Basic Information

Gene Symbol
zfh1_10
Assembly
GCA_958496175.1
Location
OY292279.1:43045475-43046597[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 3.3 7.5e+03 -2.7 0.0 34 40 52 58 50 67 0.70
2 3 1.3e-09 3.1e-06 27.4 0.1 21 51 221 251 213 255 0.86
3 3 0.44 1e+03 0.1 0.1 23 48 252 277 249 279 0.82

Sequence Information

Coding Sequence
ATGTCGAGAAAAGATCGTCAGATGGACGAATGTTTGATTTGTTCCGAGGAATACAAAATAATGATTCCATTGCAACAATGTCTAAGCGAATTTGCACACTTATCTGTCGCCCAAGTGTTGCAGCACATGaactttttaaatATTTCAGATGCTATAAACCAGACTCGAAATTTATGCCTTATGTGTGTggcaaaaattcaatattgttacgaatttaaaataaaatgtggtCACGTTGAAAGAGTATTGAAAAGTACAACCGACAATTTACGGGATGAGGCTGTTGTATCTCCATTGTGTAAAATCAAATCCGAAGACTTTGACGTAAACATTAAAGATGAACCTTACCAAGAAACAATCAACGAAAATTATCATTGCCAACAATTAAAAGTAGAAGAAACTCCAGAGGATTTGTATTCGGCAGATTCGATGGAATCTGCACAAAAACCATCGACTAGCGATTATTTTGTTTCCAATTCTGAGATTGAATTTCACGGCAAAATGTTTACCACCCAAGAAAGTTCTAATCTCCAATCCCGCAAAAGCAAGAACATGTGTCACAAAGTCAGAAAGAAAGAGGAAAAGAATGTAATGTGTTTGGTTtgtgagaaaaaattttatcgaaagCATCATTTAATTGACCATTCGAGAGTACATACGGGCGAAAAACCGTACACTTGCGATATTTgttataaatcattttccCAGTCGTGTAACTTAAAAAAGCACATGAAAGTAAAGCACAGTGACAAAAAGCCTCACGTGTGTGACGTGTGTAATAAATCATTTAGTTATCGTTGCTACTTAACTCGTCATATGTTAATTTATCACAATAAAGAGAAACATAAAAGGTGA
Protein Sequence
MSRKDRQMDECLICSEEYKIMIPLQQCLSEFAHLSVAQVLQHMNFLNISDAINQTRNLCLMCVAKIQYCYEFKIKCGHVERVLKSTTDNLRDEAVVSPLCKIKSEDFDVNIKDEPYQETINENYHCQQLKVEETPEDLYSADSMESAQKPSTSDYFVSNSEIEFHGKMFTTQESSNLQSRKSKNMCHKVRKKEEKNVMCLVCEKKFYRKHHLIDHSRVHTGEKPYTCDICYKSFSQSCNLKKHMKVKHSDKKPHVCDVCNKSFSYRCYLTRHMLIYHNKEKHKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01350058;
90% Identity
iTF_01350058;
80% Identity
iTF_01350058;