Basic Information

Insect: Scaptomyza reducta
Gene Symbol: zfh1
Assembly: GCA_035044485.1
Location: JAWNNV010001098.1:179482-184343[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.5e-05 0.0017 18.6 1.0 1 23 134 156 134 156 0.97

2 15 0.15 11 6.7 3.0 3 23 164 184 162 184 0.89

3 15 8.4e-05 0.0058 17.0 0.1 1 23 349 371 349 371 0.98

4 15 0.00029 0.02 15.3 0.9 1 23 377 399 377 399 0.98

5 15 3.2e-05 0.0022 18.3 2.2 1 23 430 453 430 453 0.95

6 15 0.012 0.85 10.2 3.1 1 23 480 502 480 502 0.94

7 15 0.017 1.1 9.8 1.3 1 23 508 531 508 531 0.97

8 15 0.025 1.7 9.2 0.4 3 19 540 556 539 557 0.95

9 15 0.00015 0.01 16.2 5.6 1 23 566 588 566 588 0.97

10 15 0.038 2.6 8.6 1.2 2 23 594 615 593 615 0.96

11 15 8.6e-06 0.00059 20.1 1.0 1 23 624 646 624 646 0.98

12 15 0.00097 0.067 13.6 0.1 3 23 654 674 652 674 0.97

13 15 5.2e-05 0.0036 17.6 0.5 1 23 680 702 680 703 0.95

14 15 0.021 1.5 9.4 0.5 1 23 713 735 713 735 0.97

15 15 0.00087 0.06 13.8 1.7 1 23 1212 1234 1212 1234 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.5e-05	0.0017	18.6	1.0	1	23	134	156	134	156	0.97
2	15	0.15	11	6.7	3.0	3	23	164	184	162	184	0.89
3	15	8.4e-05	0.0058	17.0	0.1	1	23	349	371	349	371	0.98
4	15	0.00029	0.02	15.3	0.9	1	23	377	399	377	399	0.98
5	15	3.2e-05	0.0022	18.3	2.2	1	23	430	453	430	453	0.95
6	15	0.012	0.85	10.2	3.1	1	23	480	502	480	502	0.94
7	15	0.017	1.1	9.8	1.3	1	23	508	531	508	531	0.97
8	15	0.025	1.7	9.2	0.4	3	19	540	556	539	557	0.95
9	15	0.00015	0.01	16.2	5.6	1	23	566	588	566	588	0.97
10	15	0.038	2.6	8.6	1.2	2	23	594	615	593	615	0.96
11	15	8.6e-06	0.00059	20.1	1.0	1	23	624	646	624	646	0.98
12	15	0.00097	0.067	13.6	0.1	3	23	654	674	652	674	0.97
13	15	5.2e-05	0.0036	17.6	0.5	1	23	680	702	680	703	0.95
14	15	0.021	1.5	9.4	0.5	1	23	713	735	713	735	0.97
15	15	0.00087	0.06	13.8	1.7	1	23	1212	1234	1212	1234	0.98

