Basic Information

Insect: Synergus itoensis
Gene Symbol: Znf423
Assembly: GCA_904066005.1
Location: CAJFCP010000109.1:467853-481569[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 1.5e-05 0.0021 19.2 1.3 1 23 97 119 97 119 0.98

2 20 0.49 67 5.0 3.9 1 23 125 147 125 147 0.97

3 20 1.1e-06 0.00015 22.8 4.1 1 23 153 175 153 175 0.99

4 20 0.00013 0.017 16.3 0.4 1 23 181 203 181 203 0.98

5 20 9.4e-05 0.013 16.7 0.7 1 23 349 372 349 372 0.96

6 20 0.043 5.8 8.3 0.0 2 23 382 404 381 404 0.89

7 20 0.21 29 6.2 0.1 3 23 466 486 465 486 0.97

8 20 0.014 1.9 9.9 0.3 2 23 499 520 498 520 0.97

9 20 0.0016 0.22 12.8 0.7 1 23 529 552 529 552 0.93

10 20 0.17 23 6.5 0.2 1 23 557 580 557 580 0.89

11 20 0.6 81 4.7 2.0 2 23 653 674 653 674 0.96

12 20 0.0058 0.79 11.1 0.2 1 23 679 702 679 703 0.94

13 20 3.4 4.7e+02 2.4 0.1 2 23 782 805 781 805 0.81

14 20 5.2e-05 0.007 17.5 1.0 2 23 821 843 820 843 0.96

15 20 0.04 5.4 8.4 0.4 1 23 852 875 852 875 0.91

16 20 0.025 3.4 9.1 0.0 2 22 1066 1086 1066 1088 0.89

17 20 0.19 26 6.3 0.3 1 23 1094 1117 1094 1117 0.95

18 20 4.6 6.3e+02 1.9 0.4 2 23 1130 1151 1129 1151 0.92

19 20 0.2 27 6.3 0.1 2 23 1160 1182 1159 1182 0.94

20 20 0.044 6 8.3 2.6 1 23 1189 1212 1189 1212 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	1.5e-05	0.0021	19.2	1.3	1	23	97	119	97	119	0.98
2	20	0.49	67	5.0	3.9	1	23	125	147	125	147	0.97
3	20	1.1e-06	0.00015	22.8	4.1	1	23	153	175	153	175	0.99
4	20	0.00013	0.017	16.3	0.4	1	23	181	203	181	203	0.98
5	20	9.4e-05	0.013	16.7	0.7	1	23	349	372	349	372	0.96
6	20	0.043	5.8	8.3	0.0	2	23	382	404	381	404	0.89
7	20	0.21	29	6.2	0.1	3	23	466	486	465	486	0.97
8	20	0.014	1.9	9.9	0.3	2	23	499	520	498	520	0.97
9	20	0.0016	0.22	12.8	0.7	1	23	529	552	529	552	0.93
10	20	0.17	23	6.5	0.2	1	23	557	580	557	580	0.89
11	20	0.6	81	4.7	2.0	2	23	653	674	653	674	0.96
12	20	0.0058	0.79	11.1	0.2	1	23	679	702	679	703	0.94
13	20	3.4	4.7e+02	2.4	0.1	2	23	782	805	781	805	0.81
14	20	5.2e-05	0.007	17.5	1.0	2	23	821	843	820	843	0.96
15	20	0.04	5.4	8.4	0.4	1	23	852	875	852	875	0.91
16	20	0.025	3.4	9.1	0.0	2	22	1066	1086	1066	1088	0.89
17	20	0.19	26	6.3	0.3	1	23	1094	1117	1094	1117	0.95
18	20	4.6	6.3e+02	1.9	0.4	2	23	1130	1151	1129	1151	0.92
19	20	0.2	27	6.3	0.1	2	23	1160	1182	1159	1182	0.94
20	20	0.044	6	8.3	2.6	1	23	1189	1212	1189	1212	0.94

