Basic Information

Insect: Stegana nigrithorax
Gene Symbol: ftz-f1
Assembly: GCA_037044495.1
Location: JBAMBQ010003786.1:106104-119171[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.083 5.3e+02 -0.2 10.5 61 133 102 171 96 177 0.76

2 3 1.9e-19 1.2e-15 58.0 0.6 1 76 330 406 330 436 0.66

3 3 5.4e-72 3.5e-68 231.0 1.7 158 408 515 758 488 760 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.083	5.3e+02	-0.2	10.5	61	133	102	171	96	177	0.76
2	3	1.9e-19	1.2e-15	58.0	0.6	1	76	330	406	330	436	0.66
3	3	5.4e-72	3.5e-68	231.0	1.7	158	408	515	758	488	760	0.92

Sequence Information

Coding Sequence: atgttattagaAATGGAGCAGCAACAGGGGACCGTATCCTTTATATCGTCACTAAACATGTCCCCATTCTCAATGCAATTggagcagcagccagccagtccGGCGTTGGCGGGCAATCAGCAGAGCGGTGGTGGCACTGGTGGCAACAACGCGAataatgtcaacaacaacagcagcaacaacaacaatgataatgaCACAAACCCTCTAAGCAATTCCGATGCAGATTACAGCGCCTACACGTTGCAATTAGCAGGAGGCAGCAACAGTGGAGGCGGCGGCAGCGGAGGTGGCGGCGGCGTCAGCACCAGCAATcagcaccaccagcagcaacaccaccaccatcaccaccaacagccgcagcagcaccagcaacagcagcagcactatcagcagcaacagcagcaacaacagcaaaatattgCGAACAATTCAAATTTCTCATACTCGTACATTTACAATTTCGACTCACAGTACATATTCCCGACAGGCTATCAGGACACCACCTCGTCGCACTCACAGCAGAGCGgaggtggcggcggcggcggcagtggcggTGGCTCAGGCCTGAACGCGCAGCTGCTGAACGGCGCTGGCGGCGGCGGTATTGGCGGCAACTCAGGCAATACAGCCGCCGGTGGCTACATGTCATTGCTACCGCCAGCCAGCGGTGCAGGAGCGCATCTCGGTGGCGCCGGTGTCGCTGGTAGCGGCGGCACTAGCGCCACATCCGGTGTCTCCGGTGAGGCTATTGATTTCAAGCATCTCTTCGAGGAGCTATGTCCCGTGTGCGGCGACAAGGTCAGCGGCTATCACTACGGCCTGCTGACGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGAACAGTACAAAACAAGAAGGTCTACACCTGCGTGGCTGAACGATCGTGTCACATCGATAAGACGCAACGCAAACGTTGTCCTTATTGCAGATTCCAGAAGTGTTTAGAAGTTGGCATGAAACTTGAAGCTGTCAGAGCAGACCGCATGCGCGGCGGCAGGAATAAGTTCGGACCCATGTATAAACGCGACCGGGCGCGAAAGCTGCAAGTGATGCGTCAGCGTCAGTTAGCGCTGCAGGCGCTACGCACCACAATGGGATCTACGGACATGAAGCCGACGCCATTGTCGCCGGGCTATCAGCAAGCATATCCAAACATGAATATTAAGCAGGAAATACAAATACCTCAGGTATCCTCACTCACACAGTCACCAGATTCGTCTCCCAGCCCTATTGCAATCGCACTGGGTCAGGTCAACACCGGTTCGGGTGTGATAGCGACGCCGATGAATGGCAATGGCGGCACCACCGCTGGCGGTGCCACTGGAGGCGGTGGCAATGGCAGTGGAGGTGGAGGTggaggcggcggcggtggtggaggcaacaacaacagtaacaacaacagcaacaacagcgacatcATCAATCGCGGTAGTGGCAGCAGTTGTCACGATGCCGGAACTGGATCTCTGCAGAATATAGCTGAATCGAAATTGTGCTTCGATTCCGGCACGCATCCTTCGAGCACCGCCGACTCGCTCATCGAGCCTCTGAGGGTATCACCGATGATCCGCGACTTTGTGCAATCCATCGATGACAGGGAATGGCAGACGCAGCTGTTTGCGCTGCTTCAGAAGCAGACGTACAATCAGGTCGAAGTGGATCTGTTCGAGCTAATGTGCAAAGTGCTCGATCAGAATTTGTTCTCTCAGGTCGATTGGGCAAGGAACACGGTCTTCTTCAAGGATCTTAAGGTCGACGATCAGATGAAACTCTTGCAGCACTCCTGGTCCGATATGCTTGTGCTGgatcatcttcatcatcgaATACACAATGGCCTGCCTGATGAGACGCAGCTCAATAATGGTCAggtgtttaatttattaagtttgGGTCTGTTGGGCGTGCCACAATTGGCAGATTACTTTAATGAGTTGCAGAGCAAGCTGCAGGATCTGAAATTCGACATGGGCGattatgtgtgtatgaaattCCTAATATTGTTAAATCCAGAAGTGCGTGGCATTATCAACAAGAAAACGGTCTTGGAGGGACACGAGAATGTGCAGGCAGCGCTACTGGACTACACGCTCACTTGTTACCCTTCAGTGACGGATAAATTCAGGCGGCTCTTGAATATTCTACCTGAAATACACGCCATGGCTGCGCGCGGTGAAGAGCATCTGTACTCAAAGCACTGCGCCGGCAGTGCGCCCACACAAACGCTTCTCATGGAAATGCTGCATGCCAAGCGTAAAGTGTAA
Protein Sequence: MLLEMEQQQGTVSFISSLNMSPFSMQLEQQPASPALAGNQQSGGGTGGNNANNVNNNSSNNNNDNDTNPLSNSDADYSAYTLQLAGGSNSGGGGSGGGGGVSTSNQHHQQQHHHHHHQQPQQHQQQQQHYQQQQQQQQQNIANNSNFSYSYIYNFDSQYIFPTGYQDTTSSHSQQSGGGGGGGSGGGSGLNAQLLNGAGGGGIGGNSGNTAAGGYMSLLPPASGAGAHLGGAGVAGSGGTSATSGVSGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRTTMGSTDMKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNTGSGVIATPMNGNGGTTAGGATGGGGNGSGGGGGGGGGGGGNNNSNNNSNNSDIINRGSGSSCHDAGTGSLQNIAESKLCFDSGTHPSSTADSLIEPLRVSPMIRDFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLADYFNELQSKLQDLKFDMGDYVCMKFLILLNPEVRGIINKKTVLEGHENVQAALLDYTLTCYPSVTDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01363997;
90% Identity: iTF_01363997;
80% Identity: iTF_01363997;