Basic Information

Insect: Scaptomyza reducta
Gene Symbol: Hr39
Assembly: GCA_035044485.1
Location: JAWNNV010001393.1:1420-5362[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.36 3.1e+03 -2.8 12.8 31 202 35 220 21 225 0.61

2 3 2 1.7e+04 -9.0 25.2 25 157 191 330 185 376 0.55

3 3 5e-99 4.3e-95 319.5 23.4 1 408 513 927 513 927 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.36	3.1e+03	-2.8	12.8	31	202	35	220	21	225	0.61
2	3	2	1.7e+04	-9.0	25.2	25	157	191	330	185	376	0.55
3	3	5e-99	4.3e-95	319.5	23.4	1	408	513	927	513	927	0.84

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAACAGTGTGTTTCACCGGGTGCCAGTGGCGTTGGCAGTTATCAGCTGCCCGTTAACATgtccacaacaacagcaacaacatcaacgccAACAAtcacagcgacaacaacatcgcagcaacaacagcagcagcaacaacaacgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGATGATCTGGCAACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAACTACAACAATCATACCAATCACAATAATCACAATCATACCAtggcaggaggaggaggcggcAGTCTGCGGATTCCCTTGGGCGTTGCCCACAATGAAGATGAATCCGATTCGGATGCCGAGCTGGCCAACATTGAGAATCTGAAGGTGCGTCGCAGGGCAGCCGACAAGAACGGACCACGTCCCATGTCCTGGGAGGGTGAGCTCAGCGAGAACGAGACGACGAACGGCGCTGCCGACGACGAGGAGCTCATGGAAACGGAGACGGTGATCAAGAGCGAGCACGTGAcgagcaccagcaacagcagcagcagtcagcagCAGGTGAATGCCATGTTGCAGCCGATCAAAACCGAACTGGAGCACATAGCCGGCgagatgcaacagcagcagcagcagcaacaacaacaacagcagctgcaacaacagctgcaacagcagcagcagcagcagcaacaacagcaattgcaactgcaacagctgcagcagccacaacaattgCTGCCGCTGAAGCACAAACTGAAGTTGGCGCCAACACAAAGTGATCCCATCAATCTAAAATATgaacccacaacaacaacaaccacaacaacaacatcgttACTCTGCGATCGCAGCAAATCCAACAGTGGCGGCCACTTGCCCCTGTTGCCCGCCAATCCAAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAGTCGCCGCTGACGTCCCGCCACGCCCCCTACACGCCCTCGCTGAGCAGGAACAACAGCGATGCCTCGCACAGCAGctgctacagctacagctccGAGTTCAGTCCCACCCACTCACCCATCCAGGCACGCCATGCCACCGGAGTGGCAGCCCTGTTTCCGGGCAATGCTGCAAATGGTGGTGGCAGTGCCAATGGTGCACTGCATCATCATAGTGTACTGTATCGGCCGCTGAATGTGGATGCGGCGGGTGCGCAGGAGGCACAAAATCTAAGCATGGATGCTGGTGGCGCTCTGGATGCGAGTGCCACATTGCCTGCCTCACCGGCTGGCATCTCGCGCCAGCAGTTGATCAACTCACCCTGTCCGATATGCGGCGACAAGATCAGCGGCTTCCACTATGGCATCTTCTCGTGCGAATCCTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAagaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGAAAGAAGTGCCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAGCTGGAGGCGATACGTGAGGATCGCACACGCGGCGGTCGCTCCACCTATCAATGCTCCTATACGCTGCCCAATTCGATGCTGAGTCCATTGCTTAGTCCGGAtcaggcagctgctgctgctgccgccgccgccgcagttgtcaatcagcagcagcaacaccaacaccaacaacaccagcaacaccagcaacatcaacaccaacaacagcaacatcaacaacaccagcagcagcagcaacatcagcgacttcagcagcaacatcagcaacagcaaacacatcAGCAACATGGTGCACTTAATGGCTTTGGTGGCGGCTCCAACTCGTTGCCAGCCAGCCCAAGTCTTGGCGGCGCATCCATCAAGACGGAACAAACGGATCAGCTCAATCATCATacaacatcattatcatcgtcGCGAGCCTTAAGCATTCCAGCTCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCAGAATTGGCGCGCATCAATCAACCGCTGTCCTCATTCGCATCCGGtggctcatcatcatcgtcgtcgtcgggtGCCGCGGGCGGTTCAAGTTCCGCCGGACAGCATACGGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCCGGTCTCTCATCGAATGGCGAGAACGCCAATCCCGATCTGATTGCACATCTCTGCAATGTGGCCGATCATCGTCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCCCTCTTCAAGAACATCTCGATTGACGATCAGATTTGCCTGCTCATCAATTCGTGGTGTGAATTGTTACTCTTCTCCTGCTGTTTTCGTTCCATTGATACGCCCGGCGAGATCAAGATGTCGCAGGGCCGAAAGATTACGCTCGCCCAGGCCAAGACCAATGGCTTACAGGCCTGCATTGAGCGCATGCTCAATCTGACGGATCATTTGCGACGACTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTCCTGCTGCAGTCAGACACCACGGAGCTGCACGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCATACACGTTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGTTGCTGCGCATACCCGATCTGCAGCGGACATGTCAGCTGGGCAAGGAAATGCTGACGATTAAAACGCGCGATGGTGcagatttcaatttgttgatgGAATTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQCVSPGASGVGSYQLPVNMSTTTATTSTPTITATTTSQQQQQQQQQRHNVSVTNIKCELDDLATPTNGNLVPVIANYNNHTNHNNHNHTMAGGGGGSLRIPLGVAHNEDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETTNGAADDEELMETETVIKSEHVTSTSNSSSSQQQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQLQQQLQQQQQQQQQQQLQLQQLQQPQQLLPLKHKLKLAPTQSDPINLKYEPTTTTTTTTTSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHATGVAALFPGNAANGGGSANGALHHHSVLYRPLNVDAAGAQEAQNLSMDAGGALDASATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAAVVNQQQQHQHQQHQQHQQHQHQQQQHQQHQQQQQHQRLQQQHQQQQTHQQHGALNGFGGGSNSLPASPSLGGASIKTEQTDQLNHHTTSLSSSRALSIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGSSSSSSSGAAGGSSSAGQHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_01320497;
80% Identity: iTF_01327216;