Basic Information

Insect: Sycophaga agraensis
Gene Symbol: Hr39
Assembly: GCA_018906755.1
Location: JACCIE010000040.1:450415-455012[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 2.4e+04 -6.9 6.3 114 147 201 240 97 306 0.46

2 3 2 2.4e+04 -8.9 10.1 78 140 262 338 188 368 0.51

3 3 2.5e-76 2.9e-72 244.7 0.2 1 408 454 857 454 857 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	2.4e+04	-6.9	6.3	114	147	201	240	97	306	0.46
2	3	2	2.4e+04	-8.9	10.1	78	140	262	338	188	368	0.51
3	3	2.5e-76	2.9e-72	244.7	0.2	1	408	454	857	454	857	0.79

Sequence Information

Coding Sequence: ATGCCGAACGAACGCCGCGACCCTGGTAGAATATTGACCCGCTTTTATGGTCGACGTCCTAATGGAGACTTCAATTTAGAAATTTCATCTAACGCCGAACTGGTGGATCGTGGACCAGGTTTTTATGGCTGGCGTGTTAACCGAGTGGAGAACGCGACACTCATCGACGGGGACAGCGACGGCGAGGTGAGCCGCATCGACTTCCGCGGCGTGAACCTCCGCACGAAGAAGAAGCGCGAGGGCCCGCACGGCAGCCTCGGCTCGGCCCTCGAGAGCCCCGGGAGCGAGGTCCACCACCAGCAGCCGGAGCGCCCCATGTCCTGGGAGGGCGAGCTCTCCGACCAGGAGATGAGCTCCAACACGATCACGAACCAGGACCACGAGGAGACGTCGATGGAGGGCGTCCAGGTGTGCAGCTCGAGCCCCGGGCCCCAGGAGCACAAGTTCCCCCTCCTCGGCGGCTGCAACAGCTCGACGCCGAACCACAGTCCCGTCCTCATACCCCGACACCACCTCACCAAGCACAGCCACACCAGATCTCAAGGTCCTGCTGCGCGGTGGGACCACCGGCCCGCCACAGCGTATGTGAGGGCGTACACTAATGCCTGCGGGGTTTTTGGCAAGCAGGTACCGTCGCCGGACTCGGCGATCCACTCGGCCTACAGCGTGTTCAGCTCGCCGACGCAGTCGCCGCACGCGGGCCGGCACTCGGCCCTGGGGCCGGGCTCGCCCGTGCCCTCCTCCTCCCTGTCGCTCTCCCGGCACAGCTTCAACAACTCGACCTCGAGCCTCTCCCTCTCGCTGTCGCACTCGCTCTCGCGCAACAACTCGGACGCCTCGAGCAGTTGCTACAGCTACGGCTCCCTCAGCCCGCCGACGCACTCGCCGGTCCAGCAGCGCCACGCCCACCACCACGGGGTCGGGGGCCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCACGTGCCCGCGGGCCTGCAGTACGCGGCCGCGGCGGCGGCGGCTGCTGCGGCTGCGGCGGCCGCCGCCCAGGGCCACGGCCTCGGGGCCGACCAGCTGGCGGAGGGCCTCCACCCGGACGAGCAGGAGGACTGCCGTGCGCCCTCGGCCCCCGCGGGCATCTCCACGCGCCAGCAGCTCATCAACAGCCCCTGCCCCATCTGCGGGGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAACCGGAAGAACTACGTGTGCCTGCGGGGCGCCGGCTGCCCCGTGACCGTCGCCACCCGGAAGAAGTGCCCCGCGTGCCGCTTCGACAAGTGCCTCAACATGGGCATGAAGCTCGAGGCCATCCGCGAGGACAGGACGCGCGGCGGCCGCAGCACCTACCAGTGTACCTATACCCTGCCGGCGAGCCTGATGGCCGGCCCGGGCGCCGGCCCCGGGCCCATGCCGCCCGACAAGCTGGCCCAGGCGGGCAGCCCCGCCCCGCCCGGGGCCGACCACCACCACTCGGCCAAGCACCACTCGAGCCACTCGCACAAGCTCCAGCTGGTGCCCCAGCTACTCCAGGACATCATGGACGTGGAGCACCTCTGGCACTACAACGACAGCGACCGGGTCGGCGCCAGTCAGGCCATGGGCTCCCTCAACCTCACCCAGTCGTTGCCTCACGCGGGTCTGGGCAACAGCGCGTGCGGCGGCAGCAGCAGCAGCGGCAGCGGCGACTCCCTCAGCGGCCCGGGGACGGCCAACGGCCTGAGCAGCGGCGGCAGCGCCGGCGCCGGCAACGGCAGCAGCGGCGGCTTGAGCAGCGCGACGAGCAACGGCAGCCTGAGCAGCAGGAGCGAGTCCGCGCGGTACAGCCCGCCCAGCTCCTCGACGCCGGCGCCCAGCCTCGAGCAGCAGCAGCAGTCGCCGGCCCCGAGCGCCTCCCCGAGCCCGGGCAACGGCAACCCCACCCAGCACCCCGACTTCCTCTCGAACCTGTGCAATATCGCCGACCACCGGCTCTACAAGATCGTCAAGTGGTGCAAGAGCCTACCGCTCTTCAAGAACATCTCCATCGACGACCAAATCTGCCTGCTGATCAACTCCTGGTGCGAGCTGCTGCTCTTCTCCTGCTGCTTCCGCAGCATGAGCACCCCGGGGGAGATCCGCGTCTCCCTCGGCAAGTCCATCACCCTCGAGCAGGCGCGCCAGCTCGGCCTGGCCACCTGCATCGAGCGCATGCTCGCCTTCACCAACAACCTCAGGCGGCTCAGGGTCGACCAGTACGAGTACGTCGCCATGAAGGTCATCGTCCTCCTCACGTCGGACACGAGCGAGCTCAAGGAGCCCGAGAAGGTCCGGGCGTCTCAGGAGAAGGCCCTCCAGGCGCTGCAGCAGTACACGATCGCGAGGTACCCGGAAATGCCGGCCAAGTTCGGCGAGCTCCTCCTCAGGATCCCGGACCTCCAGCGCACTTGCCAGGCAGGCAAGGAGCTACTCAGCGCCAAGCGCGCCGAGGGCGAGGGATGCTCCTTCAACCTGCTCATGGAGCTCCTGCGAGGGGACCACTGA
Protein Sequence: MPNERRDPGRILTRFYGRRPNGDFNLEISSNAELVDRGPGFYGWRVNRVENATLIDGDSDGEVSRIDFRGVNLRTKKKREGPHGSLGSALESPGSEVHHQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCSSSPGPQEHKFPLLGGCNSSTPNHSPVLIPRHHLTKHSHTRSQGPAARWDHRPATAYVRAYTNACGVFGKQVPSPDSAIHSAYSVFSSPTQSPHAGRHSALGPGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQRHAHHHGVGGQQQQQQQQQQQHVPAGLQYAAAAAAAAAAAAAAAQGHGLGADQLAEGLHPDEQEDCRAPSAPAGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPASLMAGPGAGPGPMPPDKLAQAGSPAPPGADHHHSAKHHSSHSHKLQLVPQLLQDIMDVEHLWHYNDSDRVGASQAMGSLNLTQSLPHAGLGNSACGGSSSSGSGDSLSGPGTANGLSSGGSAGAGNGSSGGLSSATSNGSLSSRSESARYSPPSSSTPAPSLEQQQQSPAPSASPSPGNGNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGCSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01380052; iTF_01380029;
90% Identity: iTF_01380052; iTF_01380029;
80% Identity: iTF_01380052; iTF_01380029;