Basic Information

Insect: Scaptomyza cyrtandrae
Gene Symbol: zfh1
Assembly: GCA_035044605.1
Location: JAWNNS010000640.1:121752-125874[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.7e-05 0.002 18.5 1.0 1 23 139 161 139 161 0.97

2 15 0.17 12 6.6 3.0 3 23 169 189 167 189 0.89

3 15 9.1e-05 0.0067 16.9 0.1 1 23 357 379 357 379 0.98

4 15 0.00031 0.023 15.2 0.9 1 23 385 407 385 407 0.98

5 15 3.4e-05 0.0025 18.2 2.2 1 23 438 461 438 461 0.95

6 15 0.011 0.81 10.3 3.0 1 23 502 524 502 524 0.94

7 15 0.018 1.3 9.7 1.3 1 23 530 553 530 553 0.97

8 15 0.027 2 9.1 0.4 3 19 562 578 561 579 0.95

9 15 0.00016 0.012 16.1 5.6 1 23 588 610 588 610 0.97

10 15 0.041 3 8.5 1.2 2 23 616 637 615 637 0.96

11 15 9.2e-06 0.00068 20.0 1.0 1 23 646 668 646 668 0.98

12 15 0.001 0.078 13.6 0.1 3 23 676 696 674 696 0.97

13 15 5.6e-05 0.0042 17.6 0.5 1 23 702 724 702 725 0.95

14 15 0.023 1.7 9.3 0.5 1 23 735 757 735 757 0.97

15 15 0.00017 0.012 16.1 0.5 1 23 1272 1294 1272 1294 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.7e-05	0.002	18.5	1.0	1	23	139	161	139	161	0.97
2	15	0.17	12	6.6	3.0	3	23	169	189	167	189	0.89
3	15	9.1e-05	0.0067	16.9	0.1	1	23	357	379	357	379	0.98
4	15	0.00031	0.023	15.2	0.9	1	23	385	407	385	407	0.98
5	15	3.4e-05	0.0025	18.2	2.2	1	23	438	461	438	461	0.95
6	15	0.011	0.81	10.3	3.0	1	23	502	524	502	524	0.94
7	15	0.018	1.3	9.7	1.3	1	23	530	553	530	553	0.97
8	15	0.027	2	9.1	0.4	3	19	562	578	561	579	0.95
9	15	0.00016	0.012	16.1	5.6	1	23	588	610	588	610	0.97
10	15	0.041	3	8.5	1.2	2	23	616	637	615	637	0.96
11	15	9.2e-06	0.00068	20.0	1.0	1	23	646	668	646	668	0.98
12	15	0.001	0.078	13.6	0.1	3	23	676	696	674	696	0.97
13	15	5.6e-05	0.0042	17.6	0.5	1	23	702	724	702	725	0.95
14	15	0.023	1.7	9.3	0.5	1	23	735	757	735	757	0.97
15	15	0.00017	0.012	16.1	0.5	1	23	1272	1294	1272	1294	0.98

