Rarc042028.1
Basic Information
- Insect
- Ricinus arcuatus
- Gene Symbol
- Mbd2
- Assembly
- GCA_027475445.1
- Location
- JAOXJT010000013.1:3030717-3035067[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 3.6e-13 2.5e-09 37.8 0.0 7 72 26 85 21 89 0.87 2 2 6.6e-16 4.7e-12 46.5 0.0 9 71 297 355 291 358 0.90
Sequence Information
- Coding Sequence
- ATGGGTGGTGAAACTGAAGAAAAAGGTAAATTAAATGAAAACAAAAAGGAAAAAAATATTATAATTGAAGATCAACTGATGAAACCATTTAATGTTGGATGGAAAAGAGAAGTTGTGATGAGAGTCATTACAGCAAGCAACAATTGTGATGTCTATTATCTACATCCTAGTGGAAAGAAACTAAGATCTATGATTGAAGTAAAAGCAAATTTGACTGATGGGTTAACACCTGATTGTTTCACTTTCAAAAAGGTGCCTTTAAATGTAAGCTCAGAAATTGTTCGCACAGCTTCGGTTCGAGGAAAAAATAACAAGAAAGCAAAAAAAATTAATCAAATAATCAAGAACAATAGTCAAGGGCAAATGATGATAAAAAATTCGAGTTTGATTAATAAAGAAAAATCAACTCATCAGAGATCAAACACTCGAACACAGAAAATGGTAAAGAAAAGGGAGGTCGAAAACAAAATTTTAGACATTAAAAAAGCAAAGAATGTTAACGGAATATCAAAAAAGAAAAATATTAAGACTGTTGAAAAAGGCAGAAGAGCCCCAAATTATATAGCAAGTTCTGGAAGGCAAAATAAAACTGAAATTAATAAAAAGGCTGGACTTAGAAAATCGAATATCATAAAACTTAATCCTAAAGAATCTACTTCCTCCAAAATTAAAATTGACAATATAAATGGAGGAAGAAAAAGGGAATTAAATGATATCAAGAGCATAGTCAAGAGAAATATTGGAAAATATAGAGAAATGAGAAAAAAGCAAATTATGGGAAAAATGAAAGAAGGTTTACGTGAAAAATCTACTAGAAATATTCCTTATAATGTAATGGAAAGATCAAGAAGATCAGAACCTATTTCGAAGAATTTACATATATATTTAAAACCCCTGGAAAGGGGTTGGAGAAGAGAACTGGTACATAGAGTAAATGGGCTGTGTTCTGCGGGGCGGTCTGATGTTTATTATTTTCATCCAAGTGGTAAAAAACTCAGATCAATCCGAGAAATTGCCAAAAATCTTACTCAAGGCCTAACTTTAGAGTGTTTCACATTTAGGAAAGAAGCCCTAGGCTGCGGGGAACCTCAGGAAGTCGTCAGAAATGCCAGATTAAGTAAAACTGGTATACCTGCAAGTTAA
- Protein Sequence
- MGGETEEKGKLNENKKEKNIIIEDQLMKPFNVGWKREVVMRVITASNNCDVYYLHPSGKKLRSMIEVKANLTDGLTPDCFTFKKVPLNVSSEIVRTASVRGKNNKKAKKINQIIKNNSQGQMMIKNSSLINKEKSTHQRSNTRTQKMVKKREVENKILDIKKAKNVNGISKKKNIKTVEKGRRAPNYIASSGRQNKTEINKKAGLRKSNIIKLNPKESTSSKIKIDNINGGRKRELNDIKSIVKRNIGKYREMRKKQIMGKMKEGLREKSTRNIPYNVMERSRRSEPISKNLHIYLKPLERGWRRELVHRVNGLCSAGRSDVYYFHPSGKKLRSIREIAKNLTQGLTLECFTFRKEALGCGEPQEVVRNARLSKTGIPAS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01308693;
- 90% Identity
- iTF_01308693;
- 80% Identity
- iTF_01308693;