Basic Information

Gene Symbol
-
Assembly
GCA_963971135.1
Location
OZ020180.1:13586136-13595105[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 2.1 3.1e+02 3.4 0.6 7 23 21 37 15 37 0.89
2 25 0.00014 0.022 16.5 1.0 1 23 77 99 77 99 0.97
3 25 0.00012 0.018 16.8 1.0 1 23 105 127 105 127 0.98
4 25 2.3e-05 0.0035 19.0 2.9 1 23 133 155 133 155 0.98
5 25 0.00018 0.027 16.2 4.0 1 23 161 183 161 183 0.97
6 25 0.00027 0.04 15.7 5.7 1 23 189 211 189 211 0.97
7 25 1.2e-05 0.0018 19.9 2.4 1 23 217 239 217 239 0.98
8 25 2.8e-05 0.0043 18.8 2.8 1 23 245 267 245 267 0.98
9 25 0.0055 0.83 11.6 2.1 1 20 307 326 307 328 0.95
10 25 3.1e-05 0.0047 18.6 7.7 1 23 365 387 365 387 0.98
11 25 3.9e-06 0.00058 21.5 0.6 1 23 393 415 393 415 0.98
12 25 0.00011 0.017 16.9 2.1 1 23 421 443 421 443 0.98
13 25 0.0011 0.17 13.7 4.1 1 23 450 472 450 472 0.98
14 25 0.006 0.9 11.4 2.4 1 20 509 528 509 530 0.96
15 25 4.9 7.3e+02 2.3 1.5 1 19 537 555 537 555 0.94
16 25 4.2e-05 0.0064 18.2 3.3 1 23 564 586 564 586 0.98
17 25 9.1e-07 0.00014 23.5 0.6 1 23 592 614 592 614 0.98
18 25 3.9e-05 0.0059 18.3 4.7 1 23 620 642 620 642 0.98
19 25 2.3e-05 0.0034 19.0 3.8 1 23 650 672 650 672 0.98
20 25 0.0012 0.18 13.6 2.5 1 23 678 700 678 700 0.98
21 25 8e-06 0.0012 20.5 1.6 1 23 706 728 706 728 0.96
22 25 7.7e-06 0.0012 20.5 1.0 1 23 734 756 734 756 0.97
23 25 0.00013 0.02 16.6 2.9 1 23 763 785 763 785 0.98
24 25 5.8e-05 0.0087 17.8 0.5 1 23 791 813 791 813 0.98
25 25 0.00043 0.065 15.0 2.0 1 23 819 841 819 841 0.96

