Sgif028957.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Synergus gifuensis
Gene Symbol
BTBD2
Assembly
GCA_904066015.1
Location
CAJFCO010000146.1:1176249-1179705[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 6.7e-24 2.5e-21 76.7 0.0 20 109 124 211 118 212 0.94
2 2 1.3 4.7e+02 1.8 0.0 80 109 214 243 210 244 0.84

Sequence Information

Coding Sequence
ATGTCGGATGGGCCAGCGAATGACGTTTCAGCTGCAACTTCCAGATTACATACTTTGCGAATTTTTCGTGAAGAAGCGGAAGAGGCTAGAAACATGGAAAACGAAGGCGAAGCTTCTGCAACAGATTCTCCTCAGAATATGCAACCTGCAGGAAATATTTTGATGTCACGGGCTCGACGTGCTCTTACTTTTTCTGCTGACGAAGAACCAAGTACTTCTTTTGCTAATCGACCTGGAGAAGCTTCTTCTTCGAATGCTGAAGAAAGGCCTTTGGGGAATGCAAGCAACGCCCAGCCGGTGTCAAGATCGCAAAATGCAGTCTTCGAAAATGAATTAGCCCGCCGACCTCCAGCGACTTATAACTGGCAACAGCAATCGATTCCTGCACATAAGCTAGTCTTGTCTTCCGGAAGTGCCGTTTTCGACGCTATGTTCAACGGAACTTTGGCCACAGCTTCAGTTGAAATTGAAGTTCCTGATGTTGAGCCTGCAACTTTCCTTGCTGTTCTTTTATTTCTCTACACGGACGAAATTCAAATTGATCCTGAAACGGTCATGACCACACTTTACACAGCAAAGAAATACGCAGTTTCGCCTCTGGAGAAGCATTGTGTCGATTTTTTGAGGAACAACTTGACGACTGATAATGCCTGTTTGCTCCTGGCTCAGGCCCGTTTGTTCGATGAGCCGCAATTGGCCGATGTTTGTTTGGATACGATTGATAAATCCACCACTGAGGCACTTAATGCGGACGGATTCACGGATATTGATATCGAAACACTGATCGTTGTTTTGGAAAGAGACACGCTCAGAGTGAGGGAGTCAAAAATTTTCCAGGCTGTTGTCAGGTGGTCTGAGGCCGAATGTGTGAGGCAACAACTTCCGGTGACTCCAGATAATCAGAGATCGGTTTTGGGAAAAGCTCTTTCCCTTGTACGATTTCCTTTAATGTCAATGGAGGAATTTGCGAGTGGAGCAGCGCAAGCTGGTCTTCTTACGGATAAGGAGGTCGTGTCGTTATTTTTGTACTTTATCCTCAATCCAAAACCGAAAGTCGGATTCGAAGCAATGCCCCGATGTCGAATGATGGGGAAGGAGCAAACAGTTTGCAGATTTCAGCAGACTGAAAGCAGATGGGGATATAATGGAACGAGCGATCGAATCAGATTCTTAGTCGATAGAAGAATCTTTTTAGTCGGCTATGGGGTTTACGGAAGCATAAAAGAGAATGGCGCTGGAGAATACGACGCCGTTATCGAGTTAATTCATACAGCAACTGGAAAAGTGATAGCCACGAATTCTACCAGTTTCAGTAGCGATGGCTCCGATTATACTTATCGACTAATGTTTAAAGAGCCGGTAGAAATATTGCCCAACACGGTTTACACAGCCTCTGCCAAATTTGAAGGTCCGGATTCATATTACGGCCTCAAAGGACTTCGAAAAGTGACCGTCGATTGCGATTCGGGACAGAGTAAAGTCAAATTCCAGTTTAACTTCGAGGCTGGAGACAACAATGGCACTTGTGTTGAAATCGGACAAATTCCTGAGCTTATATTTTATACCCTGTAA
Protein Sequence
MSDGPANDVSAATSRLHTLRIFREEAEEARNMENEGEASATDSPQNMQPAGNILMSRARRALTFSADEEPSTSFANRPGEASSSNAEERPLGNASNAQPVSRSQNAVFENELARRPPATYNWQQQSIPAHKLVLSSGSAVFDAMFNGTLATASVEIEVPDVEPATFLAVLLFLYTDEIQIDPETVMTTLYTAKKYAVSPLEKHCVDFLRNNLTTDNACLLLAQARLFDEPQLADVCLDTIDKSTTEALNADGFTDIDIETLIVVLERDTLRVRESKIFQAVVRWSEAECVRQQLPVTPDNQRSVLGKALSLVRFPLMSMEEFASGAAQAGLLTDKEVVSLFLYFILNPKPKVGFEAMPRCRMMGKEQTVCRFQQTESRWGYNGTSDRIRFLVDRRIFLVGYGVYGSIKENGAGEYDAVIELIHTATGKVIATNSTSFSSDGSDYTYRLMFKEPVEILPNTVYTASAKFEGPDSYYGLKGLRKVTVDCDSGQSKVKFQFNFEAGDNNGTCVEIGQIPELIFYTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01391329; iTF_00460934; iTF_00200909; iTF_00089702; iTF_00011283; iTF_00676881; iTF_00879842; iTF_00980274; iTF_00883146; iTF_00881396; iTF_00882271; iTF_00880594; iTF_01392894; iTF_01393662; iTF_01394468; iTF_01392136; iTF_01389578;
90% Identity
iTF_00676881;
80% Identity
-