Basic Information

Gene Symbol
-
Assembly
GCA_900474325.1
Location
UCOK01015887.1:27699-36286[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0092 1.1 10.4 0.2 1 23 712 734 712 734 0.98
2 17 1.7 1.9e+02 3.3 0.5 1 19 740 758 740 759 0.80
3 17 0.43 49 5.2 0.9 2 23 767 788 766 788 0.95
4 17 0.00018 0.021 15.8 1.5 3 23 797 818 795 818 0.96
5 17 0.0051 0.59 11.2 1.5 1 23 825 848 825 848 0.94
6 17 9.2e-05 0.011 16.7 0.7 1 23 854 877 854 877 0.94
7 17 0.15 17 6.6 1.4 2 23 885 905 884 905 0.96
8 17 4.1e-06 0.00047 21.0 3.2 2 23 911 932 910 932 0.97
9 17 6.7e-06 0.00077 20.3 0.3 1 23 938 960 938 960 0.98
10 17 0.00061 0.07 14.1 2.1 2 23 972 994 971 994 0.95
11 17 0.051 5.9 8.1 1.1 1 23 1000 1023 1000 1023 0.93
12 17 0.088 10 7.4 5.6 3 23 1046 1067 1044 1067 0.93
13 17 0.001 0.12 13.4 1.1 2 23 1074 1096 1073 1096 0.96
14 17 3.4e-05 0.0039 18.1 1.2 2 23 1104 1125 1103 1125 0.96
15 17 0.00088 0.1 13.6 2.6 1 23 1131 1154 1131 1154 0.96
16 17 6.7 7.7e+02 1.4 6.5 2 23 1161 1182 1160 1182 0.96
17 17 0.0049 0.56 11.3 1.9 1 23 1188 1210 1188 1210 0.98

Sequence Information

Coding Sequence
atgaatgttttcaacagttctacaaaatttaaacGTGTTTCTGTAAACAGTGATAAATCCCGCGATATTTCGTCGAGTATAAACAATTGCTTTCTGGTTTCAGAAGAATCAAATAATTTCGAGTGTGGAACAATTAGAAAGAACTCGAAAAAAAGTGAGAATCTTGAGGAAGCGACTCCTGGTGAATATTATGCTTCCGTTTTTAgaCAGTCAAGATTGACATCTAAGcaagaaattacaaatttagaatCTCAGGATCACACCTACGGAATAAAAATGAACTACCACTCCGCAGAGAACCAACTCGGTTCTATGACACCGACAATGTTTCACAATTATTCCTCCAATCAAATAACCGACATCAACGACCTCAGAAAAATCACCCCTAGAGTCAAGCTTTTGAATCAAGAATCGCCGACACTCCATCCAgtcaaaaaagtaaattccCCTCTCAAATTAATCGATCAGAAATCGGACTCCACAAAACAAGCACTGAGAAAATATTGTCGTACTTGCGCTGAAGTAAAATTTCCTCTCATTGATATTTTTAGCGAGAAGGGCATTCAGATGAAACTCAACCAGCAGATTCGTCACctagaaaatcttaaagaatCCGACTCCCTCTCGACTCTAATGTGCATGGATTGTATCTGTGACTTAAGAATGAGTTACACTTTCTTCATGCAGATTAAAAAAGCAGAGAACAAATTGAAGTCAATCCAGGCGAAGTTACTCGAGGCAGAGACGGCGAATTTAAAGAACCAAGTGGAAGTTCCCACAATTGATCCTCTTTTCATTCCACACgttcctgaaaatttaaatgacaACGGCCCTCGAATTTCTGCGGTTTATTCTGCTCAAGACTCCCAAAGCTGGGAACCAGATCCACTTTCTAATGTTAAAATAGAGCCTCAAACTCAGGAAGAGAACAAAATTCAGAGTGATGACGATTCCCTCGAGGAATTTGATCCTGAAGATCCTCCTTATAATCCTGAGAGTGAAGAGGAAGAGAATACGGAAGAAGAACTGGTAACTGTTCCAAATTTTGTGAAGAGtccaaaaaaattagaagtgAAGAGTGTCGTAAACAAAGAAGCAGAGAAAAGAGAGATTGAAAGCGAGAGTTTGAAGAGAAAATTCTCCGAGGAAAGAAACGAGGCTGTGGATAGATTATCGAAGTTGAAAGCGATTGGACCGAAAGATGCGAAGATTAGGAGGTTAAACGTAAATGAGgctttgaatataaaaaaggaGGAGAACGGAGTCATGTATGTTACAGTTCGAGGCACAAAACCAAATGAACTGCTTTTAGTGAAAGTAAAGAAAATGGAGAAGACTGAAAAAGGTAAAGCTGTGGGTAAGAAAGAAGTTCCGAAAGAAAAGGAGAAAGATCCGTTCACAGATCGAACTTTCGATGCAAAAGGCCAAATTATAGAAGAACAGAtagaagaatataaaaagaagaGGGAAAAAGTTCTTGGCGCTTCGGCTCAAAATGAAACACCTGAAGTGTATCGAGGGGAAGTTAGAATCAAGGCCGACGTTCTTAATATAAAGGAAAAGGAAGCCCcttctgaaatatttcatcAGGAAGAAATGGAAATTATCGAAGAAAGTCTAGATACGAAGGAAAATATAATCCAAGAAGATTTACACCAGGCTATTCTGCCCCAGGCAGTTCAGATCAAGCCAATTTTAACCAAGGAGATATTCAAGGAAGTTCCAGAGATAAAAAAGGAAGTTGTAGAGGTAAAAAGGGAAGATCCAGAGGTGAGAAAGGAGAAATCGAAGAAGAGCAAAGAACCGAAGCCGAAAGTTTACAACAACGCAGAGGAATACAATTTTCGGATTGAGACGGTGACGACCAGGTGGGAAGACAAGCAGCGAAAGGATTGGGAAGATACAAATCCCGGGATTGAAAATCCGGTGGACAGATTGAAGAGAGTCTTGGGGGAGGAGAACGAGGGGGCAAAtcttcaagaatttcttgagaATCTCCAGCAAAGAAAGATGCTACTGGAGAAATTAAATGACGAAGATATCGTTACCCTTTTCCAAGAGAGAATAAACTCTCAAAAAATTGTCTCCGAACCGGAAGAAGAAGTGAAGGCAGAAGAGCCTGAGGTTGAACTATTCGAATGTGATTTTTGCTTCATATCTTTTCCATCGAAGGAAGTTATTGAGGAGCACATGAAGATTCACGATACGAAAATTCTTCACTACTGCGAGGATTGTAACGAGGAATTTCCGGTTTTgagattgaagaaaaatcataATGTGATTTGTATCAGGAAGCTGATTTGCAAATACTGCGACTTGATGTTGGATTCGAAGGGGAAGAAGAGACAACACGAGCAAAAGCATTGTGACAGTCTCTATGGACAGATTTGCGAATATTGTGGGGAGAAGTTTAAACATCAGGGAACTTTGGATCAACATGTCAAGTCGAGACACATGGCTTTGGAGAAGGTTTTCCAGTGTCCGAAATGTCCGAAGAAGTTTGCGCTCAAGACGAAACTGAGTTTTCATTTAAAGAGCGTTCATACCTCCTTGAGGGCTTATTTGTGTGAGGATTGTGGAGCGGATTTCAAAAATCCGGCGAGCTTGAGACATCACAGAATTAGGAAGCATCAGCCGACTGGAAACAAGAAGGAATGCCCTGTTTGCAATAAGATGATTCCTTTTTATAGTCTCAGCAAACACATGCATACGCATAAGGCTTACACGATCAAATGTCCGCATTGCACTAAAATGTTCAAGAATACTTCAACGTTGAAACAGCATGTCAGAATTCACGAGGATCAGAGACAGTTTAGatgcgACACCTGCGGCGTTGGATTTAACCGAAGAGACGGCCTTCGACTCCACATGAAGGTCCACGAAAAATCGGACAGTCGAGGCCTGAAAGAGTGTTCCTGCCAAGTCTGTGGAGAAAAATTCCCGAATCACTCGATGCTTGTCATCCACCGAAATCGAGTTCACAAGGACGGGAGAAATCACACTTGTACTATTTGCAATAGATCGATGATTTCTGCCCGATCTCTGTCATGGCATTTAGCTCACATCCACAATGAAGCTCTTCCTGGAGTCGTAAAGGAAGAATTGGCTGATGGAGGAGAAACAAAAAGAGTTTGTTGCTTCCACtgcaacaaaacttttaaaactgaaatgaTTCTGCGAACGCATATCAAAAATTCTCACATGCAGAAGGAACCAGTGAAATGTTTAGATTGCGATTTGACCTTCACGAGTGACGTTAGACTCAGACATCACATGATGGTCACCCATAACAGGCTTGAAGGGACTTTGGAGTGTCCACATTGCCCGAAAAGATTTGTGAATCAGCTGAGACTGAAGACTCATATGATTTCACATTCTGAGGATCGACCGTACAAATGTGAGATTTGTGGATTTAATCTCAAGACGAAAATTCAGTTGATTAAGCATCATCAGAATCGGCACAGCGATGAAAGGCCTTTGCAGTGTCGACATTGTACTTGGAAATGTAAACAgGTTAGCGCCCTTGTTTGCCACGAAAGAACTCACACAAACGAACGTCCTTATGCCTGCAGTGTCTGCAAGCAAAGATTCAAATACCTGGgggataaaaataaacacGAGAGACGTCACGTATCTATGGGAGGTAGTGGATTTAAAAGAGTTGTTACTAGTAGAAGCGCAAAACGATCTCAACCTAAGGAAGATGGCGAGGGTGATTCTTCAATTTCTGACCAGGAACAACTGGTGGAGCAAATGGAAGAGGAAATGGATATGGAAATGGAAGAGAGACTCGTAAATTATGAGATTGATCAGGAAAATGTTAAACTTGAGGATCACGAAGATGTCACGGAAGACGATAATGAGTATTCTAATTACCAACAGGTAATTATGACTGATTACGGACAggatTATGAAGAAACTTCGAGAGAAGCTTCGGAGGCTGCTGAGGTGATAATGAGTATGGAAGATGGAAGTGTTTACACCGAAGAAGTAACAGCTGAAGATACAGAGCATATAGAGACAACACATATAATTGAAGACGAAATTATAGCGAATGAAATTCTGCAGTCGGGAACTGTTGTTCATATTGAACAGCAAGATGAGGAAGGGAAAATCCAGGTTATTCCTGTCGTTCTTTCAATTCCTGACTTAGCTACAGAAAACACTGAAGTTGATATTGCAACAGCTTCGATTATGTATAATGACGAAGAGTGTAATTAA
Protein Sequence
MNVFNSSTKFKRVSVNSDKSRDISSSINNCFLVSEESNNFECGTIRKNSKKSENLEEATPGEYYASVFRQSRLTSKQEITNLESQDHTYGIKMNYHSAENQLGSMTPTMFHNYSSNQITDINDLRKITPRVKLLNQESPTLHPVKKVNSPLKLIDQKSDSTKQALRKYCRTCAEVKFPLIDIFSEKGIQMKLNQQIRHLENLKESDSLSTLMCMDCICDLRMSYTFFMQIKKAENKLKSIQAKLLEAETANLKNQVEVPTIDPLFIPHVPENLNDNGPRISAVYSAQDSQSWEPDPLSNVKIEPQTQEENKIQSDDDSLEEFDPEDPPYNPESEEEENTEEELVTVPNFVKSPKKLEVKSVVNKEAEKREIESESLKRKFSEERNEAVDRLSKLKAIGPKDAKIRRLNVNEALNIKKEENGVMYVTVRGTKPNELLLVKVKKMEKTEKGKAVGKKEVPKEKEKDPFTDRTFDAKGQIIEEQIEEYKKKREKVLGASAQNETPEVYRGEVRIKADVLNIKEKEAPSEIFHQEEMEIIEESLDTKENIIQEDLHQAILPQAVQIKPILTKEIFKEVPEIKKEVVEVKREDPEVRKEKSKKSKEPKPKVYNNAEEYNFRIETVTTRWEDKQRKDWEDTNPGIENPVDRLKRVLGEENEGANLQEFLENLQQRKMLLEKLNDEDIVTLFQERINSQKIVSEPEEEVKAEEPEVELFECDFCFISFPSKEVIEEHMKIHDTKILHYCEDCNEEFPVLRLKKNHNVICIRKLICKYCDLMLDSKGKKRQHEQKHCDSLYGQICEYCGEKFKHQGTLDQHVKSRHMALEKVFQCPKCPKKFALKTKLSFHLKSVHTSLRAYLCEDCGADFKNPASLRHHRIRKHQPTGNKKECPVCNKMIPFYSLSKHMHTHKAYTIKCPHCTKMFKNTSTLKQHVRIHEDQRQFRCDTCGVGFNRRDGLRLHMKVHEKSDSRGLKECSCQVCGEKFPNHSMLVIHRNRVHKDGRNHTCTICNRSMISARSLSWHLAHIHNEALPGVVKEELADGGETKRVCCFHCNKTFKTEMILRTHIKNSHMQKEPVKCLDCDLTFTSDVRLRHHMMVTHNRLEGTLECPHCPKRFVNQLRLKTHMISHSEDRPYKCEICGFNLKTKIQLIKHHQNRHSDERPLQCRHCTWKCKQVSALVCHERTHTNERPYACSVCKQRFKYLGDKNKHERRHVSMGGSGFKRVVTSRSAKRSQPKEDGEGDSSISDQEQLVEQMEEEMDMEMEERLVNYEIDQENVKLEDHEDVTEDDNEYSNYQQVIMTDYGQDYEETSREASEAAEVIMSMEDGSVYTEEVTAEDTEHIETTHIIEDEIIANEILQSGTVVHIEQQDEEGKIQVIPVVLSIPDLATENTEVDIATASIMYNDEECN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01389691;
90% Identity
iTF_01391431;
80% Identity
-