Spin006197.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Sphinx pinastri
Gene Symbol
-
Assembly
GCA_947568825.1
Location
OX387622.1:13274149-13292081[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 8.2e-05 0.0067 17.4 2.2 1 23 436 458 436 458 0.97
2 20 0.0043 0.35 12.0 0.6 1 20 464 483 464 486 0.94
3 20 8.1e-05 0.0067 17.4 4.4 1 23 505 527 505 527 0.97
4 20 0.0001 0.0082 17.2 4.1 1 23 533 555 533 555 0.99
5 20 3.8e-05 0.0031 18.5 5.3 1 23 561 583 561 583 0.97
6 20 1.2e-05 0.00096 20.1 7.3 1 23 589 611 589 611 0.97
7 20 7.7e-07 6.3e-05 23.8 2.8 1 23 617 639 617 639 0.97
8 20 0.0001 0.0085 17.1 6.7 1 23 645 667 645 667 0.97
9 20 0.0001 0.0085 17.1 6.5 1 23 673 695 673 695 0.97
10 20 5e-07 4.1e-05 24.4 1.9 1 23 701 723 701 723 0.98
11 20 5.1e-05 0.0042 18.1 7.9 1 23 729 751 729 751 0.98
12 20 3.6e-06 0.00029 21.7 7.6 1 23 757 779 757 779 0.98
13 20 1e-05 0.00085 20.3 4.4 1 23 785 807 785 807 0.98
14 20 8.4e-06 0.00069 20.5 5.2 1 23 813 835 813 835 0.96
15 20 7.6e-06 0.00062 20.7 7.2 1 23 841 863 841 863 0.97
16 20 3.1e-06 0.00026 21.9 6.0 1 23 869 891 869 891 0.98
17 20 1.7e-05 0.0014 19.6 8.0 1 23 897 919 897 919 0.97
18 20 2.5e-06 0.00021 22.2 4.1 1 23 925 947 925 947 0.96
19 20 0.00056 0.046 14.8 0.3 1 23 954 976 954 976 0.96
20 20 0.26 21 6.4 5.6 1 23 983 1005 983 1005 0.99

Sequence Information

Coding Sequence
ATGAATCCCGAACATCATAATATAAATACGGGTGGTGGCCAGCCTCCGGGAAGTACAGAGTCTCAGAATCAAAGAGTTCAATCCGCACAGCAAAAGCAGCAAAGTAATTTGACGCCCACTACGTCTGCTACTGACCTGCGAGTGAACTCGGCTGCCGTCAACGTTGCTTTGTCTAGCGTCGCAAAATATTGGGTGTTTACAAATTTATTCCCTGGGCCGATACCACAAGTTTCCGTTTACGGATTACCTACAGGCACAAGGATTGAAAATGGAAAACCTGTCCAGGATCTCGGACAGGCACATGCAAGCATACTCAATGGTGATCCGAACATACTATTAGGACATCATGGGGCACAGCCACAAGTTACTGTTTCTGCATCAGGAGCTCAACAGATACCTGTGTCGCAAATTATAGCTACACAGTCTGGGCAAACGCATGAAGCACTTGTGGGTCACAGCCAAGCGCAGGAGATGGGTGCGGGCGGCGGCGCGGGCGCGGCGGTGGGCGCTCCGCACGCCTCGCACTCTGCGCACGCGCCGCACGCCACGCACGCCACTCACGCGCATCACCAGGTACCCAATAACCGGGTCGAGTTTGTTCAACACCATAACATTGATATGGGACATCATTCACAGCAACACAATATGATGCAACAACAACTAATGGCTACATCGCGACAGGATCATCCAAATCAACAAATTCAATTAACGGTCAGCGAAGACGGCATAGTGACGGTAGTGGAACCCGGCGGTGGCAAAATGGTGGACAAAGAGGAATTACACGAAGCAATAAAGATACCAAGTGACCATGCACTTACTGTGCATCAGTTGCAGCAGATAGTTGGCCAACAGGTAATCGACAGCGTGGTCCGCATCGAGCAGGCGACGGGCGAGCCCGCCAACATCCTGGTGACGCACAACGCGGACGGCACCACCTCCATCGAGGCCAGCGCCGCCGACCACGCGCCGCTCGTCAAGGACGAGAACAAGCAGCCCAAGATCGATGCGCAGTTCGCCATACCCGCCGAGATCAAGGATATCAAGGGCATCGATTTGAAGACTGTAGGAGCCATGGGAATGGAAGGCGCAGTGGTCAAGATATCGGCCGGAGCCTCGGAGCACGACATGCACGCAATGTATAAAGTTAACGTCGAAGATCTGTCACAACTGTTGGCGTATCATGAAGTGTTTGGAAAATTAAATTCAGAAGGACAACCGCAGCAACAGGCGAAGGTAATCAGCGAAGTGGAAGTAGAGCCGGGAACGAGCGCCGCCATGTCAGAGCCTGAATCGTCGCCGGGACACCATTCGTGTGACATTTGTGGGAAAATATTCCAGTTTCGATATCAGCTGATCGTACACAGACGGTACCACGGCGAAAGCAAGCCATTCACGTGTCAAGTGTGCGGCTCCGCGTTCGCGAACCCCGTCGAGTTGTCAAGACACGGAAAATGTCACCTTGCCGGCGATCCATCAGAAAGACACACCAAAAGGTTGACGCAAGACAAACCATATGCATGCACTGCTTGCCACAAAACATTCTCAAGGAAAGAACATCTCGACAACCACGTGAGAAGTCATACTGGAGAGACGCCATACAGATGCGAGTTCTGCGCAAAAACATTCACGCGGAAGGAGCACATGGTGAACCACGTGCGGAAACACACGGGAGAGACACCTCACCGCTGCGATATCTGCAAGAAGAGCTTCACACGGAAGGAGCACTTTATGAACCATGTCATGTGGCATACAGGTGAAACGCCGCACCATTGTCAAATATGCGGAAAGAAGTATACTAGGAAGGAGCATTTAGTGAACCACATGAGATCACACACGAACGATACACCTTTTCGATGTGATCTATGCGGCAAGTCGTTTACAAGGAAGGAACACTTCAACAATCACATATTGTGGCATACGGGCGAAACACCGCATCGTTGCGACTTTTGTTCGAAAACGTTCACACGTAAAGAGCATCTGCTAAATCACGTCAGACAACACACGGGGGAGTCTCCGCACCGGTGTAACTTCTGTTCGAAATCGTTCACGAGGAGAGAGCATCTCGTGAACCACGTGCGGCAACATACAGGAGAAACACCATTCCAGTGCGGATACTGCCCGAAAGCTTTCACCAGGAAGGATCATCTTGTGAACCACGTGAGACAGCACACAGGCGAGTCGCCGCACAAGTGTTCGTTCTGCACGAAGTCATTCACGCGCAAGGAGCACCTCACGAACCACGTGCGGCAACACACCGGCGAGTCGCCGCACCGCTGCACCTACTGCTCCAAGTCCTTCACACGCAAGGAGCATCTCACCAACCATATCAGACAACACACGGGCGAAACACCACACAAGTGCACGTTCTGCCCGCGGGCCTTCGCGCGCAAGGAACACCTCAACAACCACATCCGACAACACACCGGCGTCACGCCGCACGCCTGCTCCTACTGCAGCAAGACCTTCACCAGGAAGGAACACCTCGTCAACCACATCAGACAACACACGGGCGAGACGCCGTTTAAATGCACGTACTGCTCAAAGTCATTCTCACGCAAAGAACACCTGACTAATCACATACACCTCCACACAGGAGAGACACCACACAAATGTCCCTTCTGTACTAAGACATTCTCAAGAAAGGAGCATCTTACCAACCATGTTAGAATCCACACGGGTGAGTCGCCGCACCGCTGCGAGTTCTGTCAGAAGACGTTCACGCGGAAGGAGCACCTCACGAACCACATGAAACAACACACGGGTGACACCGCGCACGCGTGCAAGATATGCTCCAAGCCTTTTACAAGGAAGGAACATCTTGTTACGCACATGAGATCGCACAGTTGTGGGGAGAGGCCTTATAGTTGTGGCGAATGCGGCAAGTCGTTCCCGTTGAAAGGCAATCTATTGTTCCACGAGCGGTCGCACAATAAGGGCACGAGGCCATACCGGTGCGACATCTGCTCCAAGAACTTCTTATGTAAAGGGCATTTAGTATCTCACCGGCGCACGCACACGGAGGCGGGCGAAAACCCTCCCAGCGGAGACGCGCCCGCTGAGTCCGAAGACTGCACCGACTGCAACAAGTGCGTCAAGGTTGAAGTCGAAGCGCCTGAAAGAAAGCACGAAATCAGAGCTGCAGTTGAAAATCGGCCAGCTGAAAACAATGTTACTCAACCTCAACAAAACAACGCAGCTGTTATGCAAATAAATAATCAGCAGGTCCGAGCAGTGACCGCGACGAGTTCGCAAGGCGTGACCCCCGGCACGTTCACACACACTGCCAGCACGCAGCACCACACGGGGACGGCCATAGCGCACCACCCCGTCACTGTCAACTACTAG
Protein Sequence
MNPEHHNINTGGGQPPGSTESQNQRVQSAQQKQQSNLTPTTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPTGTRIENGKPVQDLGQAHASILNGDPNILLGHHGAQPQVTVSASGAQQIPVSQIIATQSGQTHEALVGHSQAQEMGAGGGAGAAVGAPHASHSAHAPHATHATHAHHQVPNNRVEFVQHHNIDMGHHSQQHNMMQQQLMATSRQDHPNQQIQLTVSEDGIVTVVEPGGGKMVDKEELHEAIKIPSDHALTVHQLQQIVGQQVIDSVVRIEQATGEPANILVTHNADGTTSIEASAADHAPLVKDENKQPKIDAQFAIPAEIKDIKGIDLKTVGAMGMEGAVVKISAGASEHDMHAMYKVNVEDLSQLLAYHEVFGKLNSEGQPQQQAKVISEVEVEPGTSAAMSEPESSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPSERHTKRLTQDKPYACTACHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRKEHLVNHMRSHTNDTPFRCDLCGKSFTRKEHFNNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTYCSKSFTRKEHLTNHIRQHTGETPHKCTFCPRAFARKEHLNNHIRQHTGVTPHACSYCSKTFTRKEHLVNHIRQHTGETPFKCTYCSKSFSRKEHLTNHIHLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCEFCQKTFTRKEHLTNHMKQHTGDTAHACKICSKPFTRKEHLVTHMRSHSCGERPYSCGECGKSFPLKGNLLFHERSHNKGTRPYRCDICSKNFLCKGHLVSHRRTHTEAGENPPSGDAPAESEDCTDCNKCVKVEVEAPERKHEIRAAVENRPAENNVTQPQQNNAAVMQINNQQVRAVTATSSQGVTPGTFTHTASTQHHTGTAIAHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01030446;
90% Identity
iTF_00429225;
80% Identity
-