Basic Information

Insect: Synergus itoensis
Gene Symbol: topi
Assembly: GCA_904066005.1
Location: CAJFCP010012934.1:10265-12010[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.089 12 7.3 2.5 1 23 76 98 76 98 0.97

2 15 0.0096 1.3 10.4 0.4 2 21 134 153 133 154 0.93

3 15 4.6e-06 0.00062 20.8 2.0 1 23 161 183 161 183 0.96

4 15 3.4e-07 4.6e-05 24.4 1.2 1 23 189 211 189 211 0.97

5 15 0.0016 0.22 12.8 0.3 2 23 223 244 222 244 0.95

6 15 4.9 6.7e+02 1.9 3.8 1 23 260 282 260 283 0.93

7 15 8.5 1.2e+03 1.1 1.1 1 12 288 302 288 304 0.77

8 15 1.3 1.7e+02 3.7 4.6 1 22 320 341 320 344 0.89

9 15 0.00093 0.13 13.6 0.3 1 23 357 379 357 379 0.96

10 15 0.00018 0.025 15.8 0.1 1 23 383 405 383 405 0.95

11 15 1.6e-06 0.00021 22.3 3.1 1 23 411 433 411 433 0.98

12 15 0.00012 0.016 16.4 0.5 1 23 439 462 439 462 0.97

13 15 0.038 5.2 8.5 0.7 1 23 468 490 468 490 0.89

14 15 2.1e-07 2.9e-05 25.0 1.1 1 23 496 518 496 518 0.99

15 15 1.2e-05 0.0016 19.6 5.0 1 23 524 547 524 547 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.089	12	7.3	2.5	1	23	76	98	76	98	0.97
2	15	0.0096	1.3	10.4	0.4	2	21	134	153	133	154	0.93
3	15	4.6e-06	0.00062	20.8	2.0	1	23	161	183	161	183	0.96
4	15	3.4e-07	4.6e-05	24.4	1.2	1	23	189	211	189	211	0.97
5	15	0.0016	0.22	12.8	0.3	2	23	223	244	222	244	0.95
6	15	4.9	6.7e+02	1.9	3.8	1	23	260	282	260	283	0.93
7	15	8.5	1.2e+03	1.1	1.1	1	12	288	302	288	304	0.77
8	15	1.3	1.7e+02	3.7	4.6	1	22	320	341	320	344	0.89
9	15	0.00093	0.13	13.6	0.3	1	23	357	379	357	379	0.96
10	15	0.00018	0.025	15.8	0.1	1	23	383	405	383	405	0.95
11	15	1.6e-06	0.00021	22.3	3.1	1	23	411	433	411	433	0.98
12	15	0.00012	0.016	16.4	0.5	1	23	439	462	439	462	0.97
13	15	0.038	5.2	8.5	0.7	1	23	468	490	468	490	0.89
14	15	2.1e-07	2.9e-05	25.0	1.1	1	23	496	518	496	518	0.99
15	15	1.2e-05	0.0016	19.6	5.0	1	23	524	547	524	547	0.96

