Sito005914.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Synergus itoensis
Gene Symbol
mecom-b
Assembly
GCA_904066005.1
Location
CAJFCP010000050.1:3622319-3641067[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.018 2.4 9.5 0.4 2 23 207 229 206 229 0.94
2 8 8.3e-05 0.011 16.9 1.0 2 23 266 292 265 293 0.87
3 8 4.6e-06 0.00062 20.8 2.6 1 23 299 321 299 321 0.95
4 8 0.0005 0.068 14.4 7.2 1 23 327 349 327 349 0.98
5 8 6.6e-05 0.009 17.2 3.5 2 21 357 376 356 377 0.94
6 8 4.4e-09 6e-07 30.3 1.3 1 23 732 754 732 754 0.99
7 8 3.4e-07 4.7e-05 24.4 1.7 1 23 760 783 760 783 0.97
8 8 2.8e-06 0.00038 21.5 3.4 1 23 789 811 789 811 0.99

Sequence Information

Coding Sequence
ATGGCCAAAGTGGCGACGAACGTCATCATCACCCTGAGCCCCATCCTGACTGGAGTCCTTCGCTCTTTTGTCGCATATAGCATTTCAGCAAAACTGCAGAGAGAAGAAGACTCGGGTGCCCCAGCAGTGAAACCTTTCGACGTATCCGAATGGTTCGGTTTTGTTGGAGGTGTGAGGTTACAAAGGAAGCGATCATCTGTTTTGTCGCCGATGTCCTTACATTTCAGACAGACCGATGAGGATCACTCGACCGCATGTCATCCTGATCATCCGGAAAGTTCCTTCCTTCATCCATTCAAAAATGTTCGAGTTCCAGGAAGTGGAGCAAGGGGATGGTTCGATGCCTCCCATGAATCGAGTAATTGGCTCAAGTACATTCGAAGCACAGCGAGTCCACATACAGTCAACATGCGACATGTTCTCATCGGAGGAGAGGTCGTGTACGAGACAGTACGAGAAGTGGCAGCCGGTGAAGAGTTATTGTTAGGACTTCGAGAACCTCTTCAGCTTCCAGACTTGTTGGGAGAAAACACGACCGAGGACAGGAACGACCGAGAGACCGCTTCTCAACATAGTGAAACAATAGATGAAAACAGAGAAGAAGAAGATGGGGATATAAAATGTACAGTCTGCGACAAACCGTTCCAGGATATTGACGTATTGGACAATCACCTTGTAACCTGTCACCGCTACCCAGCAGACCAGCATCGCTGTGAAAGTTGTTCAAGTGGCTACGCCTGGCGACCATTACTCGTCCGTCATCGTGCAATCGTCCACGGAGATTTTCGAAAATACCTCTGCGAAAATTGTCCAAAGGTTGAAACTTCGCAGGTTTTCACCGATCCATCGAATCTTCAGCGGCACATCAGGTCCCATCACGTCGGAGCCAGAAGTCACGCTTGCACCGAATGTGGAAAAACCTTTGCAACAAGTTCTGGACTCAAACAACATACTCACATCCACAGCAGCGTAAAGCCATTCCATTGTGAAGTTTGCCTAAAGTCTTACACGCAGTTTTCAAATCTATGTCGTCACAAACGGATGCACGCAGTTTGCCGCACTCCAAGCAAATGCCATAAGTGTGGCCAGTCCTTCAATACTTCCACATCCCTCACCAAACACAAGAAATATTGCGACTCGACACCACCTAGATTAGGAGCGATGCCTCAGCTCCCCACATCCACGACAAGTTCGTTTTTGGTCTATCCAAGAACACCAGTTTCCCTACCTGGGGGACTTCCATTTTATCCATCAAATCTCATGAGCCACTATCATGGAATATTTCCCAGTGCGCCCAACTTCCTCAATTCGCCACTTCTGTATCAGCATCAGAAAGTCGAGGAAGCTGAGAAGCGGAGTGAGAGTCCCAAGAAGGAACGATTCACCCCACCCAGAGTTCCTCAACAGAGCAAGATCTCTCCCTACACTGCCGAAGAAGCAACCTCGACATTCAGACCTTCGCCAGCAAGACCTCTTCAGCCGACTCCCGAACCTCTGCAGGAGGAGAGACTCGCGGATCTCTTGAAAATCGAGAACAAGGAACAGAGTCTGAAAGAAGAGAAACTTGAAGAAGCAGATCAACCCCTGGATCTCAGTCTACAGAAAAGGAAGAGGACGACCACTTCTAATGACTTCAGAGTCTTCACACCTAAAAAGACTTCCTGTTCCCCGATTCCCGACGCAGAAGAAGAACCTCTGAAGATCAGGAAAAGGGAAAGAACCGACTCGGACGATTCTAGAGATTCTACACCTAAAATAAAAGAACTCTCTCATGAAGAACCACATATTGATCTCAAGAAAGAAGTAATAACTCCTCCTCCCCTTCCTCTGAGAACTCCTCTCGCTTCCGATCAGCCGAATCCACCACATATGGCTTATCACAGACCAATTCATCCCATGTTTCTAGAAGCTATGTACCGCCAACCAGCTGGAAATTTCGCGGGATTTTCGGGGGCACCTCCAAATGGTGCGGAATCTCGGCTCATGCCTCCACTTCCTCCTTTTGGTCCGCCGCGTGGGTTTCCTTTTTTAAGACCACTCATGAACGGTTTCAATAGTGGTCGACCAAGTTATGACCTCCTACCGACAACACCCACCTTAGGACCTTTTCCTGGAGTGAAGCCCTATCAAGATGCTGTCATGCCTCATCATCACAATCATCATCATCATCATCACGGGAAGATGAAGGATCGCTACACCTGCAAGTTCTGTGGGAAAGTCTTTCCGAGATCAGCGAATCTAACGAGACACTTGAGAACTCACACTGGAGAACAGCCCTACAAATGCAAATACTGCGAAAGGTCTTTCAGTATATCTAGCAATCTTCAAAGACATGTCAGAAATATTCACGACAAGCAAAGACCTTTCAAGTGTCCTCTATGTGATCGTTGCTTCGGACAACAGACGAATTTGGACCGACACTTGAAGAAGCATGAAGCTGATGACGGAAGTGGTGTTGTTGCTGTGGCTGACTCACCAGGAAGTAGTAATGAAAACGAAAGGGAGGACACTTGTTTTGACGAGATTAGATCTTTTATGGGGAAAATTACCTATGGAGGTGAAGGTTACGGACTTCCTTATCATCCCGCATATTTGCCAGGGAGGCTGCATGAAATGCACGAACCAAAAGGTGAATTTGACGATGAAGAGGACAGCGAGGGGGCAGTTTCTCCAGTTGAAGAAGGCGATGCTTTGTCTCCAATTCCAAAGGAGATTGATGCACCTGAATTTGATCTTAAGTTAAGAAACAAGCAAAAGATGCTCAATAATAATACGGCTGAGCCGGTGATCGAGGTTTCCACGTAG
Protein Sequence
MAKVATNVIITLSPILTGVLRSFVAYSISAKLQREEDSGAPAVKPFDVSEWFGFVGGVRLQRKRSSVLSPMSLHFRQTDEDHSTACHPDHPESSFLHPFKNVRVPGSGARGWFDASHESSNWLKYIRSTASPHTVNMRHVLIGGEVVYETVREVAAGEELLLGLREPLQLPDLLGENTTEDRNDRETASQHSETIDENREEEDGDIKCTVCDKPFQDIDVLDNHLVTCHRYPADQHRCESCSSGYAWRPLLVRHRAIVHGDFRKYLCENCPKVETSQVFTDPSNLQRHIRSHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFHCEVCLKSYTQFSNLCRHKRMHAVCRTPSKCHKCGQSFNTSTSLTKHKKYCDSTPPRLGAMPQLPTSTTSSFLVYPRTPVSLPGGLPFYPSNLMSHYHGIFPSAPNFLNSPLLYQHQKVEEAEKRSESPKKERFTPPRVPQQSKISPYTAEEATSTFRPSPARPLQPTPEPLQEERLADLLKIENKEQSLKEEKLEEADQPLDLSLQKRKRTTTSNDFRVFTPKKTSCSPIPDAEEEPLKIRKRERTDSDDSRDSTPKIKELSHEEPHIDLKKEVITPPPLPLRTPLASDQPNPPHMAYHRPIHPMFLEAMYRQPAGNFAGFSGAPPNGAESRLMPPLPPFGPPRGFPFLRPLMNGFNSGRPSYDLLPTTPTLGPFPGVKPYQDAVMPHHHNHHHHHHGKMKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCDRCFGQQTNLDRHLKKHEADDGSGVVAVADSPGSSNENEREDTCFDEIRSFMGKITYGGEGYGLPYHPAYLPGRLHEMHEPKGEFDDEEDSEGAVSPVEEGDALSPIPKEIDAPEFDLKLRNKQKMLNNNTAEPVIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01393755;
90% Identity
iTF_01392242;
80% Identity
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