Slut019529.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Sialis lutaria
Gene Symbol
L
Assembly
GCA_949319165.1
Location
OX439245.1:18804277-18812212[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.00023 0.012 16.2 6.3 1 23 76 98 76 98 0.98
2 22 0.24 13 6.7 4.6 1 23 104 126 104 126 0.97
3 22 4.6e-07 2.5e-05 24.7 2.8 1 23 132 154 132 154 0.99
4 22 0.00027 0.015 16.0 0.1 1 23 160 182 160 182 0.98
5 22 0.0011 0.062 14.0 1.3 1 23 310 333 310 333 0.97
6 22 2.5 1.4e+02 3.5 0.7 2 19 343 360 343 365 0.87
7 22 0.29 16 6.4 0.2 1 23 421 443 421 443 0.95
8 22 1.7e-05 0.0009 19.8 1.1 2 23 471 492 470 492 0.95
9 22 0.00033 0.018 15.7 0.3 1 23 500 523 500 523 0.93
10 22 0.019 1 10.2 0.2 1 23 528 551 528 551 0.92
11 22 5.4 2.9e+02 2.5 0.0 2 23 603 624 602 624 0.92
12 22 0.05 2.7 8.9 4.8 1 23 628 651 628 651 0.94
13 22 1.3 71 4.4 0.5 3 23 709 730 708 731 0.91
14 22 0.00017 0.0091 16.6 2.4 2 23 744 765 743 765 0.96
15 22 0.085 4.6 8.1 0.5 1 23 775 797 775 797 0.97
16 22 4.3 2.3e+02 2.8 2.3 2 23 805 826 805 826 0.93
17 22 9.2 5e+02 1.7 0.1 2 23 846 867 845 867 0.94
18 22 0.083 4.5 8.2 1.9 1 23 944 966 944 966 0.97
19 22 0.47 25 5.8 1.2 1 23 975 997 975 997 0.96
20 22 0.0028 0.15 12.8 0.3 1 23 1005 1027 1005 1027 0.98
21 22 3.2 1.7e+02 3.2 1.5 1 23 1034 1056 1034 1056 0.93
22 22 0.0032 0.17 12.6 0.7 1 23 1100 1122 1100 1122 0.98

Sequence Information

Coding Sequence
ATGATGCTCTTTAAAGGACACAGTCCCAGACTCGAACTGTTGATAAATAGGATACAAGCGTCTAGAGACTATCATTTATTCACACAGAGAAGAGATGTGTTAGGTACGGATGGGAGTAGCAGTTGGCGGTCAGAAACACCACCGACTCCGGCAACAACAGGCTCCGGTGTAGACTTAACTGAAGAAGAGTTAACGTTTACAGTGGGGACTACAGAATCCACTCCATATACTTGTCATTTCTGCAACAAGGCTTTTCCTAGACTTCATTATTTGAAGAAACATGAACAgTCCCATAGCGACGAAATGCCCTTTAAATGCGAATGGTGTTCTAGACTTTTCAAACACAAGAGATCTCGAGATAGGCATGTTAAACTTCACACCGGTGATAAGAAATACAGGTGCCCTCATTGCGAAGCTGCTTTTTCAAGAAGTGATCATTTAAAGATACATTTACGCACTCACGACAATGGTAAACCGTTTCAATGTGTTGTTTGTAACCGTGGTTATAATACAGCAGCTGCACTTACTTCACATATACAAAATCACAAAAAGCAACAGGTATCGGAAACCATTACCGGAAACGGAGATTCCCAATATCGTGAAGATACAAATTCATCATTAACCAACCACGAATGTTTGCAAacaCACGAATCAAACAGCCACGTGACACAGAGTGAAATACAAGTGGAAATATTTACGAGATCTGAAACCGTCACTACTACAGAGTCCATAACACCGAAATTGGCCTGTATATATTGCGCACAAGATACTTTTAACACGATGGAAGAACTACAGAATCACGTCGAATCGAATCACAAAGCTATTATTAATGGTGATATTCAAAAATGTTCACCAAGTTTACAACAAAAGCATTTTGCAACGTCCGCATCGTCGCCGTGTTCAGTATCGTCTCCAATCACTCCTACATTTTCTTGTAACTTGTGTACTATGAGATTTATGTCGTATCAAAATCTTCAAATGCATATTCTTACATCGcataagatatttaattttacaccTCAAGCTGTTTGTTCATATTGCTCCTTACCATTTAAAAGTATTGAAATGTTTGCTGAACATTGTGCCAAAGtacatagaaataaaataatagataatataCCTGAACAAATTAAACCGACGGATCTGAGTAAAAAGACCTATATCGATGAAAAGATGGCTAAAAGGATGAAAAAGAATGATGATATATTGTCGTCATCTTCAAGCACACCCACTAATTCACATTACGATAATTTTGGATTGTTTCTTTGTAACCAATGCGATGCAGGCCTTCCAGATTTCGAGTCTTTTAGATCGCATTTAAAATTACACATAGAACATTCAGACGGTATTAAAAATAACGTCGAACAACGAAATTTTATGATAGATATGCTAAAAGAATCAATGCTACTGCCTTGTCCTCATTGCGGTCAAAGTTTTAACGATCTAACTATGCTCGAGAGACATATATGTGGTCATTATTTCACTTCGATCACTGAGTACATGTGTCGTAGTTGTTCTAAAACATTTCCAAAAGCAGACGATTTACAAAAACACTTGTTAGACGCCCATGCATATCATTTATATAGATGTTCGGTGTGCAAAGAAATGTTTGACTCAAAAGTCGCTATACAGGTTCATTTTGCTGTTAAACACAGCAGCGAGTGTCAAATGCTGCGATGTTTGATCTGTCCATCAGACACACGCTCCGTGTTCCGTACAGAAAAGGCTAGCAAGATACATATTCGTACAAACCACGACAGTACTATCTTTATGACACCTCTACCGACAGCAGTAGGCAAACCACTACGTTGCAGCTTCTGTATCGCTGATTTTGACTCCGAAATAGACTTGCAGATTCATCTCGCTGTACATTTCCAGCCGTTCAAATGCACCATTTGTAACAAGTCTTTTCAAGTAGAGTATTTGCTAGAGTGCCACATGCAAGAGTGTCACGAAGTTAAAgtTTCCAACGGTCTCAACGAAGTCTTAGTAGACAGTAACCACGGACAAGATCCAATTAAAACTACCGATACGCCGTTTTTATTATCCGGAGCACCGAATAAACAGCTTCAAGTTGATACAAGTTCAAGTAATCTTGAATCTCCCAATTGCAAATCAAACAGTTGTGATATATGCGATCGAAATGATTTTAGCGAATCAGAACTAATTGCTCACAGAAAACTAGTTCACCATATCAAACCAACATCTAAGAACGGAGTAGTGAGTTTACACTGTGCTTACTGTAATGAAAACTTCAAATCAAGAACAGAACTTGAAAATCACATGAAAAATCATTCACAAAGTAGCGGTGTGTCCGGaaaacataaatgtaatatatGCGATGAACTTTGCCCTTCAGCAGCCGTATTGGCGGAACATAAGTTGACACACTGTAAAGTTATTTCTGGTAATTCTTGTACTCATTGCAAAGCAGTACTTTCAACTGACGAACagtttttttctcattttgtGAAACACTGTGGTACTACAAATAATACATCGAGTAACACTAACAATCAGATATCTTTACCGATGCCTTGTGTTATTTGTAGACAAACTCTCATGTCAAATATTGAAGTTAAAATACACGCACGATTCCATTTAAGAAGTAACAATTTACCAAATGAATATCAATGCGTTCTTTGTCTAAAGAACTTTGATAAGCCAAACGTGATTGTAGCAAACGGAAATTCAAATGATTGTTTTACTTACATATGTAGAGAATGTTACAGTCATCATAGTTTAGCAATGAATTATCCTGATcagaaaaatgatttaaaatgttCGAAAACCGCTACAGCTTTGATAGATTCaggaaataataataagtattcgTGCCTAAAATGTGAATTGAGTTTTGAAACCGAATGTCAAGTCCAAAATCATGTTACTTCACATTTACTCAACGATAAAAATAATGAGTACATATGCCATCTGTGCACAAGTAAATTATCTTCAgaattcaaattacaaatacatttaatagaaCATACATTTGTTGGGTTTGGAAGCTACACTTGTTACATATGTTCTACAGTTTTTACAGCATCCCAAGGATTGTATTCACATATGTTAGAACATGGCTTAGCTGCCAGACCATATGATTGCCCGAGATGCAGTTCCAAATTTTTCTTTAGAGCTGAACTAGACAATCATAGTTTCAGTCACATAGAGCACGATTCTTTATTAAGACAACAATCTGATATTGATTTATTGACAGGAGGTTacgataaaaatgttaatttattagaTCAAATAGGTGGATTATCGAATTACGAAAAACCTAATAAATCTTCATTTTGTTGTAACGAATGTCCCATCACTTTTCCAGACATTATATCGTTTTTGAATCACGTCAAAACACACGGCGTTACTAATGAACAACAAGAtactaaacaaaatacaacaatatATACCAAACAAGAAAGTGGTCAATGTATGTCGTCGTACATTGAGGTACAAGTAACATCTCCGCCGAAACAAAATGATGAAAATACCACCAGTTGA
Protein Sequence
MMLFKGHSPRLELLINRIQASRDYHLFTQRRDVLGTDGSSSWRSETPPTPATTGSGVDLTEEELTFTVGTTESTPYTCHFCNKAFPRLHYLKKHEQSHSDEMPFKCEWCSRLFKHKRSRDRHVKLHTGDKKYRCPHCEAAFSRSDHLKIHLRTHDNGKPFQCVVCNRGYNTAAALTSHIQNHKKQQVSETITGNGDSQYREDTNSSLTNHECLQTHESNSHVTQSEIQVEIFTRSETVTTTESITPKLACIYCAQDTFNTMEELQNHVESNHKAIINGDIQKCSPSLQQKHFATSASSPCSVSSPITPTFSCNLCTMRFMSYQNLQMHILTSHKIFNFTPQAVCSYCSLPFKSIEMFAEHCAKVHRNKIIDNIPEQIKPTDLSKKTYIDEKMAKRMKKNDDILSSSSSTPTNSHYDNFGLFLCNQCDAGLPDFESFRSHLKLHIEHSDGIKNNVEQRNFMIDMLKESMLLPCPHCGQSFNDLTMLERHICGHYFTSITEYMCRSCSKTFPKADDLQKHLLDAHAYHLYRCSVCKEMFDSKVAIQVHFAVKHSSECQMLRCLICPSDTRSVFRTEKASKIHIRTNHDSTIFMTPLPTAVGKPLRCSFCIADFDSEIDLQIHLAVHFQPFKCTICNKSFQVEYLLECHMQECHEVKVSNGLNEVLVDSNHGQDPIKTTDTPFLLSGAPNKQLQVDTSSSNLESPNCKSNSCDICDRNDFSESELIAHRKLVHHIKPTSKNGVVSLHCAYCNENFKSRTELENHMKNHSQSSGVSGKHKCNICDELCPSAAVLAEHKLTHCKVISGNSCTHCKAVLSTDEQFFSHFVKHCGTTNNTSSNTNNQISLPMPCVICRQTLMSNIEVKIHARFHLRSNNLPNEYQCVLCLKNFDKPNVIVANGNSNDCFTYICRECYSHHSLAMNYPDQKNDLKCSKTATALIDSGNNNKYSCLKCELSFETECQVQNHVTSHLLNDKNNEYICHLCTSKLSSEFKLQIHLIEHTFVGFGSYTCYICSTVFTASQGLYSHMLEHGLAARPYDCPRCSSKFFFRAELDNHSFSHIEHDSLLRQQSDIDLLTGGYDKNVNLLDQIGGLSNYEKPNKSSFCCNECPITFPDIISFLNHVKTHGVTNEQQDTKQNTTIYTKQESGQCMSSYIEVQVTSPPKQNDENTTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01343387;
90% Identity
-
80% Identity
-