Scar028584.1
Basic Information
- Insect
- Sarcophaga carnaria
- Gene Symbol
- egg
- Assembly
- GCA_958299815.1
- Location
- OY283153.1:36818859-36824107[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 6.7e-13 5.1e-09 36.7 0.0 5 75 1039 1102 1036 1104 0.90
Sequence Information
- Coding Sequence
- atggaaaataaaaatgaattaatagaTGAACACCTTAGTGATACTGAAATTACCACAGCCGGGACAACAAATACAGAAATGCCGGTTTTGGAAAACTTCTTTACGGCTGAAGCTGGTGGCACCAGTGTTTCGAAATCAGAAATTGTGAAtacaacattaaaattaaatgaacagaCCGAAGATAGTGCAGCTACTTTACCCGACAAAGATGCGGCATCAAGCATGATTCTGTCACAAGATCCTGCAAATGAGGCAGAGCCTCCAAATGTAACAGAACCTCCAAATGTGGCAGAGAACACAACAGatATCGCTGTCAAGCCTCCCATTGAAAATGTATCACCGGGGTTGGATTCTAATCTTGAGAGCGCAAATCAAACAGAGGCTCCAAAGCAAACAGAAGTTCCTACAAATATTGACGGTGAAAAAACGactgaaaatcttaaaattatttcagaagATATTTTAGAAACACCAGTTGAAGAGCTTTGTACACTGGAGGTCAAGACTAAACAAGCGAAAGAAGCTCTAGAGCAAAACAATTTAGACGAAACTGATAACGaatcaaaagaaactgaaaaaagtTCAAaggataatgaaaataataacccagaagaaaataaaacttcagaaCCAAAGCCCTCAGAAATGTCCAATGAGCCAATAGACTCTCAAAATGAATCTCCAgctgaaataaacaaaaataaagacatATTAGCAACAGAAAATCTTAAAGACGTTGGCGAAAAGTCCTCAATTGTTGCTGCAAATGAAGCAAaggaaaacgaaattttacCAACTGAAGAAATTGAACCTATGGATACTTGTGATAGCCAAGAatccttaaatttaattatagatGAAACATCAAATATTACTGAGAACAAAGATGATTTATCGGATAACAATAAAACCGATGAAGATACTAATATGGAAGTGGAATTTAATGAACACAGTTCAGCTGCCATAAAAGACCCAAATGATAAAGGCcaagatgaaaaagaaaaaaccgaaGCTAAAGACGAAGACCAAGaagctttaaataaattgaaagatgATGATGTTATACCTATAGAACAGCCGCCAGTGCCTATAATTGAAattgatgatgaagatgatatTGAGCCTACAGATTCCATACAGACCTCAGCGAAGGAAGGTGAAGAGAAGCAAACGCCAATGGACGTTGACGAAAAGACTCAAGCGGTTGTTTCTGAGAAAGAAACATCTTCCACTGAAAACGGCAACGATACAAGTAAAAGCGAAAAAATTGAAACCCAACAGAAGGCGGAAGAGAATTTATTAGAAGTGACTTCAGAGAAACCTTTAGAAGAACATTTAGGAACTCAAGTATCAAAGATTTCAGAAGATGACGATGACACTGAAGATGCCACAGTTGAAATATTCTACAATAAAGAATGCATTAATTATGAGTGTTCTCGTAATCACAAACAGTACTTTAGAGTGCCACAGTTTGCTTTTAGTTACTTTCAAGtaacgaaaaagaaatttaaagtgcAGTATATCTGTGCTGATTGCTATGACAAAGCATTAGAAATGTATGAGGAATTTTGTGGCTTAATAAGCTCTAAGCAACCTTTGCTGCTAGAGGAGATTCCATGTGGAAGACAAGAATTTGTGGAAATCATTGATAGCAGTGATGACGAGAATGCTACTAATGACAATGACAAACCTGCTGAATCTACAAAATCTGCGttttctcaaaatgatttatCCCTAATAGAAGCAGAGCTGCATAATACTATAAAATCAGTTTTAAGTAATCTTGAAATACAAAAGCAATTAACCTGGTCTAAAACCATACTAACGGAGAGGCTAAAGCGTTTGGAAGTGGAAACAGACTTTATAGATAATGAactaaaaactttacaaaaaaaggcTGACAAAATGCACGAAGGTTTATATTCGTgtcccaaaataaaaatacgacaGCTTCAACCATTAGATCTGAACAGTGGCAAACTTCTAACTTTAGATCAAGCTATGCAAAAGGAAATACAGCCCATACCACCGGTGGGAGAAATTGAAAGGCCCatcatacaaataaataatatttattatgctGTTAAAAATAATCCCATTGCCAGTTGGGTCCCTTGTCGTGTTATCGAGCAAGTAGAGGGCAGTATGTTGGCGCAGAAAAACGTCAAacactacaaaataaaatttataaaaaatctaaTCCAAATGCCCAAAACTGTACCAGCCAAATATTTGGCATACTATGATCCGCCATCTGTCAGATTACCTATAGGCACTAGAGTTATTGCATATTTTGATGCCACTTCTTTGGCTAGAGGTCGTGAAAAAATTAATGTGCAAAGCGCCTTTTATCCAGGCATTATTGCAGAACCCTTAAAGCCGAACAATAAATTCagatatttaattttctatgatGATGGCTACACTCAATATGTATACCACAAGGATGTACGTTTAGTATGTCACGTGTCCGATTGTGTTTGGGAGGATGTTCATCCTGCCTCAAGAGATTTTATACAGAAATACTTAACCCAATACTCCATTAATCGTCCTATGGTTCAAACACAAAAGGGACAATCAATGAATACCGAGTCAAATGGCTATTGGTTGCATGCCCGTGTAGTGGATATCGACTGTAGTTTGGTGTTAATGCAATTTGAAGGTAGTAAGAGTCACACTGAATGGATTTATAGAGGATCATTACGTTTAGGTCCTGTTTTTAAAGAGTATCAGAAATCCTTACAAAAGAATTCTACTGTGCCAGTGTCACGTTTACCGAGGCGCACTGAACCATTTATTCGTTATACCGAAGATGAAGAAAATACTTCGCAACAGCAAGCTGATAAATCGAATGATAATAGTCGAGCAGTGGCTCGTAAAACTTTTGGTAGACCTGAATCAATGATGAATTCTGCCTCAACaagtcaacaacaacagcctcTGCCTGttgtaaaacatttaaacaattcCACAATTTATGTAGAGGatgaaaataaaccaaaagGAAAGGTTGTCTACTATACAGCTAAACGCAATCTACCTCCTCGCAAATACAAACCGCACATTTGTTCACCTTCATGTCTCTTTGAAATTACTCATAATCTCAGTGCTTACAGTCCCTTATCGAAACCATTGCTGTCTGGCTGGGAACGTTTTATTAtaagacaaaaaattaaaagagttgTTACCTATCGTGCACCGTGTGGCAAAATTATGCGTAATATGAAGGAGTTACACCACTACTTGCGTACCACGCATAATGTTTTGAATGTGGATAATTTCGATTTCAGTCATGAAACGAATTGCTTAGCCGAGTATGTCATCGAAAGTGCTATTGTACAGAAACGTGATATATCAGGTGGCCAAGAAAAGATGGCTATACCATTGGTGAATTATTACGATAATACACTGCCACCAGAATGTAAATATTCAGCTAGAGTTATACCAACCGAAGGTGTAAATATCAATACCGATCCAGCTTTCTTGGTAGGATGTGACTGTGAAGATGACTGTATTgataaaaataaatgtgcTTGTTGGCAATTGACACTGGCTGGTGCTAAATATGGCAATCCAAATGCAGCGCCCGAAGAAGTTGGCTATCAATATAGACGTCTGTTGGATCATGTGCCAACTGGCATTTACGAATGTAATATCAACTGTAAATGCAAAAGCAGTTGCCTTAACCGTGTCGTACAAAATTCTTTAACCATGAAATTGCAAGTATTTAAAACTTCCAATCGTGGCTGGGGCTTACGTTGTATTAATGACATACCGCGCGgtagttttgtttgtgtttatgcCGGCCACCTGCTTACCGAAGCTAAAGCAAATGAGgGAGGACAAGATGCTGGCGATGAGTATTTTGCCGAGTTGGATTATATTGAAGTTGCCGAACAGATAAAAGAAGGTTACGAGTCTGAGGTAGAAATACCAGAACCGGAAGAAGAGGATCCCTACAATCCGGAAGGGGACGATGATGAGTTTACACCAAGTAAATCGTGGATGACAAGAGCAAGAAAACAAAACGCTACGAAATCGACACGTTCTTCAAATCAAGAAGAGGATTCCCAAGAGAGACAAGTAATAAATTTCAATCCAAATGCCGATATGAACGAGGACTCCGGCAGAGAAAATTCCATACGTAAACTATATGGAAAAGATGAAGCGTGTTATGTTATGGATGCAAAAATTTCTGGTAATTTGGGTCGCTATTTTAATCACTCTTGTTCACCCAATATGTTTGTACAAAATGTATTTGTCGAGACTCATGATTTACGTTTTCCTAATGTGGCATTCTTTTCATCTTGTAATATACGTGCTGGCACTGAATTAACTTGGAATTATAACTACGAAGTTGGTGTAGTACCGGGAAAAGTTTTGTATTGTCAATGCGGTGCCCCCAATTGTCGCTTGcgtttactttaa
- Protein Sequence
- MENKNELIDEHLSDTEITTAGTTNTEMPVLENFFTAEAGGTSVSKSEIVNTTLKLNEQTEDSAATLPDKDAASSMILSQDPANEAEPPNVTEPPNVAENTTDIAVKPPIENVSPGLDSNLESANQTEAPKQTEVPTNIDGEKTTENLKIISEDILETPVEELCTLEVKTKQAKEALEQNNLDETDNESKETEKSSKDNENNNPEENKTSEPKPSEMSNEPIDSQNESPAEINKNKDILATENLKDVGEKSSIVAANEAKENEILPTEEIEPMDTCDSQESLNLIIDETSNITENKDDLSDNNKTDEDTNMEVEFNEHSSAAIKDPNDKGQDEKEKTEAKDEDQEALNKLKDDDVIPIEQPPVPIIEIDDEDDIEPTDSIQTSAKEGEEKQTPMDVDEKTQAVVSEKETSSTENGNDTSKSEKIETQQKAEENLLEVTSEKPLEEHLGTQVSKISEDDDDTEDATVEIFYNKECINYECSRNHKQYFRVPQFAFSYFQVTKKKFKVQYICADCYDKALEMYEEFCGLISSKQPLLLEEIPCGRQEFVEIIDSSDDENATNDNDKPAESTKSAFSQNDLSLIEAELHNTIKSVLSNLEIQKQLTWSKTILTERLKRLEVETDFIDNELKTLQKKADKMHEGLYSCPKIKIRQLQPLDLNSGKLLTLDQAMQKEIQPIPPVGEIERPIIQINNIYYAVKNNPIASWVPCRVIEQVEGSMLAQKNVKHYKIKFIKNLIQMPKTVPAKYLAYYDPPSVRLPIGTRVIAYFDATSLARGREKINVQSAFYPGIIAEPLKPNNKFRYLIFYDDGYTQYVYHKDVRLVCHVSDCVWEDVHPASRDFIQKYLTQYSINRPMVQTQKGQSMNTESNGYWLHARVVDIDCSLVLMQFEGSKSHTEWIYRGSLRLGPVFKEYQKSLQKNSTVPVSRLPRRTEPFIRYTEDEENTSQQQADKSNDNSRAVARKTFGRPESMMNSASTSQQQQPLPVVKHLNNSTIYVEDENKPKGKVVYYTAKRNLPPRKYKPHICSPSCLFEITHNLSAYSPLSKPLLSGWERFIIRQKIKRVVTYRAPCGKIMRNMKELHHYLRTTHNVLNVDNFDFSHETNCLAEYVIESAIVQKRDISGGQEKMAIPLVNYYDNTLPPECKYSARVIPTEGVNINTDPAFLVGCDCEDDCIDKNKCACWQLTLAGAKYGNPNAAPEEVGYQYRRLLDHVPTGIYECNINCKCKSSCLNRVVQNSLTMKLQVFKTSNRGWGLRCINDIPRGSFVCVYAGHLLTEAKANEGGQDAGDEYFAELDYIEVAEQIKEGYESEVEIPEPEEEDPYNPEGDDDEFTPSKSWMTRARKQNATKSTRSSNQEEDSQERQVINFNPNADMNEDSGRENSIRKLYGKDEACYVMDAKISGNLGRYFNHSCSPNMFVQNVFVETHDLRFPNVAFFSSCNIRAGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01315502;
- 90% Identity
- iTF_01314678;
- 80% Identity
- -