Basic Information

Gene Symbol
ECU06_1150
Assembly
GCA_032164275.1
Location
JAUEJJ010000021.1:16796153-16801500[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.00011 0.013 16.5 0.1 2 23 262 283 261 283 0.97
2 22 3.2e-05 0.004 18.1 0.6 1 23 289 311 289 311 0.99
3 22 2.3e-06 0.00028 21.8 1.1 1 23 317 340 317 340 0.95
4 22 0.014 1.7 9.8 0.4 1 23 346 368 346 368 0.98
5 22 0.002 0.25 12.5 2.6 1 23 374 396 374 396 0.94
6 22 0.00038 0.047 14.8 3.0 1 23 402 424 402 424 0.97
7 22 7e-05 0.0087 17.1 1.9 1 21 430 450 430 451 0.94
8 22 0.0015 0.18 12.9 0.7 1 20 499 518 499 520 0.95
9 22 0.0011 0.14 13.3 2.4 1 23 606 628 606 628 0.98
10 22 1.5e-05 0.0018 19.2 1.6 1 23 634 657 634 657 0.97
11 22 1.3e-06 0.00016 22.6 0.4 1 23 663 685 663 685 0.98
12 22 1.5e-07 1.9e-05 25.5 0.6 1 23 691 713 691 713 0.99
13 22 5e-05 0.0063 17.5 1.5 1 23 719 741 719 741 0.98
14 22 0.00014 0.017 16.2 2.4 1 23 747 769 747 769 0.97
15 22 1.4e-05 0.0018 19.3 1.1 2 23 776 798 775 798 0.96
16 22 0.012 1.6 10.0 2.6 1 23 870 892 870 892 0.98
17 22 4e-06 0.0005 21.0 1.0 1 23 898 921 898 921 0.96
18 22 0.00052 0.065 14.3 0.0 1 23 927 949 927 949 0.97
19 22 2.3e-06 0.00029 21.7 1.9 1 23 955 977 955 977 0.96
20 22 3.8e-05 0.0047 17.9 2.0 3 23 985 1005 985 1005 0.99
21 22 2.3e-05 0.0029 18.6 2.9 1 23 1011 1033 1011 1033 0.97
22 22 0.00017 0.021 15.9 1.7 1 23 1039 1062 1039 1062 0.97

Sequence Information

Coding Sequence
ATGGAAATGCAGGATTCAATAATTCTTCCTTCGTGCCATGATGAAGATGAAGTAATCGAGAAGGCTAAGACTACGGACATCGAAGAAGGAGAATATTTTCTAGTGTCCGATATTCTTGAGAATACGGAGGAAGAAGAGATGCAAGTTATTAATAAGGAAGAAGAAAATCCATTGATACCTGAAATGTGCAGGTTATGCGCGACTGTCAACAGCCATActattccaatttttaaaggagaaGGACTCGAACATGATTTATGTAGCAAGATAAATAAGCATCTACCTATAAAAGTGACTGAAAAGGACACTTTACCTCTTAAACTATGTTATCACTGTGCTGCTACTTTGTTAGCCTGGAACGATGTTTCTGAAGGTTGTTTAGAAGCTCAAAATCAACTTTTACGACTCCAGGCAGAACAAATgTCATCAGCAGATGACGAAGCGAGACCAGACCAGTTTGAagcaactgaaaatttcaaaggagaATATGTGgaGGAGAACCAACAACAAGACATGATTGATCTCAAAAATGTTGGAGACTCCGATTCTGAAAgGTCCAGTAGAGTCCAGGCATCATTTAAAGTATTCCTTGAtacacaaaatatatttcggaGGCCTTTGAAATCGACAATCACGGATAAAATATCGAATCTGCAAATCCCAATTGATGAAGAGCAAccaaaaaatgtgaaagatGAAGTTAAACCGGAACAAGGAGATGAATATCAGGAATTTCAACTCGATTCAGAAGTCGTCAACAGTGACAGTGAGGAATTTCACTGGCAATGTAAAATTTGCAATGAGGAATTCAATTCTGCAATTGAATTAAATGCTCACGCAAAACGTCACGACTCCAAAGAGTCTTATAGATGTCGAGAATGCGGAAGAGGCTTCAAAATCAAAGATTCGTACATCCGCCATGCTCGAATTCACAAAGACGAACGTCCTTTCACTTGCCATGTCTGTGGAAAACAATTCCGAGATTCTGGAGGACTTTCTCGTCACTTGAAGGACGTTCATGCCAAAGTCAAAAATTTCCCCTGCGATCTTTGTGAAAACAGTTTCGCTTCGAAAGCAACTAGAGATGATCATCGTAGAACTCACACTGGTGAACGACCCTACATTTGTGATTGTTGTGGAAAAACATTCAAGTCTAAAGCTTCTCTTTATATTCATAGCAAACTTCATACAGATGAGTTTCCTCATCCGTGTTCCTATTGCACAAAGAAATTTCGACGAAGACAGGAAATGCTGGCTCATGTGACAACTCACACTGGCGAGAAAAACTTTGCTTGTGATATTTGTCACAAACGTTTCAGGGTGAAGTCAGAACTCGTGAGACATCGGTGCGGTGTTCCGAGGACTTCATTCGCGACTTACTGTTCCATTAAGACAAAGAAAATCCAGAGAAGATTAGAATCAGCAAAATCTAAGAAGTCTCTAAAAACTGAAGAAGTATTTAATCAAGATTCAGCTCCTTCAAAAGTTTCCCAATATTCCTGTGAACACTGTGGATCGAATTTCGAGAGAAAATCCCCTTTGAAGTATCATCTAATCAACTGTTCTTCAAACATCGAACTCTtcaaaattgaggaaaaaCAACGTGAGACAGAAAGTGACTCTTCCAATCGCCATAGAAGGACGCGTCAAAAATCATACCCTTGTATGCACTGCGATTACGAtgctaagaaaaaaaagattttggaTCTTCATACGTTGGAAGCTCATCCAGAGTTGATAccttcgaaaaataaaagaagcatCGACAAACAAGCAGTTGATCAAGCGAAAATGGAAGTTAACGGCAAAATTTACTACCACTGTACAGAGTGTGGTAAAAATCTCTACTCTCCCTACACTTTTTCCTGGCACAAACGAATCCACACTGGGGAGAGACCCTTTACGTGTCATCTTTGTGGGAAGCAATTCCGAGTGAATCAAGGCCTAGCTCGCCACTTACGAGAAACTCACGCCGGAATTAAGAAATTCCCTTGTGATATTTGCGGCCGGATGTTCACCACGAAACGAAACGTTGAAGATCACAGAAGAATTCACACTGGCGAGAGACCTTACGTCTGCAATATTTGCGGAAAAGCCTTCAAACAAAAGGCGTCACTATTTGTTCATAATCGTACTCACTCGGATTTGTTTCCTTTTAAGTGTTCCTACTGTAATCAAGGATTTCGAACGAAAACCCCGTTGATGGTTCACATAACAAAACACACTGGTGAAAAACCATATGCTTGCGACATTTGCAATCGCCATTTTAGAATCAAGTTTGAGTTGAAAAGACACCGGCTTGTTCACTTTGATGAGAAACCCTGGCAGTGCACTGACTGCGATCTGTCTTTTCGACAGAAGAGGTACCTTGTTAATCACAGGAAAGTTAATCACGAGACGATTGCAagagaGTCCGAGTTGAATCAGAGAAAGAATAGGTTTATCTTCATCTCAATGCCGGGGATAGATGACGACGAGGATGAGAAAGAAGATCTCCTGCCACCCAAAATTAAACGGAAACGCGGACGTAAGCGTAAAGAGGATCTCGCTTTGGATCAACGACTTGAAATCAATGAAGCAAAGGTGGTGATCGAGGGGGTAACGTATTACAAATGTCGCGACTGTTCCAGGAATATTAGGAATCTTTACAACTATTTTCTTCATCGGAGAGGTCATCTCGGCGAGCGACCTTTTACTTGTCACAAATGTGGAAAAAGCTTCCCTTCACTTTCTGGGGTTAATCGACACGTTCGAGATGTTCACATGGGGTTGAAGAAGTACGAATGTGATATTTGCGGGAGACCTTTTGCCTCCCGAGTTGCTAAAAACGAACATAGACTAATACACACTGGGGAAAGACCCTATGTTTGTGAAATTTGCGGAAAAACCTTTACCCAGAAAGCATCTCTGCATGTTCACAAGCAATTCCATACGGAGGATTTGTCTCATTGGTGCACAATGTGCAGTCgaggatttaaaagaaagcaGGAACTCAACAAGCACATCTTGACACACACGGGGCAAAAACCCTTTGCTTGTGACATTTGTGGAAAGCGTTTTCGCAGCCAGGGTTGCATCAGTCGACACAAAAGGACTCACAGTCAACTGAAGAGTCACAAGTGCGATTTGTGTGGCGCAGCTTTTGGCCAGAAACGATATCTTAAAACCCACTGGCAGAccaaacacaaaaattcgtga
Protein Sequence
MEMQDSIILPSCHDEDEVIEKAKTTDIEEGEYFLVSDILENTEEEEMQVINKEEENPLIPEMCRLCATVNSHTIPIFKGEGLEHDLCSKINKHLPIKVTEKDTLPLKLCYHCAATLLAWNDVSEGCLEAQNQLLRLQAEQMSSADDEARPDQFEATENFKGEYVEENQQQDMIDLKNVGDSDSERSSRVQASFKVFLDTQNIFRRPLKSTITDKISNLQIPIDEEQPKNVKDEVKPEQGDEYQEFQLDSEVVNSDSEEFHWQCKICNEEFNSAIELNAHAKRHDSKESYRCRECGRGFKIKDSYIRHARIHKDERPFTCHVCGKQFRDSGGLSRHLKDVHAKVKNFPCDLCENSFASKATRDDHRRTHTGERPYICDCCGKTFKSKASLYIHSKLHTDEFPHPCSYCTKKFRRRQEMLAHVTTHTGEKNFACDICHKRFRVKSELVRHRCGVPRTSFATYCSIKTKKIQRRLESAKSKKSLKTEEVFNQDSAPSKVSQYSCEHCGSNFERKSPLKYHLINCSSNIELFKIEEKQRETESDSSNRHRRTRQKSYPCMHCDYDAKKKKILDLHTLEAHPELIPSKNKRSIDKQAVDQAKMEVNGKIYYHCTECGKNLYSPYTFSWHKRIHTGERPFTCHLCGKQFRVNQGLARHLRETHAGIKKFPCDICGRMFTTKRNVEDHRRIHTGERPYVCNICGKAFKQKASLFVHNRTHSDLFPFKCSYCNQGFRTKTPLMVHITKHTGEKPYACDICNRHFRIKFELKRHRLVHFDEKPWQCTDCDLSFRQKRYLVNHRKVNHETIARESELNQRKNRFIFISMPGIDDDEDEKEDLLPPKIKRKRGRKRKEDLALDQRLEINEAKVVIEGVTYYKCRDCSRNIRNLYNYFLHRRGHLGERPFTCHKCGKSFPSLSGVNRHVRDVHMGLKKYECDICGRPFASRVAKNEHRLIHTGERPYVCEICGKTFTQKASLHVHKQFHTEDLSHWCTMCSRGFKRKQELNKHILTHTGQKPFACDICGKRFRSQGCISRHKRTHSQLKSHKCDLCGAAFGQKRYLKTHWQTKHKNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01392948;
90% Identity
-
80% Identity
-