Basic Information

Gene Symbol
-
Assembly
GCA_944452685.1
Location
CALYBZ010002345.1:24379-31293[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.18 18 7.0 0.6 1 23 271 294 271 294 0.93
2 13 0.092 9 7.9 1.1 2 23 369 391 368 391 0.92
3 13 0.00067 0.065 14.6 0.5 1 23 784 806 784 806 0.98
4 13 0.00035 0.034 15.5 3.0 1 23 812 834 812 834 0.97
5 13 0.00045 0.043 15.2 2.5 1 23 842 864 842 864 0.98
6 13 0.00031 0.03 15.7 0.7 1 23 870 893 870 893 0.97
7 13 0.087 8.5 8.0 0.2 1 23 1031 1053 1031 1053 0.97
8 13 0.00052 0.051 15.0 0.4 1 23 1059 1081 1059 1081 0.97
9 13 0.014 1.4 10.5 6.2 1 23 1087 1109 1087 1109 0.98
10 13 4.7e-05 0.0045 18.3 0.1 1 23 1115 1137 1115 1137 0.97
11 13 4.6e-05 0.0045 18.3 2.7 1 23 1143 1165 1143 1165 0.98
12 13 0.0031 0.3 12.5 2.3 1 23 1173 1195 1173 1195 0.99
13 13 4.7e-05 0.0046 18.2 0.2 1 23 1201 1224 1201 1224 0.97

Sequence Information

Coding Sequence
ATGATCAACACTTTGCTGGAGCATGTGCCCATCAAAATGGAAGTTACAGACAATGATGAGGCTGCTGACAAAGCAGCAAATGCTGAATTGGCAGAAGATGATGACAGAATTGATGAGACCGATGAAGAACTAGATGATGAAGACGAAGATGAAGTTTCAGATACTGAAAGCGATGCTTTAGAAATTGAACAGCAGGCTATTATGTTGATAAGCAGCGATGAAGAAGCTGAACTGGAGGCACAGAGAATACGTTTTCCAGATATTGCAAGTGCCAAGAAATTGCGCAAAGATTCCTATAGTTCAACGCGGAGCTCTTCGAGAAACAGCCAAACGAGCAGTTGTTCATCATCCTCCAAGCCACATATTACCTACGAAATTATAACTAGAAATCCGACCATAGAAAAAACCAACAACGAACAAAGAATTTCACCTTTATTGAAGAATAATGGGAACAATAAAACTTTGGAGATCTGTAATAAAGAAAACAGTAACAGTGCACAAACTAAGGTAAAAAGCAAAACGGAGAACAGCAGCAAGCTCGAAAATAACAAAACTTTGGAAAATAATAAAAATAAACATAACGAAGCTACCAAATGTGTGGATAAGATTAAAATAAAGAAAACTTCCGAAAATACACGCAACAATCGAGATCATTTACTCAAATGTCCAGGTAATGTTGTTACCGGAGAAAAAAGCCGCCGTGGCAGTAACAATTCTGCTTGTAGTGTTGCATCTACTCTGGTCTCCGAGAGAGCCGAGACTGAATCTTGTGGCAATATTTATGTCTTTAATTTGCAGCAGAAACTTATATTTAATTGTGAGTTTTGTGATTTAAAATATGGCGACCTGGCGAATTTTGGACGACATCTGCATGAAGCTCATAAAGTTTTCAACATGCACGAAGGTGCCGAGAAGGAAAACGCACCAGGAAATTTACCCAAAAGCAGTCGCATATCTAATAATGCGCCAAATGTTAAAAAGGAACCTTTGCAGAGCTTAGAAGTATTGGCTGCGCCACCTGTTGCTCTGCCGGCATCTGTTTTGGCAGAACCTCTAGACTCGTGTGGCAATGTGTTTATGCTTAATCATCGTAAATTGTTTTTGGTTTGTGGATATTGTGAATGTAAATATGCCAACTTGGATTTGTTTGAAAAACATTTGACGCAGCAGCACCGTATTTTTGAGGGCTGCCGCAATGAGTTGAATGTGGTGCCTAAGGTAGAGGTCAAAGAAGAGGTATTTATTATCACAGAAGTAGTGGATAACCAAAATATAGTAGTAGCTCCCGATGCCATGGTAATCATACCAGCTGACATTCCTTTAAATATATCTGACCCAATACAAAATGACGAAACGACGATACCAGCTTTAGAGGAAAGGGTGGAAACTAGTATGCAATGTAGCAAAGAAAAGTCCAAATCTTCTTCCATTGATTTAGTAACGGAAAACTTAAAATCTAAAGATAAAGTCCAACCCAATAGCAGCGAAGTTAAGGTGGTTTCAGAAAAGGAAGAAAATGAAATGCCAAAAGTTGTGGATAATAAGGAAGAGTCACCCGCTAAGAATGTCGTAGATAATGAAACAACATTGCCTGCCGAAGTCGTTAATAATGAGTTATCATTGTCTCCTAAGCAGGTTATGAATGAAGAAATAATTTCGACTAAGCCAGCGGAAATTAAAAGACTATCTTCAACACCACTAGAATCGCCGAGCAAAAAGGCTAAAAGAGAAGCGCCAAGTAACACAAATGTTCAGCAGGAGGAGCCCATTGTCGCTAAGAAAGCCGACGAGCTTCCCACAACAAGTTTAGAAAATACAGAAGTTATAAGAACAAAAGAAATTCCAGAACCGCCAACAATAAAAGAAGCACAAGATTCCAGTAAAAAGTCCGTAGAAATAGCAGAATCAATAAAAGTAGCAAGTCAAGAGGAGATTACAGAAATAAAGTCAATAAAAGTTACAAGTCAAGAGGAGATTACAGAAATAAAAGAAACAAATGTACCTATAAAATCTATGGAACCAAGAAAGCAGGCAGAAGAAGCACAAACAAAAAATCCAGCAGCAACTCAAGCAGCTAAAGAAAGTGAACCAAGTAAAGCAACAAAAGCAGAAGTAGCAGCGGCATCACAATCACCACCGTCACCACCACCACCAACACCACCAACACCACCACCACCAACAACAACAACAGCAACACCAACAACAACAGCAAAATTGGTAGAGGCCAAAAAACGAACACTGCCTGAAATACTGGCCACGAAAGACTCTCGAAAAACAACCAAATCTCCCCAAATGAAAAAACTCAAAGAGGAGAAAACTGAAATTGAATCAATTCCTAATGAGCGAAAATTTGAGTGCTCAATATGCCTCAAGGAACTCTCTAGTAAATACTCTTTGATACTTCACGAACGCACACATACCACAGATAAAACTTACGAGTGCGAGGTCTGCCACAAAAACTTCGAGAGCAGCTCAAGTCTCAGCGACCACAAAAAGTTTCACACGAATGAGTCACAAGAAATACACAAGTGTACAGTTTGTGATATAGAGTTTATGCATAGCGATGATTACAAAAACCATATGGAAATCCACTCCAATGAGAAAAAGTTTAAATGTGATATTTGCTTGCGTGGCTACTCGTCCAAGAGCAGTGTGCGCAAACATATCGAAAGAGATCATAAAACGAAAAAAGAAGCTGCAAAATGTAAAAGGAAATCAGCTAGGAGACAGGATGTGCCGAGCACGAAACTTGAAAAACCAGCAGAACCACAACTGCCCACAATCTCCTCTTCCTCATCAATAAATGAGAAAATAGAAGAAACATCCGTTGCCCAAGCAAACGATGTAATGAATGATTTTGAGACTGATCCAGTCGAAGACATTATTGAACAATTGCAAAATGAAATGGTGGAAAAAGAATTACGACCTGGCGAGATCCATCCAATAACTTACACTGTTAAAGCTGTCGAGCCAGAGGGAGAAGTTAAAGTGAAATCTTTGAAGACTGGCTCAGTAAACTCTGACGCCGAGCTCAATGAAACGGATACATCAGTGAAAGGTAAAACCAAGGTTTTGCAAATCATTAAACGTTTCTTCTGTGATGTATGTCCTAGTGGATTCGAAAAGCAAGCACGTCTGCTGGAACATAAACGTGTgcatacgggcgaaaagcctttcccttgcgatgaatgcgataaacaattccgtgtacgtataggcttgaaagaacataaattaaggcataccaacgaaaagaaatttaaatgtgaagtctgtggcttgggctgttttaccaaacaagacctgcatatgcatatgcgtcatcattccaacgatcgccgttaccagtgcatcatgtgccccaaggcctttgtgcgtagttctgatttgaaaatacatgcgcgcatccatactggcgagaagccatatgtatgcgatatttgtaacaaatctttccgagccaatcaaaacctgtgcgttcacaaaaaatctcatatgggcgaagcgtccagaatctacaaatgtgatcgttgtgacaagaagtttttgcgtaatatcgatcgcaaagtccacatgagatcgcatacgggcgaaaagcctttcaagtgcgaggtttgtcaacgtggcttctcctcgaaagtcaatgtacgagcccacatagaaagagaacatatatcggagaaaacttcgaaatCCAAAAAGAAACCAGGACCCAAACCCCAAGCCCTAAGGGATGAGATAGCAAAGCAAAGAAAATTGATACAGGAACTGCAAAGCCAACTATGGCAACAAATTCAAACCGAGGAAAAAATCATACCATCCGATGAGGAAATGTTGGAGCAGCAGCAGCAAACATTACACGATTCCAATACAAAAACCACTTCTTCCGCGAACACGACGAAAACCAGTAATAGTGATCCTATACAAAGTGCTTACAAATTGCTAGACAAACTGAAATCATCAACAACTACCTCCAAACCTTTAACTGCAATACCATCGCCTCCACCGATGGGCGAACCACTCGCTGCAATTCCCTCGAAAAAAAGCAAAAAAGACTCAACAACTTTACTACCTCTTACTATAACGCAAAAACTAGAACAGGCTTCACCAGCACCCTCACCCTCAACGGCTACCTCCTCATCTACTTCTACTTCTACTTCGCGCCGTTCTACACCCTCCCCACCCAAGACCACTGCTACCAAGGTAGTGTCTCAAAAGACCTCATTGGGCATCCAGCAAGTATCGGTGACAGTTTCTATGCAAGTGGAAAATGTTGCACCAACTCCCAGCGCTCCCGAAAAAGAAAATGGTGGTATTTTGACGACATGCTCCAGCAGTACAAATAGTGTTAAAAAAGAAAGAAAGATCACAAGTTATTTTACGGTAGTGGGCCAAAAGGCTGAAGTTTAA
Protein Sequence
MINTLLEHVPIKMEVTDNDEAADKAANAELAEDDDRIDETDEELDDEDEDEVSDTESDALEIEQQAIMLISSDEEAELEAQRIRFPDIASAKKLRKDSYSSTRSSSRNSQTSSCSSSSKPHITYEIITRNPTIEKTNNEQRISPLLKNNGNNKTLEICNKENSNSAQTKVKSKTENSSKLENNKTLENNKNKHNEATKCVDKIKIKKTSENTRNNRDHLLKCPGNVVTGEKSRRGSNNSACSVASTLVSERAETESCGNIYVFNLQQKLIFNCEFCDLKYGDLANFGRHLHEAHKVFNMHEGAEKENAPGNLPKSSRISNNAPNVKKEPLQSLEVLAAPPVALPASVLAEPLDSCGNVFMLNHRKLFLVCGYCECKYANLDLFEKHLTQQHRIFEGCRNELNVVPKVEVKEEVFIITEVVDNQNIVVAPDAMVIIPADIPLNISDPIQNDETTIPALEERVETSMQCSKEKSKSSSIDLVTENLKSKDKVQPNSSEVKVVSEKEENEMPKVVDNKEESPAKNVVDNETTLPAEVVNNELSLSPKQVMNEEIISTKPAEIKRLSSTPLESPSKKAKREAPSNTNVQQEEPIVAKKADELPTTSLENTEVIRTKEIPEPPTIKEAQDSSKKSVEIAESIKVASQEEITEIKSIKVTSQEEITEIKETNVPIKSMEPRKQAEEAQTKNPAATQAAKESEPSKATKAEVAAASQSPPSPPPPTPPTPPPPTTTTATPTTTAKLVEAKKRTLPEILATKDSRKTTKSPQMKKLKEEKTEIESIPNERKFECSICLKELSSKYSLILHERTHTTDKTYECEVCHKNFESSSSLSDHKKFHTNESQEIHKCTVCDIEFMHSDDYKNHMEIHSNEKKFKCDICLRGYSSKSSVRKHIERDHKTKKEAAKCKRKSARRQDVPSTKLEKPAEPQLPTISSSSSINEKIEETSVAQANDVMNDFETDPVEDIIEQLQNEMVEKELRPGEIHPITYTVKAVEPEGEVKVKSLKTGSVNSDAELNETDTSVKGKTKVLQIIKRFFCDVCPSGFEKQARLLEHKRVHTGEKPFPCDECDKQFRVRIGLKEHKLRHTNEKKFKCEVCGLGCFTKQDLHMHMRHHSNDRRYQCIMCPKAFVRSSDLKIHARIHTGEKPYVCDICNKSFRANQNLCVHKKSHMGEASRIYKCDRCDKKFLRNIDRKVHMRSHTGEKPFKCEVCQRGFSSKVNVRAHIEREHISEKTSKSKKKPGPKPQALRDEIAKQRKLIQELQSQLWQQIQTEEKIIPSDEEMLEQQQQTLHDSNTKTTSSANTTKTSNSDPIQSAYKLLDKLKSSTTTSKPLTAIPSPPPMGEPLAAIPSKKSKKDSTTLLPLTITQKLEQASPAPSPSTATSSSTSTSTSRRSTPSPPKTTATKVVSQKTSLGIQQVSVTVSMQVENVAPTPSAPEKENGGILTTCSSSTNSVKKERKITSYFTVVGQKAEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01074716;
90% Identity
iTF_01398774;
80% Identity
-