Scal034926.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Stenodema calcarata
Gene Symbol
Lrp5
Assembly
GCA_963920205.1
Location
OY986061.1:6338874-6348638[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.1 9.4e+03 -2.4 0.0 34 48 138 152 137 165 0.78
2 2 3.4e-11 7.8e-08 33.1 0.0 30 74 496 538 476 541 0.90

Sequence Information

Coding Sequence
ATGGCTCTTCTCCAAGACGTCATCGTTTTAGATGACTCAGAAAGTGATGACGAGCCCCAGAAAAGCTCCAGTACTTCCGGAAAATCAGAATCGCAATCAACTCCACCTGCGCCGCCCAATACAAATAATCTGAATGCTGCTAATTCTGCTTCTTCGGTTGGTGTTAGTGGCGTCCCAAGTCTCGAGGAACCTGAACTCATCGAAATTGACATTTCGGATAAGGACTCAATTGAAGATGTTGGGCAGCTTGACGCCGCAGATGGGACGCCTGATTTCCAAAAAATGCTTGACATCATTAACAAGGCTTCTGAGCAGCCACATGTCATGCATAGGAACAAAAAAGGGCCCTGGTGTTGCAATTCATGGTGTGATAAGCCAGGGTCTACAGTGCCTGGAGAGAACATACGTGACTATTACAACATACCGTCAGGAAAGACGTTTAAACTGTGCGACGATTGTGTGGAAGCGTACTACAACTACCTTGATAAAGCTGTGCGAAATCTAGAAACGGGTGGAAACATGCTTGAAGGGCGATGTTCTCGTGATAATGAATTCATTATTTTGGACAACGAGTCTGATGATGACGAAGACGTGTCTGACCCTGAGTTAGAAAAACGTCTTGGGGACGCGAACAAAGACAGCCTCCAACAACTCGACCAGCAGTACAACTTCACTGGTATCTTCAAACGAGCCAAAGACCAAGTTATTGAGGACTTGGAAAATTTCGTTATTAAGGGGAATGAGCAGGCTAGTAGAATGTCCCAAATAGAAACTGATTTTCATAAAAGCATCCAAGAGTTCAAAGGGAAGTTCAAGAATGAAAAAACTGTTTCAGAGGGAGAGCTGATCATTCCATTTCACGTTGGAGTTAGCGTTCAGAAGCAGAAAACGCTTGAGAAATTTGGTGGAGATTACGCTGAGTTGGGTGATGTCAGGGAGGAAGAATCCAATGGGCTGCCTCCGTTTGGCGATCTAGTGAGACCCCCTCCGAAAGTTGGTGATCTCGTTTACGCTATGAGAGAAGGCAACTATTCAGAATGGATCCCTTTCAAAGTTGTGGACGTCATCTACGATTCGGACGAACAGGGAAATTTCTTTGAAACCTTCAGTTTGCAAACTGTCGCTAATGGTGTGATTGTGAAGAAAGTCGTTAATGGTGATCATTTGGCTTTCAGCGAAGTTCCCAATGTGCGGCTGGGAATCGGCAGCCGTATAATTGGTGCTTGTAACCAAACTACGAACGTCAGAGGTTCAAAGAGTTTCCATTCTGGCATGGTAGCTGAACTTCCAACACACATGAACCAGTTCCGTTATTTAGTATTTTTTGACAACGGGAAAGCGCAATATTGTCCTCATGATGACCTAAAAGTAGTTTACAAACCGATGAAGAAAATTCACGAGGTCAAATATGCAGAAGAAAAAACCAAAGGCGCCAATCCATTGGCCATCCCTTCAATTTTCGCATTCAAGAGGGAAATCGACGTGACAAGCGCTGTGACATACACCGCGCCTTGTGGTAAAAGGTTGAAAAACATTCAAGAAGTTCTCAAGTATTTATCTGAAACGCTCATCCCTCTAACATTGGACATGTTTGACTTTGACATCAGGACTATGATATTTGACGTGTACATAGTGGCACCTCAGTTCACGATCATGGAAGATATAAGTTTTGGAGCTGAAAGAAATCCAGTTGCATGTGTCAATGAAGTTGATATGGACTGCCCCGATTTGATGCAGTACATGACAGAAAGGCGGCCACTTGAAGGTGTCAATATAAATTTGGATCCTGACTTCCTCGTTTGCTGTGACTGTGAAGACAACTGTCGAGACCGCTCCAAGTGTCGTTGCTGGAGGCTAacgattgataatttcaagccATTTAACCAAGGCGTCGAGCTCAAAAGCAATGGAAGAACCCGCGTCGCGCCTGAGGCTTTTTTGTTGTTCACGAGGAAAGACAACATCGGTCGCATCAGCATAAAAAACGCACATAACGACGCCATAATACCCGCATCAGGAGTCAAAGATGCCAGTGCTTTGGATTTCGACATACGAGAAAGTAGAATATATTGGACGGACGTGAAAGCTAAGGCTATAACAAAGGCGTACCTTGATGGGTCTAACGTGGAAAAAATCATCGAATACGGTCTAGACTCACCTGAAGGGCTTGCAGTGGACTGGGTGTCACACAATATTTACTGGACGGACACGGGGACCAAGAGGATCGAAGTGGCGAGAGTAGATGAAAAATACAGACGACCAGTGTTATGGAGGGGGATTCACGATCCTAGAAGCATAGCCGTCGATCCGAACCGAGAGTTCATTTATTGGAGTGACTGGGCAGGCTCGGGATCTCTTCACAGAGCCCGACTGAACGGTAACAATCCCAAAGCCCTCATACCGAAATTGGGGCGAGTGAAGTCTCTAACGATCGATCTCTTAGAAGGCGTCGAGCTCGAAAGCAATGGAAGAACCTGCGTCGCGCCTGAGGCTTTTTTGTTGTTCACGAGAAAAGACAACATCGGTCGCATAGAAAACGCACATAACGACGCCATAATACCCGCATCAGGAGTTAAAGATGCCAGTGCTTTGGATTTCGACATACGAGAAAGTAGAATATATTGGACGGACGTGAAAGCTAAGGCGTACGTTGATGGGTCAAACGTGGAAAAAATCATCGAATACGGTCTAGACTCACCTGAAGGGCTTGCAGTGGACTGGGTGTCACACAATATTTACTGGACGGACACGGGGACCAAGAGGATCGAAGTGGCGAGAGTAGATGGAAAATACAGACGACCAGTGTTATGGAGGGGGATTCACGATCCTAGAAGCATAGCCGTCGATCCGAACCGAGAGTTCATTTATTGGAGTGACTGGGCAGGCTCGGGATCTCTTCACAGAGCCCGACTGAACGGTAACAATCCCAAAGCCCTCATACCGAAATTGGGGCGAGTGAAGTCTCTAACGATCGATCTCTTAGAAGGCGTCGAGCTCGAAAGCAATGGAAGAACCTGCGTCGCGCCTGAGGCTTTTTTGTTGTTCACGAGAAAAGACAACATCGGTCGCATCAGCATAGAAAACGCACATAACGACGCCATAATACCCGCATCAGGAGTCAAAGATGCCAGTGCTTTGGATTTCGACATACGAGAAAGTAGAATATATTGGACGGACGTGAAAGCTAAGGCTATAACAAAGGCGTACCTTGATGGGTCTAACGTGGAAAAAATCATCGAATACGGTCTAGACTCACCTGAAGGGCTTGCAGTGGACTGGGTGTCACACAATATTTACTGGACGGACACGGGGACCAAGAGGATCGAAGTGGCGAGAGTAGATGGAAAATACAGACGACCAGTGTTATGGAGGGGGATTCACGATCCTAGAAGCATAGCCGTCGATCCGAACCGAGAGTTCATTTATTGGAGTGACTGGGCAGGCTCGGGATCTCTTCACAGAGCCCGACTGAACGGTAACAATCCCAAAGCCCTCATACCGAAATTGGGGCGAGTGAAGTCTCTAACGATCGATCTCTTAGAAGAAGAGGTCGTAAAGAGTATTCAAATAGTTGAATGCAACCCGAAAACTGAAGGCGATTAA
Protein Sequence
MALLQDVIVLDDSESDDEPQKSSSTSGKSESQSTPPAPPNTNNLNAANSASSVGVSGVPSLEEPELIEIDISDKDSIEDVGQLDAADGTPDFQKMLDIINKASEQPHVMHRNKKGPWCCNSWCDKPGSTVPGENIRDYYNIPSGKTFKLCDDCVEAYYNYLDKAVRNLETGGNMLEGRCSRDNEFIILDNESDDDEDVSDPELEKRLGDANKDSLQQLDQQYNFTGIFKRAKDQVIEDLENFVIKGNEQASRMSQIETDFHKSIQEFKGKFKNEKTVSEGELIIPFHVGVSVQKQKTLEKFGGDYAELGDVREEESNGLPPFGDLVRPPPKVGDLVYAMREGNYSEWIPFKVVDVIYDSDEQGNFFETFSLQTVANGVIVKKVVNGDHLAFSEVPNVRLGIGSRIIGACNQTTNVRGSKSFHSGMVAELPTHMNQFRYLVFFDNGKAQYCPHDDLKVVYKPMKKIHEVKYAEEKTKGANPLAIPSIFAFKREIDVTSAVTYTAPCGKRLKNIQEVLKYLSETLIPLTLDMFDFDIRTMIFDVYIVAPQFTIMEDISFGAERNPVACVNEVDMDCPDLMQYMTERRPLEGVNINLDPDFLVCCDCEDNCRDRSKCRCWRLTIDNFKPFNQGVELKSNGRTRVAPEAFLLFTRKDNIGRISIKNAHNDAIIPASGVKDASALDFDIRESRIYWTDVKAKAITKAYLDGSNVEKIIEYGLDSPEGLAVDWVSHNIYWTDTGTKRIEVARVDEKYRRPVLWRGIHDPRSIAVDPNREFIYWSDWAGSGSLHRARLNGNNPKALIPKLGRVKSLTIDLLEGVELESNGRTCVAPEAFLLFTRKDNIGRIENAHNDAIIPASGVKDASALDFDIRESRIYWTDVKAKAYVDGSNVEKIIEYGLDSPEGLAVDWVSHNIYWTDTGTKRIEVARVDGKYRRPVLWRGIHDPRSIAVDPNREFIYWSDWAGSGSLHRARLNGNNPKALIPKLGRVKSLTIDLLEGVELESNGRTCVAPEAFLLFTRKDNIGRISIENAHNDAIIPASGVKDASALDFDIRESRIYWTDVKAKAITKAYLDGSNVEKIIEYGLDSPEGLAVDWVSHNIYWTDTGTKRIEVARVDGKYRRPVLWRGIHDPRSIAVDPNREFIYWSDWAGSGSLHRARLNGNNPKALIPKLGRVKSLTIDLLEEEVVKSIQIVECNPKTEGD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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