Sequence Information

Coding Sequence
ATGGAAAAGGAAGTCCTCGAGGAACACACTGATGAAAAACCGTTCGAATGTGAAATCTCCAATAAAAAGTTCAAAGAAAATCAATCACGTAAAAGACATTTGAAGATTCACACGGGCGAAAAGTCTTTCGAATGTGAATtctGGAATGATTCTTCAAGTGGAACAAAAGTCTTTACCGAAGAATTTCTTCAACAAAATGGACATGAAAATCCTGAGAAACAGAAACTATTTGAATGTTtacaatgtaataaaaattttgcctACAAAAATGGTCTTAAACAGCATTTAATGCTTCACACAGGTGAAAAACCATTTGAATGTACATATTGTGATAGCAAATTTCCCACCAAGCCAAGACTTAACGTTCACCTAAAAACACACACTGGTGAAAAACCTTTTGAATGTGAATTCTGCCAAAAAAAGTTCACACAAAAGCGAAATTATCAAAGTCATTTGCTGATTCATACTGGCGAAAAACCTTTCGAATGTGAATTCTGTAATAAAAAGTACATTCAAAAGCGACATCTTCAAAGTCATTTGCTAAATCACAAAGGCGAAAAACCTTTCTTTTGTGAAcactgtaataaaaattttacagaaaaGCGATATCTTGACAAGCACCTGAAGACACACACTGGTGAAAAACATTATGAATGTGAAATCTGCAATAAAAAGTTTACAGTAAATCACGTACTTAAAAACCATATGCTTAAACACACGGGCGAAACACCTTTCGAATGTGAATTATGTAGCAAAAAATTTACGGAGAAACGATATCTTAACACCCACCTAAAGACACACACTGGTGAAAGAGATTTTGAATGCgaaatctGGAACGATTCTTCAAGTGGAACAAAAGTCTTTACCGAAGAATTTACTCAACAAAACGAATCGGAAAATCCTAAGAATGAAGAACTGTTTCAATGCCGGCGTTGTAATAAAACTTGTACCCAATTAAGGAGTCTTGAAGAGCATTTGACACTTCCCACAGGTCAACAACCATTTGAATGTACATTTTGTAATAATGAACTTAACAGTCACCCTACAAGAGACACTAGTGGAAAAGCGTTTATTGGCACAAATGAGAAGCCGTATGAATGTGAactatgtaataaaaaatttacaaaaaagcaTCATCTTAAATCACACCTAAAATCACACACTGGTGAAAAACCATTTGAATGTGAAATCTGCAATAAAAAGTTTACCGAGAATCAAGGACTTAAAAGACATTTGCTCGTTCACACGGGCGAAAAGCCTTTCGAATGTGAagtatgtaataaaaaatttgcatataaGTTTCGTTTGAAGAAGCATGTGATTAAGCATAATAAAGTTAAAGTTAGTTTCGAATGTGAATATTGCAAAGAAAAGTTTACAGAAAATCACAGATTTAAAAGACATTTGCTCATTCATACGGGAGAAAAgccttttaaatGGAACGATTCTTCAAGTGGAACAAAAGTCTTTACCGAAGAATTTACTCAACAAAACGAATCGGAAAATCCTAAGAATGAAGAATTGTTTCAATGTTGGCAATGCAATAAAACTTGTACCCAAATAAGAAGTCTTAAAGAGCATTTGACATTTCCCACAAGTGAACAACCATTTGAATGTACATTTTGTAATAGTAAAGTCACGACCAAGAGAAGACTTAGCAGTCACCCTACAACAGACACAGATAAGCCGTATGAATGTGAactatgtaataaaaaatttataaaaaagcaacATCTGGTATCGCACCTAAAATCACACACGGGTGAAAAACCATTTGAATGTGaaatctgcaataaaaatttcACCAATAATCAAGGACTTAAGAGACATTTGCTCATTCATACGGGCGAAAAGCCTTTCGAATGTgaattatgtaataaaaaatttgcacATAAGTATCATTTGAAGGAACATGTAATTAAACATAAAGTTAAAGTTAGAAATAATTTCGAATGTGAACACtgcaaaaaaaagtttacaGAAAATCGAGCACTTAAAAGACATTTGCAGCTTCACAAGGGCAAAAAGCCTTTCGAATGTGAAATATGCAACAAAACATTTCACGAAAAGTACAGATATGAAACGCATTTGTTAATTCACACCGGTGAAAAACCGTTTGAATGTGAATTTTGTAAGAAATCATTTTCTGATAGGGGAACGCTTAAACGGCATTCATTAATTCACCAGAGTGAAAAAGCTTTTGTTTGTGAATATTGCAATAAACAGTTTACACGAAAGTATGTATTAAATCAACATATATTGGCTCATACAAATAATGATAAACCATATGAATGTAAACCTtgtaataaaaagttttctaaaaAGCAATATCTTAACACTCACCTAATGACACACACCGGTGAAAAACCTTTCGAATGTGAAATCTGTAATAATAAGTTTACAGAAAATCGAGCACTTAAAAGGCATTTGCTGATCCACAATGATGAAAAGCCTTTTAAATGTGAACTAtgcaataaaacattttccagAAAGTACATCTATGAAACGCATCTGTTACTTCACAAAAGTAAAACAACCGTTTGA
Protein Sequence
MEKEVLEEHTDEKPFECEISNKKFKENQSRKRHLKIHTGEKSFECEFWNDSSSGTKVFTEEFLQQNGHENPEKQKLFECLQCNKNFAYKNGLKQHLMLHTGEKPFECTYCDSKFPTKPRLNVHLKTHTGEKPFECEFCQKKFTQKRNYQSHLLIHTGEKPFECEFCNKKYIQKRHLQSHLLNHKGEKPFFCEHCNKNFTEKRYLDKHLKTHTGEKHYECEICNKKFTVNHVLKNHMLKHTGETPFECELCSKKFTEKRYLNTHLKTHTGERDFECEIWNDSSSGTKVFTEEFTQQNESENPKNEELFQCRRCNKTCTQLRSLEEHLTLPTGQQPFECTFCNNELNSHPTRDTSGKAFIGTNEKPYECELCNKKFTKKHHLKSHLKSHTGEKPFECEICNKKFTENQGLKRHLLVHTGEKPFECEVCNKKFAYKFRLKKHVIKHNKVKVSFECEYCKEKFTENHRFKRHLLIHTGEKPFKWNDSSSGTKVFTEEFTQQNESENPKNEELFQCWQCNKTCTQIRSLKEHLTFPTSEQPFECTFCNSKVTTKRRLSSHPTTDTDKPYECELCNKKFIKKQHLVSHLKSHTGEKPFECEICNKNFTNNQGLKRHLLIHTGEKPFECELCNKKFAHKYHLKEHVIKHKVKVRNNFECEHCKKKFTENRALKRHLQLHKGKKPFECEICNKTFHEKYRYETHLLIHTGEKPFECEFCKKSFSDRGTLKRHSLIHQSEKAFVCEYCNKQFTRKYVLNQHILAHTNNDKPYECKPCNKKFSKKQYLNTHLMTHTGEKPFECEICNNKFTENRALKRHLLIHNDEKPFKCELCNKTFSRKYIYETHLLLHKSKTTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01371903;
90% Identity
iTF_01371903;
80% Identity
iTF_01371903;