Spec000963.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Schizotus pectinicornis
Gene Symbol
Hr39
Assembly
GCA_951805265.1
Location
OX638202.1:8817382-8829831[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.14 9e+02 -0.9 2.4 47 103 202 262 124 312 0.59
2 4 3.7e-08 0.00025 20.7 0.0 1 24 388 411 388 422 0.87
3 4 0.01 67 2.8 0.0 57 115 418 477 408 499 0.71
4 4 2.9e-73 1.9e-69 235.2 0.1 205 408 519 717 499 717 0.97

Sequence Information

Coding Sequence
ATGGCCGCAGACATGAGGTCTCCCAACGTGTCCGTAACACCCATTAACATGGAGCCCCCCTATCCGTCGACGGCGATTGCCAACTGCGACTTGCCGGGTGGGGAGCCCCAACGCACCAGGAGCGCCCCTCATCCTGGGCTGCTCACCAACGGAGACGTTCTAGACAGCTCTGATGCCGAAGTGGCCCAGATAGATTTTCAATGTGCCGTGAATATGAGGCACAAAACGAAAAGGGAGGGTGCCGACGTGCCCAGGCCAATGTCCTGGGAGGGAGAACTGTCGGATCACGAAAGGGATATGTGCGTCGACGATGATAGCGGATGTCAGGTACCCGAGAACCTATCCGTTTCACAACCCAAACTCAACTCGAGTGTGGGCTTGGACTCGAAGGAGAGCCCTATCCTGCGGCTGAAGCAGCCACCGATGGGCAACTATTCGCTGCACAGCACCCCCAGTAATTCGCCGTTGTTGAGCCAGCGCCACCCCGTAACCGGTGTACCCATCATCAGCCACAAAGACATAATGCACAAAGCCCTCAACGTACCACCGACGCCCAGTCCGGATTCCGCCATTCATTCGGCGTACAGTGTATTCAGTTCGCCAAATCAAAGCCCTTTAACACAAAGACATATCACGTTAACGCCGAATTTGAGCAGGAACAATAGTGATGCCTCACACTCGAGCTGTTGCAGTTATTCCAGTGTTTCGGTTTCGGTATCGCCTACGCAACAGTTCTCGCCCACTCACAGTCCTATCCAGgGCCGCCATATGCACAGTATTCACAGTAGTCCTTTACATCACAACGTTCTGTACCGTAGTCTGCAGGAGGATCCCAGCGTCCAGTACAGCGCTGAACACGATGGCCTCGACGAGGTCGAAGATAAGACTGGCTTAGTTCATACGTCCCTGCCTGCCCAACCAGGCATCTCCCGTCAACAACTCATCAACAGCCCTTGCCCCATCTGCGGTGATAAAATATCCGGCTTCCATTACGGCATCTTTAGTTGCGAATCCTGCAAGGGATTCTTCAAGCGCACAGTTCAAAACAGAAAAAACTACGTTTGTTTGCGGGGCGCCGCATGTCCAGTCACAGTCGCCACCCGAAAAAAGTGCCCAGCTTGCCGATTCGATAAGTGTTTACAATGCGGAATGAAATTAGAAGCCATCCGAGAAGATAGAACGAGAGGTGGTCGTTCCACTTACCAGTGTTCGTATTCGCTGCCACCTTCGTTGAGTAACCATGCTGAATTGAGGGCTAGTTCTACGGATTTAAGACAAAGTGTAGGAGATGCCCATCACGGGTTGACTGTTAAGTTAGAGCCTGCGGATTCCGCAATGTCGCATCATAAACGAAGCTCTATGCCAGGGTCGAAGGGTGTCCCAGCATTATTGCAAGAGATAATGGATGTGGAGCACCTGTGGCATTACAACGAAATGGAACTGAATAAACTAAGTACTGAAGGCCATTTAGGTAAGGAAGGAGCGAGCGGAGCCGTCCACAACCTCTCGAACCATCCCCTCCTAGCTGGCACTGCATTAGCAGGTTCGACTGATACTAATCCCGATTTCGTTGCAAACCTGTGCAATATAGCCGACCGTCGCCTAtacaaaatagtaaaatggTGCAAGAGTCTGCCTCTTTTCAAGAACATATCCattgacGACCAGATTTGTCTGCTTATCAATTCTTGGTGCGAGTTGCTTCTATTCTCGTGCTGCTTTCGATCCATGTCGACTCCGGGCGAAATCCGAGTGTCTCTCGGGAAAAGCATTACTTTGAACCAGGCCCGAGAAATGGGGATGCAAGCTTGCATTGAGAGGATGCTAAATTTCACGGACCAACTTCGAAGGTTGAAAGTCGACCAGTACGAATACGTAGCTATGAAAGTTATAGTTCTGCTCACTTCCGATACTTCCGAGTTGAGGGACGCCGAAAAAGTGAGGGCCTCTCAGGAGAAGGCGTTGAAAGCTTTGCAAGACTACACTTTGAGCCATTACCCAGACAGTCCTGCTAAATTTGGAGAGTTACTCCTCCGCATTCCTGAACTACAACGAACTTGCCAGGTTGGAAAAGAGATGTTGACTATAAAATCAAAGGAAGGGGACGGACCCAGCTTCAATCTTCTCATGGAGCTGCTCCGCGGAAATCACTAG
Protein Sequence
MAADMRSPNVSVTPINMEPPYPSTAIANCDLPGGEPQRTRSAPHPGLLTNGDVLDSSDAEVAQIDFQCAVNMRHKTKREGADVPRPMSWEGELSDHERDMCVDDDSGCQVPENLSVSQPKLNSSVGLDSKESPILRLKQPPMGNYSLHSTPSNSPLLSQRHPVTGVPIISHKDIMHKALNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHITLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHMHSIHSSPLHHNVLYRSLQEDPSVQYSAEHDGLDEVEDKTGLVHTSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLSNHAELRASSTDLRQSVGDAHHGLTVKLEPADSAMSHHKRSSMPGSKGVPALLQEIMDVEHLWHYNEMELNKLSTEGHLGKEGASGAVHNLSNHPLLAGTALAGSTDTNPDFVANLCNIADRRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLNQAREMGMQACIERMLNFTDQLRRLKVDQYEYVAMKVIVLLTSDTSELRDAEKVRASQEKALKALQDYTLSHYPDSPAKFGELLLRIPELQRTCQVGKEMLTIKSKEGDGPSFNLLMELLRGNH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00753059;
90% Identity
iTF_01283426;
80% Identity
iTF_01329839;