Smag004390.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Synergus magnus
Gene Symbol
-
Assembly
GCA_032275165.1
Location
JAUESH010000015.1:12152461-12160750[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.6e-15 1.2e-11 44.8 0.0 9 72 236 299 230 302 0.91

Sequence Information

Coding Sequence
ATGGATAATGCCGATATTAATGGCGGGAACGCCGAGGTGGCGTGTGAAGGTTCTAACCTAGAAACCGTCGAGCAGCCGGAGAAACAATCCTCAAAAAAATCAGATGAACCGATGGAGGTAGTTCATGAAAACGCGCAGGAAGTTAATGGAGACATGCAGGATACATCGAAAACCAGCTTGTCCCCAGGGAAAAGAAATTTGCGGAAGACCAAGGCCAACTCGACAAACACCGTCGAGAGTGACGCAAAGCCCAAGATGAAGGGACGTAAACGCAAACTCTCGGAACCTGACATCAGTTCCGAGGACTCGACGGATTTCAACGGTTTTGACAGACACTGTTTCAATAACACCAATTCTAAGAATTTGGTACTTCAAAAACTTattgCTGCTGAAGTAGAATTGTCTGTCGCTCAAAAAGTAAAACGCGGCAGACCTTCACGAAAAAGTGAGGGTAATTTAGCTGGAGAGGTAGTCAAATCTATCAAAGAATCCCAATCAGACTCGATCGAACAATCAAATAATGTTGAATCTGAAGCGACTCGACTGAAATCGGATGATCTGGTTAGCAAATCGCCAGCTTCATCTGTGAATAGCAGTACACCCAATGTTCCCTTGAAATTGAGAGGGACTCGTTTAAGCCGCGGAGTTAGTCCTCCAAGCGCGGGAAAGCAAAAAACAGTCGATCTGACAAATCCTGCTTTTCAAGAACCGTTCAAACATGGCTGGAAACGCGAATTAGTTTTCAGGGGTTCTGGCCTTGATGCTAATATGAAGAAAATGTCtgatatttattatatcaCTCCAAAGGGGAAGAAAGTAAGAAGCTTCAGGGAAGTCTCTGCAAACTtgAATGCAAAAGGAAATTTAACTTTGGAGAACTTTACCTTCCATAAAGAACCGCTTGGTGTAAATGATCCCGAAAAGGAAATAATTCGAGATGCCAGAAGAGGAAAGGATTCTACTCCAATTACAAAGACTCCGAATAAAAAAGTAGCGGCTCCACCTACAAAAAGAACTGCGTCAACTAAGAAAGTTGAAGATCTTCCTCCAGAATCATCTCTAGTAGTGAAGTCTCCTCCTCCTACAAAGGCTGTTGCTAAAGCAGCCAAAACGACACCCGCGGCCCTGAAAGTTAAACCAGCGAAAAAGACTCCACTAAAAAaagagACGAAGCAGCAGCAAAAGCAGTTGGAACAACGACAACCTAGTCCTGCACTCGCGGCTTCAgaagtaaaggaaaatgagaTGCTTCCACCCCAGAAGAATTCTCCGGCTACAAGGAGGAGTCAACAGGCAGCGGAGAAGGCACTTTCACCGAAGGCAAAACGGGCTTTaaaGGCCAAAGTTCTGGAACCATGTAGCATCAGATGTTCGACCAGCATGGGCCAAATACCAAGTTTACAGTGTTGCGTCTGCCTTTGTCTTTATCACCCTGAATGTGTCGACGGCGTGGAACATGCAGGCAGTGATGATTATGTCTGTGAGAATTGTCGGCAAGACACGGAAGAAACAGTTTCTCAACTTCAACCAGTGAATTCGACCCTCACGCCACCTCCATTAATACCTATTAGTATGTTAGGCACATCAAATGCAAAATCAAAGCTTCAGGGAAACCTAGCGCCTCCGAAACTGCAAAGAATACCAAAATCTGATGGTTCAGAACCACATTTACGAATCGCTTCCAAGCATTTAAAAGCAACTTCCGTTCCGACTTTGACTGCACAGACTGATAAAAAAGAGGGAACACGGTTCGCTCAAACAGAAAATGAGTTTCTGCACAGCTTTGATGGCACAGTTCTAAAACCTGCTCAGAACATTGCTACAATGGCAGGTAAAAGATATATCATTGTAccaaaaaataatgcaatgTCAGTGCAACCTGCGATCACTATGAAGTCTGACAAAATCGGAGAGAAGCCTTCCAGCCTAAAAGTTAATTCTACAGCTGAGAATTCTAATGCAACAGAAAGTCAAAGGTCGCAAATAGCTGCAAAGGTGGAGCAAATTGATAAGATCGTTAATAATGAAGATGCTAATGAAGTTTCAATGGATCGTTCAAGAGACAATCAAAAAGATGACGCCATAGAtgattcaaaagatatttccaaagatatttcgaattcagaagaaattcCAGAATCTCTAAAAGATAGTTCAAGTACAATGGAagttgattcaaatgaattgtCTGATAGTAATCTAAACGCAGAGTTAGATGATATTAAATTGCCTGAAGTTGAACCTCCACCgaagaagaaattgaagaaattagaAGCGAAGAACCGAAGATCATCACAAAATAAATCGTTAATAAATGGTGCGACGCAGAGCAGTGATTATTCTAAAGTGGAGAATTCTAATTCAGTAGATGATCGAACTTCGACTGCGATCCTGAATATTGCGCGAGCGGGCATCAAAAAGAAACAGATTCAAGCAGAAACAGATCAAAGACAACACTTCATGGTGTCAGTTTGCGCTGGTTACCACGCATTATCTAAAATATTCCAATACCTAAAGGTTCAGGAATTATTGCGAGCTGCGAGGGTTTGTAAAATGTGGAGGGATCTTGCAGCGCATCCATCTTTGTGGAAAACTGTACGGATGAAAAATAGTCAGGTAACAGATTGGGACGGCCTGGCAGAAACATTGAAGAGGCGTGGAACACAACACttagatttaagaaaaatgttggTTTCTGGTGACTCTGACACGATGTGGAAAAAGTTCGTCTCCGTAATTCCACAAGTGACGAGTCTCGTAAAACTGGAATTATGTCGATGTTCAGAGGTTGTTGTAGAGGAAGTCATCAAAAATTGTCCACAACTGGAAGTCTTAAGTGCTTTGACGATAAAGTGCGACACCTTAAATCTAGAGTCGTTAGGAAATCTTAAGAAATGTCATGAATTAAGACTAAAGTCGGTAGGAGGAATGCAACTTCAAGGTGACCTTGCACCTTTGCAAGAATTGACGCAACTAACTCACCTGAGTCTCACCTCTATAAAAGAACTTGGCAAGAAGAAGCTTGACGTCTTGCAATCGCTAGTAAACTTGGATACCCTCGAGCTAGGAGAGTGTTCCGATTTCCCTGAGAAATTCGGTACCGAGGTTCTGGTTAAACTAAACAAATTAGAACGCTTGAGGTTTGAAAAGGGTCAAGGTTCATGTTGTACTTTCGACATCCTGGAAGGAGTTTCCAAGATGGAAACTTTAACACAGTTGGAGCTTGTTAACTTCGACGTGAAGAACGGTTTTGACAAATGCTTAGCCAACTGCACGAATATCAAAAGATTGTTGATCATACCAACATATATATCGCAGTCGGCAACATCAAATAACATGGTTTTGGCTGGTGTCATTGAACTCTCGAATAACTTGACGCATTTCGTTTGGGGCGTAACGCTCGAGTTATTGAGGGTCACTGAATTATTTGTTGACCAGTGTAATCAAATGAACAAACCTGTTAGTGGCGAATCTATACCCGTACTGAAACCAGTTCCTTGTTTAAAACTAATTCAAGATATAGAGGAGGAacctgaaagtaaaaagggAGAAGATGAAAAGCAACCAAGCGTCGCGAATCCCCAAGTTGACATTTTGCCTTTGTCTCAGTTGCAGAAGCTTTTACTAACTGCTTTGCCGAAAACAAGAGTGAAGATCCTAAAAATTCCCTTCAACGCTACTTGGCGGCAAAATATTTCAGACACGACTGCCCAATAG
Protein Sequence
MDNADINGGNAEVACEGSNLETVEQPEKQSSKKSDEPMEVVHENAQEVNGDMQDTSKTSLSPGKRNLRKTKANSTNTVESDAKPKMKGRKRKLSEPDISSEDSTDFNGFDRHCFNNTNSKNLVLQKLIAAEVELSVAQKVKRGRPSRKSEGNLAGEVVKSIKESQSDSIEQSNNVESEATRLKSDDLVSKSPASSVNSSTPNVPLKLRGTRLSRGVSPPSAGKQKTVDLTNPAFQEPFKHGWKRELVFRGSGLDANMKKMSDIYYITPKGKKVRSFREVSANLNAKGNLTLENFTFHKEPLGVNDPEKEIIRDARRGKDSTPITKTPNKKVAAPPTKRTASTKKVEDLPPESSLVVKSPPPTKAVAKAAKTTPAALKVKPAKKTPLKKETKQQQKQLEQRQPSPALAASEVKENEMLPPQKNSPATRRSQQAAEKALSPKAKRALKAKVLEPCSIRCSTSMGQIPSLQCCVCLCLYHPECVDGVEHAGSDDYVCENCRQDTEETVSQLQPVNSTLTPPPLIPISMLGTSNAKSKLQGNLAPPKLQRIPKSDGSEPHLRIASKHLKATSVPTLTAQTDKKEGTRFAQTENEFLHSFDGTVLKPAQNIATMAGKRYIIVPKNNAMSVQPAITMKSDKIGEKPSSLKVNSTAENSNATESQRSQIAAKVEQIDKIVNNEDANEVSMDRSRDNQKDDAIDDSKDISKDISNSEEIPESLKDSSSTMEVDSNELSDSNLNAELDDIKLPEVEPPPKKKLKKLEAKNRRSSQNKSLINGATQSSDYSKVENSNSVDDRTSTAILNIARAGIKKKQIQAETDQRQHFMVSVCAGYHALSKIFQYLKVQELLRAARVCKMWRDLAAHPSLWKTVRMKNSQVTDWDGLAETLKRRGTQHLDLRKMLVSGDSDTMWKKFVSVIPQVTSLVKLELCRCSEVVVEEVIKNCPQLEVLSALTIKCDTLNLESLGNLKKCHELRLKSVGGMQLQGDLAPLQELTQLTHLSLTSIKELGKKKLDVLQSLVNLDTLELGECSDFPEKFGTEVLVKLNKLERLRFEKGQGSCCTFDILEGVSKMETLTQLELVNFDVKNGFDKCLANCTNIKRLLIIPTYISQSATSNNMVLAGVIELSNNLTHFVWGVTLELLRVTELFVDQCNQMNKPVSGESIPVLKPVPCLKLIQDIEEEPESKKGEDEKQPSVANPQVDILPLSQLQKLLLTALPKTRVKILKIPFNATWRQNISDTTAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00200751;
90% Identity
iTF_01391105; iTF_01392771; iTF_01389429; iTF_01390216; iTF_01391976;
80% Identity
-