Basic Information

Insect: Tachina fera
Gene Symbol: egg_1
Assembly: GCA_905220375.1
Location: LR999967.1:107189743-107197378[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 6.3e-13 4.9e-09 37.0 0.0 5 74 1390 1452 1387 1455 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	6.3e-13	4.9e-09	37.0	0.0	5	74	1390	1452	1387	1455	0.90

Sequence Information

Coding Sequence: ATGTCTGAGATTGAAAACAAAGATGATATTGTGCAGAAGTGCACCAATGAGACTCCTCTAGATTCTGTATCTGGAGATATTGAAATGCCGGTCTTGCAATCAGCTCCAGAAGATGCCTCTAATAAAAACCATGATATATTAGTGACCGGAAAACAAGATACTGCACAAAGTATGAAAGTTAATGACAATACGGATGAAGGTAATGATGGAAAGGTTTTGACGCCTATGGGAGAGAACTTGGAGCTTACAGCAGctgaAATATTCCACTTTATGTCTAACGAAGATTTTGATGACATAGAGAATACAAGCAATCCGGAAAAATCAAGAAAAGAAGAAATAGATAATATCGAACCTGTTATTGTTGCATTAACCGCAGAATGCTCGAAAGAAATTGTTGCCAATGACGAGAACTTAAAAGCAAGCGGGGCAGAAGAGTTATCTTCAGGTCAAGAAAATATAAATCCAATATACGAAGAAGTCACCAAGTCTTCAATAAATGAAAGTCCAAAGAAGGAAAAAGAAATATCTTCAATATCACAGAAATCGTGTACAACTGAGGAAATATCTTCAGAAGTAACATTTGAAACTAATGCTGAAACAAATACAATAGACGTAATACAAACTTTACAGACGGAAGCAGAAGATGATCAAAACGATAGCACTAAGTCTCCAAGTCTTACTAAAGACTTAGATTTGGCTGATACACCAGTTGTGGAAGACAATGTTGTGCTTCCATCTATCTCAATGGAAGCTGAAGAAGATGtgaaagaaaatcaaaataattatgctAAAGATGATAAAACCAATACCGCTAAATCTCCAAGCCCTACTACAGATTTGGCTTCGACTGATATACAAGATGCGGCTTTAGAGGTAAATGTTGCTCCCATATCTATCCCAATGGAAGCGGATGAAGTAGTGAAAGACAAAGATAACGAAGCAAAAGATGATCAAACCAATTGCGCAGTGTCTACAAGCATCACTAAAGAAGATATACAAGATGCAGTTTTAGAGGAAAATGCTGTTCCCACGTCCATCTCAATAGAAGCTGATAAAGTTGGTGAATCAAATCTAGATGGTGAATCAAACAATGATCAAACCAATAGCACTGAATCTACAAGGCTTACTCAAGAAGATTTGCTGTTGACTGATACAGAAAATGCAGTTTTAGATGAAAATTGTGTTCCAACATCAATTTCAATGGAAGCTTTGGCTTTGAATGATATACAAAATAAAGATCTAGAGGAAAATGTTGTCCCCACATCAATGGAAGCTTTGGCTTTGAGTGATATACAAGATGTAGCTTTAGAGGAAAATATTGTTCCGACATCCATATCAATGGAAGCTTTGGATGATATACAAGATGTAGCtttagagaaaaattttgttcccACATCCATATCAATGGAATCTTTGGCTTTGAACGATATACAAGATGTAGTTTTAGACGAAACTGATGTTCCCACATCAATACCAATTGAAAGTTTGGCTTTGAATGATATACAAGATGTAGTTTTAGAGAAAAATGCTGTTCCCACATCTATCGCAATAGAAGCTGATGAAgttctgcaaaaaaataaagatgGTTCAAAGAATGTTCAAACCAAAAGCACTGAATCTACAAGGCTTACTGAAGAAGATTTGCTGTTGACTGATACACAAAATTCAGTTTTAGAGGATAGTATTATGCCTACATGTGACGCAATCGAAGTTTTGAAAGAAAATCAAGATAATGGAGTTCCTACTGAGGAAGTCGTAGAACACATGGAGACTTGTGATAGTCAAGAATCTATCAATCTAGTAATTGATGAGGAAACTTCAAACAATGCGGAGGTGAAAGATGATTTCGCAGATATTAACAAAGCCGATGATGATACTAATATGGAAGTAGATGAAAACGAAGCAGCAGCAGATATAGACAACGAAACTGCGAAACTTcctgaaataaatgaaatagaaaaagaCGCTGAAACTGTTTTAGAAGAACCTAAAGAGAAAGATATTCTTAGCAAATCAAAAGAAGGCAATGCCGAAAAAGAGGCTGATTCTAAATTACAAATACCTCAAGAGATAGATATACTTAACAGTTCTAAAGATGATGATGTTATACCAATAGAACAACCACCAGTACCCATTATTGAAATTGATGATGAAGAAGAAATTGAAATCGATACCTCGACAAATGAAGCTGGTTCGAAGGAAGACCAAAATTTGAATCATGCTAATGAAAGTCCCAATGAAACTGTTGACTCAAATCAAGAAGACAACGTTATAGAGAAAACTATTATTGAAAATGGAACTAGTACTAGCGAAGGCAACGAAAACAAAGATCAGAGTGAAGATATATTATTGGAAAAGGCTTCAGAAAAACCTTTGAGCGATGATATAATTGCTGAGGAAACATCTACATCAGATGATATAGAAGAAACCAATGATGAGGTATTCTACAACAAGGAATGTATAAATTATGAGTGTCCTCATAAACATAAGCAATACTTTAAAGTACCACAATTTGCTTTTAGTTACTTTAAggtaacaaaaaagaaatttaaacccCAATATATCTGCGCCGATTGTTATGACAAAGCTTTGGAAATGTATGAGGAATTTTGTGGTTTAATAAATGCTAAGCAACCTTTACTTTTGGAAGACATACCCTCTGGCAGGCAAGAATTTGTTGAAATCATCGACAGTAGCGATGACGAAGACTCTATCAGTAACAAGGGCAAACTCGTACAGCCAACCAAAACAGCATTTTCCAAAAACGATTTGACTCTCATAGAGTCTGAACTAAATGATACAATTAAGGCGGTATTGAATAAAGTTCACATACAAAACCAATTAACTTGGTCTAAAACTATTCTGATGGAACGCCTGAAACGATTGGAAATGGAAACCGAATATGTCGATACCGAACTTAAAGTCTTACAAAAAAAGGCAGATAAAATGCATGAAGGTTTGTATACgtgcccaaaaataaaaatacgtcaAATGCAGCCGTTAGACTTGAACAGTGGCAAATTGATGAGTTTGGATCCAATAGTAACAAAAGAAGTTCAGCCTGTTCCACCTGTTGGCGAAATCGAAAGACCGGCCATTCTTCCAAATAGTATTTATTATGCAGTTAAAAATAATCCAATTGCAAGTTGGGTTCCTTGCAAAGTCATGGAACAAGTTGAAAGCGGTTTGACTAACCAAATTTCTTATAATGTAAAACAgttcaaaatcaaatttattagaaatcaaaCTCAAATGCCTAAAACCGTACCAGCCAAATATTTGGCGTATTATGATCCTCCATCTGTTAGATTGCCCATAGGAACTCGTGTTATTGCATATTTCGATGCCACTTCTTTGGCCAGAGGACGAGAGAAAATAAATGTGCAAAGCGCATTTTATCCTGGCATTATAGCAGAACCCTTAAAGCCCAACAATAAATTTAGGTATTTAATCTTCTACGATGATGGATACACCCAATATGTCTACCACAAAGATGTACGTTTAGTTTGTCACGTATCCGAATGTGTTTGGGAAGATGTTCATCCAGCTTCTAGGGACTTTATACAAAAGTATTTAACACAATATTCTATTAATCGTCCCATGGTACAAACCCAAAAAGGACAGTCTATGAATACCGAATCGAATGGCTACTGGTTACATGCTCGCGTCGTTGATATTGATTGCAGTTTGGTGCTGATGCAATTTGAAGGCAGTAAAAGCCATACCGAATGGATATATCGTGGTTCTTTACGCTTAGGACCAGTGTTCAAGGAATATCAAAAATCATTACAAAAGAATTCTACCATTCCGGTATCACGCTTACCAAGGCGCACGGAACCCTTTATACGTTATACCGAAGATGAAGAAAATACAagtcaacaacagcaacaggaTAAAACAGATGGAACTCGTGCCGTAGCTCGCAAAACATTTGGTAGACCAGAATCTATGATGAATTCGGCACAACCCACTAGTaaccaacaacagcagcaacaacctatcgttaaacatttaaataattctACTATTTACGTAGAAGATGAAAATAAACCTAAAGGAAAGGTAGTCTACTATACAGCCAAACGTAATTTGCCACCACGAAAATATAAGCCGCACAAGTGTGCGCCCTCATGTCAGTTCGAAATCACTCATAATCTCAGCGCTTATAGTCCTTTATCGAAGCCATTGCTCTCTGGTTGGGAACGTTTTATTATACGTCAAAAAATCAAACGTGTTGTTACTTATCGTGCACCGTGTGGCAAAATTATACGTAATATGAAAGAGTTACATCACTATTTACGTTTCACCAATAACGTTTTGAATGTGGATAATTTCGATTTTAGTCATGAAATTAGTTGTCTGGCAGAGTATGTTATTGAAAGTGCTATTATACAAAAGCGTGATATCTCCGGTGGTCAGGAAAAAATGGCCATACCGTTGGTGAACTATTACGACAACACCTTGCCTCCAGAATGTAAATATTCGGCTAAGGTTATACCTACTGAAGGTGTTAATATTAATACGGATCCGTCATTCTTAGTTGGATGTGATTGTGAGGACGATTGTGCCGATAAGACAAAATGTTCTTGCTGGCAATTGACTTTGTCTGGCGCCAAATATGGTAATCCAAATGCTGCTCCTGAAGAGGTAGGCTATCAGTATAGACGTCTACTAGATCATGTGCCAACCGGAATTTATGAATGCAATGCTAATTGCAAATGCAAAAGTAGTTGTCTTAACCGTGTTGTCCAAAATTCATTGACAATGAAGCTGCAAGTTTTTAAAACCTCTAATCGTGGATGGGGTCTACGTTGTATTAATGACATACCACGCGGCAGCTTTGTATGCGTATATGCTGGCCACTTGTTAACTGAAGCCAAAGCTAATGAGGGTGGCCAAGATGCTGGCGATGAATATTTTGCCGAATTAGACTATATTGAGGTGGCAGAACAAATTAAAGAGGGCTACGAATCAGATGTTGAGGTACCCGAGCCCGAAGAAGAAGACGCTTACCAGCCAGAAATGGATGATGACTTTACTCCAAGCAAGTCCTTTTTAACTAGAGCCAAGCAGAAACAAAGTGCGTTAAAGTCAACACGGCCCAATAACCAAGAAGAAGATTCGCAAGAGAGACAAGTGATTAATTTTAATCCAAATGCGGATATGAATGAAGATTCAGTTAGAGAAagTTCCATACGCAAGCTATATGGCAAAGATGAAGCGTGTTATGTAATGGATGCAAAAATTTCTGGCAATCTGGGTCGTTATTTCAACcattctTGTGCACCCAATATGTTTgttcaaaatgtttttgttgACACTCACGATTTGCGTTTTCCAAATGTTGCATTCTTTTCCTCATGTAACATACGTGCTGGCACTGAATTAACTTGGAATTACAATTACGAAGTAGGTGTGGTACCTGGAAAAGTTTTATACTGTCAATGTGGGGCATCCAACTGTCGCCTACGACTGCTTTAA
