Scal004365.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Scaptomyza caliginosa
Gene Symbol
ken
Assembly
GCA_035044725.1
Location
JAWNNR010000214.1:592477-594310[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 5.8e-22 1.3e-19 70.2 0.1 7 104 23 119 18 125 0.91

Sequence Information

Coding Sequence
atgttgatgttgcaatACAGCAAGCATGGCGAGTGCATCCTCAAAGAAATCGGCGCAGCTTTTAGAGGAGAGCATCCAGCTGACTTAACTATCGTATGTGAGAACAAGGTGAAGCTGCATGCCCACAAATTAGTACTAGCCGCTGCCAGTCCACTTATACGAAACCTATTGGAGGATACTCATTTAAGTGATTGCACAACAACGGTTTATTTTCCGGATGTGAatgcaacatattttaaatttttattggaTTTCTTGTATTCGGGTCAGACGTGTATAACGTCACGTGATGTTAACTATCTGCATgatttattgctattgctacaAATCAAATCGGACAGTTGGAAGACAACAGATTCAGCATATTTGAGTAGTAAATGCGCCAGTTTACGCGAAAGACCgcgcaagcaacagcaatatgcATCTTCTCAATCGCTGGATCAGTCCCTGAAATACGAAGTCGAGAGTGTGGATGAGTCACGAAATGCGGCAAACTTTTCCACATTCTCCGCAGAGAATTGTGAGAGCGCTAACGAGTGTGCGAATAAGGATAttaacgatgatgatgacgattgTACGGCTAGAGATATTAAGGACAATAAGAGCGATGACAAAGACACGGATGAAGTTGTTAACCTTTCCAACATTCCAGCTGGTGGActtgccaacaataataataatactaatagcaacaacaataacaattcgaCAATAAATCCAGTTAATCTATCGCTCGATCTGCGAAcgaaaagcgacaacaactcGGCACGCAATGATATTAGCAAATCCTTTCTATCcaaacaccacaacaacattgacacGATCAGCTCCAATGAGAGCACAAAGCGTAAAGGTTTATTCTTTGACACCCACAAGGATGTAATGAAGCCACTGTCCGATGGCTCGGACATAAACAGTTCACCCGAGAACTATGTGGTAACGCCGCATCGAAAAAGACGACCCGGTTTTCATAATACCCAAAGCGATAATCAACCATTTACCACATATCAGCACAATCTGTTGGAGGAGTTGAGATTGGTTAAATCAACGACTTCGCCAATATCGGGCTTAGTTGCGGAAAAGAACCTACTATCACATCTGGAGGATGGCGCACTCAACACGGACACTCTAACACCGGAACGTAAACTATTggaaacacaacagcagcagcagcagcaacagcaacaacagcaacaacaacagcagcagcaacatcaacgcAATCATCGTGGTCAGAGTCCAGagctgcaaatgcatttgggcCAACAGTTTGTCTACCAATGGCAATCGAATCAGAATGCAGCCATCTCAGCAATGCCCAATTTGCAATCGCGCCTCTCGAGCTTATCACACATCAACCTAAATCTCGATCCAGATggtcgcaacaacaatagcagcaccATCGTTGccgccaacaataataatacccACTcaacatcatcgtcatcgtcggtGCGCGAATATCGTTGCGAATACTGTGGCAAACAGTTTGGCATGTCCTGGAACCTGAAGACACATCTCCGCGTTCACACCGGCGAGAAGCCGTTTGCATGTCGTCTATGCGTTGcaatgtttaaacaaaaggCCCACTTGCTTAAGCACTTGTGTTCGGTGCATCGAAATgttataacaacaacgaatggCACGGATACAGAGAATCGTTAtagctgctgtttctgttcgATGTGCTTTGAGTCTGTACAGGAGCTAGTGCGTCATTTGTCTGGGCATCATAACAATCTGTTGCTCACCAAGAATCTTCGGGAATAA
Protein Sequence
MLMLQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSDCTTTVYFPDVNATYFKFLLDFLYSGQTCITSRDVNYLHDLLLLLQIKSDSWKTTDSAYLSSKCASLRERPRKQQQYASSQSLDQSLKYEVESVDESRNAANFSTFSAENCESANECANKDINDDDDDCTARDIKDNKSDDKDTDEVVNLSNIPAGGLANNNNNTNSNNNNNSTINPVNLSLDLRTKSDNNSARNDISKSFLSKHHNNIDTISSNESTKRKGLFFDTHKDVMKPLSDGSDINSSPENYVVTPHRKRRPGFHNTQSDNQPFTTYQHNLLEELRLVKSTTSPISGLVAEKNLLSHLEDGALNTDTLTPERKLLETQQQQQQQQQQQQQQQQQQHQRNHRGQSPELQMHLGQQFVYQWQSNQNAAISAMPNLQSRLSSLSHINLNLDPDGRNNNSSTIVAANNNNTHSTSSSSSVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVITTTNGTDTENRYSCCFCSMCFESVQELVRHLSGHHNNLLLTKNLRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00557538; iTF_00498246; iTF_00542534; iTF_00518535; iTF_00498505; iTF_00542793; iTF_00518794; iTF_00557295; iTF_00607457; iTF_00497506; iTF_00560390; iTF_00610279; iTF_00495498; iTF_00607178; iTF_00482349; iTF_00497782; iTF_00610006; iTF_00495223; iTF_00482622; iTF_00560672; iTF_00616290; iTF_00616545; iTF_00486211; iTF_00570487; iTF_00570746; iTF_00485951; iTF_00558820; iTF_00567173; iTF_00574442; iTF_00574160; iTF_00497014; iTF_00496727; iTF_00559127; iTF_00566903; iTF_00597496; iTF_00521499; iTF_00597787; iTF_00521788; iTF_00522309; iTF_00596295; iTF_00596035; iTF_00525259; iTF_00502158; iTF_00501899; iTF_00593487; iTF_00593488; iTF_00593214; iTF_00593215; iTF_00565011; iTF_00564748; iTF_00583315; iTF_00583055; iTF_00511382; iTF_00553398; iTF_00553128; iTF_00598969; iTF_00599219; iTF_00514267; iTF_00514530; iTF_00528155; iTF_00528430; iTF_00552411; iTF_00499676; iTF_00499937; iTF_00513820; iTF_00513556; iTF_00517084; iTF_00517346; iTF_00548924; iTF_00535421; iTF_00543845; iTF_00498974; iTF_00576702; iTF_00576438; iTF_00500415; iTF_00620223; iTF_00619957; iTF_00577152; iTF_00577406; iTF_01322281; iTF_01322023; iTF_01321290; iTF_01326032; iTF_01325762; iTF_00538578; iTF_00538322; iTF_01326803; iTF_01326513; iTF_00508438; iTF_00508714; iTF_01324535; iTF_01324237; iTF_01327991; iTF_01325016; iTF_01322750; iTF_01323011; iTF_01327262; iTF_01323487; iTF_01323751;
90% Identity
iTF_01322281;
80% Identity
-