Sequence Information

Coding Sequence: ATGAACAACCAGGATTATGGCGGCATCCATTGGATACAGCAGGAAAGCAGCGCCGTCGACGTCACCGACAGCGAGGTGACGGCCGCCTATTTGGTGAACGGCAATGCCACCGACGAGGATCTCGACCATATGGCCGCCGAAAATCTCATCTTTATGCGCGACGGCCAACTCAGCGAGATCACTGGCGGCACTGTGTTGATCACAGACAGCGGCAACGTTGCCTATGCCGAGTCCTTTGACGACGATGCTCAGGTCGTCACCGAGGAGATCATCACCGATGACTGGGTGCAGCACCAAGGCGCCGAGCGcgTGGAAATTGCCGCGGAGCAGATAGCCGGCAATGGCAGCTCCCAGGAACTCCTGGACATGCAGCAGAACGAGTATATGGCCATGCGTCCCTATCCCTGTGACTTCTGCAGCCGGCGCTTTCGCAAAAAGGCCAGCCTCAACAATCATATGCTGGCCCACCAGAACGATCGGCCGCATCTCTGCAAGCTGTGCGGCGCGAGATTCTCGCGACGCGCCGAGCTCATCTGCCACTTCAAGGCGCATGCGGAGGCGCAGGCAGACGAAGAGGCAGCCGCCGCCGAAGCTGCTGCCATCAAATTcgagccacagcagcagcagcagctgaacgATGATCATCTGATCTACGAGCAGGAATGGCCGCTCTACCAGGAGCAGGAACAGGCACAGGAGCAGGAACATGAACAGGAGCGGGAGCAggaacaggagcaggagcaggagcaggagcggGAGCATGAACAGGAgcgggagcagcagcaggagcaggagcaggagcaggaggagcagcagcaactggccAGCTATGTGGCAGCACCAACAGCTGCCCGCGGACGCATCAGTCGCCTCAAGCTGAAGGAGGAGAGCACCCAATACATTGTGATGGCGGATAAGCAGCAGCCGGCGGAGTTCATGGACTGCGAGGAGTTGCACCAGCCGCTGGCCACACCCTCAATCCTCGAAGCAGCCGAAGGAGTACCAGATACTGTGCGCTATCCCGTGCTGGATCCCGGCAAACCCTTCGTCTGCCAGCAGTGCGGCCTGGCCTTTGCGCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGCGTGGACTCGCCGTTCGAGTGTAATCAGTGTCAGGAGATGTTCTGGGACAACTACAGTCTGCAGGAGCATCAGAAGACCCATCAGTTCGAGGAGAGCAATTCGGAATATGATCCCGCCTCCGGCGGCGAGGAGAGTGTCAGTGAATCGGAGCCGGATCAACTCTACGGCGACTTCTACTGCAGCGAATGCGGCATCTCGTTTCATCGCCAGGATCTGCTGCGGCGCCatgccaagcagcagcacagcAAGCTGCAGGGAAGTGGCAACCAGGTGGAGGAGGAGGTTGCAGGCGAGGGCGGCGACGTTGCCACAGATGCGCCACACTGTTGTCATACGTGCGGCAAGACATTTCCGAGCGTACTCAAGCTGCTGGCCCATGCGGAAATCCACAGACGTTTCCCGCCCTTCAAATGCGTCCTGTGCGGCGTTAGCTTCTATGAGGAGCAGGCAATTAAGCGGCATCTGCACACACGCCATCCCCACGAGCTGAAGCCCAACTCGTGTGTGCTCTGTGGCAAGGAGTGCCGCGACCGCAAGGCTCTCATCAAGCATGCCTGGGATCACTCGCGCGAGAAGTGCCACTCGTGCAGCAAGTGTGGCAAGAACTTCCACAACAAGGCGCGTCTGAAGCGGCACATGGCCTCGCATCGCGACAAGTCGGTGGTCTGCGAGGTCTGCCACGAGGAGTTCCCCGACGGACGCACCCTGTCGAATCATCGGCATTCGCATAGCACCACGTCGCCGGGCAAACTGTTCCCCTGCCACGAGTGTGGCAAGACCTTTGGTTCGCGCAGCTCGCAGCAGATCCATGTGCGCATTCACACGGGCGAACGTCCGTACGGCTGTCGCTACTGCTGGAAAGCCTTCGCCGATGGCGGCACTCTGCGCAAGCACGAGCGGATTCATACGGGCGAGAAGCCGTATGCCTGTTCGGTGTGTCCGCGTGCCTTCAATCAGCGCGTCGTGCTGCGCGAACACATACGCTCGCATCACTCGGGCCTCGATGCGGCACGTGGCACGTATCATTGCACGGTCTGCTCCGCGGATCTGTCCTCGTCCAATGACCTCATCAAGCATCTGATCCAACACAGCGACACGAACACGGCCAAACAGCGACAGCCAATTACTGGTCCCCGCAAGTATAAGCGTCGCAGGAAACTTCAACCGCATGAGATAGCGCACATGCGCGAACGTGAAGAGTATGCCAGTGATATGGAGTACTGCGATTTGGATGTGGAGAACGTTGACGATCTGCTGGATACGGCGGAACCACAGCCAGCCAAAAAGGAGAAGCGCAAGCGCAATACAGCCAGCAAAACAGTTAACCAGGAAGCTGCCAACTCGCCCAATAAGTCGGATCGTCTGTGGGATGAGAAGTTCATCCAGTCGAATGGAGGAACTGTGAATCCAATGCATAATGATGATATCTTTCACATTGATTCGCTGGTGGTTGTCAATGACACGGCGCTGCAGCCAGTGGGCACAGGCGATGTGGCAGCCACAAAGGCAAGGCGTGGCGGCAAGCAAACTGAAGAGTCCAGCAAAAAGTCGAGCAACAAAAGGaaagcagccacaacaacaactggagcagcaacaacaacaactggagcAGTTAGTTCTTCGCGTCCCCGCATGATACACACCGAAAAGTCGCGCGTGCCGCCAGAGAAAAAGTCGCGCAGTCGCAGCTATGTCACGCGCACCAATACCAACGAGCCGCAGAGCAGCTGCACCAGCCTGGTCAAGTCCAGTTCGCGTATTGTGGATGACTACGAGATTATATCACCTGCCACACAGCCACCGAATCAAATCAGTTCCAGTCCGCTGCACATCAAACAGGAGCaggaacaccaacaacaacaacaacagcacaaccAGCGGGTTCAGCTCATGTACGATGATACCCACTTGCTGATCGATGCGGGTCTGTTGCGGGAGAAGACCTACGAGAAGTTCAATCCCAGCATTGTTAATGATCTGGAGGAGATCTTGCGTAGTCCGCTCAAGCATGATCGTAATGCCCGACTGCGCTTCATCAGCGAATCCTCGACGACGCCACAATTTCTGCCCGAGGAGGAGCAGAATCTGATCAAGATTGAGCCCACGTCGCCGGATTTGCGCGAAATGGTGGAGAGTCAACAGCGCATAAGTGCCACAGGACACACAACTgcctcatcatcgtcatcgtcagcGCGTACTTCGTCACGGCATCTGCGACAGCTAACTGCCAATGGTTCGGAAAGGACGAGCACTAAACGCACTGCCAGCAAACAAGtgtccagctccagctccaagAAATCTACATCCACATCTTCCATCTCCGGCAGCAAAACCAATTCGTACCTCAGCAGCTATGGCGTCGACTCGTACCATGTACAGTGTGTGGCAAGCAGCACGAACTCGTCGGATGTCAGTTCCGGTTTCTTTTCCATCTCCGAGGTGGTATCCGCCGCGGATGCAGCCGATGCAGCGGCCAAAGCAGCTGCGGCCTGCAAAACGGAGCGACGGGCCCGTTGCTTTGAATGCGAAATGTGTTCGTGCAATTTTCCGGATCGTGCCCAGCTGCTGGAgcacatgcatatacacatCTAG
Protein Sequence: MNNQDYGGIHWIQQESSAVDVTDSEVTAAYLVNGNATDEDLDHMAAENLIFMRDGQLSEITGGTVLITDSGNVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELICHFKAHAEAQADEEAAAAEAAAIKFEPQQQQQLNDDHLIYEQEWPLYQEQEQAQEQEHEQEREQEQEQEQEQEREHEQEREQQQEQEQEQEEQQQLASYVAAPTAARGRISRLKLKEESTQYIVMADKQQPAEFMDCEELHQPLATPSILEAAEGVPDTVRYPVLDPGKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASGGEESVSESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHSKLQGSGNQVEEEVAGEGGDVATDAPHCCHTCGKTFPSVLKLLAHAEIHRRFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIKHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMREREEYASDMEYCDLDVENVDDLLDTAEPQPAKKEKRKRNTASKTVNQEAANSPNKSDRLWDEKFIQSNGGTVNPMHNDDIFHIDSLVVVNDTALQPVGTGDVAATKARRGGKQTEESSKKSSNKRKAATTTTGAATTTTGAVSSSRPRMIHTEKSRVPPEKKSRSRSYVTRTNTNEPQSSCTSLVKSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQQQQQHNQRVQLMYDDTHLLIDAGLLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFISESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRISATGHTTASSSSSSARTSSRHLRQLTANGSERTSTKRTASKQVSSSSSKKSTSTSSISGSKTNSYLSSYGVDSYHVQCVASSTNSSDVSSGFFSISEVVSAADAADAAAKAAAACKTERRARCFECEMCSCNFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01320605;
90% Identity: -
80% Identity: -