Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.014 6.2e+02 2.9 0.1 26 43 158 176 147 182 0.70

2 5 0.0036 1.6e+02 4.7 0.0 22 45 184 207 178 214 0.85

3 5 0.002 92 5.5 0.1 22 46 212 236 207 239 0.89

4 5 3.2e-05 1.5 11.3 0.1 21 51 239 269 235 270 0.88

5 5 0.00074 34 6.9 0.0 21 48 267 294 265 297 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.014	6.2e+02	2.9	0.1	26	43	158	176	147	182	0.70
2	5	0.0036	1.6e+02	4.7	0.0	22	45	184	207	178	214	0.85
3	5	0.002	92	5.5	0.1	22	46	212	236	207	239	0.89
4	5	3.2e-05	1.5	11.3	0.1	21	51	239	269	235	270	0.88
5	5	0.00074	34	6.9	0.0	21	48	267	294	265	297	0.90

Coding Sequence: ATGGAGAATGAGGAGCAGGAGGTCGAGTTTCATTCCACGCTGGAGCCCGATATTATTATCGACGACAGCTCGCGGCGCGCGGGGCGCGATTTCGGCCCGTTCGAACCGATTTCGGCGCTCCAGCCGCGATCCTGGGCGTCTCATGCAAAGTGGCGTGCATTTTTGTGGAATTGCATCTGGGATGACGAATTTTATgaaaaccaacaagaaaatGCACGCGCCGAACTCACAAACAACCTTCAGAAGCGCATTGGGCCAGAGGTGTCTCTCATCCCTGTCAAAAAGAGCACCATCAGAGTCAAGATGTTTAGCAAAATGGTCGAACGGGAGCCGCCACCGGAACCAGAGGAACACAAAGTACAAAGGATAATTCATAGATCTCCCAGGCAAACTGTAAGACTGATATCTAAAGAAGAAATGATCCAGGCTGAGACCGGCTGCAACTCGAAACGCAAATCGCTTCCACTAGAGAAATGCCctatttgtaaaaagtttttccGCCGCATGAAGACCCATCTACAGAAACATGAAAACGTAAAGCGAGACCCCAACGACCCCCTTACTTGTCGGTACTGCATGAAGGTCTTCAACACGGGCAGCAATCTGAGCATACACATGCGCACGCACACTGGAGACAAGCCGTACATTTGTGAAGTGTGCACGAAAGGTTTTGCGCAGTCTTGCAATCTCGTAAATCACATGCGCATCCATACCGGTGAGAGACCATTCAAGTGCCCCCACTGTGACCGTGCTTTTACACAGTCTGGCAATCTTAGCAATCATGTGCGCCTGCACACTGATGAAAAACCCTTCAAATGCCATTTTTGCGACAAAGCCTTCACGCAGTCTGGCAATCTCAACTCCCACATTAGAAACAATCACAAATTTGTTGATAACATTGAAGATAGCATGCAGAGTGGATTAACTAATATGGTTcagtaa
Protein Sequence: MENEEQEVEFHSTLEPDIIIDDSSRRAGRDFGPFEPISALQPRSWASHAKWRAFLWNCIWDDEFYENQQENARAELTNNLQKRIGPEVSLIPVKKSTIRVKMFSKMVEREPPPEPEEHKVQRIIHRSPRQTVRLISKEEMIQAETGCNSKRKSLPLEKCPICKKFFRRMKTHLQKHENVKRDPNDPLTCRYCMKVFNTGSNLSIHMRTHTGDKPYICEVCTKGFAQSCNLVNHMRIHTGERPFKCPHCDRAFTQSGNLSNHVRLHTDEKPFKCHFCDKAFTQSGNLNSHIRNNHKFVDNIEDSMQSGLTNMVQ

Sequence clustering based on sequence similarity using MMseqs2