Sequence Information

Coding Sequence: ATGCTGTTCAAAGGTAACAGTTCGAGATTAGAACTGTTAATTGGAAAAATTCAGGCGCATAAGGAACCTCAGTCACCACCAAGAGACGAAAAGTGCCTCTCTAAGCCTAAAGAGGCCCTCGGAACCGGAAGTTCGTCCTGGCACAGTGAAGACGGAAGGCCGACTTCCCGAAAGGGAGAAGAAACACCATCTTCTTGCGCAACTCCTACATCCGCCAGTTTTCCTTCGGAACCGGAAGTGGAAACTGATATTGGTCCCACAGCCGATGGAAGTAATCCTGCCGCTCCATACCCTTGCCAATTTTGTGACCGAATGTTCCCCAGGTTAAGCTATCTCAAAAAGCACGAACAGAGCCATGGTGACCAGATGCCCTACAGGTGCAGTTGGTGTGCAAGATTGTTTAAACATAAAAGAAGTAGAGATCGTCATGTGAAATTACACACCGGCGACAGGAGATATCGATGCTCGCATTGCGAGGCTGCTTTCTCGAGAAGTGACCACCTGAAGATCCATATGAAGACTCATGATACTCAAAAGCCTTTCCAATGCACCTCATGTTCCCGAGGCTACAACACAGCCGCAGCCTTGACATCCCACATGCAGAGTCACAAAAGACACCAAAACTCCCAAGGATCCAAACTAGAGATGGATTTCGGACGAAGGAGTGTTTCCTCTCACAGTACAGCATCACCTCCCATTCCAAATTCACCTTCCCCAAGTTTAAATTTAACCCTCAGCCAAAAAAAGTCCCAGGCTAGTGTATCCAACATCCCAATCCTATCATCACCTTTAAAACTCGCCTGCATGTACTGTACTCGAGATTCCTTCACTAGCATGCAGCAACTTCAACTTCACGTCCACACAATGCACCAAGCAATCCTGAGTGGAGAAAACCTGATGCCATCACCAGGTCAAACTCTGGAACTATCAACCCACTCTAGAGAAAAATCTGATCGTCAAGACAGAACCTTGAGAGAAGATCTGTACGACAAGAAGTTTTCAGAAGTTAGACCCTTCGAAGAGAAAGACATCTTCGATTCAGGATTTTCCTGTGGACAATGTACCATGAAGTTTTCTTCTTCAAGTTCTCTCAGAGATCATCTAGTTACGATCCATCGATCTAGTGCTTTCGGATCACTGATGGTATGTCCAATCTGTGGAATTCCCTGTTCCTCAGCAGCTGCCTATGCAGAACACTATGTTCTTCAACATTGTGAAAATAGAGTATCAGCTGAAGGTCGAGAATACACTGATCCGAAGATAAATGGATCCTACGACTCTAAAGAATTGAGAGCAGCTGACCGAGGAAAAATATCAAAGGATCTGAACTCTGAACCTGCTGATCTAACTAAACATTCGAAGACTAGTGAAAATTACTCGGCAGGGACTTTGCTCTGTGGACAATGTGGAGCAGCTTTGAAAGACTTCGAATCCTTCAGAGAACACCTGGCAAGGCATCTTCAAGCTGATCAGAGAAGTGAGATTTCAAGAAACCAGTGTCCAAAGTGTGAAGCTTCTTTTCAGGAGAGGGATGATATGATGGTCCATTTAACGAAACATTTTTTGGGTCAAGTGACCAAGGAATACGCCTGCAGTGCCTGCAAGAAATTTTATCCCCATCCTGATCTTCTTCAAAGGCACTTGCTTGATTCTCATGCTCATCATCTTTACAGGTGTGCCCTTTGTAGAGAGACTTTTGATTCCAGGGTAGCGATCCAAGTTCATTTTGTTGTGAAACACAGTCAAGAATGCCGGATATACAGATGTAATGTCTGTTCTGGGTCAAACAATGAAAACTCTCCTGGAAACACTCCTGGGGAAAACAGGAACTTCTTCAGAAGCGAAGCTGAAATGGCGAACCACGTTAAAACTGTACATGCTCCTCCGTCCATTGTAAACGAAAGTCCTGTTCCTAGGAGTCCTGCATCAACTCCAGGCATGACGAACACAAACCCAAGGTGTGTTTTTTGTGGAGTTTGCTGTTCCTCCGACTTGGATCTGCAGCTCCACTTGGCAAGCCACTCTACAAGTCTGTACCGATGTCCCATTTGTCGAGAGGGCTTTGCTGTTGAGTTTCTTTTGGATAGGCATATTGCTCAGACTCATCATGCCAATGATCACCCGAGCACTCCAAGAAGTCACACTAGGGAAAATGGAAGGATACATCGACCTTCCAGGTCTCAGGAAGATGCCATCAGTTTAGAAGTGAGGGAACAGAGGGATCAGAGAGAACCGAGGGATCAGAGGTCTCTAAAACGAGGAAGATCCCCTGCTTCCAGTAATAACAATTCTTTAAACCAAAGAGACAATAACAACAAGAGACAGAATTTCGGAACTGCCCAGCAATGTGAACTTTGTGAAAGAGGAGAATTCGCCAACGAAGCTGAACTGCAAGCTCATAAAAAATTGGCTCACACTCCTGCAAAGGTTTCAGGAAAATCTTTATCAGCTTTGAGCATGACTTGTGCTTATTGTGGGGAGGTTTGTCGATCAAGAAGTGAATTAGAGTCACATACAAGAATACAACATGCGACTAATGATCATGGAGGTCGACACAAGTGCAACATCTGCGATGAAGTTTGTCCCTCTGGAGCAGCTTTAGCTGAACATAAACTAGAGAAACATTGCAAAATTCAGCTGAGTGATGTTTGCATTGTCTGCAGAGGCAATTTATCGTCTGAGTCCCACTTTTTGGAACATGTTCAGAGACATAGCTTAGAGAGTGTTGATCCCCAACAGAGGCTAGACAGTTCACTGCCACAGCTTCCTGCACCTTGTGTGGTTTGTAGACAAACTTTGATCACTGATTTTGAATGTAGGCTTCATGCGAGGCATCATTTGAGATCTAGTGGAGGTTCTCAGAAGTCTGACTCGAGTCCGAGTCCTAATCAGAAGACTCAGAGTCACAGTTGCTGTCTTTGTCTCAGGGAGTTTAACGGAGAGGAGTTTGTTAGTTTGCCTTCAAATCATTCCAGTAGTGGTAGTCAAACATTAAAAGTTTGTAGAGATTGTTATGTGAGGCATTCGCAAGGTCTTCCAATTTTGAACTCACCTTATGAACATGCCAGGACTAGTCAAAGTGAGTTGTGGATGAAGGAGTCACATTGGGATGGATCTAGGGAGAGATTGGATGCTGAAAGGAACTTTAAGGTAGAAGAGAGAAGTTCTAATTATGGAGGATCGAATGATGGGAGAAGGTGTGAAGAATGTGGGGTGAAGTTTGAAGATCCAGAGGAGGCAGAAAAACATAGGGTTGCTGAACATGAGAGGCCTGGGACTTATACTTGTATTCAGTGCCAGATATCTTTTCCAACTGAGGCTAAAATACAGCAACACGTTAAGAAGGAACATCTTGAATCTACTGGGAAAACTTCTCTGGAAGCTTTGCGTTGTCATCTTTGTTTATTTGATGCTAATAGTCCACTCCAGCTTCAGAGTCATCTTATAGAACACACCTTTGCTGGATGCACTGCTCTCAGTTGCTATATTTGTCAAGCCTTATTTACAGCTCCCATTGGACTTCAGAATCACATGCTTCAGCAACATGGTCTTGGCGCTCGACCTTACGATTGCAGCCACTGTGACTTGAAGTTTTTCTTTAGGGCTGAACTTGATCATCACGTCGCTGTTTTTCACTCTACGCGAGAAAATATTTCTTCTCCTCAAGGCAGAAAGGTCCAAAACGATATTCAAGATTCAGACAAACGAACTGAAGCTTCTGATAAAGTGACCATCAAAGAAGAAGTTCGACAAAGCAATGAAGATGAAGATGAAGATGTCAATGTGAATATTAATAATAAATCCGAAAAACAGGAAAAAAGCTCTCGAAATCTCGAATCTTCATCTGAAGAAATCCGAACCGAGTGTCCAAAATCTGAGTTGGAATAG
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPQSPPRDEKCLSKPKEALGTGSSSWHSEDGRPTSRKGEETPSSCATPTSASFPSEPEVETDIGPTADGSNPAAPYPCQFCDRMFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDTQKPFQCTSCSRGYNTAAALTSHMQSHKRHQNSQGSKLEMDFGRRSVSSHSTASPPIPNSPSPSLNLTLSQKKSQASVSNIPILSSPLKLACMYCTRDSFTSMQQLQLHVHTMHQAILSGENLMPSPGQTLELSTHSREKSDRQDRTLREDLYDKKFSEVRPFEEKDIFDSGFSCGQCTMKFSSSSSLRDHLVTIHRSSAFGSLMVCPICGIPCSSAAAYAEHYVLQHCENRVSAEGREYTDPKINGSYDSKELRAADRGKISKDLNSEPADLTKHSKTSENYSAGTLLCGQCGAALKDFESFREHLARHLQADQRSEISRNQCPKCEASFQERDDMMVHLTKHFLGQVTKEYACSACKKFYPHPDLLQRHLLDSHAHHLYRCALCRETFDSRVAIQVHFVVKHSQECRIYRCNVCSGSNNENSPGNTPGENRNFFRSEAEMANHVKTVHAPPSIVNESPVPRSPASTPGMTNTNPRCVFCGVCCSSDLDLQLHLASHSTSLYRCPICREGFAVEFLLDRHIAQTHHANDHPSTPRSHTRENGRIHRPSRSQEDAISLEVREQRDQREPRDQRSLKRGRSPASSNNNSLNQRDNNNKRQNFGTAQQCELCERGEFANEAELQAHKKLAHTPAKVSGKSLSALSMTCAYCGEVCRSRSELESHTRIQHATNDHGGRHKCNICDEVCPSGAALAEHKLEKHCKIQLSDVCIVCRGNLSSESHFLEHVQRHSLESVDPQQRLDSSLPQLPAPCVVCRQTLITDFECRLHARHHLRSSGGSQKSDSSPSPNQKTQSHSCCLCLREFNGEEFVSLPSNHSSSGSQTLKVCRDCYVRHSQGLPILNSPYEHARTSQSELWMKESHWDGSRERLDAERNFKVEERSSNYGGSNDGRRCEECGVKFEDPEEAEKHRVAEHERPGTYTCIQCQISFPTEAKIQQHVKKEHLESTGKTSLEALRCHLCLFDANSPLQLQSHLIEHTFAGCTALSCYICQALFTAPIGLQNHMLQQHGLGARPYDCSHCDLKFFFRAELDHHVAVFHSTRENISSPQGRKVQNDIQDSDKRTEASDKVTIKEEVRQSNEDEDEDVNVNINNKSEKQEKSSRNLESSSEEIRTECPKSELE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00980419;
90% Identity: iTF_00980419;
80% Identity: -