Sful004038.1
Basic Information
- Insect
- Sialis fuliginosa
- Gene Symbol
- egg
- Assembly
- GCA_961205875.1
- Location
- OY540811.1:6141435-6149539[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 2.4 4e+03 -2.4 0.0 47 61 510 523 503 527 0.78 2 3 7.6 1.2e+04 -3.9 0.0 32 38 772 778 771 781 0.84 3 3 3.1e-09 5.1e-06 26.1 0.1 9 69 815 871 808 878 0.83
Sequence Information
- Coding Sequence
- atggCGAATCTCGAAGAATTTTTTAAACCTTCAACTAGTCAAGTTACCTTTAATGAAggtgaaaaagaaaaatatctcACGGATGTGCACGGGAAAGATAATATCACTAATGCCTTTGAAGTTAGTCGTAgcatattacaaaaattaaatctagTGGAGAGTTCATCAAGTGGAGCAGTAACTAGGAAAGCTCAACTTATGGGTGAGCTAATTGCCCAGTCTACAATAGAAGTTTTAGAAAACTTTGTTTTTGAAGATGAAGACGAGCTTTATTTACCAAATGAAGTACTACCAGAAGAAATTACGGTAGAAGCAAAAAGTGACGAGTTGGGCGAAGAAGAACTTGCACGTTCAGAAAACATGCCATCTCCTACAAAATCATCTCACAGCATAATAAGTGTTTCGTCCACTACTAGTACAGAATCGTCTGATGATTTTCAACCTCCTGAAGAAAAAAGGTCCAGGTGTTCCGATTATGTATctttagacaaaaaaattagaatagTTCAATTTGCCAAAGAACATCCTAATTGGAGCTTGAATACACTTCAAATGTCTGGATGCGCtgcactaaaaaaaaaagaatatctaAAGCGATGGATAAATGATATAGAACAAGGTGGTGGTGTTAAAGAAAAGTACGACATGATTAATAAATGGACATTTGATAGATTTTGTGAAGCACGAAATAATAAAGAGCCAGTTACGACGAGGATGATTCAACAGTGGGCTACTGCTGCAGCGATGCAGTATAAAtcagataattttaatttcacgGCGTCTAGCTCAtgggtaattaaatttaaaagcatCCACCAAATTCGTCAACGAAAAGTAACACactatataaaatcaaaaaaagcaATGGATTTATCGACAATCTTGATGGAAGCTGACAAATTCCAGAAaagaatttctaaaaaaatttctaaatttaatGCTAAATTTGTCATCAACACCGATCAAACGGGATGTGAATATAGATCAGATGTAAAACGAACGTTGTCATATAAAGGAGAAAAGGCTACGGATGTGTTTCTGGGCGATTTCAATAAAGTTACGCACAGTTATACTGCACAGTATGCTTTGACTGCTGCAGGGACACTTTTACCTAAAGTTTTTCTGTGCATGCAAGAAGCAAATGGTACTTTTGGGCCTCGTGTACGTGAAAATGTACAGTTGCTAGAGAAAAAGTATAACAATGTATTTGTGACAGCTAGCAAGTCAGGGAAATTAACAAAACAGCATTTCAGcaattttgttgaaaatataatCAGTCCATATTGCGAAAAGGaggaatttttaataatattagatTCATGGGGAGGACAAACAGATCCTGCACATTTTAACAGTGTGTTCACAGATGAAGATGGTAACTGCACGGCGACTGTGGAAATTATTCCTCCGCATTGTACTCCATTCTGTCAACCTTGTGATGTGTACTTTTTTCGGCaaTTAAATGACAAGATCCGGCTGGAAGTAGACACATACCGTGTCCAATTTGAACCCTCGGGGAAGGTCCCGCAGCAAGTGATCAAATACCTAAATGCAAAGCAGCTGGCATACTTAACCCCTTGTCCCGTGAAGCTAATAATCGGCACTAGAGTCATCGCTGTCTTCTGGAACGGCGAGTCTCACGTCAGAAACATGTATGCCGGGATCATAGCAGAACCAGCGTCTTCTCTCAACAACTACAGGTACTTGGTATTCTTTGACGATGCATATGCTCAATATGTTCGGCACGAAAACGTCCGATTGATAATCGAAGAGAATATCAACGTTTGGGAAGATCTTCCGCCGAAAACAAAAGAGTTCATTCAGAGCTATTTGAAGGAGTATCCTGAAAGACCGATGGTCAAATTGACGAAGGGGCAGATCGTTCGCACAGAAAGAAACGGACGTTGGTGGCCGGCTAAAGTGGTTGAAGTCGATGCGTCTTTAGTTTCGATGCTTTTCGAAAACGATAACCACAAAGAATGGATCTATCGCGGTTCTAGAAGACTCGCGCCTTTGTACACGACAAATCAGAACCAGATATTGCGACAGAGCCGAGGTTTAATTACACCTCAACGACGTCTCCCGATGAAAAAACACGGGCCATACGTGGAATACACAAGACCCATAGAAAGCATAGATTTGAGTAAAGACGACGAAACTACACCGAAAGTGTCAACGTTACCTGAGCTCCCGTCTGTGCCCAGAGCCGTAGCCAAGAAGAGTACAGCTTCATCGCTGTCTTCTGTAATCAATAAACAGCCATCAATGACGATGGTTCCGTTCTTACCAACGGGAGGGGTTCAGCCGATGAGTAAAGTTATTtattatGCGCCGAGAACTGAAACCCAGCCTCAGCTGTACAGACCTCATACGTGTGGGCCCCTGTGTGCTAAGAAGGCCAAGAAAAAACTCAACGAACTCAAGGAGTACAGTATTCTTATGAAACCTATTCTTGCTGGATGGTtcagggcATGCGTCCGTTATTCCAAGAGCAAACGTGAGATACGCTACGTAACGCCCTGTTCTCGTGTCGTTCGAACAATGCAAGAACTGCATTTGTACCTGCGAATAACCAAGAGCGAAATGTCCGTTGATATGTTTGATTTCAACTTCTGGGTGCACATCTTGGCTGAATTCTCTTTAGAGAAGACAATTATAAGTATTCCTGATTTATCTCAAGGACGAGAGCAAGTACCTATTCCTTGTATGAACTACGTGGATGGGCAAGTTCCCGAGCCTTGCAGGTACACGACTGAACGTGAACCCACAAAAGGTGTTAACTTGAACCTCGATGAAGATTTCTTGTGTAGTTGCGACTGTACCGATGACTGCCAGGATAAATTGAAATGTGCATGCTGGCAACTGACACTCGAAGGGACTATGTTTGGGAAGACTAAATCACCAGATTTAACCATCGGTTACGTGTACAAGCGATTGTTAGAACCAGTAATTACAGGAATCTACGAATGCAACAAAAGATGTAAATGTGCTAGCACTTGTCTAAACCGAGTAGCCCAGCATTCGCTATCTCAGAAACTGCAAGTGTTCAAGACATCTAACCGTGGTTGGGGTATCCGATGTTTGAACGACATACCTCAGGGCTCATTTATCTGTATATATGCTGGACAGTTGCTGACTGAACAAATGGCAAAcgagGGTGGCAAACATTTTGGAGATGAATATCTAGCTGAGTTAGATTACATAGAAGTCGTTGAGAGGTTGAAGGAAGGTTACGAGTCGGACGTACAAGAAGATGCCACAGAAGCGTCTAACGGTAGCAGAGAATCGCAGGAAGATGAAAACATGGAAGATGAAGATGATGACGATGAAGAAAGTAATAAGAAGAAAGATAAAACAATGGAAGATTctgattttatttgtaatattccGTCAACGGCTCTGAGCGAATCAACTTACAGGACTAGATTCAGATCAAGAGCAAACAGTAACAGTACAGAAACATTCGAAGGCGAATCAGAGAAGTCAGATAAGTCAGAGAAAGCAAGCAGCGATATCGATGAAAATAAACAGAAACCTGATGAAAAGGAAGTAGAAGTTACCAAGATCAAAGAAGAACCGGTACAGATACAGATTATGGATGAAGATTGCATCACAATCACAATCAGTGATGATGAAGAAAcAACAAGAGAACCTTCGAGTTTTATTCCTACGGCGGCGGCTGAAGATAACATGGAAGTTAAACACAGGTCTGTAAGATCTATGTTCGGTGAAGGGGAAGCTTGCTACGTCATGGATGCCAAAATAACTGGAAATATCGGACGATATTTGAATCATTCTTGCAGTCCAAATGTTTTTGTACAGAACGTATTTGTCGATACACATGATATAAGGTTTCCGTGGGTGGCGTTCTTTGCTCTGACGTACATCAGAGCGGGCACAGAACTCACGTGGAACTATAACTACGATGTCGGTAGTGTACCTGGTAAAATAATGTACTGTCATTGTGGAAGTGATGAATGTAGAGGACGGTTGCtgtag
- Protein Sequence
- MANLEEFFKPSTSQVTFNEGEKEKYLTDVHGKDNITNAFEVSRSILQKLNLVESSSSGAVTRKAQLMGELIAQSTIEVLENFVFEDEDELYLPNEVLPEEITVEAKSDELGEEELARSENMPSPTKSSHSIISVSSTTSTESSDDFQPPEEKRSRCSDYVSLDKKIRIVQFAKEHPNWSLNTLQMSGCAALKKKEYLKRWINDIEQGGGVKEKYDMINKWTFDRFCEARNNKEPVTTRMIQQWATAAAMQYKSDNFNFTASSSWVIKFKSIHQIRQRKVTHYIKSKKAMDLSTILMEADKFQKRISKKISKFNAKFVINTDQTGCEYRSDVKRTLSYKGEKATDVFLGDFNKVTHSYTAQYALTAAGTLLPKVFLCMQEANGTFGPRVRENVQLLEKKYNNVFVTASKSGKLTKQHFSNFVENIISPYCEKEEFLIILDSWGGQTDPAHFNSVFTDEDGNCTATVEIIPPHCTPFCQPCDVYFFRQLNDKIRLEVDTYRVQFEPSGKVPQQVIKYLNAKQLAYLTPCPVKLIIGTRVIAVFWNGESHVRNMYAGIIAEPASSLNNYRYLVFFDDAYAQYVRHENVRLIIEENINVWEDLPPKTKEFIQSYLKEYPERPMVKLTKGQIVRTERNGRWWPAKVVEVDASLVSMLFENDNHKEWIYRGSRRLAPLYTTNQNQILRQSRGLITPQRRLPMKKHGPYVEYTRPIESIDLSKDDETTPKVSTLPELPSVPRAVAKKSTASSLSSVINKQPSMTMVPFLPTGGVQPMSKVIYYAPRTETQPQLYRPHTCGPLCAKKAKKKLNELKEYSILMKPILAGWFRACVRYSKSKREIRYVTPCSRVVRTMQELHLYLRITKSEMSVDMFDFNFWVHILAEFSLEKTIISIPDLSQGREQVPIPCMNYVDGQVPEPCRYTTEREPTKGVNLNLDEDFLCSCDCTDDCQDKLKCACWQLTLEGTMFGKTKSPDLTIGYVYKRLLEPVITGIYECNKRCKCASTCLNRVAQHSLSQKLQVFKTSNRGWGIRCLNDIPQGSFICIYAGQLLTEQMANEGGKHFGDEYLAELDYIEVVERLKEGYESDVQEDATEASNGSRESQEDENMEDEDDDDEESNKKKDKTMEDSDFICNIPSTALSESTYRTRFRSRANSNSTETFEGESEKSDKSEKASSDIDENKQKPDEKEVEVTKIKEEPVQIQIMDEDCITITISDDEETTREPSSFIPTAAAEDNMEVKHRSVRSMFGEGEACYVMDAKITGNIGRYLNHSCSPNVFVQNVFVDTHDIRFPWVAFFALTYIRAGTELTWNYNYDVGSVPGKIMYCHCGSDECRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -