Rexs019964.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Rhorus exstirpatorius
Gene Symbol
KLHL10
Assembly
GCA_963564615.1
Location
OY751321.1:24415768-24420653[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 5.5e-27 1.3e-24 86.8 0.0 2 109 54 160 53 161 0.94

Sequence Information

Coding Sequence
ATGGACGTAGATCCGAATGACAGCAACATCAGCAGTGTAAGTGGCACGACAGATGCGAACaacaattttctcatttttgacGGAAATAGCTCGAACGCAAAGCGTCTCATTGCCTCAAATGGTGGAAGATGCATGAGCACGCAGGCTATGCAATCGTTGTACGATCTGCGACAGAACAATGTACTTTGCGATGCGGTTCTCAGGCTCGAGGACGGCGGTGTATTTCCCATTCATCGGGCAATACTGTCAGCTTGCAGCAATTATTTCAGgaccCTCTTCACGACGACGTTGCACTCTCGCGAGCGTACGGACATTCTTCTGCCGGGTGTGAATAGCCCAATGATGAATCATCTACTCGAGTACGCGTATCTTCGCTCCCTCGACATTAATCCCGGCAACGTGTGTCAATTGCTCGTAACGGCTGACTATCTGAGCGTGACAGGAGTTCTCGATCTTTGCCGAGagtatttacgaaaaaatttgtcACCCGAGATATGCATGAGAGTACTGAGATTCGCGAGAGAACACTTTTGTCGCGGCCTCGAGCAGGATGCTTATCAATACGTCATGAGGCACTTTGTACTGGTAGCCCAGAGAAGCGAGGATCTTCTTCATCTGCCGATCGAAGAGCTGCGAAGTCTCGTCGGAGCCGATGACTTGAACGTCAAGAGCGAGGAGGTGGTCTGGGAATTGGTACTTAAATGGATAAATCATGATCCGGAGGCGCGTAAATGTCACATCGTCGATCTGCTGAAGAACATACGTCTCGGTCTATTGGatacggaattttttttggaaaaagtcAAGGATCATCCGTATGTGACGGGTAACGAGGCCTGTCGACCGATCATAATCGAGACACTGAAATTTCTCTATGATCTCGAGATGATAACGCAAAAACACGGCGAGGTACCGACACCGGAAATCGCAAGGCCCCGGGTACCTCACGAAATTCTTTTCGCTATCTGCGGCTGGATAGGCAACGGAGCGACGAGTTACATGGAGACTTACGATACTCGAGCGGATCGTTGGGTGCAGGTACGCGAGGAGGATCCTTCCGGGCCGCGAGCTTATCACGGTGTAGCCGCTGTCGGATTCAGCATTTACGTGGTGGGTGGATTCAACGGTCGCGATTATTTCAGCAGCTGTCGTTGCTTCAATGCCGTTACGAAAGAGTGGCGTGAGGTAGCTCCGATGAATGCGAGAAGGTGTTACGTGAGCGTTGCAGTCGTCGACGACGTTGTATTCGCGATGGGTGGTTACGACGGTCATTATCGGCAAAAAACAGCAGAACGTTACAATTATCGCACCAATCAGTGGTCACTGATAACGCCAATGGCCGTTCAGAGATCGGACGCTTCTGCGGCAACCCTCAATGGAAAGATTTACATTACGGGTGGTTTCAATGGTCAAGAGTGCTTGAGCTCGGCCGAGGTATACGATCCCGAGACAAATCAGTGGACAAGAATCGCACCGATGAGAACACGAAGAAGCGGACAGTCCTGCATCGCTTATCATGGCTGCATATACGTTATCGGTGGTTACAACGGAATCGCGAGAATGTACAGCGGTGAAAAATATAATCCGGCCACCAACACGTGGAGCCCGATACCGGACATGTACAATCCACGAAGTAATTTCGCGATCGAAGTTATCGACGACATGATATTCGCGATCGGTGGCTTCAACGGCGTAACGACGATATTTCACGTTGAGTGTTACGACGAGAAGACCAACGAGTGGTACGAAGCTACCGATATTGGACTTCATCGATCGGGCTTGTCGGCATGCGTGATCGTTGGACTGCCGAACGTTCAGGATTACATTCACAAGCATCGGGAACATTTGATGGAAGAGAAGAGGCAAAAATTATTGGCTCTGGAGTTTCAACgaaatcagcatcagcagcaggaGAATCAGCTGATTCaggacgagaatgacatatcaTAA
Protein Sequence
MDVDPNDSNISSVSGTTDANNNFLIFDGNSSNAKRLIASNGGRCMSTQAMQSLYDLRQNNVLCDAVLRLEDGGVFPIHRAILSACSNYFRTLFTTTLHSRERTDILLPGVNSPMMNHLLEYAYLRSLDINPGNVCQLLVTADYLSVTGVLDLCREYLRKNLSPEICMRVLRFAREHFCRGLEQDAYQYVMRHFVLVAQRSEDLLHLPIEELRSLVGADDLNVKSEEVVWELVLKWINHDPEARKCHIVDLLKNIRLGLLDTEFFLEKVKDHPYVTGNEACRPIIIETLKFLYDLEMITQKHGEVPTPEIARPRVPHEILFAICGWIGNGATSYMETYDTRADRWVQVREEDPSGPRAYHGVAAVGFSIYVVGGFNGRDYFSSCRCFNAVTKEWREVAPMNARRCYVSVAVVDDVVFAMGGYDGHYRQKTAERYNYRTNQWSLITPMAVQRSDASAATLNGKIYITGGFNGQECLSSAEVYDPETNQWTRIAPMRTRRSGQSCIAYHGCIYVIGGYNGIARMYSGEKYNPATNTWSPIPDMYNPRSNFAIEVIDDMIFAIGGFNGVTTIFHVECYDEKTNEWYEATDIGLHRSGLSACVIVGLPNVQDYIHKHREHLMEEKRQKLLALEFQRNQHQQQENQLIQDENDIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00905520;
90% Identity
iTF_00629219; iTF_01102186; iTF_01102930; iTF_01100729; iTF_01103676; iTF_01056171; iTF_01057771; iTF_01057015; iTF_00262770; iTF_00829634; iTF_00263653; iTF_01299400; iTF_00828896; iTF_01129458; iTF_00051123; iTF_00265851; iTF_00266581;
80% Identity
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