Scau000287.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Stenodera caucasica
Gene Symbol
foxp1b
Assembly
GCA_037414795.1
Location
JAZBGZ010000009.1:97253-115572[-]

Transcription Factor Domain

TF Family
Fork_head
Domain
Fork_head domain
PFAM
PF00250
TF Group
Helix-turn-helix
Description
The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.3e-29 8.4e-27 92.8 0.3 2 81 474 547 473 554 0.94
2 2 1.3e-05 0.0082 15.9 0.0 49 82 568 596 564 601 0.87

Sequence Information

Coding Sequence
ATGGACCAGGACATAGATGGGGATGGTGCGATCAATCTTTCAACATCACAACGACCATCAGCAGCCACTACACCGATTGATAGTTTGCATACAGAAGATATCGAACAGCAAGCTGCCTCCTTGGAAAAAGTAATAAAGGAGCAACAGCAACATCAACAACTAGAACTGGAGCGAGCTTGGGACCAAGATAAAGATGCCAAAGGCAATGGCAGTACAAGTCCAAGCTCTGAACATCGTGTTCAGGATCATTCGCCCCCGCCCACCTCAGATACCCAAAAGAGCTTCACCGCCACCATTCCCCCCACCTCACAgacACAATCACATGGAGCTCAAATGATGTCATCACCTGCATCAAATTTACATCATATGCAACAACTCCTGCAACAGCACGTTTTAAATCCATCTCAATTACAAACATTAATGAAACAACAttcattattacaacaacaacaacatcagCAACATCAATTAGCCGAattaggaaaaaaacaaattgaacaaacaatgcaacaattacaagaacaattacaattgaatcTCATTCAACAAACACATATCCTGCAAAGTGcggacaaaaaaaaagcttCAGGATCTCTACAACAATTGGcacttcaacaacaacaacttatacaacaattacaattgatGCAACGACAATATGTTGTGCATCAAGGAATGGGTATGCAGCCTTTGATACTTGGTCAAGGACAAGgATTGAATGCTAGAGAAGTTATTAGTCCTTGGAAGGATATGAATGATCAgcatttaacaaataataataaatcttccGATATTAACGAGGGTTCACCTGGTTTGTTGGGGGTGGCGTCAAATCGTTCAAGTCGAGAAGAGATTCAATCCGACGATAAATTGGAACGGACGTCAACACCTGATCGAGTACATCATTTGTATGGTCATGGTGTATGTAAATGGCCAGGTTGTGAAATTATATGCGAAGATCTTCAAGCATTTATCAAacATTTAAACACAGAACACACATTAGATGATCGATCGACGGCTCAAGCACGTGTTCAAATGCAAGTTGTATCCCAATTAGAACTTCAATTACAAAAAGAACGTGATCGATTACAAGCAATGATGCATCATCTTCatttatcgaaacaattaaGTTCACCAGAACCACATAAAGATAGTGGTCCTGGTGTAACACCGCCAAAAATGTCTGTAAATGCCTCATTACCTCAACCACCTGTATCAATGGGTCCTATGGTATCTGCTGTACGATCACCTGTACTTCATTCACCAGCACCAAATGTAGGCGGACCTTTACGAAGGCGACTTACCGATAAATCAGCTTTATCATTAGCCGGAGGCTTGCCCTATATGCTTGAACGGGCAGGACTGGATGTTCAACAAgAAATTCAAAGGAATAGAGAATTTTATAAGAATGCCGATGTTAGACCTCCCTTTACATATGCCTCTTTAATTCGGCAgtCAATCATTGAATCGCCAGACAAACAGTTAACATTaaacgaaatttataattggttCCAAAACACATTTTGCTACTTTCGAAGGAATGCGGCGACATGGAAgAATGCAGTGCGCCACAACCTGTCACTCCACAAATGTTTCATGCGCGTGGAAAATGTTAAGGGTGCCGTATGGACAGTGGACGAAGTGGAATTCTACAAGAGACGTCCTCAACGTTGTTCATCAGGGCCCTTAGCCCAGCCAGTCAATGCGATACGCACCAATTTGTCACTCCACAAGTGTTTTGTACGTTATGAAGACGACTTTGGATCATTCTGGATGGTAGATGATGCTGAATTTGTGAAGCGCCGCCACTTGTCGCGTGGCCGGCCACGGAAATATGACCCAACCCCATCACCCACTCCACCCCACTGCGCACAGGGTACCACTTCAAAAAGTCCGACGTTGAATCACAGTCCGACATTATACGGTGATCATTTATCAGCGAATATTCAGttcATGCAGGCGTCTTTGATGGAtgaaaatttaccattttTAACGAGTGCCGCTTCGCTCTCGAATCGACCCAGAGATCGATCAGAATCTCCAATACATGATACTCATATAAGATCGCCAATAAATGGTGGTTTACACATTAAACAAGAAGGTATATTAAATCAGGACCATCATTCGACGCGAGAATCAGACCAAATGCATCATGTGATTAAAAGGGAGATGCATACAGAATATGATGATATAGATCAAGATCAACATACTGAAAATATGGCTGAAGACTTGACAATCCAATCGGATCATAATGATTCGAATATATTAGACGCGTAG
Protein Sequence
MDQDIDGDGAINLSTSQRPSAATTPIDSLHTEDIEQQAASLEKVIKEQQQHQQLELERAWDQDKDAKGNGSTSPSSEHRVQDHSPPPTSDTQKSFTATIPPTSQTQSHGAQMMSSPASNLHHMQQLLQQHVLNPSQLQTLMKQHSLLQQQQHQQHQLAELGKKQIEQTMQQLQEQLQLNLIQQTHILQSADKKKASGSLQQLALQQQQLIQQLQLMQRQYVVHQGMGMQPLILGQGQGLNAREVISPWKDMNDQHLTNNNKSSDINEGSPGLLGVASNRSSREEIQSDDKLERTSTPDRVHHLYGHGVCKWPGCEIICEDLQAFIKHLNTEHTLDDRSTAQARVQMQVVSQLELQLQKERDRLQAMMHHLHLSKQLSSPEPHKDSGPGVTPPKMSVNASLPQPPVSMGPMVSAVRSPVLHSPAPNVGGPLRRRLTDKSALSLAGGLPYMLERAGLDVQQEIQRNREFYKNADVRPPFTYASLIRQSIIESPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAVRHNLSLHKCFMRVENVKGAVWTVDEVEFYKRRPQRCSSGPLAQPVNAIRTNLSLHKCFVRYEDDFGSFWMVDDAEFVKRRHLSRGRPRKYDPTPSPTPPHCAQGTTSKSPTLNHSPTLYGDHLSANIQFMQASLMDENLPFLTSAASLSNRPRDRSESPIHDTHIRSPINGGLHIKQEGILNQDHHSTRESDQMHHVIKREMHTEYDDIDQDQHTENMAEDLTIQSDHNDSNILDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00277958; iTF_01329601; iTF_00814215; iTF_00813532; iTF_01022034; iTF_00929388; iTF_00841662; iTF_01566064; iTF_01283125; iTF_00639351; iTF_00852495; iTF_01567643; iTF_00870376; iTF_01409769; iTF_00414874; iTF_00752763; iTF_01277500;
90% Identity
iTF_00814215;
80% Identity
-