Basic Information

Insect: Sitobion miscanthi
Gene Symbol: ham
Assembly: GCA_008086715.1
Location: Lachesis:4406674-4447375[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.099 36 4.9 0.7 5 23 263 282 260 283 0.88

2 9 0.082 30 5.2 0.2 3 23 291 312 289 312 0.92

3 9 1.1e-09 4e-07 30.0 0.9 1 23 316 339 316 339 0.98

4 9 1e-06 0.00037 20.6 2.5 1 23 345 367 345 367 0.95

5 9 5.8e-06 0.0021 18.3 5.0 1 23 373 395 373 395 0.99

6 9 0.00055 0.2 12.0 0.9 2 21 403 422 402 423 0.95

7 9 7.9e-10 2.9e-07 30.4 0.5 1 23 844 866 844 866 0.98

8 9 4.9e-07 0.00018 21.6 1.9 1 23 872 895 872 895 0.97

9 9 6.7e-07 0.00024 21.2 3.4 1 23 901 923 901 923 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.099	36	4.9	0.7	5	23	263	282	260	283	0.88
2	9	0.082	30	5.2	0.2	3	23	291	312	289	312	0.92
3	9	1.1e-09	4e-07	30.0	0.9	1	23	316	339	316	339	0.98
4	9	1e-06	0.00037	20.6	2.5	1	23	345	367	345	367	0.95
5	9	5.8e-06	0.0021	18.3	5.0	1	23	373	395	373	395	0.99
6	9	0.00055	0.2	12.0	0.9	2	21	403	422	402	423	0.95
7	9	7.9e-10	2.9e-07	30.4	0.5	1	23	844	866	844	866	0.98
8	9	4.9e-07	0.00018	21.6	1.9	1	23	872	895	872	895	0.97
9	9	6.7e-07	0.00024	21.2	3.4	1	23	901	923	901	923	0.99

