Sbip015367.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Stenoptilia bipunctidactyla
Gene Symbol
egg
Assembly
GCA_944452705.1
Location
CALYCB010000727.1:493882-566757[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.3 1.4e+04 -3.0 0.0 28 38 1431 1443 1406 1444 0.68
2 2 2.5e-11 2.8e-07 31.3 0.0 4 75 1475 1539 1472 1541 0.87

Sequence Information

Coding Sequence
ATGCCTAAGGCTGTAAAAAGTGATGCACGAATAATTATACTAAAAGTATTAGCTTTTATGAAGGATGAAAAACGTGCACAGCAGCCAATAATACCATTCGAAAAGCTGTATGAACGCGTTGCTGCAGCCACAGGTGTTTCTGAGCGATTCTTACACAAGTTAGTTAATGAACAAAAATTGGCTCAAGAATGTGGCACTAAAATTGAAACACCAGGCAAAAAGAGAAACAGGACTTCAGAAGAGATGGAAGATGAGGCTCCCAAAATAATATCAATGGATGAAAGCTCTATAGCCAACTCCGACGACAAACGTGCAAACTCAACATCAAACGATTCCAAGATTCTATCTGGCCGAAGTTCTACTTCCGATTTAGGCTTAAGTGATCCGTGTGACTCTAAAGTGACTACTACTTCAAGTTCGAGCGATGTGCTTGTCACAGAAGATGTGGATTTGGACAAAACTAGGTCTAATGATATTGAAGATAATGATGTTATCATAGGTAAAATTGACTCATTACTGGAAAATACTGTGGATGACGATGAAGCTTGTAGTGATTTGATAGACGAAGATCTTAAGTTACATTGGGATGAAGAAGAAGAAACCGATAACCCAGATAAAATTCAAGCAGTTATTGATGCACATACGCCAACTTCAGAAGTTTTTGAATCGAAATCTCCTCAAAATCCCAAAACAATTGATCTAAACAATGCAGCTCAAGAAGCTACTGTAGAAAGTTTAGGAAACAATGAAAATGCTTCTAACGAACTTGATGAAAGTAATAATAAGCATGCTAAAGATACAATTATTTGTCAAAGTTCAGAGGTGGATACTTCAATGAATCTACCTTTACCACATGGCCTTATGAAGCCAGACCAAATGATTGAAATTCCAACTCAAGAGCTTATTGATATTGATGATTCTTGCCTTTTAGATGACACTAGCAAAATGGTAGCTCATGAAAGTATTGAAGATGATAATTTAGAAGATTTGGAAGCTGAAAATAAACACAATGAAAATATGCAGTATGAAAATATAGAAAATGAAAATATAGAGGATGAAAAATCAGTAGAAGAAAAACTTATTGAAGTAGCAAAGTCTTGTGATACCACTCTTCTTGGAGACACAATAACAATTGATAGTTCTGATCATGAAGAAAATGATGTGATAAGTATTGTTACCAAGAAACAGGAAGAAAAATGTGCTGAAATAATTGATGACACAATAGAAAACAGAGAACCTGAGAAAAAAATTAGTAAAAATGATGAAACACTTTCCAAAAGTGATGATCTCACAGAAGTTTCTTTAGAGCCCAAAGTTTCTGTCCCCGGCACAGTTAACTCTGACATAAATGTTCAGAGCATGATAGGAGAGAATAAAGAAAACTGTAAAGACCGTGAAGATATGTCTTTGGAAATGAAGGATGAAGTCACAGATCTGCTTGATTCAAATAAAGATGTAAATAAAATTATAGGTGACACAAATGAACCAAATTCACCTCGTAAAAGTGATGAATCTGATGCTAGTAACTCAAAAGCGCCATCTGTTTTCTCATCCTTGAATCCTAAACCAACAATATCAACAGCAGAAGAATTAGAAGCAGCAGACACGGAGGTCACAGAAGTAGATGATAGTTTAGGTCTTTTGGCGGAATCTTCTAGAATGATGGAAGATGACGATGATGAAGATGAGGCTGAAGCTGATGCTGATGCTGAAGTGGATGATGATGATGATGGTGATCCTGAATATGATCCAGATGAAGACAGTAATCAAGTATCCTGTGATCAGTCTGAAGATTCCAATGCACCGCAGTCTGAAATGGAGCAGCCTAAAGATGGTACTGAGGTTACTGCAGAAGATGAGAATGAAACTCCCTCTCCGACGGATGAGAACAAAGAGTTTGACTTTAGAAGCATTGCTAATGATACGGCTGAAGTTGATGATAAAGATGAGATGGATATTGATATGATTGAATGTGAAGAGATGGAAGTTCCATCTCCAACCAATGGAGATGATACCAACAAAGTTACTGATGAGGGGCAGAAACAACCGAAGGAGCAAGCACCAGAAGTTAAGACTGGGGAACTAGTAGAGGAACCGAAGACTTCTGCTGGGTCGACATCACAGGATGAGCTCAAGACCTCCGAAACTACAGATGAATCCATCCCCGTTAAGATATCAGTGTTGGAGACCCTACTTCTTGATCCACCAAAACCGTTCACTGTCAGTCCGTCTATGTCGAAGCCAGTTGGGAACGTGCCATCGGCTGTGTTCAACATTGTGGAACTGGAAGAAAGCTCATCTGAAGATGATGTGCAAGAAGTAATAAAAGAAATAGAGAGGACAGACGTAAACATACCAAAGGGCATAGAAGTGACTGCGTCTTCCGGTGGCAGTATGTCTGAGATTGTCACTAAAGAGGATGAGTTGGTGATAAGTGGGGTACCCAAACCAGCTTGCAAGAAATTAAGTAATATGACCCGTTTGAACACAAGTGAACTAACTATCAAGACGTGTGCCACTGAATCGACGCTAGTGATACCCGAGACCAAGGTTGGTAAGGAAGAATCTATCAAACCCAAAATGGGCCTGGAAGTGTTCAGCCTGGACTCCGATGACGATGAAAACACTATTCCAGAGCCGGTCCCGTCTCCGCCAAAACCCCGCACGTACAAATGCGTGAACCCGGGATGCACCAACGCGGCAGTGTTACGCGCTTCCCGGAGTATTCTCTCCTACTACGCCGTGAAGACCAAGAAGAAACGAGTGTGTAGATCCTGTGCCCGCGCTGTTACTGCGGAACAAGAGAAACTAGTTGATGGTCTTCTCAACTTCACTCCACTTCTGGAGTTAGACATGGAGCCTCCAGCGCAGCAGTTAGTGGAGATCTCAGACTCTGATGAAGAAGATGTAGAAGATGAAAATGAACATAATCAGCTGATTGGAGAGAGTGGTGCTAAATTCCTCGAGGCTCAACTCGCAGACATGATCAACATGACCTGGAAGAAACTGAATATGGATGTAAGGTTGGACGAGGTGCAGAAATCGCTGCTCAAGCAGATGGACAGCTTGCAAGAGGAAAGCAAGGAAGTCGACAGCATGCTGTCAGAATGCCAGATCGCTACTGACAAGCTTCGAAACGAGTTGTATCGCACCTTCGAGCACAAACGGCACGAGCTGCCTGCGATAGTCATCTTCGATACGAAGCCGGATAAAACGGACAGAGTATTCGGAAAACGTCGTATGTCGGCCTGCGAAAACCCGGCGGCCAAACGACCGGCCGTCCCAGTGGACATTGAAAATCAAAAAAACACAGAGGTGTCAGTAGTGAAACTGTGCGCGGAGACCGCCCCCACGTCCCTCCCAGCCGTGGGGGAGATCATACGTCCACCGTTGAAGATAGGCCAGCCAGTGTTCGCCATGAGAAACGCTTTCGGGGCGTGGACTAAAGCCAAGGTCATGGATATAACGCCGCCTAAGGAACAGCACAACCAACAGTTCTCGATGTGTCGTGTGAAGTTCGAGCAGAAACAAACGAAATCTCCCTTCAAGATGCTCTCCGCGCGGTGTTTAGCCTACATAGACCCGCCCGACGTCAGACTTACTATTGGTACTCGAGTGATAGCGCTGTTCAAAAACAACGAGGACCTACGAAGGGAGTCGTATTATTCGGGAGTTGTGGCGGAAATACCCAACCCCGTTAATAAATACAGGTACCTAGTATTCTTCGACGACGGCTACGCGCAATACGTGCAGCACCAAAGCACCCGCCTCGTGGTCGAGAGTTCGGTGTCCGTGTGGGAAGAAGTGCATCCGTTTTCCAGGGATTTCGTGAGGAAGTATTTACTGTCTTTCCCGGAGAGGCCGATGGTTAGATTGCACGCAGGGCAGAGTATCAAGACTGAGTGGAATGGTAAATGGTGGGTGTCCAAAGTGATTCAAGTGGACGCATCGCTAGTGCAAGTCCATTTCGAGGGCGACGAGCGAGTGGAATGGATCTACCGCGGGTCCACTCGCCTGGCGCCGCTGTATATGGAGTTGCAAGGCGCGCGCGGCGCCGCGCGGCCCGCGCGCCCCGTGCGCCGCGCCGTGCCCAGAGCCAAGCCCGCCGCCCTGAATAACCAGCCGTATGTGGAGTACACACGATCTGACGAACAAAACAGCAAGTCCGCTGAGACGCAGAAAGCTCAGCAGAAACAGGAAGATGATATTCGGCGCCAACGGGCGGTGGCTAGAAAATCGACGGCCGTACAGAACGCGCCGCCCGCGCCCACTAACGCGCAAGGACTGTCCGCTGATAGCGTTACCAGCAGAGTTGTGTACTACACACCCAAAAACGCAGTGAAACCGTACAAGATGAGCCCGCACCAGTGCGGCCCGCGCTGCAAGCGCAGCGACGTGCTCTCGCTGAAGGAGCTGCGGACCTACAACCCGCTCGCCAAACCCTTGCTCAGTGGCTGGGAGAGGCAAATAGTCCGCGTAAAAAGCCACCGCGCGTGCATGTACCGTGCGCCTTGCGGGCGCCGGCTGCGGAACCCACGCGAGCTGCACGCCTACCTCACCATGACCAACAGCGATATGGGCGTCGATCTCTTCGACTTCTCTCCTAACACGCACTGCTTGGCTGAGTTTGTGCTGAATAAATGCCTTGTCGGAAAGAAGGATCTATCCCACGGCAGAGAGAACGTCCCGGTCCCGTGTGTGAACTACTACGACTCGACGCTACCTGAGTTCTGTTCGTATAATACAGAACGCACGCCCACCGCTGGGGTGCCGCTTAATCTGGACCCCGAGTTCCTGTGTGGATGTGATTGTACGGATGATTGCCAGGATAAATCAAAATGTGCGTGTTGGAAGATGACTCTAGAAGGAGCTAGAACGATAGGTTTGGGCAAGAACGTCGGGTATGTGTATAGAAGACTGCCTGAGCCTCTGCCTTCGGGGATTTACGAGTGTAATTCTAGATGTAAATGCAAGAATACATGTTTGAATCGAGTCGTACAACATCCGTTGCAGTTGAAATTACAGGTTTTCAAGACACTTAACCGCGGTTGGGGAATAAGGGCATTGAACGATGTACCGAAGGGATCTTTCCTCTGTATTTACGCCGGCAACCTTCTTACAGATGCGACGGCTAATTTGGATGGCCTTAACGAGGGAGATGAATATTTGGCAGAGCTGGACTACATCGAAGTTGTGGAGCAGATGAAGGAAGGCTACGAAGATGACATACCTGAAGAAGACAAGGAATTGGATAGAGAATTGGAACGACATGCCACTGAGTTCCGTACACATATGATGGAGGAGTCTGTTGACGATGCAGCCCTCCTGGAGGAATTTGAACGGGACGTTGACCAGGCCTTTGAATTGGCTGATCAACTTACTGAGGCTGCCAAGGAGATTCTGGCTGCTCACCGGGGAGAGCCGGCTTTGAGCGGGGAAACTAAACCGACCCCGccggctttggtcacggacaGGTTGGCTGATCCTACACCGGGTCCTAGCGTGGGTCGTTCAGTGGTAGCAAGGGGACCGCCCCGGCGCCCGACCCATCAATATGCTGCTGTCCGGCAGGACAACCCCCCCGCACCGCAACAACGGTGCCGATATTGCAGAGGGGAGGGACACGATGTGCGTGCTTGCGGGAAGTTCGGTGGGCTCCGTATTGCGGGGCGGAGAGCCATCGTCAAGCAACGCGCATGGTGTTATTTGTGTTTGGGGGATCACAGACAATCAGTGTGTCCCCAAGCCAGTCATTGTGGCCACTGCGGCGGGAGGCATCACCCCCTCCTTTGTTTGAACTGCAATGGCTCTGGGAGCGATAGGGGCTCAAATTACTCGCGCCCGGAAGGGGGCCCCGCGCGCCAGGCTGGATCTCCTGAGGTTTTGTCGGGACCTATGCCTCCTCGGGGAAGACAAGGTCAGACCTCCCGGGCTGGAGGTGAATTGAGACGGGTCACCCCCCCCCCCATGGGAGGCGGGATATCTCCCCACGTGACCTTGGGTCACGTGACATAG
