Basic Information

Gene Symbol
Bgb
Assembly
GCA_949820665.1
Location
OX463303.1:10881799-10883566[+]

Transcription Factor Domain

TF Family
CBF
Domain
CBF_beta domain
PFAM
PF02312
TF Group
Beta-Scaffold Factors
Description
Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.9e-34 8.4e-30 104.9 0.0 92 163 46 118 26 122 0.92

Sequence Information

Coding Sequence
ATGAAACTCAATATGGCGAAGTGCAGCCTCGCGGGAAAATGGGGTGGTTTTTCCCCCTTTTCCCGGTCCCCTGAAATCAATACGAGCGGGCAGGGGAAGGCGGGCAATCGGAGGGCGCCGCCCGCCCAACAACATGGCCGCCCGGTACACATCGTCTCCCGGTTCATAATGAATGGCGTGTGCGTCCGATGGCGGGGGTGGTTGGATTTGGAGAGATTGGACGGGGCTGGGTGTCTCGAGTTGGATGAGGAGCGTGCTGCGATGGAGGATGCGGCGTTGCGTGAGCAGATCGAGCGTTATAACCAGCGGCTGCGTGACTTTGAGGACAAGCAGCGCGCTTACCGCGAGCACGGCGACGAGCTGCGGCACTCGCATGCGCACGCGCAGCGCTGCCACCAGCCGCGTCAGCCGCCGCACGCCACGCACCCAACACACCCGCACCCGGCGCACCCCGTGCACATCAAACCTCACTCACAGGGCGCTCTTATCTCGTAA
Protein Sequence
MKLNMAKCSLAGKWGGFSPFSRSPEINTSGQGKAGNRRAPPAQQHGRPVHIVSRFIMNGVCVRWRGWLDLERLDGAGCLELDEERAAMEDAALREQIERYNQRLRDFEDKQRAYREHGDELRHSHAHAQRCHQPRQPPHATHPTHPHPAHPVHIKPHSQGALIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00751785;
90% Identity
-
80% Identity
-