Sequence Information

Coding Sequence: ATGAGCAGAGGCAGTAGCGACGATGGAGGTGGCGGCAGTGGCGACACGGACGCCGGCCGGAGCGACGACGAGCGTTCGTTGTCAAGTGACAGTAGCGGCGGTGGCGGCGGCGGCGGCGTCGTCGTCGTCGTCGGAGACGGTTGCCGGAGCCGGAGCAGCAGCGCAAACAGCAACAACAACAACGGGAAAAAAGACACGATTGCGGCTGTCGACGAGGTCGGTGGCGTCATCGGCGCGGGTTTGAACAACAGTTTCAACTTTTTCGAGCTGCCGGCCAACGCGGCCACCATGCCGTACAACTTGGAGTTGCGGAACGCTGGTGCGAGCGGCGTCTGGACAAAGACACAGCTCCCCAAAGGTGTCAAGTACGGTCCGTTCCTGGGCAAATGGGGCCCGAAGCCGGTGGACTCGCGGTTCGCCTGGGAGGTTCGCATCGCCGGGTACTCTGGATATTTGGACGGGACGATTGAAATCTGTAATTGGCTGAAATTCATCAGATCCACGAACGACTGTAGTAGACAAAACGTACGGGCGTTCTTGTTGGCCGGACAGATATTTTACGAATTGACACAAACGGTCAAAGCTTCAGAAGAACTACTGTTGGGCAAGAGAGAGCCGCTTAATTTAGACGCAGCATTTGGAGAATTAATGACCACGTCTGCAGAGGATCGGAGTGAAAGAGATTCGGTCGTCGCGTCGCAGAACTCACTGGGATCGATCGACGGCGACGGAGACGTGGACGTGGACGCCGAGGAGCCGGACGAGGACGACCAAAATCGGTGCATCTTGTGCGAGAAGTGTTTTCCCGACATCGAACAGCTCGATGATCACCTGGTGTCCGGTCACCACTACAAGGCGAGTCAGTACGGGTGTGAGCTGTGCCCGCAGTCTTACAGCTGGAAACCGTGCCTGATCCGGCACCTGGCTTTGGCCCACAGCCGAAAGTTCACGTGCGAGACCTGTTCCAAGGTGTTCAGCGACCCGAGCAACCTGCAGAGGCACATCCGGACCAATCACGCGGGTGCCCGGTCGCACGCCTGTTCCGAGTGCGGCAAAACGTTCGCCACGTCCAGCGGCCTCAAGCAGCACACGCACATACACTCCAGCGTGAAGCCGTTCCAGTGCGAAGTCTGTTTCAAGGCGTACACTCAGTTCTCGAACCTCTGCCGGCACAAGAGGATGCACGCCGACTGCCGCATGCAAGTAAAGTGTGACCGGTGCGACCAGTCGTTCAGCACGGGCACGTCGCTGTCCAAACACAAGCGGTTCTGCGAGTCGAACCCGTCGCCGTCGCCGTCGTCGCTCGCGGCGTCCGGCGTGCCCGCCGGTGGCGGAATGTCGTCGTTACAGCAACAGCCCGGGGCCGCGGCCACCGCCGGGTCTTCGCCGTTCGCCGTCTACCCGCGGTTCCCGCTGTACCCGCCGCACCCGCTCGTCCACCCGTTCTACTTCCCGCTGGCGAACGGATCGCTGCCACCGCCGCTGTTCCCGTCGCCGTTCGGTCAGTTTGCGCCCAATCTGAACATGGACATGCTGTCGCTGTCCAACGCCGTCGAGATGTGCAACAACCGGTTCAAGAGGTCTGCAGGCGAATCGGAACATAACGAGACGCCCGCCAAGCGGTCGTCGTCGTCGTCGTCGTTCAACGCCGGCCAGAAGACTCCGCCGCCTCAGCTGCCGACATCGTCCGGCGTGGCCATGCTGATGGGCTCGAGCAAGACGTCGCCGCTGGTCGGCGAAGAGGCGTCATCCAACCAGCGGCCATCGCCGGCCCGCCCCAGCGCCACGTACCCCGACCCCAAGGTGCACGTCAAGCGGCAGCCGTCCGGGGACGAGGATTGCGGCCCGTGTGACCTGTCCGTAAACACTGACATTCTGTGCAACGGCGGCGGTTCGGCGGACGAGTTGACAACCGACGACAGTGCTGGCGGACGCCGGTCGTCGGACGATGACGGATCGCCGTGCCGATCGGCGGACCAGCCGCTGGACCTGTCGGTAACGAAAATTCAGCGCCGGCGAAAAAAGTCGCCGACGGCCGTCCGCGCAACACCGCGGGACGACAGCCCGCGCGCCGAGAATACCGGCGGGCGACCGGAGCAGCGCGGCCGCAAGTGGTCGCCGCCGTCTTCGACACCGCCCCCACCACCACCCCCGCCACCACCGCCGCCGCCGCCCCAGAGACCGTCGTCGTCGTCGCCGTACTCGGTCAGCAACCTGATGGCCTACCCCAAACCGCTGTACTTGGACTCGATGTATCCGGCCACGCTGTCCGGGTTCGCAGAGAGCCAGCTGCAGCACATGCAGGGACATCAGCCTTTCGGGCCGTCCGCCTCCAGGACGTTTCCGTTCATGTCCAACTCGTCGCCGGCCATCGAACACTTTCTCAGGCAGCCCATGCCCAACTACTCGAAATCGTACCAAGACATCATCCAGCAGCACCAGAACCATCACGGACAGCACCAGAACCAGCACGGACAGCAGCAGCAGCTCCAACAGCAGCAGCAGCAGCACGTCAAGTCCAAGGACAGGTACGCGTGCAAGTACTGCGGCAAGGTGTTCCCGCGCAGCGCCAACCTGACCAGGCACGTGCGAACGCACACCGGCGAACAGCCGTACCGGTGCGCGCACTGCGAACGGTCGTTCAGCATATCGTCCAACCTGCAGCGGCACGTGCGCAACATCCACCGGCAGGAGCGCAATTTCAAGTGCAATCTGTGCAACCGGCGGTTCTCGCAGCAAACCAATCTGGACCGGCACGTCAAGAAGCACGAGGCGGACGACGGTACCGCCGTCGGCACCGTCACCAGCAGTTCGGCGAGCAGCGTGGACGAGAAGGAGGACCCCAGGCTGTTCGAGATCCGGAGCTTCATGAAGAAGGTGAGCGACCACGGGTCCGCGGCCGCGGCCGCGGCCGCCGCCGCCGAGATGCAGAACAACAACGTGGTGGTGGACCCGTGCGGTCTGCAACAGCCCGACGACGGTCTGCAGTACGCGGCCCACTTATGA
Protein Sequence: MSRGSSDDGGGGSGDTDAGRSDDERSLSSDSSGGGGGGGVVVVVGDGCRSRSSSANSNNNNGKKDTIAAVDEVGGVIGAGLNNSFNFFELPANAATMPYNLELRNAGASGVWTKTQLPKGVKYGPFLGKWGPKPVDSRFAWEVRIAGYSGYLDGTIEICNWLKFIRSTNDCSRQNVRAFLLAGQIFYELTQTVKASEELLLGKREPLNLDAAFGELMTTSAEDRSERDSVVASQNSLGSIDGDGDVDVDAEEPDEDDQNRCILCEKCFPDIEQLDDHLVSGHHYKASQYGCELCPQSYSWKPCLIRHLALAHSRKFTCETCSKVFSDPSNLQRHIRTNHAGARSHACSECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQVKCDRCDQSFSTGTSLSKHKRFCESNPSPSPSSLAASGVPAGGGMSSLQQQPGAAATAGSSPFAVYPRFPLYPPHPLVHPFYFPLANGSLPPPLFPSPFGQFAPNLNMDMLSLSNAVEMCNNRFKRSAGESEHNETPAKRSSSSSSFNAGQKTPPPQLPTSSGVAMLMGSSKTSPLVGEEASSNQRPSPARPSATYPDPKVHVKRQPSGDEDCGPCDLSVNTDILCNGGGSADELTTDDSAGGRRSSDDDGSPCRSADQPLDLSVTKIQRRRKKSPTAVRATPRDDSPRAENTGGRPEQRGRKWSPPSSTPPPPPPPPPPPPPPQRPSSSSPYSVSNLMAYPKPLYLDSMYPATLSGFAESQLQHMQGHQPFGPSASRTFPFMSNSSPAIEHFLRQPMPNYSKSYQDIIQQHQNHHGQHQNQHGQQQQLQQQQQQHVKSKDRYACKYCGKVFPRSANLTRHVRTHTGEQPYRCAHCERSFSISSNLQRHVRNIHRQERNFKCNLCNRRFSQQTNLDRHVKKHEADDGTAVGTVTSSSASSVDEKEDPRLFEIRSFMKKVSDHGSAAAAAAAAAEMQNNNVVVDPCGLQQPDDGLQYAAHL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01033227;
90% Identity: iTF_00942107;
80% Identity: -