Meup032493.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrosiphum euphorbiae
Gene Symbol
mecom-b
Assembly
GCA_949089665.1
Location
CARXXK010000003.1:48155948-48172830[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 1.1 1.5e+02 5.1 0.7 5 23 179 198 176 199 0.88
2 9 0.92 1.2e+02 5.3 0.2 3 23 207 228 205 228 0.92
3 9 1.2e-08 1.6e-06 30.1 0.9 1 23 232 255 232 255 0.98
4 9 1.1e-05 0.0015 20.8 2.5 1 23 261 283 261 283 0.95
5 9 6.5e-05 0.0085 18.4 5.0 1 23 289 311 289 311 0.99
6 9 0.0062 0.81 12.1 0.9 2 21 319 338 318 339 0.95
7 9 8.9e-09 1.2e-06 30.5 0.5 1 23 764 786 764 786 0.98
8 9 5.5e-06 0.00072 21.8 1.9 1 23 792 815 792 815 0.97
9 9 7.5e-06 0.00098 21.3 3.4 1 23 821 843 821 843 0.99

Sequence Information

Coding Sequence
ATGAATTACATATTACAGTTACTACGTCGACTATCCGTATTGGATTGTTGTATCAACCATCAATTAACACCCGCAAAGGGTTCATCTTTTTCTTGGGTGAAGGGTGCACTGCGAAACGTCGCTAGTGGTTTCTCCTTTATATACGATTCTTTTCAGACCCCGGACCCGCTGATGGTTCGCATCGCTGGGTACTCTGGATATTTGGACGGGACGATTGAAATCTGTAATTGGCTAAAATTCATTAGATCCACGAACGACTGTAGTAGACAAAACGTCCGAGCGTTCTTGTTGGCCGGACAGatattttacgAATTGACACAAACAGTCAAAGCTTCAGAAGAACTATTGTTGGGCAAGAGAGAGCCGCTTAATTTAGACGCGGCATTTGGAGAATTAATGACCACGTCTGCAGAGGATCGGAGTGAAAGAGATTCGGtcGTCGCGTCACAGAACTCACTGGGATCGATCGACGGCGACGGAGACGTGGACGTGGACGCCGAGGAGCCGGACGAAGACGACCAAAATCGGTGCATCTTGTGCGAGAAGTGTTTTCCCGACATCGAACAGCTCGATGATCACCTGGTGTCTGGACACCACTACAAGGCCAGTCAGTACGGGTGTGAGCTGTGCCCACAGTCTTACAGCTGGAAGCCGTGCCTGATCCGGCACCTAGCTTTGGCCCACAGCCGAAAGTTCACGTGCGAGACCTGTTCCAAGGTGTTCAGCGACCCGAGCAACCTGCAGAGGCACATCCGGACCAATCACGCGGGTGCCCGGTCTCACGCCTGTTCCGAGTGCGGCAAAACGTTCGCCACGTCCAGCGGGCTCAAGCAGCACACGCACATACACTCCAGCGTCAAGCCGTTCCAGTGCGAAGTCTGTTTCAAGGCGTACACTCAGTTCTCAAACCTCTGCCGGCATAAGAGGATGCACGCCGACTGCCGCATGCAAGTAAAGTGTGACCGGTGTGACCAGTCGTTCAGCACGGGCACGTCGCTGTCCAAACACAAGCGGTTCTGCGAGTCGAACCCGTCGCCGTCGCCATCGTCGCTCGCGACGTCTGGCATGGCTACCGGTGGCGGAGTGTCATCGTTACAGCAACAACCCGGGGCCGCGGCCACCGCCGGGTCTTCGCCGTTCGCCGTCTACCCGCGGTTCCCGCTGTACCCGCCGCACCCGCTCGTCCACCCGTTCTACTTCCCGCTGGCAAACGGATCCCTGCCACCGCCGCTGTTCCCATCGCCGTTCGGTCAGTTTGCGCCCAAGCTGAACATGGACATGCTGTCGCTGTCCAGTGCCGTTGAGATGTGCAACAACCGTTTCAAGAGGTCTGCAGGCGAATCCGAACACAACGAAACGCCCGCTAAGcggtcatcgtcgtcgtcgtcgttcaACGCCGGCCAGAAGACTCCGCCGCCGCAGCCGCCGACATCGTCCGGCGTGGCTATGCTGATGGGTTCGAGCAAGACGTCGCCGCTAGTCGGCGAAGAGGCGTCATCCAACCAGCGACCATCGCCGGCCCGCCCCAGCGCCACGTACCCTGACCCCAAGGTGCACGTCAAGCGGCAGCCGTCCGGGGACGAGGACTGCGGACCGTGTGACCTGTCCGTTAACACTGACATTCTGTGCAACGGTGGTGGTTCAGCGGACGAGTTGACAACGGACGACAGTGCTGGCGGACGTCGGTCGTCAGACGATGATGGTTCGCCGTGCCGATCAGCGGACCAGCCGCTGGACCTGTCGGTAACGAAAGTGCAGCGCCGGCGAAAAAAGTCTCCGACGGCCGTCCGCGCACGACCGCTGGACGACATCTCGCGCGCCGAAAATGCCGCTGTGCGACCAGAGCAGCGCGGCCCTAAGTGGTCGTCGCCGTCTTTGACACCGCCTCCAcccccaccaccaccaccgccgccgcctcaGAGACCGTCGTCATCGTCGCCGTACTCGGTCAGCAACCTGATGGCCTACCCCAAACCGCTGTACTTGGACTCGATGTATCCAGCTACGTTGTCCGGGTTCGCAGAGAGCCAACTGCAGCACATGCAGGGGCATCAGCCTTTCGGGCCGTCTGCCACCAGGGCGTTTCCGTTCATGTCCAACTCGTCTCCGGCCATCGAACACTTTCTCCGGCAGCCGATGCCCAACTACTCGAAATCGTACCAAGACATCATCCAGCAGCATCAGAACCATCACGGACAGCACCAGAACCAGCACGGACAGCATCAGAACCAGCaccaacagcagcagcagcaccaacagcagcagcagcacgTCAAGTCCAAGGACAGGTACGCTTGTAAGTACTGCGGCAAGGTGTTCCCGCGTAGCGCCAACCTGACCAGGCACGTGCGAACGCACACGGGCGAACAGCCGTACCGGTGCGCGCACTGCGAACGGTCGTTCAGCATATCGTCCAACCTACAGCGGCACGTGCGCAACATCCACCGGCAGGAGCGCAATTTCAAGTGCAATCTGTGCAACCGGCGGTTCTCGCAGCAAACCAATCTGGACCGGCACGTCAAGAAGCACGAGGCGGATGACGGTACGGCCGTCGGCACCGTTACCAGCAGTTCGGCGAGCAGCGTGGACGAGAAGGAGGACCCCAGGCTGTTCGAGATCCGGAGCTTCATGAAGAAGGTGAGTGATCACGGGTCTGCGGCCGCAGCCGCCGCCGCTGCCGCTGCCGAGATGCAGAACAACAACATGGTGGTGGACCCTTGCGGTCTGCAACAACCCGACGACGGTCTTCAGTACGCGGCCCACTTATGA
Protein Sequence
MNYILQLLRRLSVLDCCINHQLTPAKGSSFSWVKGALRNVASGFSFIYDSFQTPDPLMVRIAGYSGYLDGTIEICNWLKFIRSTNDCSRQNVRAFLLAGQIFYELTQTVKASEELLLGKREPLNLDAAFGELMTTSAEDRSERDSVVASQNSLGSIDGDGDVDVDAEEPDEDDQNRCILCEKCFPDIEQLDDHLVSGHHYKASQYGCELCPQSYSWKPCLIRHLALAHSRKFTCETCSKVFSDPSNLQRHIRTNHAGARSHACSECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQVKCDRCDQSFSTGTSLSKHKRFCESNPSPSPSSLATSGMATGGGVSSLQQQPGAAATAGSSPFAVYPRFPLYPPHPLVHPFYFPLANGSLPPPLFPSPFGQFAPKLNMDMLSLSSAVEMCNNRFKRSAGESEHNETPAKRSSSSSSFNAGQKTPPPQPPTSSGVAMLMGSSKTSPLVGEEASSNQRPSPARPSATYPDPKVHVKRQPSGDEDCGPCDLSVNTDILCNGGGSADELTTDDSAGGRRSSDDDGSPCRSADQPLDLSVTKVQRRRKKSPTAVRARPLDDISRAENAAVRPEQRGPKWSSPSLTPPPPPPPPPPPPQRPSSSSPYSVSNLMAYPKPLYLDSMYPATLSGFAESQLQHMQGHQPFGPSATRAFPFMSNSSPAIEHFLRQPMPNYSKSYQDIIQQHQNHHGQHQNQHGQHQNQHQQQQQHQQQQQHVKSKDRYACKYCGKVFPRSANLTRHVRTHTGEQPYRCAHCERSFSISSNLQRHVRNIHRQERNFKCNLCNRRFSQQTNLDRHVKKHEADDGTAVGTVTSSSASSVDEKEDPRLFEIRSFMKKVSDHGSAAAAAAAAAAEMQNNNMVVDPCGLQQPDDGLQYAAHL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01033227;
90% Identity
iTF_01350310; iTF_00019626; iTF_01033227; iTF_01167915; iTF_00463537;
80% Identity
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