Basic Information

Insect: Scaptomyza flava
Gene Symbol: Hr39
Assembly: GCA_003952975.1
Location: RKRM01000331.1:93324-119807[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.54 4.4e+03 -3.4 4.6 32 90 51 88 7 208 0.49

2 3 2 1.6e+04 -9.4 21.8 40 155 207 339 185 361 0.40

3 3 9.7e-101 7.9e-97 325.1 13.8 1 408 498 892 498 892 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.54	4.4e+03	-3.4	4.6	32	90	51	88	7	208	0.49
2	3	2	1.6e+04	-9.4	21.8	40	155	207	339	185	361	0.40
3	3	9.7e-101	7.9e-97	325.1	13.8	1	408	498	892	498	892	0.88

Sequence Information

Coding Sequence: atgccaaatatGTCGTGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTAGTGGCAGCTACCAGCTGCCTGTTAACATgtccacaacaacagcaacaccaacgacaacaacaaccgtGACACCAATatctcaacagcaacagcaacgtcaCAATGTCTCCGTGACGAATATTAAATGTGAACTGGATGAGCTGGCAACGCCAACAAATGGAAATTTGGTGCCAGTCATAGCCAACTATAACAATCATCAAAATCacaataatcataatcatagCGTAGGTGTAGGAGTAGGAGGAGGCGGAGGAGGCAGCCTGCGCATACCGCTAGGCGGTGGCCATAATGAGGATGAATCCGATTCGGATGCCGAGTTGGCAAACATTGAGAATCTAAAGGTGCGTAGACGGGCGGCCGACAAGAATGGACCACGACCCATGTCGTGGGAGGGTGAGCTTAGCGAGAACGAAACGAATGGCTGCGCCCACGACGAGGAGGAGCTCATGGAAACAGAGACGGTAATCAAGAGTGAGGTgaccaccaccagcagcagccacagccacagcagcagcagtcaggTGAATGCCATGTTGCAACCAATTAAAACCGAACTCGAGCATATTGCCGGTgagatgcaacaacaacaacaacagcagcagcatcagcagcaacaacaacaattgcaacaacatcagcagtcacaacaacaattgctgccACTCAAGCACAAGCTGAAACTGGCGCCAACACAAAGTGATCCCATCAACTTGAAATATGAGCccacaacaacgacgacaacaacaacatcgttACTCTGCGATCGTAGCAAATCCAATAGCGGTGGCCATTTACCGCTTTTACCCGCCAATCCAAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCACGGCACGCCCCCTACACGCCTTCGTTGAGTAGAAATAACAGCGATGCCTCGCATAGTAGCTGTTATAGCTATAGCTCCGAATTCAGTCCCACCCACTCACCCATACAGGCACGCCATGCCCCGCCAGCGGGTGTTGCAGCACTGTTTCCGGGCAATGCTGCAAATGGTGGCGCTGCCAATGGTGGACTGCATCATCATAGTGTACTGTATCGACCGCTCAATGTGGATGCAGTGGGTGCACAGGAGGCACAGAATCTAAGCATGGATGCTGGTGGCGCTTTGGATGCAAGTGCCACATTGCCTGCCTCACCGGCGGGCATCTCCCGCCAGCAATTGATCAACTCACCCTGTCCAATATGCGGCGATAAGATCAGTGGCTTCCATTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGATTCTTCAAGCGCACCGTCCAGAATCGCAAGAactatgtttgtgtgcgtggCGGACCCTGCCAAGTAAGCATCTCGACGAGAAAGAAGTGTCCTGCCTGTCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAGGCGATACGTGAGGATCGCACTCGAGGCGGTCGCTCCACCTATCAATGCTCCTATACGCTGCCCAATTCGATGCTTAGTCCATTGCTTAGTCCGGatcaggcagcagcagctgctgcagctgccgcaGCAGTTGtcaatcaacagcagcagcagcaacatcaacagcaccagcaacagcaacatcagcaacatcagcgacttcagcaacagcaacaagcacaTCAGCAACATGGTGCACCAAATGGCTTTGGTGGTGGCTCTAACTCGCTGCCATCCAGTCCAAGTCTTGGCGGAGCATCCATCAAGACGGAGCTAACTGAGCAGCTAAATCATCATgcaacatcattatcatcgTCGCGAGCATCAAGCATTCCAGCCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAGTTGGCGCGCATCAATCAACCGCTGTCTTCATTTGCGTCTGGTGGCACATCATCGTCGGGCGCCGCGGGCGGTTCAAGTTCCGCCGGACAGCACACTGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCGGGTCTCTCATCCAATGGTGAGAATGCCAATCCCGATCTTATAGCACATCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATTTCGATTGACGATCAGATTTGCCTGCTTATCAATTCGTGGTGTGAACTGTTACTCTTTTCCTGCTGTTTTCGTTCCATTGATACGCCCGGTGAGATTAAGATGTCACAGGGTAGAAAAATTACGCTGGCACAGGCTAAGACCAATGGCTTACAGGCCTGCATTGAGCGCATGTTGAATTTGACGGATCATTTGCGTCGTCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGTTGCAGTCAGACACCACGGAGCTGCATGAGGCGGTCAAGGTGCGCGAGTGTCAGGAGAAGGCGCTGCAGGGTTTGCAGGCATATACGCTGGCTCATTATCCCGATACGCcgtccaaatttggtgagcttCTACTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGCCAAAGAAATGCTGACGATCAAAACGCGCGATGGTGCAGATTTCAATTTGCTGATGGAATTGTTGCGCGGAGAACATTGA
Protein Sequence: MPNMSCIKTEQSVSPGASSGSYQLPVNMSTTTATPTTTTTVTPISQQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHQNHNNHNHSVGVGVGGGGGGSLRIPLGGGHNEDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGCAHDEEELMETETVIKSEVTTTSSSHSHSSSSQVNAMLQPIKTELEHIAGEMQQQQQQQQHQQQQQQLQQHQQSQQQLLPLKHKLKLAPTQSDPINLKYEPTTTTTTTTSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFPGNAANGGAANGGLHHHSVLYRPLNVDAVGAQEAQNLSMDAGGALDASATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAAVVNQQQQQQHQQHQQQQHQQHQRLQQQQQAHQQHGAPNGFGGGSNSLPSSPSLGGASIKTELTEQLNHHATSLSSSRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGTSSSGAAGGSSSAGQHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLAKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_01320497;
80% Identity: iTF_01321979;