Basic Information

Insect: Shargacucullia verbasci
Gene Symbol: Zfa
Assembly: GCA_947562105.1
Location: OX387284.1:4904602-4913158[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0044 0.33 11.8 1.0 3 23 699 720 698 720 0.96

2 23 0.31 24 5.9 0.3 1 22 1105 1126 1105 1126 0.95

3 23 6.8 5.1e+02 1.7 0.4 1 22 1168 1189 1168 1191 0.82

4 23 0.0021 0.16 12.8 2.4 2 22 1201 1221 1200 1221 0.94

5 23 0.98 74 4.4 0.0 3 23 1230 1251 1228 1251 0.89

6 23 0.016 1.2 10.0 0.2 3 23 1272 1293 1270 1293 0.96

7 23 0.0034 0.26 12.1 3.5 1 23 1299 1322 1299 1322 0.95

8 23 0.11 8.6 7.3 0.0 1 23 1348 1371 1348 1371 0.90

9 23 0.005 0.38 11.6 3.5 1 23 1376 1398 1376 1398 0.97

10 23 0.0078 0.59 11.0 0.2 1 23 1404 1427 1404 1427 0.95

11 23 0.0021 0.16 12.8 1.3 1 23 1440 1462 1440 1462 0.97

12 23 0.00016 0.012 16.3 1.8 1 23 1513 1536 1513 1536 0.97

13 23 0.0043 0.33 11.8 1.7 1 23 1596 1619 1596 1619 0.96

14 23 0.0022 0.16 12.7 2.1 2 23 1646 1668 1645 1668 0.95

15 23 0.079 6 7.8 0.1 2 23 1674 1696 1673 1696 0.93

16 23 0.009 0.68 10.8 0.2 1 21 1740 1760 1740 1761 0.95

17 23 0.00038 0.029 15.1 1.0 1 23 1771 1793 1771 1793 0.93

18 23 0.0001 0.0077 16.9 0.3 2 23 1887 1909 1887 1909 0.93

19 23 3.6e-07 2.7e-05 24.6 1.4 3 23 1916 1936 1915 1936 0.98

20 23 0.02 1.5 9.7 0.3 1 23 1955 1977 1955 1978 0.95

21 23 0.17 13 6.8 0.0 1 23 2000 2022 2000 2022 0.97

22 23 0.025 1.9 9.4 0.6 1 23 2028 2051 2028 2051 0.95

23 23 0.00023 0.018 15.8 0.4 1 23 2059 2082 2059 2082 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0044	0.33	11.8	1.0	3	23	699	720	698	720	0.96
2	23	0.31	24	5.9	0.3	1	22	1105	1126	1105	1126	0.95
3	23	6.8	5.1e+02	1.7	0.4	1	22	1168	1189	1168	1191	0.82
4	23	0.0021	0.16	12.8	2.4	2	22	1201	1221	1200	1221	0.94
5	23	0.98	74	4.4	0.0	3	23	1230	1251	1228	1251	0.89
6	23	0.016	1.2	10.0	0.2	3	23	1272	1293	1270	1293	0.96
7	23	0.0034	0.26	12.1	3.5	1	23	1299	1322	1299	1322	0.95
8	23	0.11	8.6	7.3	0.0	1	23	1348	1371	1348	1371	0.90
9	23	0.005	0.38	11.6	3.5	1	23	1376	1398	1376	1398	0.97
10	23	0.0078	0.59	11.0	0.2	1	23	1404	1427	1404	1427	0.95
11	23	0.0021	0.16	12.8	1.3	1	23	1440	1462	1440	1462	0.97
12	23	0.00016	0.012	16.3	1.8	1	23	1513	1536	1513	1536	0.97
13	23	0.0043	0.33	11.8	1.7	1	23	1596	1619	1596	1619	0.96
