Basic Information

Insect: Sarcophaga peregrina
Gene Symbol: foxj1b
Assembly: GCA_014635995.1
Location: CM025791.1:54813671-54818635[-]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2.6 3.7e+03 -1.3 0.1 15 49 25 60 23 65 0.74

2 3 3.4e-30 4.9e-27 94.5 0.1 1 79 207 282 207 291 0.94

3 3 9.4 1.3e+04 -3.0 0.1 60 71 311 322 304 339 0.51

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2.6	3.7e+03	-1.3	0.1	15	49	25	60	23	65	0.74
2	3	3.4e-30	4.9e-27	94.5	0.1	1	79	207	282	207	291	0.94
3	3	9.4	1.3e+04	-3.0	0.1	60	71	311	322	304	339	0.51

Sequence Information

Coding Sequence: ATGAAgacaaatatagaaaaaaacatttatttggaGCATGATGATAAGTTGAAGGCTGAAGACATAGATAAAATATCTGGCGAGCAaggcaaaaaaactaaaacaaatgaTATACTTAAACACTTTAATGAGCAAACTAAATTCGATTCAAATGATGAAAATGtagagaattataaaaattgcacAAATAGTAATGGAGATAATGATGTGgaagatgaagatgatgaaagagatttaacaaatttaaattggcTTACAGAACTTCGTAACCAGACGATCGGCTTTGTGAATATAGCTTTAGAAGAAGAGCCGAGAACGAGAAATGAAGCTGCTGTCACTGAAAAACCCAGAACATTGCTATCATTAACACCTCATTGTCAATACATGCAAGGAAGCACATTATGTGAAGCTACTGAAAATGTTTTAGAGCATAAAAAACAAAGTGATGTATTACAAGTAACACAGCAAAATTCTGTAGAACGAAGGAATGCCATGAGAATATCTCACCAACAGAAACGTCCCTCTCCGACAGAacgttatgaaatatttttaaataaaatcagaagagATCTAGAAACTTACCATAAATCAGCTACTGATTACCAATTGGATGCCGTTGAGAAACCTCCCTTCAATTATTCTCATATCATTGGAATGGCCATGTTAGATAACGGCAGACGTATGACATTGCAACAAATTTGCTCAtggattgaaaaaaaatttgctttttttcggGTTCGAAAGAAATGGAATaattcaATACGCCACAATTTGTCACTTCATTCATGTTTTCGAAAGATGGGACGCAATAAGGAGGACAGGGGAAAAGGTGGTTATTGGGAATTAGGCGTCGATCCAAAAAAATGCGACCGTAAACGTATACGTAATCGAAAATCTTTAagccaaacaacaaaaaaaaatcttcagaacCAATACATAAAAACATCAAGAagacgacaacaaaatttgcaaaGTTTGAATTTTCAAAGCATAAAAAAGTCTACCTTCAAACAacttcatgaaatattttcaagcaaATGCGAAGATCAATTACTATGTGCGACGAATAACAATCAAGGCGAAACAGTTGCTTGCTCTcgcaataataattttcttattaaaaccatcgaaacaaatcaaaattccAATATACATTGCGATGAAAAAATTTGTGTAAGAGAAATAAGAAATCGGAGCACCTCGCAAGAGAAATGtgatttcaaagaatttaaaaatagtacTGAAATCAATACTGCTGATCAAGATATGTGTCTCGGGCAGATATCAAAGCAATTCTGTCAACAACACAAGCGACTTCATAATGTTCATCAAGACGAGAATAAATTCGACACATTGATTATAAGTTCAAATGCGAACACTGAAATGccaaatatacaaaatttaccCACAGATCAGCAAGAGACTACCGATAGTTTTGCTCTTCCCGTAATCGATGATGTATTGCTTAAAGTACAGAGTGCATGA
Protein Sequence: MKTNIEKNIYLEHDDKLKAEDIDKISGEQGKKTKTNDILKHFNEQTKFDSNDENVENYKNCTNSNGDNDVEDEDDERDLTNLNWLTELRNQTIGFVNIALEEEPRTRNEAAVTEKPRTLLSLTPHCQYMQGSTLCEATENVLEHKKQSDVLQVTQQNSVERRNAMRISHQQKRPSPTERYEIFLNKIRRDLETYHKSATDYQLDAVEKPPFNYSHIIGMAMLDNGRRMTLQQICSWIEKKFAFFRVRKKWNNSIRHNLSLHSCFRKMGRNKEDRGKGGYWELGVDPKKCDRKRIRNRKSLSQTTKKNLQNQYIKTSRRRQQNLQSLNFQSIKKSTFKQLHEIFSSKCEDQLLCATNNNQGETVACSRNNNFLIKTIETNQNSNIHCDEKICVREIRNRSTSQEKCDFKEFKNSTEINTADQDMCLGQISKQFCQQHKRLHNVHQDENKFDTLIISSNANTEMPNIQNLPTDQQETTDSFALPVIDDVLLKVQSA*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01315303; iTF_01312844;
90% Identity: -
80% Identity: -