Spin020734.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Sphinx pinastri
Gene Symbol
Btbd3
Assembly
GCA_947568825.1
Location
OX387632.1:6291302-6301865[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.2e-26 3.9e-24 85.6 0.0 4 109 167 273 165 274 0.94
2 2 4.8 1.5e+03 -0.1 0.0 77 108 273 304 271 306 0.83

Sequence Information

Coding Sequence
ATGAAGGGAAGGCCTCTGAGAGCGCCTAGTAAATTGCCTGTGATATTGGGAAAAGTTCTACTGCGCTGGATCTTCACAAAAGCTGATCTGGTGTTCTTTGTTTATCGCTTTTTATGGTATGCTTGTCATATTCACGTCCGGTCCTCGATGAATAGCAGCGTGGATTTTTTCGAGAGTTTAATTGATGAAGACGGCCGCTTCGCCGAGTTAAATTGCCAAGAGCCGGCACAACGGGGACAAAGACAGCGTCCTCGACCACATATTCAAGCAGAAAACATTAATAATGGTGGCGGGTTGTCGCTGTCGCCCCCGCACACGGTTTCTCAGCGCGAGACAGGCACGCAGGTGTCTCAATGCTACAGCGGGCCGCCGTCACCATGCGGGTCTGCCAGCACTTCCCCGTCTCCCATGGTGTCGCCCGCTCCGCCACCAGGCACTGCCACATTGGATCCTAACTGGCAAGCAACTAAACCCACTGTCCGGGAACGGAACGCAGCCATGTTCAACAACCAGCTTATGTCAGACATTACATTCATAGTCGGAGGACCAGGACATACTAGAGTGATACCAGCTCACAAATATGTATTAGCTACTGCCAGTTCTGTTTTCTATGCTATGTTTTATGGAGGTTTGGCAGAATGCAAGCAAGAAATCGAGGTACCTGATGTGGAACCATCTGCCTTCCTGACCCTGTTAAAATATATCTATTGTGATGAAATACAATTGGAAGCGGACACAGTATTGTCAACTCTTTATGTTGCAAAAAAATACATTGTTCCGCATTTAGCCAAAGCTTGTGTCAATTATCTTGAAACTAGTCTGACGGCAAAGAATGCATGTCTACTTTTGAGCCAGTCAAGATTGTTTGAAGAGCCAGAACTGATGCAAAGATGTTGGGAAGTGATTGATGCTCAGGCAGAAATGGCACTGACTTCAGAAGGATTTGTGGACATTGATGTTTCAACACTTGAATCTGTATTAGCAAGAGAAACACTTAACTGTAAAGAGATCAATCTGTTTGAAGCTGCTCTAGCTTGGGCGCATTCTGAGTGTGTGCGGAGAGAGATTGACCCTACCCCAACAAACAAAAGAGCCATGCTTGGAAGTGCCATATATTTAATTAGATTCCCGACAATGTCTTTGGAAGAATTTGCAAATAGTGCCGCTCAACTTGGCATATTGACTCCCCAAGAAACTATTGACATATTTTTGCATTTCACTGCCTCAAGTAAACCACAATTATCCTATCCTATCAAACCCAGGGCTGGACTGAAGGCTCAGATTTGTCACAGATTCCAGTCCTGTGCGTATAGAAGCAACCAATGGAGATACCGTGGTAGATGTGATTCTATTCAGTTTTGTGTGGACAAAAGAATATTTGTTGTGGGATTTGGACTATATGGATCTTCAAATGGTGCAGCCGACTATAATGTTAAGATAGAATTGAAGCGTTTGGGCAGAGTGCTAGCAGAAAACAACACGAAATTTTTCTCAGATGGTTCCAGTAACACTTTCCATGTGTACTTCGAGAACCCCATACAAATTGAACCAGAATGTTTCTACACCGCATCTGCAATCCTTGATGGGAGCGAACTGAGCTATTTTGGACAAGAAGGATTGAGTGAAGTATATATGGGTACTGTAACATTCCAATTCCACTGTTCATCAGAAAGTACCAATGGCACTGGAGTGCAAGGAGGACAGATACCAGAACTCATCTACTATGGTCCTACGGTCAACACTTCAGCAATGACAAATGCAAACACAAATGAGGACTGA
Protein Sequence
MKGRPLRAPSKLPVILGKVLLRWIFTKADLVFFVYRFLWYACHIHVRSSMNSSVDFFESLIDEDGRFAELNCQEPAQRGQRQRPRPHIQAENINNGGGLSLSPPHTVSQRETGTQVSQCYSGPPSPCGSASTSPSPMVSPAPPPGTATLDPNWQATKPTVRERNAAMFNNQLMSDITFIVGGPGHTRVIPAHKYVLATASSVFYAMFYGGLAECKQEIEVPDVEPSAFLTLLKYIYCDEIQLEADTVLSTLYVAKKYIVPHLAKACVNYLETSLTAKNACLLLSQSRLFEEPELMQRCWEVIDAQAEMALTSEGFVDIDVSTLESVLARETLNCKEINLFEAALAWAHSECVRREIDPTPTNKRAMLGSAIYLIRFPTMSLEEFANSAAQLGILTPQETIDIFLHFTASSKPQLSYPIKPRAGLKAQICHRFQSCAYRSNQWRYRGRCDSIQFCVDKRIFVVGFGLYGSSNGAADYNVKIELKRLGRVLAENNTKFFSDGSSNTFHVYFENPIQIEPECFYTASAILDGSELSYFGQEGLSEVYMGTVTFQFHCSSESTNGTGVQGGQIPELIYYGPTVNTSAMTNANTNED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00720481; iTF_00859624; iTF_01173409; iTF_01220770; iTF_00034913; iTF_00146561; iTF_00736737; iTF_00319046; iTF_00012136; iTF_01018700; iTF_00448270; iTF_00651886; iTF_01492142; iTF_00794801; iTF_01332946; iTF_00035860; iTF_00072212; iTF_00382804; iTF_00432372; iTF_01425236; iTF_01426037; iTF_00013208; iTF_00450297; iTF_00075674; iTF_00383835; iTF_01302523; iTF_01017852; iTF_00017469; iTF_00889375; iTF_00008160; iTF_00072960; iTF_00820257; iTF_01331817; iTF_01334022; iTF_00648