Basic Information

Gene Symbol
-
Assembly
GCA_014635995.1
Location
CM025793.1:35373293-35374637[-]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 3.8e-09 8.2e-06 26.5 5.6 1 45 53 99 53 108 0.80
2 3 0.00012 0.26 12.1 0.5 1 20 125 144 125 147 0.91
3 3 0.00013 0.28 12.0 2.8 51 70 149 168 142 168 0.78

Sequence Information

Coding Sequence
ATGACCAATACTAATGAACAAAAACCAGCCAACGTTGAAGTGGTCATTGATAAAAAGGCACAAAAAGCGGGTGAAAAAATGCTACTCGCCCAGAAGGAGCAGGAAATCTATAATAATTTTGCAACACCTTTAGTGGGCACCTATTTGAATCTGACCGATCAGCCAGCACTGATTAAATGTCCCAGTTGTGGCGCCCAAGAAATGAGCCAAGTGgtaaatgatttgaaatggTGGGCTGCAGAAATTAATAGTTTTCTAGGCTGTTTATTTGTAActttatgctgttgttgttgcctggaCTATAAACAGCCGTTTAATTCCAGCCTTATTATGTCGGATTCTATACCAGCACCTGCATATTTTGCTGTTGGTCCTCAACCCCATGAAGTTTCTTGTCCATTCTGTAAACAATATGGCAAAACTATAATGAAACGTTGTTTCTTTCGTTGCTGCTTAAGGCGCCACTATTGTTCAGAATGTGGTGAATATTTGGGCTCTTACAGACGTCCCCAGTTGTAG
Protein Sequence
MTNTNEQKPANVEVVIDKKAQKAGEKMLLAQKEQEIYNNFATPLVGTYLNLTDQPALIKCPSCGAQEMSQVVNDLKWWAAEINSFLGCLFVTLCCCCCLDYKQPFNSSLIMSDSIPAPAYFAVGPQPHEVSCPFCKQYGKTIMKRCFFRCCLRRHYCSECGEYLGSYRRPQL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-