Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.3e-05 0.078 13.1 0.1 21 46 148 172 142 175 0.82

2 5 0.0001 0.59 10.3 0.0 21 46 174 199 171 203 0.91

3 5 0.4 2.3e+03 -1.2 0.0 26 44 206 224 204 229 0.72

4 5 0.044 2.6e+02 1.8 0.1 27 46 237 253 233 260 0.69

5 5 0.01 59 3.9 0.1 21 51 284 314 274 315 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.3e-05	0.078	13.1	0.1	21	46	148	172	142	175	0.82
2	5	0.0001	0.59	10.3	0.0	21	46	174	199	171	203	0.91
3	5	0.4	2.3e+03	-1.2	0.0	26	44	206	224	204	229	0.72
4	5	0.044	2.6e+02	1.8	0.1	27	46	237	253	233	260	0.69
5	5	0.01	59	3.9	0.1	21	51	284	314	274	315	0.89

Coding Sequence: ATGGAGAACGTTTGTAGGACTTGTCTGAGGACAACTGATAATTTGTCACCACTCTACTCTAACAAGACATTGATTCTTAAAATTGAAACAATTTCTTCGATACAGATCGATACAAGCGATGCATTTCCTACTGTGATATGTGCGGAATGTACAGAAAATGTAGAAAGGCTCTACAACTTTCGTCTGgtgataataaataacgatAAAGACCTAAAAGAACGAATAGCAACTATCAATTCAGAGCAAACTGAAGACGAAAATGATAAACCATTAGGAGTCGGAACCGCGTCGTTATTATATGCAGTCGTTCCGCCTCAACAAGATGAAGTTTTAGATGAATCTCTGCAAAACGCTTTCAATAAGTTGAGATATTGTAAATGTAAAATATGCGGGAGGAGTTTCTCGTCACGATTCAAGCTCTACAACCACCGGAGGACTGAACACATAGCCCCAGGCGTTTGTAACATTTGCGGGGTCGTCGTCCGATCGGATAATCTCAAAAGACACGTTCAGATGCATTCGGCCAGTCCGGCACAGTGTCTGCACTGCGGCAAAGTGTTCAAAAATTCCGAATCGTTGAGAGGGCACCTGCAGATCCATAAAGGAATGGTTTTCACGTGCGAAATTTGTGGGAAACAGTCCAAAGTCAAAGCTGAATACAAACGACACATGAAGACGCACTTGAATCCGGAAATCCGGAAATCTGTGTGCACGATTTGTGGGAAGAAAGTGAGGGATTTGAAGAGGCACATTCAGAGCCACACCGGCGAGAAACCGTACAGTTGTGTTTACTGTAATCGCGGATTCACCAGCACTTACTCTTTGAAAGTTCACATTAGACAACACACGAATGAGAGACCCTATGTTTGCGAATTTTGTCCTATGTCTTTCCCTCAGAAAGTGTCTTTAAATACCCATTTGAAGTCcaaacataataataaaagttga
Protein Sequence: MENVCRTCLRTTDNLSPLYSNKTLILKIETISSIQIDTSDAFPTVICAECTENVERLYNFRLVIINNDKDLKERIATINSEQTEDENDKPLGVGTASLLYAVVPPQQDEVLDESLQNAFNKLRYCKCKICGRSFSSRFKLYNHRRTEHIAPGVCNICGVVVRSDNLKRHVQMHSASPAQCLHCGKVFKNSESLRGHLQIHKGMVFTCEICGKQSKVKAEYKRHMKTHLNPEIRKSVCTICGKKVRDLKRHIQSHTGEKPYSCVYCNRGFTSTYSLKVHIRQHTNERPYVCEFCPMSFPQKVSLNTHLKSKHNNKS

Sequence clustering based on sequence similarity using MMseqs2