Sequence Information

Coding Sequence: ATGAACAACCAGGATTATGGCGGCATCCATTGGATACAGCAGGAAAGCAGCGCCGCCGACGACACCGACAGCGAGGTGACTGCCGCCTATTTAGTGAACGGTAATGCCACCGATGAGGATCTCGACCATATAGCAGCCGAAAACCTCATCTTTATGCGCGACGGTCAACTTAGCGAGATCATCGCAGCGAATGAGGCTGGAGGCACTGTGTTGATCACAGACACCGGCAACGTTGCCTATGCCGAAtcttttgatgatgatgctcaGGTTGTCACTGAAGAAATCATCACTGATGACTGGGTGCAGCACCAAGGGGCGGAGCGCGTGGAAATTGCGGCGGAGCAGATAGCTAGCAATGGCAGTTCTCAGGAACTGTTGGATATGCAGCAGAATGAGTACATGGCCATGCGGCCGTACCCGTGTGACTTTTGTAGCCGGCGCTTTCGCAAGAAGGCCAGTCTCAATAATCATATGCTGGCACATCAGAACGATCGTCCGCATCTGTGCAAGCTGTGCGGAGCGCGTTTCTCGCGACGAGCCGAGCTAATATGTCACTTTAAGGCGCATGCCGAGGCTCAGGCAGATGAAGaggctgccgctgctgccgcgGAAGCTGCTGCAATAAAATTCGAGCCACAGCATCAGCAACTACAGCGACAGATCGATGATCATCTGATCTACGAACAGGAATGGCCGCTATACCATGACCAAGATCAAGAACAAGCACAGGAGCGCGAACAGGAGCAGCAAGAGCATGATCAGGAGAAACTGGTCCAACAGACCACCCAAGCAGCAGCCAGCGCTGTGGAACCACCAACAGCTGCCCGTGGTCGCATTAGTCGCCTCAAGCTTAAAGAGGAAAGCACCCAATACATTGTGATTGCTGATAAGCAACAGACGGCCGACAATGCCGAATTGCGACAGTTTATAGATTGCGAGGAGCTTAACCAACCGCTTGCTTCAAACACCACATCAAACAATGCAACACACTCAATCCTCGACAGCCAGCAATCATCCGAAGGGGCACACGAAACTTTACGCTATCCTGTGCTGGACCCAAGCAAACCATTCGTCTGCCAACAGTGCGGATTGGCATTTGCGCGCGAAAAAGCTCTCGTCTCCCACATCAAGAATCATCGCGTGGACTCCCCGTTTGAATGCAATCAGTGTCAAGAGATGTTCTGGGACAATTATAGCCTGCAAGAGCATCAGAAGACTCATCAATTTGAGGAGAGCAATTCGGAATATGATCCCGCATCAGGTGGCGAGGAAAGTGTTAGTGAATCGGAGCCAGATCAGCTATACGGTGACTTTTATTGCAGTGAGTGCGGCATCTCTTTTCACCGGCAAGATCTGCTGCGTCGCcatgccaagcagcagcatagCAAGCTGCAGGCAACTGGAAATATTGTTGCAACTGCCACAGATGCAGACGGTGGAGGCGACGGCGGTAACGGTGGCGTCGGAGTCGAAACTGACGGTGAAAATGCCAAAGATGCGCCCCACTGTTGTCATACGTGCGGCAAGTCATTTCCGAGCGTGCTGAAACTGCTTGCCCATGCGGAAATTCATAGACGTTTCCCGCCATTCAAATGCGTCCTGTGCGGCGTTAGCTTTTATGAGGAGCAGGCAATTAAACGCCATCTGCATACACGCCATCCGCACGAGCTGAAGCCCAATTCGTGCGTGCTGTGTGGAAAGGAGTGTCGCGATCGAAAGGCTCTAATCAAGCATGCCTGGGATCACTCGCGCGAAAAGTGTCACTCGTGCTCCAAGTGCGGCAAGAACTTCCATAACAAGGCTCGACTGAAGCGGCACATGGCCTCACACCGCGACAAGTCGGTTGTGTGCGAGGTGTGCCACGAGGAGTTTCCCGATGGTCGCACGTTATCTAATCATCGGCATTCGCACAGCACAACGTCGCCGGGTAAACTGTTCCCTTGCCACGAGTGTGGCAAGACCTTTGGTTCGCGCAGCTCACAGCAAATTCATGTGCGCATTCATACGGGCGAACGTCCATATGGTTGTCGCTATTGCTGGAAAGCCTTCGCCGATGGTGGCACATTGCGCAAGCATGAGCGGATTCACACTGGCGAAAAACCTTATGCCTGCTCTGTTTGTCCGCGCGCATTTAATCAGCGTGTCGTGCTGCGCGAACACATAAGATCGCATCACTCGGGTCTAGATGCAACACGTGGCACGTATCATTGCACTGTCTGCTCCGCAGATTTATCTTCATCCAATGACCTCATTAAGCATCTTATCCAACACAGCGATACAAACACGGCAAAACAACGACAGCCAATTaCTGGACCCCGCAAGTACAAGCGTCGAAGAAAACTGCAACCGCATGAGATTGCGCACATGCGTGAACGTGAAGAGTATGCTAGTGATATGGAGTTCTGCGATTTGGATGTGGAGAATGTTGACGATTTGCTGGATACTGCGGAACCATTGCCAGCCAAAAAGGAGAAGCGCAAACGCAATGCTGCCAGTAAAACAGTAAACCAGAGCAACGGCACGGAAGCTTCCAACTCGCCCAATAAGTCAAATTCGGATCGTTTGTGGGATGAGAAATTCATGCAGTCAAATGGTGGCAATGGGAATCAATTGAATAATGATGATGCATACAAAAGTATCTTTCACATTGATTCGCTGGTAGTTGTGAATGATACGGCACTGCAACCAGTGAGTTCAGCCGACGTTGCAGGCAGTACCACAAAGTCAAGGCGTGGCGGCAAGCAAACACAATCGCAAACCGATGAGTCAAGCAAATTGGGAAGTGTTGCAAGCAGtcgcaacagcaataaaaagaaatcagctaaagcagccaaagcagcaaTAACAGGAGTAGCAGCCGGCGCAGCAGGTAATACTTCTCGTCCCCGCATGATACACACAGAAAAGTCTTGTGTGCCGCAAGAAAATGCCACGTCAAAGAAGTCGCGCGGTCGCAGTTATATCACGCGCACCAATACGAACGAACACCAGAGCAGCTGCACTAGCAGCAGCCTGGTCAAGTCAAGTTCGCGTATTGTGGATGACTACGAGATTATATCACCTGCCACACAGCCACCCAATCAAATCAGTTCCAGTCCGCTGCATATCAAACAGGAGCAggaacaccaacaacaccagcgCGTCCAGCTCATGTATGATGATACACATTTGCTGATTGATGCGGCGCTGTTGCGTGAAAAGACGTACGAGAAGTTCAACCCGAGCATTGTTAATGATTTGGAAGAGATTTTGCGTAGTCCGCTCAAGCACGATCGTAATGCGCGACTGCGCTTCATCAGCGAATCATCGACGACACCACAATTCCTGCCCGAGGAGGAGCAGAATCTGATTAAGATTGAGCCAACGTCGCCAGATTTGCGCGAAATGGTGGAGGGTCAACAGCGTGTAACTTCAACAGGACACACTACTGCCACatcattgtcatcatcatcatcatcagcgcGTACTTCGTCACGCCACCTGCGACAGCTTACTGCCAATGGATCTGAAACTGGGTGCGGTTCAAGGGCGGGCACTAAACGCAGCGGCAGCAAACAAATGTCCAGTGCAACCAGCTCCAAGAAATCCACATCAACATCTTCCATTTCCggtagcaatagcaacagcaaaaccaaTTCGTACCTCAGCAGTTATGGCGTGGACTCGTACAATGTACAGTGTGTGGCGACCAGTACTAACTCTTCGGATGTGAGTTCCGGTTTCTTTTCCATCTCCGAGGTGGTATCTGCTGCGGATGCCGatgcagcagccaaagcagcagcagcctgcAAAACGGAGCGCCGGGCACGTTGCTTTGAATGTGAAATGTGTTCCTACAATTTTCCCGATCGTGCGCAGCTACTGgaacacatgcacatacacatctGA
Protein Sequence: MNNQDYGGIHWIQQESSAADDTDSEVTAAYLVNGNATDEDLDHIAAENLIFMRDGQLSEIIAANEAGGTVLITDTGNVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIASNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELICHFKAHAEAQADEEAAAAAAEAAAIKFEPQHQQLQRQIDDHLIYEQEWPLYHDQDQEQAQEREQEQQEHDQEKLVQQTTQAAASAVEPPTAARGRISRLKLKEESTQYIVIADKQQTADNAELRQFIDCEELNQPLASNTTSNNATHSILDSQQSSEGAHETLRYPVLDPSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASGGEESVSESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHSKLQATGNIVATATDADGGGDGGNGGVGVETDGENAKDAPHCCHTCGKSFPSVLKLLAHAEIHRRFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDATRGTYHCTVCSADLSSSNDLIKHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMREREEYASDMEFCDLDVENVDDLLDTAEPLPAKKEKRKRNAASKTVNQSNGTEASNSPNKSNSDRLWDEKFMQSNGGNGNQLNNDDAYKSIFHIDSLVVVNDTALQPVSSADVAGSTTKSRRGGKQTQSQTDESSKLGSVASSRNSNKKKSAKAAKAAITGVAAGAAGNTSRPRMIHTEKSCVPQENATSKKSRGRSYITRTNTNEHQSSCTSSSLVKSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHQRVQLMYDDTHLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFISESSTTPQFLPEEEQNLIKIEPTSPDLREMVEGQQRVTSTGHTTATSLSSSSSSARTSSRHLRQLTANGSETGCGSRAGTKRSGSKQMSSATSSKKSTSTSSISGSNSNSKTNSYLSSYGVDSYNVQCVATSTNSSDVSSGFFSISEVVSAADADAAAKAAAACKTERRARCFECEMCSYNFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01320605;
90% Identity: -
80% Identity: -