Basic Information

Insect: Scaptomyza polygonia
Gene Symbol: zfh1_2
Assembly: GCA_035044585.1
Location: JAWNNU010000906.1:3409157-3413333[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.7e-05 0.003 18.5 1.0 1 23 139 161 139 161 0.97

2 15 0.00079 0.086 13.9 0.8 3 23 169 189 167 189 0.91

3 15 9.1e-05 0.0099 16.9 0.1 1 23 360 382 360 382 0.98

4 15 0.00065 0.071 14.2 0.8 1 23 388 410 388 410 0.98

5 15 8.7e-06 0.00094 20.1 2.3 1 23 441 464 441 464 0.97

6 15 0.00075 0.081 14.0 0.4 1 23 507 529 507 529 0.94

7 15 0.018 1.9 9.7 1.3 1 23 535 558 535 558 0.97

8 15 0.027 2.9 9.1 0.4 3 19 567 583 566 584 0.95

9 15 0.00016 0.017 16.1 5.6 1 23 593 615 593 615 0.97

10 15 0.041 4.5 8.5 1.2 2 23 621 642 620 642 0.96

11 15 9.3e-06 0.001 20.0 1.0 1 23 651 673 651 673 0.98

12 15 0.0011 0.11 13.5 0.1 3 23 681 701 679 701 0.97

13 15 5.6e-05 0.0061 17.5 0.5 1 23 707 729 707 730 0.95

14 15 3.9 4.3e+02 2.3 0.3 1 23 740 762 740 762 0.89

15 15 0.00045 0.049 14.7 0.6 1 23 1288 1310 1288 1310 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.7e-05	0.003	18.5	1.0	1	23	139	161	139	161	0.97
2	15	0.00079	0.086	13.9	0.8	3	23	169	189	167	189	0.91
3	15	9.1e-05	0.0099	16.9	0.1	1	23	360	382	360	382	0.98
4	15	0.00065	0.071	14.2	0.8	1	23	388	410	388	410	0.98
5	15	8.7e-06	0.00094	20.1	2.3	1	23	441	464	441	464	0.97
6	15	0.00075	0.081	14.0	0.4	1	23	507	529	507	529	0.94
7	15	0.018	1.9	9.7	1.3	1	23	535	558	535	558	0.97
8	15	0.027	2.9	9.1	0.4	3	19	567	583	566	584	0.95
9	15	0.00016	0.017	16.1	5.6	1	23	593	615	593	615	0.97
10	15	0.041	4.5	8.5	1.2	2	23	621	642	620	642	0.96
11	15	9.3e-06	0.001	20.0	1.0	1	23	651	673	651	673	0.98
12	15	0.0011	0.11	13.5	0.1	3	23	681	701	679	701	0.97
13	15	5.6e-05	0.0061	17.5	0.5	1	23	707	729	707	730	0.95
14	15	3.9	4.3e+02	2.3	0.3	1	23	740	762	740	762	0.89
15	15	0.00045	0.049	14.7	0.6	1	23	1288	1310	1288	1310	0.98

