Ssim012458.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Spicauda simplicius
Gene Symbol
br
Assembly
GCA_949699795.1
Location
OX453065.1:20921497-20931431[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.8e-29 1.5e-26 93.5 0.1 1 100 22 117 22 121 0.95

Sequence Information

Coding Sequence
ATGGTGGACACACAGCACTTCTGTTTGCGGTGGAACAACTACCAGAGCAGCATCACCAGCGCCTTCGAGAACCTTCGTGATGACGAGGATTTCGTGGACGTGACGCTCGCCTGTGACGGCAAAAGCCTCAAAGCCCATAGAGTGGTCTTATCAGCCTGTAGCCCGTACTTCCGAGAGCTACTAAAATCAACGCCATGCAAGCACCCAGTAATAGTACTCCAGGACGTGGCGTTCACGGATCTGCACGCGCTGGTGGAGTTCATCTACCACGGAGAGGTGAACGTGCACCAGCGGTCCCTCTCCTCCTTCCTCAAGACCGCTGAGGTGCTCCGCGTGTCCGGCCTCACGCAGAACGACGACGCCCAAGGGCCGCTAGTGCAGAGCatcgcgcgcgccgccgccgccgccgcgtcGTCGCCGCACACGCCGCCGCACCCCGTGCACACGCCCCACACGCCGCACACGCCCAACTACAACGAGAAGCTCGAGGAGGCTCTGCTCAACCACCCTCCACCCATGATGCGGCGCATCCCACTGCCGCCCCGCCGCATGAGCCGCTCCGCCGACAACTCCCCTGACGTCATCAAGCGCACACGCCACGATAACAACAACGACCAACCCCAGATCCACGACTTCTCCACCAAGAACCACTCGCTGAACAACTCGCGCGCGCACACCGAACAGGGCAACAACGGCAACGGTATCTCCAACAGCAGCTCCTCGCCCTCGCCCCGCCTCATGGAGGAGGTCAAGAACGAACCTCTCGATATGATCTGCCCATCCAACCCGGACATCGACAGGAGCACCGACGACACGCCGCCGCATCCTCATCATAGAGCACTTGGAGGCGGCCCGCCATCTCGCGGCAGCTCTGCCGACGCCGACGACCGCACCCCGCCGCCGCAGCTGCCGCCCTCGCCGTTCATCCCGCCACCTGATGCCAAGCTCTTCGCTCCCTCTAACGCTCACTACAACTTCAACATATCGGCTCTTGCTGATCCCTCTGCTTTAGCCGGTCTGCCGAGCCCGCTGGCACCCGATGGCATGGCGAGCACCTCTCAAGTGGGCCCCTTGGGGGCGGGTCACCGATGCGAGGTGTGCGGGAAGCTGCTGTCGACGCGGCTGACGCTCAAGAGGCATACGGAGCAGCAGCACCTGCAGCCGCTGCATTCGGCGCGCTGCAGCCTCTGCCACAAGGTGTTCCGCACGCTCAACTCGCTCAACAACCATAAGAGCATCTACCACCGGCGCCAGCGCGGCCTGCCGCAGCAGACGCAGCCGCAGAACCTCACCACCAGCCCCGACACTAAGATCGCTCCGCCGCACCACAACATCGACTTCTACAAGTTCAAAGATCAGTTCAATGTCTAA
Protein Sequence
MVDTQHFCLRWNNYQSSITSAFENLRDDEDFVDVTLACDGKSLKAHRVVLSACSPYFRELLKSTPCKHPVIVLQDVAFTDLHALVEFIYHGEVNVHQRSLSSFLKTAEVLRVSGLTQNDDAQGPLVQSIARAAAAAASSPHTPPHPVHTPHTPHTPNYNEKLEEALLNHPPPMMRRIPLPPRRMSRSADNSPDVIKRTRHDNNNDQPQIHDFSTKNHSLNNSRAHTEQGNNGNGISNSSSSPSPRLMEEVKNEPLDMICPSNPDIDRSTDDTPPHPHHRALGGGPPSRGSSADADDRTPPPQLPPSPFIPPPDAKLFAPSNAHYNFNISALADPSALAGLPSPLAPDGMASTSQVGPLGAGHRCEVCGKLLSTRLTLKRHTEQQHLQPLHSARCSLCHKVFRTLNSLNNHKSIYHRRQRGLPQQTQPQNLTTSPDTKIAPPHHNIDFYKFKDQFNV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00204450; iTF_00878946; iTF_01080834; iTF_01507335; iTF_01506472; iTF_01079166; iTF_00843652; iTF_00824870; iTF_01080009; iTF_00642479; iTF_00796627; iTF_00986358; iTF_01508182; iTF_00695801; iTF_00674403; iTF_00994458; iTF_00355324; iTF_01090909; iTF_00171968; iTF_00356416; iTF_00063716; iTF_00673605; iTF_00467498; iTF_00468273; iTF_01416010; iTF_01416962; iTF_01251956; iTF_01083480; iTF_00761853; iTF_00115051; iTF_00771181; iTF_01437259; iTF_00007297; iTF_01157964; iTF_01155489; iTF_00027885; iTF_00876301; iTF_01202574; iTF_00025327; iTF_00948015; iTF_01017839; iTF_00419078; iTF_00420643; iTF_00421467; iTF_00430769; iTF_00648241; iTF_00205298; iTF_01021417; iTF_00844498; iTF_01336995; iTF_01125587; iTF_01279397; iTF_00074662; iTF_00035848; iTF_00382792; iTF_01282472; iTF_00076684; iTF_01281453; iTF_00075662; iTF_01335119; iTF_00006384; iTF_00681744; iTF_00683474; iTF_01081715; iTF_00034904; iTF_00682552; iTF_00408569; iTF_01280508; iTF_01334012; iTF_00279229; iTF_00284669; iTF_00752189; iTF_01331806; iTF_01203347; iTF_01205011; iTF_01205811; iTF_01220756; iTF_00651871; iTF_00724053; iTF_00146550; iTF_00072945; iTF_00720470; iTF_00197462; iTF_00448311; iTF_00621335; iTF_01018689; iTF_00775363; iTF_00776112; iTF_00778101; iTF_00781126; iTF_00776840; iTF_00457334; iTF_00778839; iTF_00779639; iTF_00458168; iTF_00774587; iTF_00781935; iTF_01181983; iTF_00806839; iTF_00833271; iTF_01204183; iTF_01206680; iTF_00213656; iTF_01426072; iTF_00144761; iTF_00347577; iTF_00365045; iTF_01504006; iTF_01503097; iTF_00782745; iTF_01082585; iTF_00795822; iTF_01439150; iTF_01438146; iTF_00887507; iTF_00971478; iTF_00970518; iTF_00922971; iTF_01071739; iTF_00212669; iTF_00159966; iTF_00859614; iTF_01358979; iTF_00819295; iTF_00247327; iTF_00248228; iTF_01153119; iTF_00195264; iTF_00288160; iTF_00961056;
90% Identity
iTF_00288160;
80% Identity
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