Spec004213.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Schizotus pectinicornis
Gene Symbol
BTBD19
Assembly
GCA_951805265.1
Location
OX638203.1:17485964-17491447[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1e-14 2.6e-12 47.0 0.0 2 108 30 147 29 149 0.90

Sequence Information

Coding Sequence
ATGGGATCGAGAGTGGGCGGGCTTGGCACTGCCGGTCTGCCCGCTGATAAAGCTCTAGCAGGAGTTCCTCGGCTGCTGGACGACCTACAACGACTATCTGAAGACAGTGATTCGGCTGATATAGTTTTTATCCTAGGAAGAGAGGAAGAACGGGTATTCGCCCACAGAGTCATCCTGATGGCCAGATGCAAGAGTTTTCAAACGGCGAAACGCGGAGAAGTCTGTCGCATCCCTGGATGTTCGGTGTCTCCTGCAGCACCAGGAACACCAACTCCAGTTCGACTTCCGCAAGCCCCTCCTGACACCTTCAAACAGTTCCTGCTGTACGTTTACACGGGAAAGATTTTGCTACAAGATAGCGGTGTTTTCGAGATGCTGGCGTTGGCCCAGGAATTGGGGGTTGATGAGTTGCGGAACGCCTGCGAGGACCATGTGACCTCAACTTTGTCGGTGGCTTCGGCGTGCACCTTCTTGGCCGCCGCCATGGAGATCCAAGACAGATCACCGGGAGGAAAGGCAGCCGCTGGTTTTGTCGGTCGCTGCGTCAGCTACATTGGAGAGAACGCCGTCGAATGTGTCCGTACCAACTCTTTCATGTCATTACCAAAGGAAGCtgttatcaaattaatttcttcagaCTACTTATGCTTAGAAGAAGAGGATGTGTGGCGGGCAATTCTCAATTGGGCAAAGTATCAAGCGGGAGTTACCCAACCGACCGCTCACTGGACTGAAGAGGAGAGGGCAAGAGTTTGCCAGCATCTTTCCCACGTCATCAACCATGTGCGTCTATTATTAATAGATAGTCAAGTTTTTGCCGAGGAGGTTGAGCCTACTGGCGCTGTCCCTATGGAGCTGAGCCTTGAAAGGTACAGGCATGCCGCTCTCCCAAGCAAATATCCAGAAGGTTCTGAGGATCAGAGGCTGCGTCCCAGGATATCGCCACATTTATTTCCGGGGTCACTGATTCTCGGCCAGGATAAAAGCCACTATCAAAGGATCCTGAATGCGTGGTTTGGACACCCTAAACAAAGTTGGCGTCTGGTTTACAGAGCCAGCAGTCACGGCTATTCCGCTTCAGCTTTCCACAGGCACTGTGACGGAGTGTCACCTACTTATGTTAtagttttgGGGACCCGGGGGGAGATCTGTGGCGGTTTCAGCGACGCCGCTTGGGGCCGGCCTCCCGGTAAAAGCCACTACGTGGCGTCCGAGAGAGCCTTCCTCTTCACTCTATAcaaccaccaagatctgccaCCTTCTCAGTTTCACCTGGTAAAGAAACCTTTTGCCATCTGCTACCACCCCGATTCCGGACCCATCTTCGGGGCCGGTGCCGATCTTTTAATATCGAGCAATTGCAACAGCAACATGGACAGTTATTCAAACCTGCCACACTCATATGACGGCGACGGAGCGTCACCAGCTGTGCTAATGGGCGATTACAATTTTACGGTAGCGGATTACGAAGTATTCACCCCCTTGGGTGCTTCAGGAAAACATCATAAAAACGAGCGGTATCAATGA
Protein Sequence
MGSRVGGLGTAGLPADKALAGVPRLLDDLQRLSEDSDSADIVFILGREEERVFAHRVILMARCKSFQTAKRGEVCRIPGCSVSPAAPGTPTPVRLPQAPPDTFKQFLLYVYTGKILLQDSGVFEMLALAQELGVDELRNACEDHVTSTLSVASACTFLAAAMEIQDRSPGGKAAAGFVGRCVSYIGENAVECVRTNSFMSLPKEAVIKLISSDYLCLEEEDVWRAILNWAKYQAGVTQPTAHWTEEERARVCQHLSHVINHVRLLLIDSQVFAEEVEPTGAVPMELSLERYRHAALPSKYPEGSEDQRLRPRISPHLFPGSLILGQDKSHYQRILNAWFGHPKQSWRLVYRASSHGYSASAFHRHCDGVSPTYVIVLGTRGEICGGFSDAAWGRPPGKSHYVASERAFLFTLYNHQDLPPSQFHLVKKPFAICYHPDSGPIFGAGADLLISSNCNSNMDSYSNLPHSYDGDGASPAVLMGDYNFTVADYEVFTPLGASGKHHKNERYQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01240993; iTF_00444301; iTF_01239309; iTF_01244240; iTF_00196465; iTF_00629923; iTF_00904233; iTF_00048750; iTF_00049398; iTF_00022298; iTF_00631611; iTF_00084029; iTF_00641699; iTF_00271493; iTF_00399688; iTF_00270090; iTF_00978538; iTF_01291959; iTF_01481061; iTF_01163334; iTF_01345132; iTF_01121863; iTF_00032182; iTF_00030360; iTF_00031245; iTF_01188422; iTF_00422823; iTF_00852999; iTF_01480280; iTF_00753149; iTF_00110729; iTF_01216098; iTF_01014794; iTF_00244427; iTF_00647352; iTF_01283563; iTF_00814541; iTF_00813857; iTF_00854177; iTF_00003907; iTF_00950051; iTF_00329796; iTF_01366469; iTF_00117222; iTF_01120998; iTF_00395627; iTF_00415275; iTF_00870731; iTF_00965323; iTF_00951084; iTF_01296652; iTF_01310733; iTF_00466543; iTF_01295343; iTF_01349807; iTF_01510927; iTF_00722256; iTF_01566385; iTF_00987282; iTF_00151827; iTF_00465108; iTF_01107732; iTF_01499028; iTF_01349013; iTF_00387414; iTF_01351926; iTF_00349399; iTF_01047575; iTF_01345847; iTF_00056761; iTF_00278329; iTF_00431577; iTF_00920793; iTF_01258233; iTF_01058554; iTF_01123898; iTF_00956443; iTF_00130684; iTF_00755932; iTF_01022364; iTF_00328381; iTF_00627389; iTF_00789501; iTF_00886621; iTF_00929725; iTF_00830558; iTF_01371550; iTF_01530430; iTF_00735967; iTF_00308160; iTF_01518208; iTF_00841989; iTF_01311692; iTF_00740175; iTF_00740176; iTF_00330871; iTF_00392888; iTF_00388896; iTF_00927918; iTF_00998961; iTF_00249108; iTF_00807760; iTF_01307383; iTF_00376461; iTF_01227474; iTF_01106522; iTF_01290557; iTF_00911231; iTF_00413688; iTF_00792346; iTF_00459110; iTF_00026231; iTF_00137150; iTF_01098640; iTF_00138261; iTF_00004799; iTF_01050505; iTF_00078752; iTF_00394688; iTF_01024224;
90% Identity
iTF_01481061; iTF_00415275; iTF_01283563; iTF_01480280; iTF_00753149; iTF_00852999; iTF_00422823; iTF_00399688; iTF_00244427; iTF_00870731; iTF_01345132; iTF_01121863; iTF_00814541; iTF_00813857; iTF_01366469; iTF_01296652; iTF_00722256; iTF_01566385; iTF_00987282; iTF_01227474; iTF_01022364; iTF_00929725; iTF_01290557; iTF_00841989; iTF_00110729; iTF_01014794; iTF_01311692; iTF_01310733; iTF_00755932; iTF_00886621; iTF_00078752; iTF_01345847; iTF_00641699; iTF_00647352;
80% Identity
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