Protein Sequence
MPKAVKSDARIIILKVLAFMKDEKRAQQPIIPFEKLYERVAAATGVSERFLHKLVNEQKLAQECGTKIETPGKKRNRTSEEMEDEAPKIISMDESSIANSDDKRANSTSNDSKILSGRSSTSDLGLSDPCDSKVTTTSSSSDVLVTEDVDLDKTRSNDIEDNDVIIGKIDSLLENTVDDDEACSDLIDEDLKLHWDEEEETDNPDKIQAVIDAHTPTSEVFESKSPQNPKTIDLNNAAQEATVESLGNNENASNELDESNNKHAKDTIICQSSEVDTSMNLPLPHGLMKPDQMIEIPTQELIDIDDSCLLDDTSKMVAHESIEDDNLEDLEAENKHNENMQYENIENENIEDEKSVEEKLIEVAKSCDTTLLGDTITIDSSDHEENDVISIVTKKQEEKCAEIIDDTIENREPEKKISKNDETLSKSDDLTEVSLEPKVSVPGTVNSDINVQSMIGENKENCKDREDMSLEMKDEVTDLLDSNKDVNKIIGDTNEPNSPRKSDESDASNSKAPSVFSSLNPKPTISTAEELEAADTEVTEVDDSLGLLAESSRMMEDDDDEDEAEADADAEVDDDDDGDPEYDPDEDSNQVSCDQSEDSNAPQSEMEQPKDGTEVTAEDENETPSPTDENKEFDFRSIANDTAEVDDKDEMDIDMIECEEMEVPSPTNGDDTNKVTDEGQKQPKEQAPEVKTGELVEEPKTSAGSTSQDELKTSETTDESIPVKISVLETLLLDPPKPFTVSPSMSKPVGNVPSAVFNIVELEESSSEDDVQEVIKEIERTDVNIPKGIEVTASSGGSMSEIVTKEDELVISGVPKPACKKLSNMTRLNTSELTIKTCATESTLVIPETKVGKEESIKPKMGLEVFSLDSDDDENTIPEPVPSPPKPRTYKCVNPGCTNAAVLRASRSILSYYAVKTKKKRVCRSCARAVTAEQEKLVDGLLNFTPLLELDMEPPAQQLVEISDSDEEDVEDENEHNQLIGESGAKFLEAQLADMINMTWKKLNMDVRLDEVQKSLLKQMDSLQEESKEVDSMLSECQIATDKLRNELYRTFEHKRHELPAIVIFDTKPDKTDRVFGKRRMSACENPAAKRPAVPVDIENQKNTEVSVVKLCAETAPTSLPAVGEIIRPPLKIGQPVFAMRNAFGAWTKAKVMDITPPKEQHNQQFSMCRVKFEQKQTKSPFKMLSARCLAYIDPPDVRLTIGTRVIALFKNNEDLRRESYYSGVVAEIPNPVNKYRYLVFFDDGYAQYVQHQSTRLVVESSVSVWEEVHPFSRDFVRKYLLSFPERPMVRLHAGQSIKTEWNGKWWVSKVIQVDASLVQVHFEGDERVEWIYRGSTRLAPLYMELQGARGAARPARPVRRAVPRAKPAALNNQPYVEYTRSDEQNSKSAETQKAQQKQEDDIRRQRAVARKSTAVQNAPPAPTNAQGLSADSVTSRVVYYTPKNAVKPYKMSPHQCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRVKSHRACMYRAPCGRRLRNPRELHAYLTMTNSDMGVDLFDFSPNTHCLAEFVLNKCLVGKKDLSHGRENVPVPCVNYYDSTLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLGKNVGYVYRRLPEPLPSGIYECNSRCKCKNTCLNRVVQHPLQLKLQVFKTLNRGWGIRALNDVPKGSFLCIYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEDDIPEEDKELDRELERHATEFRTHMMEESVDDAALLEEFERDVDQAFELADQLTEAAKEILAAHRGEPALSGETKPTPPALVTDRLADPTPGPSVGRSVVARGPPRRPTHQYAAVRQDNPPAPQQRCRYCRGEGHDVRACGKFGGLRIAGRRAIVKQRAWCYLCLGDHRQSVCPQASHCGHCGGRHHPLLCLNCNGSGSDRGSNYSRPEGGPARQAGSPEVLSGPMPPRGRQGQTSRAGGELRRVTPPPMGGGISPHVTLGHVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-