTAGATGCCAGAATTGCGACACTAATTTCCCAACTAAGTACCAATTTCAACGACATCAATGCGAATTTAATGCCGAGAAAGTTGTATTGAAACCCAACGTTGATGTTAAGGATGTTGAAAAGGGTGTTAGGATGAAATTTGATTGTCCAACATGTGGAAAACAATTTgttagtaaaaacaatttagaacgACATCTAACAAGCCATGATGAGGATAACGTAAACATATGTGAGTATtgcaacaaacattttgttagtGAAAATCGGTTACGGATTCATAAAGAAAATCATTGCAAAAAGGCGGGtgatattagtaaattttatcgTAGCGACGTAACCGTTTGGAAATGTATAAAATGCTACCAAGTATTTTCATCCGATTCCTACGCTAACATGCATGCCGACAATTGTAATGACATACTTGATTTAGAAGAATTTCGTCGACACACGCGTCTAGATCCAAGCGatgaaagtaataatttaaaggAAGAAATTAAAACGCTTTTAAGCGAAGCCCCTGAATTAGCAGAGGCTGAAATCACCACAGTTAACATAAACACAAGCAAATATGTTGAGAAGGTTTTAACAGAATTATTGTTACAATGCgaatattgtaataaaacttattCCGATAAAAAATCGCTTTTAATCCATCAAAAAACTCACACAACTTTAACCAATTATAATTGCGTAATATGCGATGAAATATTTGAATCTTACTCATTAGCAGCGAAACATTGGTTAACAAAATGTTCAAACGAAGCCAATTTATTCTACTTACCCAAATTAACTTACTGTCGCTATTGTGATCGCACATTTAAATCGCACGAAGTTTTATATtctcacaaaattaaaaagaagcaTTACAGTCCTAAAAAATACATCCCATTACACAATCAACCCGAAAAGCAGCAAAAGGAGGAAAATAAAGAAACCATAATCAAATTAATCGAAGATGTACTTTGCTCAATCAAATTGAATGTTAATAATGATCAATTCAATAGCGACAAGGAAACTGAGAAGGATGTTTCTATTAAAACGGAAGTCATGAGTGAAACTAGCAGTTTAATTATTTCGGAGGATAATCAGGATGGCGATGTTGTTATAACCGGAAAGAAGAAGCGTGGACGGAAAAGGAAACATGTTTCGCAAACTAACAAAGCCAAACGTTTATCAGCGAATGTTGATCCCGGTTATAAATATCAGTGCGAACGTTGTGTTAACGTTTTTGATACTGTATTGGATTTGGAGACGCATAGGGATAAGGAGCATCCGGCTAATTACAAATGTGAGGAATGTGACcaggtAGTTCACAGTTCCAAAGCGCTATTGATTCACAGCAGAGCTCACCAGAGTTTGAAGCCATACGTTTGCGAGATTTGCAAACGATGCTACTCGCAAACATCACATCTCTGGCAACACATGCGATTTCATCAAGgAATCAAGCCGTTTGCCTGTCCACATGAAGGATGCGAAGCCCGCTATACCATCCGTCCCGATCTTAAAGATCACATCCGTAAAGTCCATACACGCGAAAGACCTTTCAAATGTTCGGTATGCGACAAATGCTTCCTAACCGGCTCAGTTTACTACCAGCACCGGTTAATACATACAAACGACCGCAGATATGCATGCGATatctgCAACAAGAGATTTTTCCGAGCGGATGCACTAAACAATCACAGAAGGATCCATACCGACGAGCGACCATATCCATGCGACGTATGTGGACGCCATTTTAGACAGAAAGGAGATAGGAATAAACATGTCCGTACACAGCATCCGGAATACCAtgtgtaa
Protein Sequence: MNRSEHIAYLKLHRMYTDGTSQSVQLRIDCRTQKIIGRVPINTDLPPHYADMDPSKFKFNYTMNFKDSSIRVIKLGGVEDLNPLNYATEISTVLTEPSEKIIRNAANKRESKVPNIPTMIRCQNCDTNFPTKYQFQRHQCEFNAEKVVLKPNVDVKDVEKGVRMKFDCPTCGKQFVSKNNLERHLTSHDEDNVNICEYCNKHFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCIKCYQVFSSDSYANMHADNCNDILDLEEFRRHTRLDPSDESNNLKEEIKTLLSEAPELAEAEITTVNINTSKYVEKVLTELLLQCEYCNKTYSDKKSLLIHQKTHTTLTNYNCVICDEIFESYSLAAKHWLTKCSNEANLFYLPKLTYCRYCDRTFKSHEVLYSHKIKKKHYSPKKYIPLHNQPEKQQKEENKETIIKLIEDVLCSIKLNVNNDQFNSDKETEKDVSIKTEVMSETSSLIISEDNQDGDVVITGKKKRGRKRKHVSQTNKAKRLSANVDPGYKYQCERCVNVFDTVLDLETHRDKEHPANYKCEECDQVVHSSKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYACDICNKRFFRADALNNHRRIHTDERPYPCDVCGRHFRQKGDRNKHVRTQHPEYHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01096881;
90% Identity: -
80% Identity: -