Basic Information

Gene Symbol
-
Assembly
GCA_019009955.1
Location
GWHBAZH00000005:146755273-146761042[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 4.1 2.4e+02 2.6 0.5 1 9 116 124 116 133 0.72
2 20 0.018 1 10.0 0.7 1 23 186 209 186 209 0.96
3 20 0.036 2.1 9.0 1.0 1 23 215 238 215 238 0.94
4 20 0.00053 0.031 14.8 0.4 1 23 244 267 244 267 0.94
5 20 4.5e-05 0.0026 18.2 0.4 1 23 273 296 273 296 0.96
6 20 0.0013 0.076 13.6 0.7 1 23 302 325 302 325 0.94
7 20 0.001 0.058 14.0 0.1 1 23 331 354 331 354 0.95
8 20 0.0003 0.017 15.6 3.1 1 23 364 387 364 387 0.96
9 20 0.012 0.69 10.6 1.2 1 23 393 416 393 416 0.95
10 20 0.085 5 7.9 0.2 1 23 422 445 422 445 0.94
11 20 2.7e-05 0.0016 18.9 1.6 1 23 451 474 451 474 0.96
12 20 0.12 7.1 7.4 0.1 1 23 480 503 480 503 0.93
13 20 0.0012 0.069 13.7 0.5 1 23 509 532 509 532 0.95
14 20 0.00089 0.051 14.1 3.2 1 23 542 565 542 565 0.96
15 20 6.7e-05 0.0039 17.7 0.3 1 23 571 594 571 594 0.96
16 20 0.0005 0.029 14.9 0.3 1 23 600 623 600 623 0.94
17 20 5.5e-05 0.0032 17.9 2.2 1 23 629 652 629 652 0.97
18 20 0.00013 0.0073 16.8 4.4 1 23 662 685 662 685 0.96
19 20 0.036 2.1 9.1 2.4 1 23 691 714 691 714 0.93
20 20 0.0077 0.44 11.2 0.8 2 23 721 743 720 743 0.94

