Omur010480.1
Basic Information
- Insect
- Ontholestes murinus
- Gene Symbol
- topi
- Assembly
- GCA_963969525.1
- Location
- OZ018387.1:31654971-31657831[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00059 0.21 14.6 2.4 2 21 128 147 127 148 0.94 2 12 6.9e-07 0.00024 23.8 0.7 1 23 173 195 173 195 0.97 3 12 0.0069 2.4 11.2 1.9 3 23 203 223 202 223 0.95 4 12 4.3e-06 0.0015 21.3 1.2 2 23 307 328 306 328 0.97 5 12 0.065 23 8.2 3.6 2 22 371 391 370 394 0.87 6 12 5.6 2e+03 2.1 0.6 1 23 507 530 507 530 0.86 7 12 0.0029 1 12.4 0.4 1 23 534 556 534 556 0.97 8 12 1.2e-05 0.0041 20.0 5.4 1 23 562 584 562 584 0.98 9 12 0.024 8.3 9.6 0.2 1 23 590 615 590 615 0.96 10 12 0.12 41 7.3 2.9 1 23 621 643 621 643 0.86 11 12 1.5e-06 0.00052 22.8 0.5 1 23 649 671 649 671 0.98 12 12 1e-05 0.0036 20.1 1.9 1 23 677 700 677 700 0.98
Sequence Information
- Coding Sequence
- ATGAACAGGAACGAGCATATAGCCTACCTGAAATTGCACAAGATGTATTCGGATGGAGTGGTGCAGTCCGTGCAGCTGAAAGTCGACTGCAAGACGCACAAAATCGTGTCGCGGATGCCTACGGCTTCAGATTTGCCCCCCGATTACGTGCAGCACTTCGGCGACTGCGAGGATAAGTTTAAGTTCAATTGCAGCGTGAACTTTAATGATTCGTCTATAAGAGTGATTAAATTAGGCGGTGTTGAAGATTTAAACCCGCTAAACTATGCCACGGAGATATCTACCGTGTTGAACGATCCGGTTGGGGCTAAAGTGACCAGTACACCGCCGGCGATAACTCCGAAGCGGGAATCAAAGGTCCCCAACATACCTACGATGATTAGGTGCCAAAATTGCGATACTAACTTTCCTACGAAATACCAGTTCCAGCGGCATCAGTGTGAATTCAATGCTGAAAAAGTTGTGCTGAAACCGAACGTGGACGTTAAGGATATTGAAAAGGGGGTCCGGATGAAATTCGATTGCCCCACTTGCGGAAAACAATttgttagtaaaaataatttagaacgtCATCTTACCAGTCACGACGAGGATAACGTAAATATCTGTGAGTATTGTAATAAACATTTCGTTAGTGAAAACAGGTTGAGGATCCATAAAGAAAACCATTGTAAAAAAGCTGGTGACATCCTCAAATTCTACAGGAGTGATGTAACTGTTTGGAAATGCATTAAGTGCTATCAAGTTTTCTCCTCAGATTCTTACGCAAGTAATCATGCTGATAGCTGTACCGACATTTTAAATGTCGAAGAATTTAATTCACATAAGTTAAATCTGGACGCAATTGGTTTAaaagaagaaactaaaaatgaacTTTCGAATAGATATGTTGATAAAGTTCTAACAGAACTGCTATTGCAATGTGAATACTGCAATAAAACTTATGCTGATAAAACTTCCTTATTAATGCATCAAAAAACGCATACTACAGAAACGAATTATAATTGTGTTATTTGTATGGAAACGTTTGATTCGTATATTTTAGCTGCAAAACATTGGCTTACCAAATGTTCTAATGAAGCCAACTTATTCTATCTACCCAAATTAACTTATTGTCGGTATTGTGATAGGACTTTTAAATCCCACGAGGTCTTGTACtcgcataaaataaaaaagaaacactaCACACCGAAAAAGTTTTTGCATTCAGAACCAATAGAGACTGTAGATATTGTTGATAAAGAGGAAAACAAGGAAACGATCATAAAGCTGATTGAGGATGTGCTGTGTTCCATCAAATTGAATGTTAACGAGAACAGGGAGAGACCGTTGGAGGAGAGCGAGATCACCGTCAAAACGGAGGTAATGAGCGAGACCAGCAGTCTGATTATCTCGGAGGATGCGCAGGAATCGGACTTGCTCGTCGCGGGTAAGAAGAAGCGCGGCAGGAAGCGTAAGCACGTTTCCCAGACGAACAAAGCCAAACGTTTGGCGGCTAATGTTGATCCGGGATATAAGTACCAGTGCGAACGGTGCATTAAAGTTTTCGACTGCGTTCTAGATTTAGAAGCTCATCGGGATACTGACCATCCTGCTAATTACAAGTGCGAAGAATGCGATCAGGTGGTGCATAGTTCGAAAGCCTTACTAATCCACAGTAGGGCCCATCAGAGCTTAAAGCCGTACGTTTGCGAAATTTGCAAACGTTGCTACTCACAAACCTCCCACTTGTGGCAACACATGCGCTTCCACCAAggCATTAAACCTTTTGCTTGTCCGCACGAAGGCTGTGAAGCTAGGTACACCATCCGACCAGATTTGAAGGACCATATTAGGAAGGTCCATACCAGAGAAAGGCCTTTCAAGTGTTCAGTCTGCGATAAGTGCTTTTTGACAGGATCAGTTTACTACCAGCACCGATTAATACACACTAATGATAGAAGATATGCTTGTGATattTGTAATAAGAGATTTTTCCGAGCTGATGCACTGAATAATCATAGAAGGATACATACCGACGAACGACCCTATCCATGTGACGTGTGTGGAAGACATTTTAGGCAGAAGGGAGACAGAAATAAGCACGTACGCACTCAGCATCCGGATTACcatttgtaa
- Protein Sequence
- MNRNEHIAYLKLHKMYSDGVVQSVQLKVDCKTHKIVSRMPTASDLPPDYVQHFGDCEDKFKFNCSVNFNDSSIRVIKLGGVEDLNPLNYATEISTVLNDPVGAKVTSTPPAITPKRESKVPNIPTMIRCQNCDTNFPTKYQFQRHQCEFNAEKVVLKPNVDVKDIEKGVRMKFDCPTCGKQFVSKNNLERHLTSHDEDNVNICEYCNKHFVSENRLRIHKENHCKKAGDILKFYRSDVTVWKCIKCYQVFSSDSYASNHADSCTDILNVEEFNSHKLNLDAIGLKEETKNELSNRYVDKVLTELLLQCEYCNKTYADKTSLLMHQKTHTTETNYNCVICMETFDSYILAAKHWLTKCSNEANLFYLPKLTYCRYCDRTFKSHEVLYSHKIKKKHYTPKKFLHSEPIETVDIVDKEENKETIIKLIEDVLCSIKLNVNENRERPLEESEITVKTEVMSETSSLIISEDAQESDLLVAGKKKRGRKRKHVSQTNKAKRLAANVDPGYKYQCERCIKVFDCVLDLEAHRDTDHPANYKCEECDQVVHSSKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYACDICNKRFFRADALNNHRRIHTDERPYPCDVCGRHFRQKGDRNKHVRTQHPDYHL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01400638;
- 90% Identity
- -
- 80% Identity
- -