Basic Information

Gene Symbol
Aef1
Assembly
GCA_009176505.1
Location
VUAH01006149.1:777628-784148[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.00086 8.4 6.7 0.1 21 48 23 50 14 54 0.86
2 4 6.6e-05 0.64 10.3 0.1 21 47 51 77 49 82 0.86
3 4 0.0036 35 4.7 0.0 21 47 79 105 77 110 0.84
4 4 2e-05 0.19 12.0 0.1 21 52 107 138 102 140 0.89

Sequence Information

Coding Sequence
atgaaCTTGAAGTTTGAGTCGCATATGTCTAGAGCCCTAAGTCGTGCAATTACAATGACTGTCAGCGCTGAAAAGCCGTTCCAATGTGCTGTATGTGAAAAACAATTCCGTCAGCTAAGTACGCTCACAAACCACTACAAAATCCACACCGGAGAAAAGCCATTCAAATGTCATATATGCGATAAGCGATTCAGGCAATCGAGCACGTTGACGAACCATGCGAAAATTCATACAGGCGAGAAACCGTTCAGCTGCAATTACTGCGCAAAACTATTCCGACAACTAAGCACACTAATCAACCACACGAAGATACACACGGGAGAAAAGCCTTTCGAATGCGCCGTGTGCAAAAAACAATTTAGACAGTCTAGTACTCTAAACAATCATATTAAAATCCATGTATCGGATAAACCGTTCTTGCAAGAGCTGCAGGAAGCCCACAATAATCGATTTAAGCAGGAGCCACAACAAGACGCAACGATGTGA
Protein Sequence
MNLKFESHMSRALSRAITMTVSAEKPFQCAVCEKQFRQLSTLTNHYKIHTGEKPFKCHICDKRFRQSSTLTNHAKIHTGEKPFSCNYCAKLFRQLSTLINHTKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVSDKPFLQELQEAHNNRFKQEPQQDATM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01351110;
90% Identity
iTF_01351110;
80% Identity
iTF_01351110;