Basic Information

Insect: Siphlonurus alternatus
Gene Symbol: Hr39
Assembly: GCA_949825025.1
Location: OX463787.1:2147848-2162118[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.2 1.1e+04 -4.0 8.6 73 160 63 149 17 181 0.48

2 3 8.7e-09 8.1e-05 22.8 0.4 1 28 296 323 296 452 0.54

3 3 1.1e-66 1e-62 213.5 0.1 198 408 444 648 424 648 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.2	1.1e+04	-4.0	8.6	73	160	63	149	17	181	0.48
2	3	8.7e-09	8.1e-05	22.8	0.4	1	28	296	323	296	452	0.54
3	3	1.1e-66	1e-62	213.5	0.1	198	408	444	648	424	648	0.93

Sequence Information

Coding Sequence: ATGGAGGGAGTGCAATGTGGGGGAGCGTCCCCACCCCGATGTTCTCCACCCCCGGTACCCCAGGACGTGAAACCACCTCATCAGCTGGAGAAAGGACTTCACGTATCAACCCCAGAACACATCAACGAGACGGTCCTAAAGGGGGTAATTCTACCCCCCGGACCTCCCTACACCCCCAGTCAGAGCCCCCTGACTCAACGTCATCTGCTACATAAACATCATCCACCAACCCCAAGTCCAGACTCTGCAATTCATTCTGCGTACTACAGTCCTACGCAGTCTCCAGTGGCTTCCAGACATCCGCTGAGTTCATCAGGATTTAGTAGTCCGTATTCTACGAGGCATGCTACACCTTCATTATCAAGAACGAGCTCTGATGCGTCACAGTACTCCCAACACTCCACGGGCTCCTGCTACAGCTCTCCAGCCCAGTTCTCCTCGCCGTGCCACTCTCCGGTCCAGACTCGACACCCGCTACATTTGCTGGCACACTCTTCTCTGTCGAGAGAATTCTCAGTGCCACAGCCACCCAGCGCAGGCGTAGTGGTGTACGCCAGGTCCGAGGAGGAGAAACTTATCTACCTGCATGAGCAGGGGCAGCAAGATgAAGAAGGAGAGGATCCCCCAAGTCTATCTTCAGGTCCAGGAATCTCCAGACAACAGCTGATCAACTCTCCATGTCCAATCTGCGGTGATAAGATCTCTGGATTCCACTATGGTATCTTCTCGTGCGAGAGCTGCAAGGGTTTCTTCAAACGTACAGTACAGAACCGGAAAAACTACGTCTGTCTACGTGGATCTGCGTGTCCTGTATCCATTGCTACTCGTAAGAAATGTCCAGCGTGCAGATTCGACAAGTGTCTAAAGGCAGGCATGAAGTTAGAGGCTATCCGCGAGGACCGTACTAGAGGTGGTCGCAGTACGTACCAATGTTCGTACACTCTGCCCTCCACACTGCTGCCTCCTGGTGGTGGAACTGAGCAACACGGCTCTCCTGGCAAGATGGGACCTCTGTCATCAGGATTGGGGGCATCAACCTCTTCTCAGGTGTCTCCACTTCCTGCCTCCGCTGAGCTTCGCGTCAAGACGGAATCTGGTTCCGACCTTGGAGGCTCAAGCTCCGGTAGCCACGGTAACGGACTTGTATGTGCCGTGCCACAGCTGCTTCAGGAGATAATGGATGTGGAGCACTTGTGGCACTACGAACAGAGTGGTGGAGGTCGCAGCAGGCGCGGAGAAAGTTCATCAAGTTCTGCTACGTCTGCATCGCGGGCGGAGGAGGCCATGGCCAGCGCTTCGTCCTCCAGTCAGGACTTCCTGCAGGCTGCCGCAGCGTCCAGTGGTGGAAGTCCAGACTTCATTCAGAACCTCTGCTCCATCGCGGACCATCGACTTTACAAGATCGTCAAGTGGTGCAAGAGTCTGCCCCTCTTCAAGAATATCTCCATTGATGACCAGATATCCCTGTTGATCAACTCGTGGTGCGAACTCCTCCTCTTCTCGTGTTGTTTCCGCTCCATGTCCTCTCCTGGAGAGATCAGGGTCTCTCTGGGAAAGTCCCTGTCTCTAGAGAGGGCCCGGGCCCTGGGACTGGGACCCTGCATAGAGAGGATGCTAAACTTCACAGAGCATCTTCGTAGATTGAGGCTGGACAAGTACGAGTATGTTGCAATGAAGGTCATCGTGCTGCTCACATCAGATACTTCTGACCTGAGAGAGCCTGAGAAGGTTCGAGCCTCGCAAGAAAAAGTTCTCGAAGCTTTACAACATTACACTCTCCAACGATATCCGGATCTTCCATCGAAGTTCGGGGAGCTTTTACTGAGGATCCCGGAGCTTCAGCGAGCCTGCCAGGTTGGGAAGGAGATGTTGAGCCTTAAGAACAAAGATGGGGAGGGTCCTGCGAGCTTCAACTTGCTGATGGAGTTACTAAGAGGGGACCATTGA
Protein Sequence: MEGVQCGGASPPRCSPPPVPQDVKPPHQLEKGLHVSTPEHINETVLKGVILPPGPPYTPSQSPLTQRHLLHKHHPPTPSPDSAIHSAYYSPTQSPVASRHPLSSSGFSSPYSTRHATPSLSRTSSDASQYSQHSTGSCYSSPAQFSSPCHSPVQTRHPLHLLAHSSLSREFSVPQPPSAGVVVYARSEEEKLIYLHEQGQQDEEGEDPPSLSSGPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSACPVSIATRKKCPACRFDKCLKAGMKLEAIREDRTRGGRSTYQCSYTLPSTLLPPGGGTEQHGSPGKMGPLSSGLGASTSSQVSPLPASAELRVKTESGSDLGGSSSGSHGNGLVCAVPQLLQEIMDVEHLWHYEQSGGGRSRRGESSSSSATSASRAEEAMASASSSSQDFLQAAAASSGGSPDFIQNLCSIADHRLYKIVKWCKSLPLFKNISIDDQISLLINSWCELLLFSCCFRSMSSPGEIRVSLGKSLSLERARALGLGPCIERMLNFTEHLRRLRLDKYEYVAMKVIVLLTSDTSDLREPEKVRASQEKVLEALQHYTLQRYPDLPSKFGELLLRIPELQRACQVGKEMLSLKNKDGEGPASFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00630639;
90% Identity: iTF_01348101;
80% Identity: iTF_01348101;