Spin019218.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Sphinx pinastri
Gene Symbol
-
Assembly
GCA_947568825.1
Location
OX387616.1:4614566-4623742[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.092 7.5 7.8 1.5 1 23 232 254 232 254 0.96
2 16 0.13 11 7.3 0.0 2 23 283 305 282 305 0.93
3 16 0.0059 0.48 11.6 0.3 2 23 326 348 325 348 0.95
4 16 0.00041 0.033 15.2 2.2 2 23 354 376 353 376 0.95
5 16 0.0012 0.1 13.7 1.5 1 23 381 404 381 404 0.96
6 16 0.49 40 5.5 0.1 2 23 407 429 406 429 0.93
7 16 0.0015 0.13 13.4 1.0 2 22 436 456 435 456 0.93
8 16 0.0043 0.35 12.0 0.3 1 23 517 540 517 540 0.93
9 16 0.15 13 7.1 0.0 3 23 569 590 567 590 0.94
10 16 0.038 3.1 9.1 0.2 3 23 614 636 612 636 0.94
11 16 0.00048 0.039 15.0 0.4 3 20 643 660 641 664 0.90
12 16 0.013 1 10.5 0.3 1 23 669 692 669 692 0.97
13 16 0.00098 0.08 14.0 0.3 2 23 698 720 698 720 0.92
14 16 0.00012 0.0098 16.9 4.8 1 23 724 747 724 747 0.97
15 16 0.00035 0.029 15.4 1.8 2 23 754 775 753 775 0.96
16 16 0.0047 0.39 11.9 2.3 1 23 781 803 781 803 0.97

Sequence Information

Coding Sequence
ATGGAGTTTGATGAGATAGTTGTGAAGGAGAGCCCGGGATTGTGCCGGTGCTGTCTTTCCGAAGGATGCTACAAAGACCTCGGCTCGGAGTACACTTGGATGAACGACAATGAAATATATGCTGATATGTTGTTGGAATGCTTTGATATTAGTATAACACAACACAATGATGGTCCCAATGGTCCCAACCGACTAATATGTGAGGTGTGCATCACCAGGCTGCGGGATGCTTGCAACTTTAAAAAACAGGTGCTGGAGTCGGAAAAGAAATTCATTGATATGGTGGCACGGGGAGACTTTAGGCCTAAAGTACTGATGTACCAGACGCAGATGAAATCAGAAGAAAATGTTGAAGAAGTAATTGTTGAGGAGATTGAATATCTTGATGATGAAACAGAGTTTGGGGATGATGAACCACTCAAACGTGAGGATCCATCAGTGTCTGAGATAACAGTTGAGCCATTACCGGTGAAAGGCAAGCGCGGCAGGCCCCGCAAGAATGCAGACGTCAAGACTGAGAAACGGATCAAAGTCGCCAAGACCGAGGAGAAGGCGAAAGCATCTAAAGCTGTTGCAAAAGATGATAAACCGAGAAAATACAGGGGGTGTGAATCATCATCGATGCGCAGACGGAAAAACCTTCAAATACTTTTCAACAGCACCTCTATCATACCATTTAAATGGCGCGGCAAGTACTTATGTTTCTACTGCAGCAAGGATATCTCGGAATACACCGAGCTCAGGAATCACACCAAGTCGCACGGCAGCTGCTCTATCCGGGATCATTCCCTAAAGGTCCTCAAAGGAGGGCAGAATATGGAGATTAAGATTGATGTGTCTGATGTAACTTGTGAGATTTGCAGCGAGCCTTTCCCTTCATTCGAAGAGATTTTAAACCATTTATACGTGAAACACAAACTTGAGTATGACAGAGGAGTGGAAATGGCTATTGAAGAGTACAAGCTGATGGATCTTAGCTGTTTGTTGTGTGGTGAAAAGTTTACATACTTTGGCTACTTGGTATCTCACGTTAATAGTACGCATCCAAAGAATTGCCTTGTATGCGATAAATGTAATCAAAAGTTTAACAAGAAACGGGACCTTTTCTCCCACATCAAGAATTATCACAGGGAAGGCGGATACAAATGCGAGATGTGTCCTCAGACATTTAGTTCATTGAACATATTGAGAAAACACAGAAATAATAGACACTTGACTCGGTGCAATATTTGCCAGTTGAAACTCCCCTCAGCTGCGTTGAAACAAAAACACATAGAACTAGAACATCCAGATGATGGGTCATTACAATGTGATAACTGTGATAAAGAGTTTCATACGAAGCAAGGATTGAAAATGCACGCAAGGAAATGCAAAGGCGAGAACGAGATTTTAGATTTTGCCTTCAAGAAAGAAGATTATGTAGCAATGGATTTAGATCAGAACTACGAAGACCGTTCAAACCGGCCTAGCGTAAAGCAAATTCGAGAAAACATCGTCATTGTAATCAACATGTCAACGGCAATACCCTTTAACTTTTACAAGAACAAGTTTAATTGTTTCTACTGCTCGAAGGATTTTCCCGACTCGGATGCGATGCGAGAACATACAGTAATGGAACATCCAGTTTGTGATGTTAAACAAAAATGTATAAGAAAGTGTAGGGAATCGGTAGCGTGCGTTAAAATTGACGTATCCTCCCTAGCTTGTAAGATCTGCTTTGAGGCTATGACTGATTTAGATAATTTGCTCGATCATCTCATTGTTAAACATGAAGCTAATTATGACAAATCAATTACGACTTGTTTACAACCCTACAGTTTGATTAAAGATCATATGGCTTGCCCCAATTGTCCGGGTGAAGTGTTTCGATTCTTCGGCACTTTACTAAAGCACATGAACAAAAAACATACTAACAATAATATTATTTGTGTGTATTGTGGAGAGACTTTTAGGCGTGACCAAAACTTAAGAGTACATATATGGAGGCATCATAGGGACGGCCGGTTCAAATGTAGCATATGCGGAGCAGAATGTAATATCCCTTCTAGGTTGTACATGCATATGGCAAAAGCTCATGGTGTCAGAGCGGCCAAATGTCCCAAGTGCCCAGAACGGTTCGCCACCCAGTACTTGAGGCAAAAGCATTTAATAGACGTTCACGATTCTGGACACAAATGTACATATTGTGGTaaactgttcactaggaactcgtttatgagagatcacgtacggcggacgcatttaaaggagaagaacgttgaatgttcaatatgtcacatgaagttttttaataatatactgttgaggcggcacatggtgaagcacagtggtgaaaagaacttccattgcgatgtttgcggggagagattcttttggcggaagagtctcaggacgcatatgGCCAGGCATAGCAAACATGTTATTCCGGTACAACTATAG
Protein Sequence
MEFDEIVVKESPGLCRCCLSEGCYKDLGSEYTWMNDNEIYADMLLECFDISITQHNDGPNGPNRLICEVCITRLRDACNFKKQVLESEKKFIDMVARGDFRPKVLMYQTQMKSEENVEEVIVEEIEYLDDETEFGDDEPLKREDPSVSEITVEPLPVKGKRGRPRKNADVKTEKRIKVAKTEEKAKASKAVAKDDKPRKYRGCESSSMRRRKNLQILFNSTSIIPFKWRGKYLCFYCSKDISEYTELRNHTKSHGSCSIRDHSLKVLKGGQNMEIKIDVSDVTCEICSEPFPSFEEILNHLYVKHKLEYDRGVEMAIEEYKLMDLSCLLCGEKFTYFGYLVSHVNSTHPKNCLVCDKCNQKFNKKRDLFSHIKNYHREGGYKCEMCPQTFSSLNILRKHRNNRHLTRCNICQLKLPSAALKQKHIELEHPDDGSLQCDNCDKEFHTKQGLKMHARKCKGENEILDFAFKKEDYVAMDLDQNYEDRSNRPSVKQIRENIVIVINMSTAIPFNFYKNKFNCFYCSKDFPDSDAMREHTVMEHPVCDVKQKCIRKCRESVACVKIDVSSLACKICFEAMTDLDNLLDHLIVKHEANYDKSITTCLQPYSLIKDHMACPNCPGEVFRFFGTLLKHMNKKHTNNNIICVYCGETFRRDQNLRVHIWRHHRDGRFKCSICGAECNIPSRLYMHMAKAHGVRAAKCPKCPERFATQYLRQKHLIDVHDSGHKCTYCGKLFTRNSFMRDHVRRTHLKEKNVECSICHMKFFNNILLRRHMVKHSGEKNFHCDVCGERFFWRKSLRTHMARHSKHVIPVQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00013343;
90% Identity
iTF_00063808;
80% Identity
-