Protein Sequence: MSEIENKDDIVQKCTNETPLDSVSGDIEMPVLQSAPEDASNKNHDILVTGKQDTAQSMKVNDNTDEGNDGKVLTPMGENLELTAAEIFHFMSNEDFDDIENTSNPEKSRKEEIDNIEPVIVALTAECSKEIVANDENLKASGAEELSSGQENINPIYEEVTKSSINESPKKEKEISSISQKSCTTEEISSEVTFETNAETNTIDVIQTLQTEAEDDQNDSTKSPSLTKDLDLADTPVVEDNVVLPSISMEAEEDVKENQNNYAKDDKTNTAKSPSPTTDLASTDIQDAALEVNVAPISIPMEADEVVKDKDNEAKDDQTNCAVSTSITKEDIQDAVLEENAVPTSISIEADKVGESNLDGESNNDQTNSTESTRLTQEDLLLTDTENAVLDENCVPTSISMEALALNDIQNKDLEENVVPTSMEALALSDIQDVALEENIVPTSISMEALDDIQDVALEKNFVPTSISMESLALNDIQDVVLDETDVPTSIPIESLALNDIQDVVLEKNAVPTSIAIEADEVLQKNKDGSKNVQTKSTESTRLTEEDLLLTDTQNSVLEDSIMPTCDAIEVLKENQDNGVPTEEVVEHMETCDSQESINLVIDEETSNNAEVKDDFADINKADDDTNMEVDENEAAADIDNETAKLPEINEIEKDAETVLEEPKEKDILSKSKEGNAEKEADSKLQIPQEIDILNSSKDDDVIPIEQPPVPIIEIDDEEEIEIDTSTNEAGSKEDQNLNHANESPNETVDSNQEDNVIEKTIIENGTSTSEGNENKDQSEDILLEKASEKPLSDDIIAEETSTSDDIEETNDEVFYNKECINYECPHKHKQYFKVPQFAFSYFKVTKKKFKPQYICADCYDKALEMYEEFCGLINAKQPLLLEDIPSGRQEFVEIIDSSDDEDSISNKGKLVQPTKTAFSKNDLTLIESELNDTIKAVLNKVHIQNQLTWSKTILMERLKRLEMETEYVDTELKVLQKKADKMHEGLYTCPKIKIRQMQPLDLNSGKLMSLDPIVTKEVQPVPPVGEIERPAILPNSIYYAVKNNPIASWVPCKVMEQVESGLTNQISYNVKQFKIKFIRNQTQMPKTVPAKYLAYYDPPSVRLPIGTRVIAYFDATSLARGREKINVQSAFYPGIIAEPLKPNNKFRYLIFYDDGYTQYVYHKDVRLVCHVSECVWEDVHPASRDFIQKYLTQYSINRPMVQTQKGQSMNTESNGYWLHARVVDIDCSLVLMQFEGSKSHTEWIYRGSLRLGPVFKEYQKSLQKNSTIPVSRLPRRTEPFIRYTEDEENTSQQQQQDKTDGTRAVARKTFGRPESMMNSAQPTSNQQQQQQPIVKHLNNSTIYVEDENKPKGKVVYYTAKRNLPPRKYKPHKCAPSCQFEITHNLSAYSPLSKPLLSGWERFIIRQKIKRVVTYRAPCGKIIRNMKELHHYLRFTNNVLNVDNFDFSHEISCLAEYVIESAIIQKRDISGGQEKMAIPLVNYYDNTLPPECKYSAKVIPTEGVNINTDPSFLVGCDCEDDCADKTKCSCWQLTLSGAKYGNPNAAPEEVGYQYRRLLDHVPTGIYECNANCKCKSSCLNRVVQNSLTMKLQVFKTSNRGWGLRCINDIPRGSFVCVYAGHLLTEAKANEGGQDAGDEYFAELDYIEVAEQIKEGYESDVEVPEPEEEDAYQPEMDDDFTPSKSFLTRAKQKQSALKSTRPNNQEEDSQERQVINFNPNADMNEDSVRESSIRKLYGKDEACYVMDAKISGNLGRYFNHSCAPNMFVQNVFVDTHDLRFPNVAFFSSCNIRAGTELTWNYNYEVGVVPGKVLYCQCGASNCRLRLL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01074475;
90% Identity: -
80% Identity: -