Sequence Information

Coding Sequence: ATGAGTGATGAAGATACAAAAATGGAAGTTCTTAATGATTCTTTAATTTGGGAATTACCGCTTAAATTCTTGAAGGAAACCTCTGGAAGTTCTTCAATAACTCTCCAGTGTCTAGAAAGCACCGAAAAAAGTTTTAAATGTGGAGCTTGTATGAATCTTTACCACACGAAGGAAATGCTCGAGACTCACAAGTGTAAATCTCCAATTCAAAATAATTCCAAACCCTACGTCTGCACTCTCTGCGAAGCAAAATTCAACTTCGAGGAACATCTAAACTTCCACCTCAAATACCATAATGGATCAAAAGCTCTCTACTGTGAAATTTGCAAAATAAATTTTGGAAAAGAGCTTAAATTCTTTTTCCATTATAAAATATATCATTCTAAAGAGAAGGTTGTATCCTGTCTTCAATGTGGAAGACTTTTTCAGAAACAGGAAGAGCTTAAGATTCATATTTGTGTTGATGGAAAAGCAAAGCCTCACGCCTGTGAGGTTTGCAATAAAAGATTTTCTGATGGTTACACTTTGAAGAGACATCTTATGACTCATCTTCCAGAAAAACCTTATAAATGCGATGAATGTTCGAAGAGTTTTACCCAAAAATCAAGATTGAATAAACATATCGCTGGTCATGAAATTGTGATGGAAAGTTCTCAGAATCTTTGGAAGTGTATGGATTGTGGAAAAGTTTTTGGTACGTTCGAAGAAGCTGAGAAACATTTTCAGAATCATGATCAAAAGATTCTGATTGTTGAGGAAGTTTCGGCGACGAAGGTATACCAGTGCGAATTTTGTAACAGTTATTTTATGGAGAGGGAACGAATGAAAATTCATCGCAGTCAACATCATTTGGAAAAGGCTTATGAGTGTCAGGATTGCAGGATGGTTCATAAATGTTTTTCTCAAGCTGTCATGGATTGGAAGCAACATCCGAAAGCTTTTAAGGTTCAGGTCCTCTTCATCTGCGAAATCTGCAACACGGAAGTAAAACACCTACACGTCCTCTACAAGCACTACCACAAAAGACTTCACTATCTCCCTCGATCAACGGAATACGGAACCGAAAAATTCGCCTGTGAACTCTGTGGATCAGTTTTTCAAGATCTCGACGAATTCAAAAATCACAAGAGGGACCATTGTTCAAAATTCCTCTGCGATATCTGTGGAAGTTCTTTACCTTCCGCAAGTTCCTTAAATGCTCATAAAAGACGTCACAGTGGACTTAAGCCTTACGTTTGTAATATTTGTGGAAAAAGTTACACGCAATCGAGTCATATGTGGACTCACAAAAGATTTCATATGGGGATCAAACCTTATGCTTGTGAATACTGCGATCAAAAATTCACAATCAAACCCGATCTAGCTGATCATACGAGGAAAAAACACACAAGGGAAAGGCCTTTTAAATGCGACGTTTGCAATAAAGCTTTTCTCACTGGATCAGTTTTTTATCAGCATAGACTTATTCACACAGGCGATAGAAGATATAAATGTAGTTACTGCCAAAAGGCTTTCACAAGGACTGAGGCTTTGAATAATCATATTAAAATTCATACGGGAGAAAAACCTCATGCTTGTGATGTTTGCGGAAGATGTTTTAGACAGAAAGGAGATATGAGAAAACATAGGAAAACTCAGCATACTGAAAAAGGTGTAGAATTGTAG
Protein Sequence: MSDEDTKMEVLNDSLIWELPLKFLKETSGSSSITLQCLESTEKSFKCGACMNLYHTKEMLETHKCKSPIQNNSKPYVCTLCEAKFNFEEHLNFHLKYHNGSKALYCEICKINFGKELKFFFHYKIYHSKEKVVSCLQCGRLFQKQEELKIHICVDGKAKPHACEVCNKRFSDGYTLKRHLMTHLPEKPYKCDECSKSFTQKSRLNKHIAGHEIVMESSQNLWKCMDCGKVFGTFEEAEKHFQNHDQKILIVEEVSATKVYQCEFCNSYFMERERMKIHRSQHHLEKAYECQDCRMVHKCFSQAVMDWKQHPKAFKVQVLFICEICNTEVKHLHVLYKHYHKRLHYLPRSTEYGTEKFACELCGSVFQDLDEFKNHKRDHCSKFLCDICGSSLPSASSLNAHKRRHSGLKPYVCNICGKSYTQSSHMWTHKRFHMGIKPYACEYCDQKFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHTGDRRYKCSYCQKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRKTQHTEKGVEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01390549;
90% Identity: iTF_01390549; iTF_01394590;
80% Identity: -