Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.3 5.2e+03 -2.1 0.5 26 43 55 72 53 76 0.84

2 7 0.00095 2.2 8.7 0.2 21 45 157 181 146 184 0.82

3 7 0.00029 0.66 10.3 0.1 21 51 185 215 181 218 0.84

4 7 0.087 2e+02 2.4 0.0 21 49 213 240 210 246 0.84

5 7 0.3 6.8e+02 0.7 0.0 15 31 235 251 224 267 0.81

6 7 0.099 2.3e+02 2.2 0.0 20 43 268 291 259 296 0.83

7 7 7.8e-05 0.18 12.1 0.0 21 44 297 320 294 324 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.3	5.2e+03	-2.1	0.5	26	43	55	72	53	76	0.84
2	7	0.00095	2.2	8.7	0.2	21	45	157	181	146	184	0.82
3	7	0.00029	0.66	10.3	0.1	21	51	185	215	181	218	0.84
4	7	0.087	2e+02	2.4	0.0	21	49	213	240	210	246	0.84
5	7	0.3	6.8e+02	0.7	0.0	15	31	235	251	224	267	0.81
6	7	0.099	2.3e+02	2.2	0.0	20	43	268	291	259	296	0.83
7	7	7.8e-05	0.18	12.1	0.0	21	44	297	320	294	324	0.89

Coding Sequence: atgacaaatttaAACCAAACTAACAAATGTTGGATTTGCAATGAACAATTTAAAGTTTCGTTGCACCAAAATCGAAGCGAATATGAGAAATTGCCAATGGCCCAAATTTCAGAAAACGCATCTTTTCCCACTaTTTCAGATGTTGCAATACTCTATCAAAACGTATGCTTTCTATGCACCGCCAAAGTTCAGTCTTGTCACGAATTGCAAAGGAAATGCAACCAATTAACAAAACAATTCGAAACTGCAACAAATCAATCACTTTCCGCTGCACATTTACTTCCATTTCTACCTGCGCCTACCACTAACTTACCAGAAGCAAATGACAAATATTTACATAGAAAATTCCGTAAGAAATCGAACCCAGATATTTCCACTTCCCCAATAATTGATCATTCCATTATAAAATCAATGGCCGACACCAATGAGGAAATTcttggcaaaaaaaaaaACAATACGGAAATCTCACCACAAAAGCCATTCATATGTCCAATTTGCCATAAAAGTTTTCTGTTCAACAGATATTTGCGTACACATTATCGAATCCATACCGGTGAACGGCCGCATGTGTGTGATGTTTGTCATAAAGCATTTACTCAATCTGGCGATTTGAATCGACATAGTGTAATTCATACGGGCGAAAAACCATTTGTTTGTGACGTTTGTAgtaaattatttaaacgaatCGATGCTTTGCTTAAACACAAGTTGCGACACAATGGGGAAAAACCATTCGTTTGTGATATGTGtagtaAACCTTTTATTACAGTCGGTGAACTAAAAAAACATAAGTTTACTCATTCTAATGAAAAACCATATGTTTGTGATCTTTGTAataAAACATTTGTTCGATCTGGTGATTTAAAGTCACATAAATTGATTCACAGTGGTGAAAAACCGCACGTGTGCGATGTGTGTAataAGTCATTTCGTCAAGGCAGTGGATTACGACGTCATAAATTATTGCatgccaaataa
Protein Sequence: MTNLNQTNKCWICNEQFKVSLHQNRSEYEKLPMAQISENASFPTISDVAILYQNVCFLCTAKVQSCHELQRKCNQLTKQFETATNQSLSAAHLLPFLPAPTTNLPEANDKYLHRKFRKKSNPDISTSPIIDHSIIKSMADTNEEILGKKKNNTEISPQKPFICPICHKSFLFNRYLRTHYRIHTGERPHVCDVCHKAFTQSGDLNRHSVIHTGEKPFVCDVCSKLFKRIDALLKHKLRHNGEKPFVCDMCSKPFITVGELKKHKFTHSNEKPYVCDLCNKTFVRSGDLKSHKLIHSGEKPHVCDVCNKSFRQGSGLRRHKLLHAK

Sequence clustering based on sequence similarity using MMseqs2