256; iTF_00710339; iTF_00710340; iTF_00357769; iTF_00358762; iTF_01193711; iTF_00115063; iTF_00711129; iTF_00771197; iTF_01166851; iTF_01180420; iTF_00707109; iTF_00819301; iTF_01071749; iTF_00408580; iTF_01503111; iTF_00783656; iTF_01148936; iTF_01280521; iTF_00752202; iTF_00961066; iTF_00785323; iTF_00784525; iTF_01504016; iTF_01124722; iTF_00074676; iTF_01282484; iTF_01282486; iTF_00076696; iTF_01285689; iTF_00365056; iTF_01125600; iTF_01172517; iTF_00207110; iTF_00206223; iTF_00689510; iTF_01033862; iTF_00959522; iTF_01034725; iTF_00421479; iTF_00709383; iTF_00931595; iTF_00420654; iTF_00958766; iTF_00842799; iTF_00419856; iTF_00932785; iTF_00419090; iTF_00157336; iTF_00441657; iTF_00960281; iTF_00461696; iTF_01342341; iTF_00687974; iTF_00403950; iTF_00934947; iTF_01248323; iTF_01178757; iTF_00288967; iTF_00744871; iTF_00925869; iTF_00406030; iTF_00933968; iTF_00786930; iTF_01217620; iTF_00164504; iTF_00261977; iTF_00114208; iTF_00281511; iTF_01502222; iTF_00284680; iTF_00143176; iTF_00159976; iTF_00787802; iTF_01073728; iTF_00283713; iTF_01353855; iTF_01312329; iTF_01317425; iTF_00323626; iTF_00824002; iTF_00823159; iTF_01197915; iTF_00236747; iTF_00235968; iTF_00290828; iTF_00869794; iTF_01430058; iTF_00341457; iTF_01010518; iTF_00858700; iTF_01416973; iTF_00428271; iTF_00640546; iTF_00429162; iTF_00026991; iTF_00027900; iTF_00834767; iTF_00837697; iTF_00835721; iTF_00836703; iTF_00700240; iTF_00702114; iTF_00856771; iTF_00696580; iTF_00250597; iTF_00267333; iTF_00698438; iTF_00705158; iTF_00737606; iTF_00119719; iTF_00355335; iTF_00706152; iTF_01099912; iTF_00279242; iTF_00377226; iTF_00663210; iTF_00661451; iTF_00703084; iTF_00704140; iTF_00638765; iTF_01529325; iTF_00204462; iTF_00701199; iTF_00662352; iTF_00686480; iTF_01219889; iTF_00697490; iTF_01528435; iTF_00033941; iTF_01336053; iTF_00811158; iTF_01429174; iTF_01161495; iTF_01509719; iTF_01183033; iTF_00406874; iTF_00632892; iTF_00699356; iTF_00909820; iTF_00318205; iTF_00407709; iTF_00361759; iTF_01501283; iTF_00321709; iTF_01337005; iTF_00275447; iTF_01170711; iTF_01403577; iTF_00844508; iTF_01171580; iTF_00791327; iTF_01179601; iTF_00001298; iTF_00673618; iTF_00887521; iTF_00971490; iTF_00970532; iTF_01082597; iTF_00942957; iTF_00288174; iTF_00167024; iTF_01438160; iTF_01387733; iTF_01388630; iTF_00795832; iTF_01081724; iTF_01439164; iTF_00828068; iTF_01205830; iTF_01204199; iTF_01205031; iTF_01206695; iTF_00878959; iTF_00430782; iTF_01202592; iTF_01360824; iTF_01020447; iTF_01316499; iTF_00158164; iTF_00467508; iTF_00468281; iTF_01546772; iTF_01544070; iTF_01545006; iTF_01543087; iTF_01547983; iTF_01545873; iTF_00276579; iTF_01341449; iTF_00433280; iTF_01561237; iTF_00761814; iTF_00822102; iTF_01564823; iTF_01562120; iTF_00006392; iTF_00897008; iTF_00187288; iTF_00715896; iTF_01490264; iTF_01436249; iTF_01083492; iTF_00025338; iTF_01377626; iTF_01437210; iTF_00642491; iTF_00458177; iTF_01151331; iTF_00954694; iTF_00953679; iTF_00802039; iTF_01092184; iTF_00353278; iTF_00205312; iTF_00282556; iTF_00833209; iTF_01281468; iTF_01279408; iTF_00724061; iTF_00908990; iTF_01076670; iTF_01487838; iTF_01221734; iTF_00185450; iTF_00186410; iTF_01487837; iTF_00327198;
90% Identity
iTF_01546772;
80% Identity
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