Sleb006892.1
Basic Information
- Gene Symbol
- ftz-f1_1
- Assembly
- GCA_003285725.2
- Location
- NW:17196669-17259581[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.016 1.1e+02 1.6 0.6 45 74 46 75 9 216 0.63 2 4 1.8 1.2e+04 -5.2 17.5 42 180 269 426 246 440 0.45 3 4 5e-19 3.3e-15 56.0 0.6 1 76 614 689 614 714 0.71 4 4 3.5e-71 2.3e-67 227.7 3.2 157 408 805 1049 788 1051 0.91
Sequence Information
- Coding Sequence
- ATGGACACCTTCCACGTACCTATGTTAGCGGAGAGTAGCAGTAATATTGGTTATGCCAACGATGCCATAATTAGcatcaataataatagtaataataacaacaatgataacagcaacaacaatcaccaTCAAGTGCAAACGCACCATCAGTTGCAGCATccgcaacagcatcagcaacagcagcagcaacagcaacaattgctgCCACATCATCACAAAGATCAAATGCTTGGGGCAGGCAGCACACCAATGCTGCCTTTCATCAACTATGGCCAGATGCAGCAGAAGGAGGACAGTGGTGTGGAGGTCACAGATAACGCAGATTTCGGTTGCATGCAACCGAATGCGTTGCAGCCAATCGATGGCAGCCACCTGGACGGGGGCATTTCATTGGGGGGTCTGTGCGATCGCATGTTTGCCAGCCCGAATCCCCATAACACCAACAATCTGACCTTGATGGGTGCCGGCAATGTAGAGGCTAAGGCAAGTGTTAGCAGCGGCGGCGTCTCCGGCAGACCCTCAAGCGGTGGCGCTATTGTCTTAGAATCCGTATCTGTGCCATCttttgccaatttattgttCCCGAACCGTGCTCAGACACAGACGACCGACACTGTCAACAGCATCGATCCTGCGCTGCTGCAGAAGGCGCCGCCCACAACCGCCGTCGAGTATCATCAGCTGAAGCCTTTGGAGAATCCCGCCACATCAGCCCCTGGGCCCACCTCTAGCTTTCTCAGCTCAACGACTGCACAGTTGCTCGAATTTGATGTTGCCAGTACTGcgaataccaacaacaacaataaacagcaCTCGGAGGACGTTAGTGTAATTCAAGTGCATGGTcagcgcaacaacaataacaccaacaacaacaacaacaacagtaaccataataacagcaacaataacttGGCTGACAATCACATCAGCAccacaacaactgcaacaacaataataagaaaCACTGCCAATCAGCAACAGTCgtcccaacaacagcaacagcaacaacaacaaagaaaatcGTTGCATAGCATTGAAGAATTGGCTGCAAGTTCCTGTGGGCCTAAAACCTCGCCACACTCTCAGACGCCCACCCCCAACCACCACCacagtaataataacaatagcgATAAAAATAACGCCAGCATCAGTAATCATAATATttgcaacaaccacaacaccAATACTAACAAGAGCAATAGTAGCGGTACacggcaacatcaacaacaacaactgcatgGACCGCACAGCGTTTCAAATCTCAGTTCCGAAGAGGAGTCCATGTCGGAGGATGAATTTGGCTTAGAAATTGACGATCAAGGAGGCTATCAGGACACCACCTCGTCGCATTCGCAACAGAGTGGTGGCGGCGggggtggtggcggcggcgggCCAGGTGGAGGAGGTGGCACCAGTGCCACCAATTCAGCGCTCCTCAATGGCAGCGGCGGCAACGCTGTTGGTGCCGGTGGCTACATGCTGCTGCCGCAGGCTGCCAGCTCCAGTGGCCACATGCCCGGCAGCGtcggtggcggtggcagcgGCACACACGGAACTCCATGCGGCACCAGCGCCACCTCAGGCGTCAGTGGCGAGGCTATCGATTTCAAGCATCTCTTCGAGGAGCTCTGCCCCGTCTGTGGGGACAAGGTGAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGTACGGTACAAAACAAGAAGGTCTACACCTGTGTGGCGGAACGTTCCTGCCACATCGATAAGACGCAGCGCAAACGGTGTCCATACTGCCGCTTCCAAAAGTGTCTCGAGGTGGGAATGAAGCTGGAAGCTGTTCGTGCGGATCGAATGCGTGGTGGACGCAACAAATTCGGACCTATGTACAAACGGGATCGGGCGCGAAAATTGCAGGTGATGCGCCAAAGACAATTGGCCCTTCAGGCACTGCGCAATTCCATGGGCACGGACATAAAGCCGACGCCACTCTCGCCGGGCTATCAGCAAGCATATccaaatatgaatattaagCAAGAAATTCAAATACCTCAGGTATCCTCACTCACGCAGTCGCCAGACTCATCGCCCAGCCCCATAGCCATTGCCTTGGGTCAGGTGAATGCCAGCACGGGCGGCGTGATAGCGACACCCATGAATGGCGGCGGCAACGGAGGCGCTGTGGGCAatggcaatagcaacaacaacagcagctctGGCAGTGGTGGAGGAGGCGGCGGCAGTGGGGGCGGCAATTTGGGCGGCAACACAAACAGCGGCGACGGCCTCCAGCGcaatggcggcggcggcaacggcagcagcagtggcagcggaTGTCACGAGGGCGGCACAGGATCTCTGCAGAATACAGCCGAATCGAAATTGTGCTTCGATTCCGGCACGCATCCATCGAGCACAGCCGATGCGCTGATCGAACCACTGAGGGTCTCACCGATGATACGAGAATTCGTGCAATCCATTGACGATCGGGAATGGCAGACGCAACTCTTCGCGCTGTTGCAGAAACAGACGTACAACCAAGTCGAAGTGGATCTCTTTGAGCTGATGTGTAAAGTGCTCGATCAGAATTTGTTCTCACAAGTGGATTGGGCAAGGAATACGGTCTTCTTTAAGGATTTGAAgGTCGATGATCAAATGAAGCTGCTGCAGCACTCCTGGTCCGATATGCTGGTGTTGGATCATCTGCACCATCGCATCCACAACGGACTGCCCGACGAGACGCAGCTGAATAACGGTCAGGTCTTCAATCTGATGAGTCTGGGTCTACTGGGTGTACCGCAGCTGAGCGATTACTTCAATGAGTTGCAGAACAAGCTGCAGGACCTCAAGTTCGACATGGGCGATTATGTGTGCATGAAATTCCTAATTCTGCTGAATCCAGATGTGCGcggcataattaataaaaagacCGTCTTGGAGGGTCACGAGAATGTGCAGGCGGCTCTGTTGGACTACACGCTGACGTGTTATCCTTCAGTGAATGAGAAATTCAGGAGGCTATTGAACATACTACCCGAGATCCATGCCATGGCGGCGCGTGGCGAGGAACATCTTTACTCCAAACATTGTGCCGGCAGCGCGCCCACCCAGACCCTGCTCATGGAGATGTTGCATGCCAAGCGGAAGGTGTAA
- Protein Sequence
- MDTFHVPMLAESSSNIGYANDAIISINNNSNNNNNDNSNNNHHQVQTHHQLQHPQQHQQQQQQQQQLLPHHHKDQMLGAGSTPMLPFINYGQMQQKEDSGVEVTDNADFGCMQPNALQPIDGSHLDGGISLGGLCDRMFASPNPHNTNNLTLMGAGNVEAKASVSSGGVSGRPSSGGAIVLESVSVPSFANLLFPNRAQTQTTDTVNSIDPALLQKAPPTTAVEYHQLKPLENPATSAPGPTSSFLSSTTAQLLEFDVASTANTNNNNKQHSEDVSVIQVHGQRNNNNTNNNNNNSNHNNSNNNLADNHISTTTTATTIIRNTANQQQSSQQQQQQQQQRKSLHSIEELAASSCGPKTSPHSQTPTPNHHHSNNNNSDKNNASISNHNICNNHNTNTNKSNSSGTRQHQQQQLHGPHSVSNLSSEEESMSEDEFGLEIDDQGGYQDTTSSHSQQSGGGGGGGGGGPGGGGGTSATNSALLNGSGGNAVGAGGYMLLPQAASSSGHMPGSVGGGGSGTHGTPCGTSATSGVSGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNGGGNGGAVGNGNSNNNSSSGSGGGGGGSGGGNLGGNTNSGDGLQRNGGGGNGSSSGSGCHEGGTGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLSDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIINKKTVLEGHENVQAALLDYTLTCYPSVNEKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01319815;
- 90% Identity
- iTF_01319815;
- 80% Identity
- iTF_01319815;