Sequence Information

Coding Sequence
ATGATTGCTGCTCCGGGAACTAGCCTTGATGGAGTTCCAGTCAATGAAAAACCTGACTGCTATTTGCATGACAAGCCATCTACTTCAGCTGCTGGAGTTGTAGATTCTGTTCCGAGCTCTATTATTAAAGAAGAGTATTCTTCGTACGAGGGAAGCCTCACATCTACAGCTGCTGGAGATATTGATATTGGGCCAAGCTTCATTATCAAAGAAGAGGATTCTTTGGATGAGGAAAGTCTCTGTATTCCTAGAGGCAGTGAACAAGTGTGGAAACCAATTAAACAGGAACCAGCTGTGGAACTAGGCACTTCTTATGGAGAGCTTGAACATAAAGATAAGGCAGTTTTCATCTGCCATCATTGCCAGCGAGCCTGGAAATCATTCATTTCACTGAGGCGCTGTGTTCAAAAGTGCTTCCATTCAACAGTCACTAAATTCAGCCTCAAAAAGTCACCATCCACTGGAGTAAATACTTCAAGAAGCTATAAAGGTTCAAGGGGAGAAGTGAATTTGTCTAAGGAACGCTTACCTGCAAGTGGTGGGGCTGAGAAATGCTTTGCGTGTTATGAATGCGGCTACAGCACTAATTATAGATACATTTTAAAACAGCACATACAGGTTAAACATTCAAATGACAAACTTCACTCCTGTCCCTACTGTGAACACAGTACTAGTTGGGCTAGTGCTCTAAAACTTCACATACAAGCTAAACATTTGAGTGTTAAACCTCATTCCTGCCCCTACTGTGAATATAGTGGTGTTCAGGCTCGTGATCTAAATCGTCACATCCAAGCTAAACATTTAAAGGTTAAACCTCACTCCTGTCCCTACTGTGAATACAGTGGTAGTCGGGCTGGGAATCTAAAAGTTCACATACAGGTTAAACATTTAAGTGTTAGACCTCACCCCTGCCCCTATTGTGAATATACTGCAGTCCAGCTTGTTAATCTAAAGCATCACATAATGGCTAAACATTCATACGAAAAACCTTACTCCTGCCCCCATTGCGAATACGCTGCTGTTCGGGCTGACAGTCTAAAGGAACACATACTTGCTAATCATTCAAACGACAACTCATCATTGCAACCTCACTCCTGCCCCCACTGCGAATTCACTTCGGTTAGGTCTGGCGATTTAAAACGCCACATACAGAGTAAACACTTAAGTGTTAAACCTCACTCCTGCCCCGACTGTGAATACAGTACTGTTCGGGCTCGTGATCTAAAATTCCACATACAGAGTAAACATTTAAGTGTTAAACCTCACTCCTGCCCAGACTGTGAATACAGTACTGCTTGGGCTCGTGATCTAAAACTTCACATACAGGCTAAACATCAAAGTGTTAAACCTCATTCCTGCCCCTACTGTGAATACAGTTGTGTTCGGGCTGGTAATCTAAAAGTTCACATACAGATTAAACATTTAAGTGTTAAACTTCACTCCTGCCCTTACTGTGAATACAGTACTGGTTGGGCTGGGGATCTAAAAGTTCATATACAGGGTCAACATTTAAGTGATAAACCTTACTCTTGCCCCCATTGCGAATACGCTGCTGTTCGGGCTAACCATCTAAAGGAACACATACTTGCTAATCATTCAAACGACAACTCATTTTTCAAACCTCATTCCTGCCCTCATTGCGAATACAGTTCTGTTAGGTCTAGAGATTTAAAACTCCACATACAGAGTAAACATTTAAGTGTTAAACCTCACTCCTGCCCCTACTGTGAATACAGTACTGTTCGGGCTGGTGATCTAAAAGTTCACATACAGGTTAAACATTTAAGTGTTAAACTTCACTCCTGCCCTTACTGTGAATACAGTACTGGTAGGGCTGGGGATCTAAAAGTTCACATACAGGCAAAACATTTTAGAGATAAACCTTACTCCTGCCCACATTGCGAATACAGTGGTGCTCGGTCTGGCCATCTAAAGCGTCACATACTGTCTAAACATTCAAATGACCACCCATCATTCCAACCTCACTCCTGCCCCCATTGCGAATACAGTTCTGTTAGGTCTAGGGATTTAAAACGCCACATGCAGAGTAAACATTTAAGTGTTAAATCTCACTCCTGCCCCTACTGTGAATACAGTACTGGTCGGGCTAGTGATCTAAAATGTCACATACAGGGAAAACATGTAAGTGTTAAAACTCTGTCGTGCTTCTTTTGTGAATACAGTACTGCTCGGAGAGGCAGTCTGAAATCTCACATAAAAGCTAAGCATTGTAGAGAGAAATCTCCCTTATAG
Protein Sequence
MIAAPGTSLDGVPVNEKPDCYLHDKPSTSAAGVVDSVPSSIIKEEYSSYEGSLTSTAAGDIDIGPSFIIKEEDSLDEESLCIPRGSEQVWKPIKQEPAVELGTSYGELEHKDKAVFICHHCQRAWKSFISLRRCVQKCFHSTVTKFSLKKSPSTGVNTSRSYKGSRGEVNLSKERLPASGGAEKCFACYECGYSTNYRYILKQHIQVKHSNDKLHSCPYCEHSTSWASALKLHIQAKHLSVKPHSCPYCEYSGVQARDLNRHIQAKHLKVKPHSCPYCEYSGSRAGNLKVHIQVKHLSVRPHPCPYCEYTAVQLVNLKHHIMAKHSYEKPYSCPHCEYAAVRADSLKEHILANHSNDNSSLQPHSCPHCEFTSVRSGDLKRHIQSKHLSVKPHSCPDCEYSTVRARDLKFHIQSKHLSVKPHSCPDCEYSTAWARDLKLHIQAKHQSVKPHSCPYCEYSCVRAGNLKVHIQIKHLSVKLHSCPYCEYSTGWAGDLKVHIQGQHLSDKPYSCPHCEYAAVRANHLKEHILANHSNDNSFFKPHSCPHCEYSSVRSRDLKLHIQSKHLSVKPHSCPYCEYSTVRAGDLKVHIQVKHLSVKLHSCPYCEYSTGRAGDLKVHIQAKHFRDKPYSCPHCEYSGARSGHLKRHILSKHSNDHPSFQPHSCPHCEYSSVRSRDLKRHMQSKHLSVKSHSCPYCEYSTGRASDLKCHIQGKHVSVKTLSCFFCEYSTARRGSLKSHIKAKHCREKSPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01309973;
90% Identity
iTF_01309973;
80% Identity
iTF_01309973;