Basic Information

Insect: Subacronicta megacephala
Gene Symbol: Hr39
Assembly: GCA_958496365.1
Location: OY292516.1:13451596-13469496[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.11 8.1e+02 -0.2 4.6 97 194 219 344 129 372 0.54

2 3 6.1e-08 0.00044 20.5 0.1 1 20 445 464 445 472 0.91

3 3 8.1e-65 5.9e-61 207.8 0.0 150 408 496 763 471 763 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.11	8.1e+02	-0.2	4.6	97	194	219	344	129	372	0.54
2	3	6.1e-08	0.00044	20.5	0.1	1	20	445	464	445	472	0.91
3	3	8.1e-65	5.9e-61	207.8	0.0	150	408	496	763	471	763	0.85

Sequence Information

Coding Sequence: ATGGTGATGAGTACAACGATGAGCAGTGAGGGAGACGCGGTGAAGGTGGAGGGGGGACACGTGTCTGTCACCACTATCAGCATGTCGGGTCCGGAGACAAGCAACGGTCAGTTCTCGTACAGTTCGAGCGGCGTACGAATCAGTGTGTCTTCAGAGCCACATGATGAAGACTCCACTGACGCCGAAATCTCCAAGATCGACTTCACACAACATCAGTATGAGGTGAAGATGCGTAACAACAAGAAACGTTCGTCAAATGGGGCCCACTGCGATCTAGCTGCCAACGAGCGGGAACGACCCATGTCCTGGGAGGGAGAACTCTCCGACTCAGAAATGGTCATAGATACCAGTGTTAATAATGACGACAACAGCAGTTCTCTGGACCTCCAATCCTCCAGAGATTCGATCGATACCCTTCGGAACGTGAGCATCAAGACGGAACCTCTCAAAACCGAGGGTTTTCAAAACCTGGATGAGCAGCGCGTTTTAGACCTCAAATACAGCGCGCCATTACAGCCGCATCAGAGGAGCCATAGCATGAACAGGATATCAGTACTAACGGACGGCACATCACTATCTCTAGCGAGGCGGCCTTCCTCTCCGACCAGTAGTGCCAAGTCTCTCGCGCTCAGTGACCAGGGCTCAGCCCCTATGTCCCATGCAGGCCTAGACCAAGTCCAGAACTTGACCATCAAAAAAGAGACGCAACTTTCTGAGTTGAAGTGCGAGCAGTCAGTGGGTATGGAGAAGTTGATTGGTGCGTTACACGGATCTCCACTGCTGGGCCGGCTGCCGCGCGTCCAATCCAGCGCCAGCACCGACTCCGCCGTGCACTCCATGTACACACACAGTGTGTACAGTAGTCCGTCAGCAAGTCCCCGCGCCTCGAGGCACTACACGCCCTCGTTGTCTCGCAACAACAGCGACGCGTCGCACTCCTCATGCTACTCTTACAGCTCCGAATTCTCACCCACTCACTCTCCAGTACAGGGTCGTCACCCACAAGTGATGTACAGGGAGGCTGCGGCAATATACGACGGTACACATGATGACGAGCCTGACGCGCCCGAAGACAGGCTTCATCACCACCAGGGTATAAGCAGACAACAGTTGATTAACAGCCCTTGTCCGATCTGCGGCGACAAGATCAGCGGGTTCCACTACGGGATATTCTCGTGCGAGTCGTGCAAGGGTTTCTTCAAGCGCACGGTTCAGAACCGTAAGAACTACATGTGCTTGAGGGGCGGCAACTGTCCCGTCACTGTCACCACCAGGAAGAAGTGTCCTGCGTGCCGGTTTGACAAGTGTTTAGGATGCGGAATGAAGCTAGaagCCATAAGAGAAGACAGGACCCGGGGCGGTCGCTCTACGTACCAGTGCTCATACACGTTGTCGGGCGCTGCGTCTACGGGCTCCTTATTGTCTGCGCACGCGCCGACCACGCTTCGGCACGCCTCCAGCCTTACCTGTGTGAACGGCCCAGGTTCGTACAGCAGCCGAGGGGAATCCAGTAACAGTCAAGTTACGCCAGATATACCGCCATTATtgcaggAAATAATGGACGTGGAACATCTCTGGCAGTACAACGAGTCCGAGTTAAGCCGGCTAGGCAAGTCTACCGGCAGCCCCTCCGCCAACCCGCTGCTGGCGGCGAGCGGCATCACAGCCCACAACTCCAGCCCCGACTTCCTCGCCGACCTGTGCAACATCGCCGACCATCGACTCTACAAGATCGTCAAATGGTGCAAGAGTCTACCGCTCTTTAAGAATATTtcgATCGACGACCAAATCTGTCTGCTGATCAACAGCTGGTGTGAGTTGTTGGTGCTATCGTGTTGCTACCGCGGCGTGAGCACTCCCGGAGAGGTGCGCGTGGGGGGAGGGCGCGGCATCACGCTGCACCAGAGTGCTAAGTTAGGATTGACGCCATGTATAGAGCGCATGCTGAGCTTCACAGACCACTTGAGAAGATTGCGAGTGGACCGGTACGAATATGTCGCGCTCAAAGTCATCGTGCTACTTACTTCAGATGCTCCTGATTTGCGTGAAGTGGAGAAAGTGCGAGCATCGCAAGAGAAGGCGTTAGCGGCACTGCAGGCCTACATTGCAACGCACTCCCCTGGCACTCCCGCTAAATTCGGAGAGCTGCTGTTACGCATACCTGAACTGCAAAGGACTTGCCAGTTCTTTATGCAAGTTGGTAAAGAAATGCTGAATCCAGCTAACAAGAGCAAAGATGGCGACGGGCCAAGCTTCAACCTGCTCATGGAACTGCTGCGCGGCGACCACTGA
Protein Sequence: MVMSTTMSSEGDAVKVEGGHVSVTTISMSGPETSNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVKMRNNKKRSSNGAHCDLAANERERPMSWEGELSDSEMVIDTSVNNDDNSSSLDLQSSRDSIDTLRNVSIKTEPLKTEGFQNLDEQRVLDLKYSAPLQPHQRSHSMNRISVLTDGTSLSLARRPSSPTSSAKSLALSDQGSAPMSHAGLDQVQNLTIKKETQLSELKCEQSVGMEKLIGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPQVMYREAAAIYDGTHDDEPDAPEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVTTRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPTTLRHASSLTCVNGPGSYSSRGESSNSQVTPDIPPLLQEIMDVEHLWQYNESELSRLGKSTGSPSANPLLAASGITAHNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLREVEKVRASQEKALAALQAYIATHSPGTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042698;
90% Identity: iTF_00806824;
80% Identity: iTF_01377601;