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCAGCATCCACTGGATACAGCAGGAAAGCAACACCACCGACGACACCGACAGCGAGGTGACAGCCTCCTATTTAGTGAATGGGAATGCCACCGACGAGGATCTCGACCATATGGCAGCCGAAAACCTCATATTTATGCGCGACGGTCAACTTAGCGAGATCATTGCAGCAAACGAGGCTGGAGGCACTGTGTTGATCACAGACAGCGGCAATGTTGCCTATGCCGAATCGTTTGATGATGATGCTCAGGTTGTCACTGAAGAGATCATCACCGATGACTGGGTTCAGCACCAAGGAGCAGAGCGCGTGGAAATAGCTGAGGAGCAGATAGCTGGTAATGGTAGCTCACAGGAACTGTTGGATATGCAGCAGAATGAGTATATGGCCATGCGTCCATATCCCTGTGACTTTTGCAGCCGGCGTTTTCGCAAAAAGGCCAGTCTCAACAATCATATGCTGGCGCATCAAACCGATCGTCCGCATTTGTGTAAGCTTTGCGGAGCTCGTTTCTCGCGACGCGTCGAGCTAATCCGTCACTTCGAGGCCCATGCCCTAGCGCAGGAAGCAGATGAGGTTGCCGCCGCAGCTGCCAAAGCTGCTGTAGTGAAATTcgagccacagcagcagcacgagCAACAGCGACAAATTGATGATAATTTATACGAACAGGAATGGCCGCTGTATAATGAACAAGAACAGGAACAGCACGAACAGGACCAGCCACACCAACTGGAGCAGCATGAGCAGGAGCATCTGATCCAAGAGGCCAGCTATGCGACAGTTAGCGCTGTTGCAGCGCCAACAGCTGCTCGTGGTCGCATTAGTCGCCTCAAACTCAAGGAGGAAAGCAGCACCCAGTATATTGTGATCGCtgataagcagcagcaggctgCCGACAATGAGCTGCGTCAATATATGGATTGCGAGGAGCTTAACCAACAACCGCTTTCTACAAACATCACATCGAATGATGCAACACACTCAATCCATGCTGGCCAGGTAGCTTCGGATGGGGCACAACAAACTTTACGCTATCCTGTGGTGGACGAATGCAAACCATTTGTGTGCCAACAGTGCGGTTTGGCATTTGCACGCGAAAAAGCTCTCGTCTCTCACATCAAGAATCATCGCGTCAACTCACCATTCGAATGCAATCAGTGTCAAGAGATGTTCTGGGATAATAACAGCTTGCAGGATCATCAAAAAACGCATCAGTTCGAGGAAAGCAACTCGGAATATGATCCCGCATCTGCTGGCGAAGAAAGTGTTAGCGAATCGGAGCAAGATCAGCTATATGGTGATTTTTATTGCAGTGAATGCGGCATTTCCTTTCACCGCCAGGATCTGCTGCGTCGCCATGCCAAAAcgcaacacaacaaacaactagCAACTGCCACGCTTAACTCAACGGATGTAGAGGTAGAAGCCAACGGCAATGGCGATGGCGATGACAATGCCAAACTTGTAGCTCATAGTGTTGAAAATGCTAAAGATGTAGAACACAATTGTAATACGTGCGGCAAGTCATTTCCGAATGAATTGAAACTGCTTGCGCATGCTGAAATCCATAAACGTTTCCCGCCATTCAAATGCGTCCTGTGCGGCGTTAGCTTCTATGAGGAGCAGGCAATCAAACGCCATTTGCACACACGCCATCCGCACGAGCTGAAACAAAACTCATGCGTGCTGTGCGGCAAGGAATGTCGTGATCGAAAGGCTCTGATCAAGCATGCGTGGGATCATTCGCGCGAAAAGTGTCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCTCGGCTGAAGCGGCACATGGCTTCACATCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTTCCCGATGGTCGCACCTTATCTAATCATCGGCATTCACACAGCACAACATCGCCCGGCAAATTGTTTCCCTGTCACGAGTGTGGCAAGACCTTTGGATCGCGCAGCTCACAGCAGATTCATGTGCGCATTCATACGGGCGAACGTCCATATGGTTGTCGCTATTGCTGGAAGGCTTTTGCCGACGGTGGCACATTGCGCAAGCACGAGAGGATTCATACCGGCGAGAAACCCTATGCCTGCTCTGTCTGCCCGCGTGCCTTTAATCAGCGAGTTGTGTTACGAGAACATATACGATCGCACCACTCGGGTCTGGACGCTGCACGTGGCACGTATCATTGCATTGTCTGCTCGGCAGATTTATCCTCATCCAATGACCTTATCCAGCATCTTATTCAACACAGCGATACAAACACCGCAAAACAACGACAACCAGTTACTGGTCCCCGCAAGTATAAGCGTCGAAGGAAATTGCAACCGCATGAGATTGCACACATGCGCGAACGTGAGGAATATACCAGTGATATGGAGTATTGCGATTTGGATGTGGAGAATGTCGATGATCTGTTGGAAAGTTCAGAGCCATTGCCAGTTAAAAAAGAGAAGCGTAAACGCAATGCTGTCAGTAAAACAGTTAATCAAAGCAATGGCACGGAAACTCACTCCAACtcacaaaataaatcaaatgccAATAGCAATTCGGATCGTTTGTGGGATGAGAAATTCATGCAATCAAATACGAATGGCAATGGAAATCAAATGAACAATGATGATGCCTACAAAGGTATCTTTCACGTGGATTCGTTGGTGGCTATGAGTAATACGGCACTGCAGCCAGAAAGTGTTGCTACTAAGTCACGACGTGGTGGCAAACAAAACCCGACGCAGGCTGATGAGTCAAGCAAACTGGGACATGTTTCAAGCAGTCGCAATAGCAAAAGGAAAACTGGCAAAGcagccacaacagcaacaacagcagcagcagcagcagcagcagcaattttaGCAACAGCAGTCGGTTCTCGTCCCCGCATGATACACACAGAGAAGACTCGTTTGCCGCCAGAGAATGCCACCGCAAAGAAGTCGCGGGCAAGTCGCAGTTATATCACACGGACCCATGCCAACGAACAGCAGgcaagcagctgcagcaacagcagcagcagcctggTCAAGACTAGTTCGCGTATTGTAGATGACTACGAGATTATATCACCTGCCACACAGCCACCCAATCAAATAAGTTCCAGTCCGTTGCACATaaagcaggagcaggagcacCAGCAACACCAGCGCGTACAGCTAATGTATGATGATACACATTTGCTAATCGATGCGGGACTTTTGCGCGAAAAGACCTACGAGAAGTTTAATCCAAGCATTGTCAATGATTTGGAGGAGATACTGCGCAGTCCACTCAAGCATGATCGTAATGCACGTTTACGTTTCATCAGCGAATCATCAACGACGCCTCAATTTCTACCCGAAGAGGAGCAGAACCTGATTAAGATTGAGCCAACGTCACCGGATCTGCGTGAAATGGTTGAGAGCCAGCAGCGTGTGAATGCCACAGGACACACAACTGAAACAGCATTGTtatcctcatcatcatcatcatcagcgcGCACCTCATCACGCCACCTGCGACAGCTAACTGCCAATGGATCTGAAATCGGATCCACCACTTCAAGATCGGGCACTAAACGCAGCGCCAGCAAACAAGTCTCAAGTCAAGCAACCAGCTCCAAAAAATCCACATCAACATCATCTATCTCCGttagcaacagcaaaaacaactcGTACCTCAGCAGCTATGGCGTGGACTCGTACAACGTACAATGTGTGTCGGCCAGCGCAAACTCTTCGGACGTCAGTTCTGGTTTCTTTTCCATATCCGAGGTGGTGTCCGCTGCTGATGCCGCCGATGCAGCAGCCAAGGCAGCAGAGGCCAAGAAAACTGATCGTCGAGCTCGTTGCTTTGAGTGTGAAATGTGCTCGTTCAATTTTCCCGATCGCGCCCAGCTGCTGgaacatatgcatatacacaTCTAG
Protein Sequence: MNNQDYGSIHWIQQESNTTDDTDSEVTASYLVNGNATDEDLDHMAAENLIFMRDGQLSEIIAANEAGGTVLITDSGNVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAEEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQTDRPHLCKLCGARFSRRVELIRHFEAHALAQEADEVAAAAAKAAVVKFEPQQQHEQQRQIDDNLYEQEWPLYNEQEQEQHEQDQPHQLEQHEQEHLIQEASYATVSAVAAPTAARGRISRLKLKEESSTQYIVIADKQQQAADNELRQYMDCEELNQQPLSTNITSNDATHSIHAGQVASDGAQQTLRYPVVDECKPFVCQQCGLAFAREKALVSHIKNHRVNSPFECNQCQEMFWDNNSLQDHQKTHQFEESNSEYDPASAGEESVSESEQDQLYGDFYCSECGISFHRQDLLRRHAKTQHNKQLATATLNSTDVEVEANGNGDGDDNAKLVAHSVENAKDVEHNCNTCGKSFPNELKLLAHAEIHKRFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKQNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCIVCSADLSSSNDLIQHLIQHSDTNTAKQRQPVTGPRKYKRRRKLQPHEIAHMREREEYTSDMEYCDLDVENVDDLLESSEPLPVKKEKRKRNAVSKTVNQSNGTETHSNSQNKSNANSNSDRLWDEKFMQSNTNGNGNQMNNDDAYKGIFHVDSLVAMSNTALQPESVATKSRRGGKQNPTQADESSKLGHVSSSRNSKRKTGKAATTATTAAAAAAAAILATAVGSRPRMIHTEKTRLPPENATAKKSRASRSYITRTHANEQQASSCSNSSSSLVKTSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHQRVQLMYDDTHLLIDAGLLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFISESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVNATGHTTETALLSSSSSSSARTSSRHLRQLTANGSEIGSTTSRSGTKRSASKQVSSQATSSKKSTSTSSISVSNSKNNSYLSSYGVDSYNVQCVSASANSSDVSSGFFSISEVVSAADAADAAAKAAEAKKTDRRARCFECEMCSFNFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01320605;
90% Identity: -
80% Identity: -