Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.042 1.8e+02 2.3 0.7 23 48 8 32 5 38 0.81

2 6 0.0064 28 4.9 0.0 26 45 44 63 39 67 0.89

3 6 0.0064 28 4.9 0.1 26 46 127 147 119 152 0.87

4 6 6e-05 0.26 11.4 0.1 26 45 160 179 157 186 0.84

5 6 0.31 1.4e+03 -0.5 0.0 26 43 231 248 222 254 0.73

6 6 0.00029 1.2 9.2 0.1 27 52 265 290 262 292 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.042	1.8e+02	2.3	0.7	23	48	8	32	5	38	0.81
2	6	0.0064	28	4.9	0.0	26	45	44	63	39	67	0.89
3	6	0.0064	28	4.9	0.1	26	46	127	147	119	152	0.87
4	6	6e-05	0.26	11.4	0.1	26	45	160	179	157	186	0.84
5	6	0.31	1.4e+03	-0.5	0.0	26	43	231	248	222	254	0.73
6	6	0.00029	1.2	9.2	0.1	27	52	265	290	262	292	0.84

Coding Sequence: ATGCTGGACAACGCTAACGGTAGACCATTCAGATGTGACCAATGCAACTACACATCAAATCGTTCCTATGACCTACGGCGTCACCAGCAGCGTCACACCCGTAAGAAGCTCATCGAAGGCCATTCTCATAATTGCACTAAGTGTGAATTTGTTACCAAGTGGAAACGTAACATGAAACGCCACATGCAAAAACATGATAATGAGGAAGCCGCCTCAGAAGACGAACAAATAATTGAAGAGTATATAGTGGAGGTGCTTGAGAACTCTGAAACAGAACCCGACAATTATGAGCTAAGAACTGAAGCAGAATTCATCACAGATTCGGAAACAGATCAAACTAACAACGaagtagaaaaagaaaagggtCCACGGATTTTTAAGTGTGACCTCTGCCGCTATACAACCAAACGGTCCTTCGATCTGCGACGTCACATGCAGACGCATTATAAAGTTAAGATCGTTGATGGCGGAGCTCATAAATGCCCAAAATGCTCATTCGTAACAAAATGGAAACGTAATATTAGAAGACACATGCGAAAACACGAAAAAGACCCTGGTGAGGAAGTGGATGCGGTACAAATAGATGAGCAGTCGACTATTGAGTATAAAGTGGAGCTAATGGACTCAGAcaaagtgtatatgtatagtttTTCTAAGGCACTAGACAGCCAAAGTGTtgacaaaatttacaaatgcaCGCTCTGCGATTATGAAACTAAACGCATGTTTGACTTGCGACGTCATTCACTAAAACACGACAAGGAGAAGGCAATTTTAGGAATAGCCTATCAATGTAACGATTGTTCGTTCCTAACTAAATGGAAACGCAATATACAACGCCACATAGAGCAAAGGCACAAGAAAACTCCAGCTGCGGGCGAAGCGACGGATGAAGAattgttttataaaatttttgttgagCAAACATCCGAAACGGATGCGGACTCGTTTGAAGAAGAAATTGATACCTTAGAACTGAACGAGGAGAAAGATCCCGAGGTATTGCCTAGTCTATGGATTACCCTACCGTCAGAAGAGGCGTAG
Protein Sequence: MLDNANGRPFRCDQCNYTSNRSYDLRRHQQRHTRKKLIEGHSHNCTKCEFVTKWKRNMKRHMQKHDNEEAASEDEQIIEEYIVEVLENSETEPDNYELRTEAEFITDSETDQTNNEVEKEKGPRIFKCDLCRYTTKRSFDLRRHMQTHYKVKIVDGGAHKCPKCSFVTKWKRNIRRHMRKHEKDPGEEVDAVQIDEQSTIEYKVELMDSDKVYMYSFSKALDSQSVDKIYKCTLCDYETKRMFDLRRHSLKHDKEKAILGIAYQCNDCSFLTKWKRNIQRHIEQRHKKTPAAGEATDEELFYKIFVEQTSETDADSFEEEIDTLELNEEKDPEVLPSLWITLPSEEA

Sequence clustering based on sequence similarity using MMseqs2