14	23	0.0022	0.16	12.7	2.1	2	23	1646	1668	1645	1668	0.95
15	23	0.079	6	7.8	0.1	2	23	1674	1696	1673	1696	0.93
16	23	0.009	0.68	10.8	0.2	1	21	1740	1760	1740	1761	0.95
17	23	0.00038	0.029	15.1	1.0	1	23	1771	1793	1771	1793	0.93
18	23	0.0001	0.0077	16.9	0.3	2	23	1887	1909	1887	1909	0.93
19	23	3.6e-07	2.7e-05	24.6	1.4	3	23	1916	1936	1915	1936	0.98
20	23	0.02	1.5	9.7	0.3	1	23	1955	1977	1955	1978	0.95
21	23	0.17	13	6.8	0.0	1	23	2000	2022	2000	2022	0.97
22	23	0.025	1.9	9.4	0.6	1	23	2028	2051	2028	2051	0.95
23	23	0.00023	0.018	15.8	0.4	1	23	2059	2082	2059	2082	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTCGAAAATCAAGGATTGCGTGTCTGTTCAGATAAACGAAAATGACGACCTGCCCACTAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGGCATGTTTTTAAAAATGTATGTGAAAGGACACAAAACAAACTACAGTCTCTAAAAGATGGCAGCCAACTAGAAGAGGTGAAAATAAAAAGTGAACCTTTATCTGATGGGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGACATTGAGAATACTGGCTTGTCAAACAAATTACAGCCTGAAGGTCCACCTATTTTGGCATCATTGGGGCTCACACCGAGGAGTGATAAGAAATGTGTGGATCCTCGAATGGATTGGCATCGAGTCCATGCAATTTTGGATATGGTTCAAGACAATGAGGTGATTGATTCTCTACAGACAAAAGAAGAGTGTGACATTTTGCAGCAATCTGACCATGACTCAGACACAGAGGCCGAACTCCAGCCAGAAATTGATGATGACTTTGTTGACTGCAAAATTGGATATATTTGCAAAAATAAAAAAATGATATCGAAAAATCCAAAACTATCGACATCTGTAAATAATGCTAGAATCAAAGAAGCTTTCAAACTTCGGAAACGTAAATCCGATTCACGTAAACATTGTTCACGACCTAAAAATGCGTGGCAATTGTTATTCACTGATGACCTACTAGAATTGATTGTTGCATCTACTAATGAAAATATTGTCACAAATGGGAAAAGTTTCTCAGAGTCGACTAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATTTACACGGCATAATGCGGCCGACGCATCAGAAATGTGGTGACCTTTGGAACGGTGAATGTGGTGTACCTTGCGTTAGAAATGTCATGAAATACGAAAGGTTTAAATTCCTGCTTCAAAACATCAGTTTCGATAAAGAGGACGACGACAGCATTATACAGTTCGACATAATGAAGCGTATGCGTAAAGTATTCGAAATATTCGCCATGAATTGTAGAACATCTCACGAGATCGAGAATATTGCGGTTATTGATGAGATCATCGTGCCAGTTTACGGACCTTGCCCATTTCGATATGATATTGATAAGAAACAGCTGAAGCGGGGTATAAAAATTGTATTGCTTGTAGACTCATCAACGTTCTATATAAGCAATTTAGATGTCATAACTGATCCTTATTTTGGTGCCGAAGAGATAACAAAGAAGATGGTTCAACATTTAGCCGGCACTGGAAGATCGATTGTTATGGATAGTTGGTTTACATCCTCTACATTAATTGAAACTCTTAGAAACGAGTACCAGTTGTTTTCTATAGCAGCTTTGAATCCGAAGTGTGATATGATTCCACCGCTATTTCTATCACAGTATAGAAAATGTCGAACATTCATGTCTGGATTTATTGATCATGAAGTATCACTCACATTTTATGTCAATTCTGAAGGGAAATCAGTCAATGTTTTGACTAATGAGCCGAGATATTACAGGAAGGGTCATATAAACCACACTACAGTTGTATCAGTGTATAAGAGGAATCAGTCAGCAGTAGAAGTTGTCGATGTTCTTATGAATTACTACACTACTATGCAACACACAAATAATTGGACATTGTCTTTATTCTTTACATTGTTGAACATTGCTTCGGTCAATGCTCAGGTGTTATGGTGTTCTCAAAACACGAATATAACACAGCGTCGCTTATTCATCAAAGATTTGGCTTTGAGCCTATTGGAACAAGATGAAGAACGGATTTCAATATCTCCGCTAAACGAGATAGAGGATAAAAAGAGCAAATTCTCTCTGGGAGGGGAGAGCGAAAACAATGAAGAAGAAGAGGAAGAAATGAACGAAACCGCTCAAACATACCCAAAAGTGCCTCATATGCCGGAGGTGTCCATCACGGTGATGCGGCCCACCGGGGAAACACTGCACGCTCGCCAGGGCATTCACCAACTCGCCTCCAAAGACTGTCTCGTATGCGGACGATCCTACAGGTACTCCCACAATGCCCGTCGACATGAACTTACTGCTCACAGTTTTGATAGGTACACAAACAAAATAACTCCTAAAAAAACCCTTACTCACCTACAACCCAAACTTAGACCCAATCCATTCAACCCCAAAGCACGGATGATGCCTAATCCTATTAGTCATAAGATGCAATTCATGAACAAGAACATGCCACCAAAATTAATGCCTATAAACAAAGTAATAACGCCACAGAAGCCCATTCCAATAAAGTCGTCAAAGACGCCACAGCATAATTTACCTTATCCTCTGCGAATTAAAGCACTCAAGGATTTACAAATAAAGAAAAAGGAACCACAGATTCTGAAAACTTTGCTAACCTCTAAACCTGAAGTTCTGGTGTCAGAACCTGAGATTCTAAATTCTGGTCCAGAAAGTCCAGAAACATTGATATCTGAACCAGAAATAGCATCTTTTCAAGTGGAAGCTATTCTTTCCGAACCCGATCCTGATGCATACGATCCTCAGCAAGACGAAGAAGGAGATGGAGAAATGCACAACAATCAAAGTCAAAACTATGACACAGTGGATATGGACTCTGAAAATGAAATTGAGATTGCTCGTCAGCATGGTATTGAACAAGAAGGCGAAGAAAATGCAGATGGTGACGAAAATATGGAACAGTGTGATGATGAAAACAACATGGAAGAAGGTGGTCAGAGCGACAACGAAAAAGATGGAAATGATGATACAGTAGAAAGCCAAGAAAACATGGAAGGGGATGATGATGTTGATATAAAAGCTGAAAGTGAGGTCAAAGACGACGAAGGCCAAGAGGAAAGAGATCATGAAAATATTGAGATGAATCATGATAAAAACGAGGACGAAGACGAAGATGACCTTCCAATATCATTGGCGCCAGTCGTCGAAATAAATGAGGATTTGCAAGCCAACTCATTCAACAGTGAAGTAAACGAAGAAGAAGAGGAAATGGACGAAACCGTCGATCCCAATGAGACTATCGAAGAAGAGGAACAGGTCAAAGAACTTGACCCTGACAAAACATACGTCACAAAAACACAAAGAGACTTCATCCAAAAATATCGTGACATTATACAGCAAATTAATACGAAGCGCTGTTTATGCTGCGATCGGGAACATCCGCGCAGAAAAGCTGTTATACAACATTTGCAGAAAAATGGACACAAAGTCCCAAAGCACACATGCTACAACTGTGTGGTCACATTTGGACATATTGGCGCCTTACTCAGCCATATGAGGTCAAATTCTTGCACTAATTTGTGGAAGATTATTTATAATGAAAATGGCATTACTGATGACTTGGTTCTAGAAGATGAGCCGAAAGAGGTCAAGGTTCAATATAAAGATATTTTTAACGCTAGATCATATGCATGCAAACTCTGCCCGGCTAAGTTCCAACTGAAACAGTTTATAATGAAGCATGTTTTAGATACACACGAAGATGGACAATCTAGGGTGCCACTCAGTTGTGTTCATTGCCGTTCTAGGTTCAAAGACAAAAGTTTACTAAAGAAACACATTCGTAAAGGTGACTGTACAGTTTATATTGCCTGCGATTTGTGCCCAGAGAAGTTCGGTAATATGCAAGACTTTAACGACCACGCTTTAGCTGTCCATGCTGGCAGTTTCGATCAGTCGGACAATCAGAGCAAATGTGTTGACGGTCGGCCAACTGACTGTCCGTTGTGTGGAAAGAAAAACAGCAGCTATCCGAATTTAGTGAAACATTTGAAGATAATACATAGCGAGGAAAAACCTCATTACTGCCAGCATTGTGACTCTAAATTTGAACAAGCTACCGATCTCAACAAACACATTTACATGGAGCATTCAGACAGAACATTGGGCATGTCAACCGCTGAACCAGATATGTCAATTGTGAAGGAAGAAGCGGAGGAGTATCACTATTCGTGTACGGAGTGTAATGCCATATTCGAAACTGTCGATGCATGGACAGATCACCAAGTGGCCGAACACAACCAAGTGGCCCACCATTGCGACCAGTGTGACAAGAAATTCTTGCGTCCTTCGGAGCTCGCGGAGCATAAGAATACTCATTTGAGGGTCAAATTTTATCCTTGTAGTGTATGCCCCAACTCTTACAGCACTCCTCAGAAACTGTCCGAACATGTGCAACAGTCGCATCCTGGAATTGGCTCCGTTGCGGCTGCTGAGACTGAATTTTTCTGTGACATCTGTATCAGATCATTCAAAAGTCGCCAAGCATACTCTAATCATATGCGTATCCACGCTAAAGTACCTACAACGAACAGGAAACCAGGAGAAATTATTAAAGGAGGTTTTGCTCCGCAAATTATCGGCAAACCTATTAAACAATATCCCATGGTGCAACCTGGTTTTGTCTCATTCAAACCAAATTATAATATTCCTAATGCTCCATATTCATGTGACATTTGTGGCAAAGGATTCATGCATAAGAAAAATATATGGAAACATAAGAAAGTGTTGCATGCTGACATTTTAGTTGACAGACACGATAGTGAAGATAATACTATGCAAGCTTCCACAGAAGAGGAAGAGTTTAATCCCGATGAAAACGGCGCCATTCTCTCAACGCCACAGTTTAACAGTTTTAATTTTACGAATTTCCCAAACAATACTCAACAAACGTCTCAAGAAGCAATGCCTTATTCGTGTGAATTATGTTTCAAACGATTCCCACTTAGGACTAGTTTGTGGAAACACAAACGCGCTAAACACGGAATTGTAAATGCTAGCGCCAGCGGCAGTAACGACACCGCCACGCAATCAGCCAGCGGTGAGGGCAGTAGTAGGTCTAGTTGCACTATATGCCGAATCACGTTTTCAGACAAGAAGTCTTACTATCGCCACCGAAAGAATGTCCATAAATCCACCGTTCAAATGTGCAAAATATGTGGCAAACCTCTAAATTCTACCTTGGAATTATATGAGCACTTAAAGGCCGCACACGCCAGGGAATTACTGGGCTATAATGCTAACCAAGGTTCCAGTAAATCTCAAGAAATGAAACAAGAGATAGAACCCGATTATGAAAATGATCAGGAGTCAGTCGATCCTAGTGTCGATTATCAAGCGCGTTACCCGTGCGACACTTGTGGCAAACAATTTGTTGGATTATTAGCTTTGCAGAACCATCAGTGCATTAATCAAATACCAGCACAGCCACAAACATTTGACTGTGAGATTTGTCATAAGAGTTACACTTCCATATCTGCGTTAAAATCCCATCGCGGCTGGCATTTGCGTTCCCCTGATGGGAAAGCAGCTGCTAACAACAGCGGACTTTGGATGCCTCAGCACAAAGTAACCAGCAAGATAAGCAAACATGAAGTCATCGATCCGTCACAACTTGCTAAGGTCACACACACTCCCGTTCCCTCCCCCGCTCCCGCTACCGCTACTGTAGCCAAAAGAAGACTTCCACCTGAGGTCGAAGTGACAGTTGTTAATCCAAACAAGAAATTGCGCTCTGACGACTCAGTTGAGTTAGAGCAAAACTCTGGTTCAATGGAGGATAGGTACTGCACGATTTGTGACAAAGAATTTACAAAACGAGCGGCGTATCAGCGTCACATGGACGAGGTGCATCAACCGAACTCAGTGTTTTGTCCGGTTTGTGATAAGAGCTTTACAAGGAAGTCCACACTGCTCATTCATATGAAGAAGCACTACGAGAGTGGTGAGGGCAGTTCCTCTGCGACTGGTCAAGGGGACGACGATATGTACTCGTGCGATTTGTGTGGCGCTCAATATGATAACGACCAAGCGCTGAGGGCGCACCGGGCGAGGCACCACGGAGAAGATGAGTCAGGGGAAGAGAGCGACGACGGCAATGTTCCCCTGGCTCAACCCGGAGAATTCACATGCGCGCAGTGTGGAGATGGCGTTGCAACTCCAAGAGACCTTATCGCCCATCGCACAATGCACGCAACTCCCACCAAATTTTTCTGTAACATTTGCAAAGTGTACTTCGCACGGGCGCTGGACCTCTCCTCACACACTCGGGCGCGACACGCTGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGCGACAGATTTTATATGAACAAGAAGAGTTTGCAACGGCACATCGAAATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLQSLKDGSQLEEVKIKSEPLSDGAYDDGVVIDGSYPDIENTGLSNKLQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTKEECDILQQSDHDSDTEAELQPEIDDDFVDCKIGYICKNKKMISKNPKLSTSVNNARIKEAFKLRKRKSDSRKHCSRPKNAWQLLFTDDLLELIVASTNENIVTNGKSFSESTSVSEIKTLIGILYLHGIMRPTHQKCGDLWNGECGVPCVRNVMKYERFKFLLQNISFDKEDDDSIIQFDIMKRMRKVFEIFAMNCRTSHEIENIAVIDEIIVPVYGPCPFRYDIDKKQLKRGIKIVLLVDSSTFYISNLDVITDPYFGAEEITKKMVQHLAGTGRSIVMDSWFTSSTLIETLRNEYQLFSIAALNPKCDMIPPLFLSQYRKCRTFMSGFIDHEVSLTFYVNSEGKSVNVLTNEPRYYRKGHINHTTVVSVYKRNQSAVEVVDVLMNYYTTMQHTNNWTLSLFFTLLNIASVNAQVLWCSQNTNITQRRLFIKDLALSLLEQDEERISISPLNEIEDKKSKFSLGGESENNEEEEEEMNETAQTYPKVPHMPEVSITVMRPTGETLHARQGIHQLASKDCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLTHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNMPPKLMPINKVITPQKPIPIKSSKTPQHNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILSEPDPDAYDPQQDEEGDGEMHNNQSQNYDTVDMDSENEIEIARQHGIEQEGEENADGDENMEQCDDENNMEEGGQSDNEKDGNDDTVESQENMEGDDDVDIKAESEVKDDEGQEERDHENIEMNHDKNEDEDEDDLPISLAPVVEINEDLQANSFNSEVNEEEEEMDETVDPNETIEEEEQVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVVTFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLSCVHCRSRFKDKSLLKKHIRKGDCTVYIACDLCPEKFGNMQDFNDHALAVHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHSEEKPHYCQHCDSKFEQATDLNKHIYMEHSDRTLGMSTAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCDKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGSVAAAETEFFCDICIRSFKSRQAYSNHMRIHAKVPTTNRKPGEIIKGGFAPQIIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEDNTMQASTEEEEFNPDENGAILSTPQFNSFNFTNFPNNTQQTSQEAMPYSCELCFKRFPLRTSLWKHKRAKHGIVNASASGSNDTATQSASGEGSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLNSTLELYEHLKAAHARELLGYNANQGSSKSQEMKQEIEPDYENDQESVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIPAQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVIDPSQLAKVTHTPVPSPAPATATVAKRRLPPEVEVTVVNPNKKLRSDDSVELEQNSGSMEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDMYSCDLCGAQYDNDQALRAHRARHHGEDESGEESDDGNVPLAQPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00050143;
80% Identity: -